MX2014001680A - Derivados de quinazolina-2, 4-diona. - Google Patents
Derivados de quinazolina-2, 4-diona.Info
- Publication number
- MX2014001680A MX2014001680A MX2014001680A MX2014001680A MX2014001680A MX 2014001680 A MX2014001680 A MX 2014001680A MX 2014001680 A MX2014001680 A MX 2014001680A MX 2014001680 A MX2014001680 A MX 2014001680A MX 2014001680 A MX2014001680 A MX 2014001680A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- alkoxy
- halogen
- quinazoline
- attachment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2011053583 | 2011-08-11 | ||
| PCT/IB2012/054080 WO2013021363A1 (en) | 2011-08-11 | 2012-08-10 | Quinazoline-2,4-dione derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2014001680A true MX2014001680A (es) | 2014-05-27 |
Family
ID=47010655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014001680A MX2014001680A (es) | 2011-08-11 | 2012-08-10 | Derivados de quinazolina-2, 4-diona. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8916573B2 (ko) |
| EP (1) | EP2742042A1 (ko) |
| JP (1) | JP2014525396A (ko) |
| KR (1) | KR20140054057A (ko) |
| CN (1) | CN103732593A (ko) |
| AU (1) | AU2012293329A1 (ko) |
| BR (1) | BR112014003200A2 (ko) |
| CA (1) | CA2842885A1 (ko) |
| MX (1) | MX2014001680A (ko) |
| RU (1) | RU2014108919A (ko) |
| WO (1) | WO2013021363A1 (ko) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014024056A1 (en) | 2012-08-06 | 2014-02-13 | Daiichi Sankyo Company, Limited | Pyrrolidine derivatives with antibacterial properties |
| WO2014058349A1 (ru) | 2012-10-10 | 2014-04-17 | Ikonomov Artashes Valeryevich | Электронная платежная система |
| WO2015066413A1 (en) * | 2013-11-01 | 2015-05-07 | Novartis Ag | Oxazolidinone hydroxamic acid compounds for the treatment of bacterial infections |
| AR102256A1 (es) * | 2014-10-15 | 2017-02-15 | Actelion Pharmaceuticals Ltd | Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi |
| BR112018016208A2 (pt) * | 2016-02-08 | 2018-12-18 | Redx Pharma Plc | compostos heterocíclicos, em particular derivados 2-oxo-4,4,5,5,6,6,7,7-octahidrobenzoxazol, e seus usos como compostos antibacterianos |
| GB201602235D0 (en) * | 2016-02-08 | 2016-03-23 | Redx Pharma Plc | Antibacterial compounds |
| WO2017137743A1 (en) * | 2016-02-08 | 2017-08-17 | Redx Pharma Plc | Antibacterial compounds |
| US11395820B2 (en) | 2016-03-16 | 2022-07-26 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Small molecules against cereblon to enhance effector t cell function |
| CN106146414A (zh) * | 2016-07-07 | 2016-11-23 | 浙江大学 | 喹唑啉二酮类衍生物及其制备方法和用途 |
| PT3634968T (pt) * | 2017-06-08 | 2023-04-14 | Bugworks Res Inc | Compostos heterocíclicos úteis como agentes anti-bacterianos e método para a sua produção |
| JP7390728B2 (ja) | 2017-11-29 | 2023-12-04 | バグワークス・リサーチ・インコーポレイテッド | 抗菌複素環式化合物及びそれらの合成 |
| WO2019186590A1 (en) * | 2018-03-28 | 2019-10-03 | Bugworks Research India Pvt Ltd | Oxazolidinone antibiotic compounds and process of preparation |
| WO2020014489A2 (en) | 2018-07-11 | 2020-01-16 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Dimeric immuno-modulatory compounds against cereblon-based mechanisms |
| WO2023175185A1 (en) | 2022-03-17 | 2023-09-21 | Forx Therapeutics Ag | 2,4-dioxo-1,4-dihydroquinazoline derivatives as parg inhibitors for the treatment of cancer |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998042688A1 (fr) | 1997-03-26 | 1998-10-01 | Sumitomo Pharmaceuticals Co., Ltd. | Derives de 4-arylmethylene-1,4-dihydro-2h-azine |
| AU2001246893A1 (en) | 2000-04-18 | 2001-10-30 | Sumitomo Pharmaceuticals Company, Limited | Tricyclic quinazolinediones |
| DE10316081A1 (de) * | 2003-04-08 | 2004-10-21 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
| MXPA06005550A (es) | 2003-11-18 | 2006-08-17 | Warner Lambert Co | Agentes antibacterianos. |
| AU2005279050A1 (en) | 2004-07-30 | 2006-03-09 | Centre National De La Recherche Scientifique (Cnrs) | Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, and the synthesis and uses thereof as antibacterial agents |
| FR2873695A1 (fr) * | 2004-07-30 | 2006-02-03 | Palumed Sa | Molecules hybrides qa ou q est une aminoquinoleine et a est un antibiotique ou un inhibiteur de resistance), leur synthese et leurs utilisations en tant qu'agent antibacterien |
| MY150958A (en) | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| EP1960363B1 (en) | 2005-12-09 | 2014-01-22 | Amgen, Inc. | Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, compositions and uses thereof |
| CL2008001002A1 (es) | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| CL2008001003A1 (es) | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| WO2009104147A2 (en) | 2008-02-20 | 2009-08-27 | Actelion Pharmaceuticals Ltd | Azatricyclic antibiotic compounds |
| US8349826B2 (en) * | 2008-02-22 | 2013-01-08 | Actelion Pharmaceuticals Ltd. | Oxazolidinone derivatives |
| JP2011529960A (ja) * | 2008-08-04 | 2011-12-15 | アクテリオン ファーマシューティカルズ リミテッド | 三環式アルキルアミノメチルオキサゾリジノン誘導体 |
| PT2344495E (pt) | 2008-10-07 | 2015-04-01 | Actelion Pharmaceuticals Ltd | Compostos antibióticos de oxazolidinona tricíclica |
| EP2346862B1 (en) | 2008-10-10 | 2012-09-12 | Actelion Pharmaceuticals Ltd. | 2-benzothiophenyl-and 2-naphthyl-0xaz0lidin0nes and their azaisostere analogues as antibacterial agents |
| WO2010045987A1 (en) | 2008-10-23 | 2010-04-29 | Glaxo Group Limited | Substituted (aza) -1-methyl-1h-quin0lin-2-0nes as antibacterials |
| DE102009004393A1 (de) | 2009-01-08 | 2010-11-11 | Eads Deutschland Gmbh | Akkumulierender Feuchtesensor |
-
2012
- 2012-08-10 BR BR112014003200A patent/BR112014003200A2/pt not_active IP Right Cessation
- 2012-08-10 CA CA2842885A patent/CA2842885A1/en not_active Abandoned
- 2012-08-10 AU AU2012293329A patent/AU2012293329A1/en not_active Abandoned
- 2012-08-10 MX MX2014001680A patent/MX2014001680A/es unknown
- 2012-08-10 EP EP12770233.0A patent/EP2742042A1/en not_active Withdrawn
- 2012-08-10 RU RU2014108919/04A patent/RU2014108919A/ru not_active Application Discontinuation
- 2012-08-10 CN CN201280039106.1A patent/CN103732593A/zh active Pending
- 2012-08-10 WO PCT/IB2012/054080 patent/WO2013021363A1/en active Application Filing
- 2012-08-10 US US14/238,415 patent/US8916573B2/en not_active Expired - Fee Related
- 2012-08-10 JP JP2014524478A patent/JP2014525396A/ja active Pending
- 2012-08-10 KR KR1020147003771A patent/KR20140054057A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013021363A1 (en) | 2013-02-14 |
| US8916573B2 (en) | 2014-12-23 |
| CN103732593A (zh) | 2014-04-16 |
| EP2742042A1 (en) | 2014-06-18 |
| CA2842885A1 (en) | 2013-02-14 |
| BR112014003200A2 (pt) | 2017-04-04 |
| AU2012293329A1 (en) | 2014-03-27 |
| RU2014108919A (ru) | 2015-09-20 |
| KR20140054057A (ko) | 2014-05-08 |
| US20140171425A1 (en) | 2014-06-19 |
| JP2014525396A (ja) | 2014-09-29 |
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