MX2014003478A - Metodo y composiciones para reducir los niveles sericos de triacilgliceridos en seres humanos con una lipasa fungica. - Google Patents

Metodo y composiciones para reducir los niveles sericos de triacilgliceridos en seres humanos con una lipasa fungica.

Info

Publication number
MX2014003478A
MX2014003478A MX2014003478A MX2014003478A MX2014003478A MX 2014003478 A MX2014003478 A MX 2014003478A MX 2014003478 A MX2014003478 A MX 2014003478A MX 2014003478 A MX2014003478 A MX 2014003478A MX 2014003478 A MX2014003478 A MX 2014003478A
Authority
MX
Mexico
Prior art keywords
triacylglycerides
compositions
methods
serum levels
human beings
Prior art date
Application number
MX2014003478A
Other languages
English (en)
Other versions
MX368742B (es
Inventor
Gregory Moore Kenneth
Schuler Christopher
Schuler Edward
S Penet Christopher
Gregory Kelly
Original Assignee
Bio Cat Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Cat Inc filed Critical Bio Cat Inc
Publication of MX2014003478A publication Critical patent/MX2014003478A/es
Publication of MX368742B publication Critical patent/MX368742B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

La invención se refiere a métodos y composiciones para reducir los niveles séricos de triacilglicéridos en sujetos humanos. En particular, la invención se refiere a la administración por vía oral de una cantidad eficaz de una formulación de lipasa fúngica a un sujeto humano que tiene niveles séricos elevados, o en el límite superior, de triacilglicéridos, durante un periodo de tiempo suficiente para reducir los niveles séricos de triacilglicéridos.
MX2014003478A 2011-09-23 2012-09-18 Metodo y composiciones para reducir los niveles sericos de triacilgliceridos en seres humanos con una lipasa fungica. MX368742B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/244,131 US8268305B1 (en) 2011-09-23 2011-09-23 Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase
PCT/US2012/055899 WO2013043587A1 (en) 2011-09-23 2012-09-18 Methods and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase

Publications (2)

Publication Number Publication Date
MX2014003478A true MX2014003478A (es) 2015-04-16
MX368742B MX368742B (es) 2019-10-14

Family

ID=46800675

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014003478A MX368742B (es) 2011-09-23 2012-09-18 Metodo y composiciones para reducir los niveles sericos de triacilgliceridos en seres humanos con una lipasa fungica.

Country Status (8)

Country Link
US (2) US8268305B1 (es)
EP (1) EP2758070B1 (es)
JP (1) JP6170051B2 (es)
AU (1) AU2012312661B2 (es)
BR (1) BR112014007042A8 (es)
CA (1) CA2849250C (es)
MX (1) MX368742B (es)
WO (1) WO2013043587A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201501081D0 (en) 2015-01-22 2015-03-11 Cilian Ag Use of enzymes with a wide pH activity range as medicaments for promoting digestion

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Also Published As

Publication number Publication date
AU2012312661A1 (en) 2014-03-20
US8268305B1 (en) 2012-09-18
US9555083B2 (en) 2017-01-31
BR112014007042A8 (pt) 2018-04-03
EP2758070B1 (en) 2019-11-06
BR112014007042A2 (pt) 2017-04-11
AU2012312661B2 (en) 2017-02-09
MX368742B (es) 2019-10-14
EP2758070A4 (en) 2015-03-25
EP2758070A1 (en) 2014-07-30
JP6170051B2 (ja) 2017-07-26
WO2013043587A1 (en) 2013-03-28
US20140294802A1 (en) 2014-10-02
JP2014526553A (ja) 2014-10-06
CA2849250A1 (en) 2013-03-28
CA2849250C (en) 2021-03-23

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