MX2013004260A - Uso de deposito de fosfolipidos viscosos estables en almacenamiento para tratar heridas. - Google Patents

Uso de deposito de fosfolipidos viscosos estables en almacenamiento para tratar heridas.

Info

Publication number
MX2013004260A
MX2013004260A MX2013004260A MX2013004260A MX2013004260A MX 2013004260 A MX2013004260 A MX 2013004260A MX 2013004260 A MX2013004260 A MX 2013004260A MX 2013004260 A MX2013004260 A MX 2013004260A MX 2013004260 A MX2013004260 A MX 2013004260A
Authority
MX
Mexico
Prior art keywords
depot
water
storage stable
treat wounds
stable viscous
Prior art date
Application number
MX2013004260A
Other languages
English (en)
Other versions
MX354575B (es
Inventor
Franklin Okumu
Hailiang Chen
Xian Chen Andrew
Dushyanth Surakanti
Original Assignee
Reddys Lab Inc Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reddys Lab Inc Dr filed Critical Reddys Lab Inc Dr
Publication of MX2013004260A publication Critical patent/MX2013004260A/es
Publication of MX354575B publication Critical patent/MX354575B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona un método para prevenir y/o tratar una infección de herida al introducir a una herida un depósito transparente que comprende un agente(s) farmacéuticamente activo soluble en agua hidrofílicos seleccionado del grupo que consiste de vancomicina, gentamicina, y una mezcla de las mismas, agua, un fosfolípido, un aceite, un agente ajustador de pH, y un agente modificador de viscosidad, en donde el agua presente en el depósito no es más que aproximadamente 4% en peso, no más que aproximadamente 2% en peso, no más que al menos 1% en peso del agua relativo con el peso total del deposito.
MX2013004260A 2010-10-22 2011-10-18 Uso de depósito de fosfolípidos viscosos estables en almacenamiento para tratar heridas.. MX354575B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40571510P 2010-10-22 2010-10-22
PCT/US2011/056661 WO2012054447A2 (en) 2010-10-22 2011-10-18 Use of storage stable viscous phospholipid depot to treat wounds

Publications (2)

Publication Number Publication Date
MX2013004260A true MX2013004260A (es) 2013-07-05
MX354575B MX354575B (es) 2018-03-12

Family

ID=45975829

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013004260A MX354575B (es) 2010-10-22 2011-10-18 Uso de depósito de fosfolípidos viscosos estables en almacenamiento para tratar heridas..

Country Status (18)

Country Link
US (1) US20140155320A1 (es)
EP (1) EP2629779B1 (es)
JP (1) JP5877843B2 (es)
KR (1) KR101957177B1 (es)
CN (1) CN103179972A (es)
AU (1) AU2011317237B2 (es)
BR (1) BR112013009743A2 (es)
CA (1) CA2814577C (es)
DK (1) DK2629779T3 (es)
ES (1) ES2640756T3 (es)
MX (1) MX354575B (es)
NZ (1) NZ608406A (es)
PL (1) PL2629779T3 (es)
PT (1) PT2629779T (es)
RU (1) RU2578437C2 (es)
SI (1) SI2629779T1 (es)
WO (1) WO2012054447A2 (es)
ZA (1) ZA201302116B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104427976B (zh) 2012-05-10 2018-04-24 佩因拉佛姆有限公司 疏水的活性成分的储库制剂及其制备方法
US9616098B2 (en) 2013-05-30 2017-04-11 Scidose, Llc Formulations of vancomycin
CN108601730B (zh) 2016-01-15 2021-10-26 赛多斯制药有限责任公司 万古霉素的制剂
EP3579891A4 (en) * 2017-02-08 2021-01-06 HKL Medical, LLC INTRASITE ADMINISTRATION AND DOSAGE PROCEDURES AND PHARMACEUTICAL PRODUCTS FOR USE THEREIN

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JPS61194015A (ja) * 1985-02-21 1986-08-28 Taisho Pharmaceut Co Ltd 外用剤
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SI9300468A (en) * 1992-10-14 1994-06-30 Hoffmann La Roche Injectable composition for the sustained release of biologically active compounds
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US5660854A (en) 1994-11-28 1997-08-26 Haynes; Duncan H Drug releasing surgical implant or dressing material
US5654337A (en) * 1995-03-24 1997-08-05 II William Scott Snyder Topical formulation for local delivery of a pharmaceutically active agent
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US6413556B1 (en) * 1999-01-08 2002-07-02 Sky High, Llc Aqueous anti-apoptotic compositions
US7799004B2 (en) 2001-03-05 2010-09-21 Kci Licensing, Inc. Negative pressure wound treatment apparatus and infection identification system and method
SE0000730D0 (sv) * 2000-03-06 2000-03-06 Scotia Holdings Plc Lipid carrier
US20040151765A1 (en) * 2001-09-18 2004-08-05 Ritchie Branson W. Methods and compositions for wound management
IL139177A0 (en) 2000-10-20 2001-11-25 S C Republic Dev S R L Sustained release drug delivery system
JP4958381B2 (ja) * 2000-12-19 2012-06-20 ザ・ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システム 胃腸管保護および治療活性増強のためのレシチン油およびｎｓａｉｄｓの製剤を用いる方法および組成物
US20040147534A1 (en) * 2003-01-23 2004-07-29 Foote Mary Ann Topical composition and method for treating occlusive wounds
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Also Published As

Publication number Publication date
AU2011317237B2 (en) 2015-02-05
JP2013540155A (ja) 2013-10-31
RU2013123362A (ru) 2014-11-27
AU2011317237A1 (en) 2013-04-11
WO2012054447A3 (en) 2012-08-16
JP5877843B2 (ja) 2016-03-08
KR101957177B1 (ko) 2019-03-12
BR112013009743A2 (pt) 2016-07-19
EP2629779B1 (en) 2017-06-21
PL2629779T3 (pl) 2017-12-29
MX354575B (es) 2018-03-12
ES2640756T3 (es) 2017-11-06
SI2629779T1 (sl) 2017-11-30
KR20130122939A (ko) 2013-11-11
EP2629779A2 (en) 2013-08-28
CA2814577C (en) 2019-06-04
WO2012054447A2 (en) 2012-04-26
CN103179972A (zh) 2013-06-26
RU2578437C2 (ru) 2016-03-27
NZ608406A (en) 2015-06-26
EP2629779A4 (en) 2015-02-25
ZA201302116B (en) 2014-05-28
PT2629779T (pt) 2017-09-22
DK2629779T3 (en) 2017-10-02
US20140155320A1 (en) 2014-06-05
CA2814577A1 (en) 2012-04-26

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