MX2014002787A - Organismos eucarioticos y metodos para producir 1, 3 -butanodiol. - Google Patents

Organismos eucarioticos y metodos para producir 1, 3 -butanodiol.

Info

Publication number
MX2014002787A
MX2014002787A MX2014002787A MX2014002787A MX2014002787A MX 2014002787 A MX2014002787 A MX 2014002787A MX 2014002787 A MX2014002787 A MX 2014002787A MX 2014002787 A MX2014002787 A MX 2014002787A MX 2014002787 A MX2014002787 A MX 2014002787A
Authority
MX
Mexico
Prior art keywords
butanediol
methods
eukaryotic organisms
producing
organisms
Prior art date
Application number
MX2014002787A
Other languages
English (en)
Spanish (es)
Inventor
Mark J Burk
Anthony P Burgard
Robin E Osterhout
Priti Pharkya
Jingyi Li
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of MX2014002787A publication Critical patent/MX2014002787A/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/16Dicarboxylic acids and dihydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/32Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Polymers & Plastics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MX2014002787A 2011-09-08 2012-09-07 Organismos eucarioticos y metodos para producir 1, 3 -butanodiol. MX2014002787A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201161532492P 2011-09-08 2011-09-08
US201161541951P 2011-09-30 2011-09-30
US201161558959P 2011-11-11 2011-11-11
US201261649039P 2012-05-18 2012-05-18
US201261655355P 2012-06-04 2012-06-04
PCT/US2012/054152 WO2013036764A1 (en) 2011-09-08 2012-09-07 Eukaryotic organisms and methods for producing 1,3-butanediol

Publications (1)

Publication Number Publication Date
MX2014002787A true MX2014002787A (es) 2014-12-08

Family

ID=47830417

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014002787A MX2014002787A (es) 2011-09-08 2012-09-07 Organismos eucarioticos y metodos para producir 1, 3 -butanodiol.

Country Status (11)

Country Link
US (2) US20130066035A1 (Direct)
EP (1) EP2753699A4 (Direct)
KR (1) KR20140058691A (Direct)
CN (1) CN103917651A (Direct)
BR (1) BR112014005352A2 (Direct)
CA (1) CA2848064A1 (Direct)
IN (1) IN2014CN02584A (Direct)
MX (1) MX2014002787A (Direct)
PH (1) PH12014500513A1 (Direct)
SG (1) SG11201400466TA (Direct)
WO (1) WO2013036764A1 (Direct)

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US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
BR112015006107A2 (pt) * 2012-09-24 2017-08-22 Showa Denko Kk Método para produzir um butanodiol
EP4403543A3 (en) 2013-03-15 2024-11-20 Genomatica, Inc. Process and systems for obtaining 1,4-butanediol from fermentation broths
EP2971021A4 (en) 2013-03-15 2016-12-21 Genomatica Inc MICROORGANISMS AND METHOD FOR THE PRODUCTION OF BUTADIENE AND RELATED COMPOUNDS BY FORMATASSIMILATION
EP3008178A1 (en) * 2013-06-14 2016-04-20 Technical University of Denmark Microbial production of 3-hydroxypropionic acid
WO2015057154A2 (en) 2013-10-18 2015-04-23 Biopetrolia Ab ENGINEERING OF ACETYL-CoA METABOLISM IN YEAST
EP3074504B1 (en) 2013-11-25 2024-12-25 Genomatica, Inc. Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol
WO2015084633A1 (en) 2013-12-03 2015-06-11 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
CN118879602A (zh) 2013-12-27 2024-11-01 基因组股份公司 具有增加的碳通量效率的方法和生物
DK3194604T3 (da) 2014-09-18 2020-05-25 Genomatica Inc Ikke-naturlig mikrobielle organismer med forbedret energisk effektivitet
US10173947B2 (en) 2014-12-12 2019-01-08 Versalis S.P.A. Process for the production of 1,3-butadiene from 1,3-butanediol
US10894750B2 (en) 2015-02-23 2021-01-19 Versalis S.P.A. Process for the dehydration of oxygenated compounds
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
WO2016196233A1 (en) 2015-05-30 2016-12-08 Genomatica, Inc. Vinylisomerase-dehydratases, alkenol dehydratases, linalool dehydratases and/ crotyl alcohol dehydratases and methods for making and using them
CN104988162B (zh) * 2015-06-08 2020-03-17 天津大学 辅因子再生模块在增强次级代谢产物在微生物中合成的应用
CN104988168A (zh) * 2015-06-08 2015-10-21 天津大学 乙酰辅酶a增强模块在增强7-脱氢胆甾醇在微生物中合成的应用
KR101704212B1 (ko) 2015-06-12 2017-02-08 씨제이제일제당 (주) 젖산을 생산하는 미생물 및 이를 이용한 젖산 제조 방법
WO2017006183A1 (en) * 2015-07-08 2017-01-12 Conradie Alex Van Eck Methods and host cells for enhancing production of 1,3-butanediol
CN107849522A (zh) * 2015-07-21 2018-03-27 多伦多大学管理委员会 用于产生1,3‑丁二醇的方法和微生物
ES2767728T3 (es) * 2015-10-06 2020-06-18 Dsm Ip Assets Bv Célula eucariota con elevada producción de producto de fermentación
CN108779153B (zh) 2015-10-30 2022-09-06 基因组股份公司 甲醇脱氢酶融合蛋白
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
MY206319A (en) 2017-03-31 2024-12-09 Genomatica Inc Aldehyde dehydrogenase variants and methods of use
EP3601547A1 (en) 2017-03-31 2020-02-05 Genomatica, Inc. 3-hydroxybutyryl-coa dehydrogenase variants and methods of use
CN110892073B (zh) * 2017-07-11 2024-03-01 安迪苏法国联合股份有限公司 增强型代谢物生产酵母
EP3652192A4 (en) * 2017-07-13 2021-10-06 Radici Chimica S.p.A. BIOLOGICAL PROCESSES FOR THE PREPARATION OF TERPENES
EP3652300A4 (en) * 2017-07-13 2021-06-23 Radici Chimica S.p.A. BIOLOGICAL PROCEDURES FOR MODIFYING CELLULAR CARBON FLOW
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
WO2020006058A2 (en) 2018-06-26 2020-01-02 Genomatica, Inc. Engineered microorganisms with g3p---> 3pg enzyme and/or fructose-1,6-bisphosphatase including those having synthetic or enhanced methylotrophy
IL281601B2 (en) 2018-09-21 2024-03-01 Versalis Spa Process for bio-1,3-butanediol purification from a fermentation broth
KR20210068489A (ko) 2018-09-26 2021-06-09 게노마티카 인코포레이티드 알데하이드 데하이드로게나제 변이체 및 이의 이용 방법
US20210332377A1 (en) * 2018-10-12 2021-10-28 Yield10 Bioscience, Inc. Genetically engineered plants that express a quinone-utilizing malate dehydrogenase
JP6668577B1 (ja) 2018-10-30 2020-03-18 GreenEarthInstitute株式会社 1,3−プロパンジオールの製造方法
CN110564662B (zh) * 2019-09-30 2022-03-25 南京农业大学 一种整合型高效表达乙醛脱氢酶枯草杆菌的构建方法
CN115873881A (zh) * 2021-09-30 2023-03-31 北京化工大学 一种产1,3-丁二醇的基因工程菌及其应用
CN117701489B (zh) * 2024-02-05 2024-05-10 北京绿色康成生物技术有限公司 一种提高大肠杆菌生产1,3-丁二醇的方法

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EP0827541B1 (en) * 1995-05-18 2009-11-18 University of Stellenbosch Nucleic acid sequence coding for a malate permease from s. pombe and uses thereof
EP2078092A2 (en) * 2006-09-28 2009-07-15 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
BRPI0909989A2 (pt) * 2008-06-05 2021-06-22 Butamax Advanced Biofuels Llc célula de levedura recombinante e método para a produção de um produto
EP2480673B1 (en) * 2009-09-27 2018-05-23 OPX Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
SG181607A1 (en) * 2009-12-10 2012-07-30 Genomatica Inc Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
US8871488B2 (en) * 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases

Also Published As

Publication number Publication date
US20170247709A1 (en) 2017-08-31
BR112014005352A2 (pt) 2017-03-28
AU2012304428A1 (en) 2013-05-02
PH12014500513A1 (en) 2014-05-12
WO2013036764A1 (en) 2013-03-14
KR20140058691A (ko) 2014-05-14
EP2753699A1 (en) 2014-07-16
US20130066035A1 (en) 2013-03-14
CN103917651A (zh) 2014-07-09
SG11201400466TA (en) 2014-04-28
CA2848064A1 (en) 2013-03-14
AU2012304428B2 (en) 2016-03-17
EP2753699A4 (en) 2015-08-19
IN2014CN02584A (Direct) 2015-08-07

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