MX2013011413A - Tratamiento terapeutico. - Google Patents

Tratamiento terapeutico.

Info

Publication number
MX2013011413A
MX2013011413A MX2013011413A MX2013011413A MX2013011413A MX 2013011413 A MX2013011413 A MX 2013011413A MX 2013011413 A MX2013011413 A MX 2013011413A MX 2013011413 A MX2013011413 A MX 2013011413A MX 2013011413 A MX2013011413 A MX 2013011413A
Authority
MX
Mexico
Prior art keywords
taxane
compound
relates
treatment
therapeutic treatment
Prior art date
Application number
MX2013011413A
Other languages
English (en)
Other versions
MX357447B (es
Inventor
Barry Robert Davies
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2013011413A publication Critical patent/MX2013011413A/es
Publication of MX357447B publication Critical patent/MX357447B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a una combinación que comprende (S)-4-amino-N-(1-(4-clorofenil)-3-hidroxipropil)-1-(7H-pirrolo[2, 3-d]pirimidin-4-iI)piperidin-4-carboxamida, o una sal farmacéuticamente aceptable de lo mismo, en lo sucesivo en la presente "Compuesto (I)", y un taxano. Los taxanos incluyen fármacos contra el cáncer establecidos tales como docetaxel (TaxotereTM) y paclitaxel (TaxolTM). Tales combinaciones pueden ser útiles en el tratamiento o la profilaxis del cáncer. La invención también se refiere a una composición farmacéutica que comprende tal Compuesto (I) y un taxano. La invención se refiere además a un método de tratamiento que comprende la administración simultánea, secuencial o por separado del Compuesto (I) y un taxano a un animal de sangre caliente como un humano. La invención también se refiere a un kit que comprende el Compuesto (I) y un taxano, opcionalmente con instrucciones de uso.
MX2013011413A 2011-04-01 2012-04-02 Tratamiento terapeutico. MX357447B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161470668P 2011-04-01 2011-04-01
PCT/GB2012/050736 WO2012131399A1 (en) 2011-04-01 2012-04-02 Therapeutic treatment

Publications (2)

Publication Number Publication Date
MX2013011413A true MX2013011413A (es) 2014-05-21
MX357447B MX357447B (es) 2018-07-10

Family

ID=45976963

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013011413A MX357447B (es) 2011-04-01 2012-04-02 Tratamiento terapeutico.

Country Status (26)

Country Link
US (2) US9402847B2 (es)
EP (2) EP3620159A1 (es)
JP (1) JP6080837B2 (es)
KR (1) KR101851820B1 (es)
CN (1) CN103442708B (es)
AU (1) AU2012235902B2 (es)
BR (1) BR112013025410A2 (es)
CA (1) CA2831848C (es)
CY (1) CY1122608T1 (es)
DK (1) DK2694056T3 (es)
EA (1) EA027506B1 (es)
ES (1) ES2761311T3 (es)
HR (1) HRP20191927T1 (es)
HU (1) HUE047357T2 (es)
IL (1) IL228589B (es)
LT (1) LT2694056T (es)
ME (1) ME03589B (es)
MX (1) MX357447B (es)
MY (1) MY169449A (es)
PL (1) PL2694056T3 (es)
PT (1) PT2694056T (es)
RS (1) RS59568B1 (es)
SG (1) SG193505A1 (es)
SI (1) SI2694056T1 (es)
WO (1) WO2012131399A1 (es)
ZA (1) ZA201308176B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2694056T3 (da) * 2011-04-01 2020-01-02 Astrazeneca Ab Terapeutisk behandling
ES2754034T3 (es) * 2013-03-04 2020-04-15 Astrazeneca Ab Combinación para el tratamiento de cáncer
CN107670048B (zh) * 2017-08-30 2019-04-26 南京明臻医药科技有限公司 具有协同抗癌活性的中间体药物和聚乙二醇偶联协同抗癌药物、及其制备方法和应用

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Also Published As

Publication number Publication date
SG193505A1 (en) 2013-10-30
PL2694056T3 (pl) 2020-03-31
EA027506B1 (ru) 2017-08-31
JP6080837B2 (ja) 2017-02-15
CA2831848C (en) 2020-12-22
HUE047357T2 (hu) 2020-04-28
WO2012131399A1 (en) 2012-10-04
PT2694056T (pt) 2019-11-20
MX357447B (es) 2018-07-10
CN103442708A (zh) 2013-12-11
DK2694056T3 (da) 2020-01-02
EP2694056B1 (en) 2019-10-16
CA2831848A1 (en) 2012-10-04
KR20140022856A (ko) 2014-02-25
ZA201308176B (en) 2015-12-23
SI2694056T1 (sl) 2019-12-31
KR101851820B1 (ko) 2018-06-04
HRP20191927T1 (hr) 2020-01-10
IL228589B (en) 2019-09-26
EP3620159A1 (en) 2020-03-11
ME03589B (me) 2020-07-20
EP2694056A1 (en) 2014-02-12
JP2014509639A (ja) 2014-04-21
US20160317540A1 (en) 2016-11-03
MY169449A (en) 2019-04-11
AU2012235902A1 (en) 2013-05-02
AU2012235902B2 (en) 2015-08-27
BR112013025410A2 (pt) 2016-12-20
US9402847B2 (en) 2016-08-02
NZ616410A (en) 2015-09-25
RS59568B1 (sr) 2019-12-31
LT2694056T (lt) 2019-12-10
IL228589A0 (en) 2013-12-31
CN103442708B (zh) 2016-11-09
US20140121227A1 (en) 2014-05-01
ES2761311T3 (es) 2020-05-19
CY1122608T1 (el) 2021-03-12
EA201391327A1 (ru) 2014-03-31

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