MX2022007904A - Composiciones y usos de polipeptidos cationicos, sinteticos, antimicrobianos localmente aplicados con seguridad y desempe?o mejorados. - Google Patents
Composiciones y usos de polipeptidos cationicos, sinteticos, antimicrobianos localmente aplicados con seguridad y desempe?o mejorados.Info
- Publication number
- MX2022007904A MX2022007904A MX2022007904A MX2022007904A MX2022007904A MX 2022007904 A MX2022007904 A MX 2022007904A MX 2022007904 A MX2022007904 A MX 2022007904A MX 2022007904 A MX2022007904 A MX 2022007904A MX 2022007904 A MX2022007904 A MX 2022007904A
- Authority
- MX
- Mexico
- Prior art keywords
- antimicrobial
- pharmaceutical composition
- compositions
- safety
- aqueous carrier
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
- A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Materials Engineering (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Se formulan composiciones farmacéuticas antimicrobianas para permitir aplicación local in vivo de dosis que proporcionan eficacia antimicrobiana con bajo riesgo de toxicidades de tejido local y/o bajo riesgo de toxicidades sistémicas/distantes de órganos. En diferentes modalidades las composiciones farmacéuticas antimicrobianas comprenden polipéptidos catiónicos, sintéticos, antimicrobianos que se dispersan en un portador acuoso y se formulan para lograr un grado deseado de auto-montaje y/o viscosidad de composición.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762482630P | 2017-04-06 | 2017-04-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022007904A true MX2022007904A (es) | 2022-07-21 |
Family
ID=63712780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022007904A MX2022007904A (es) | 2017-04-06 | 2019-10-03 | Composiciones y usos de polipeptidos cationicos, sinteticos, antimicrobianos localmente aplicados con seguridad y desempe?o mejorados. |
Country Status (12)
Country | Link |
---|---|
US (2) | US11285189B2 (es) |
EP (1) | EP3606543A4 (es) |
JP (2) | JP2020513016A (es) |
KR (1) | KR20200018400A (es) |
CN (1) | CN110740744A (es) |
AU (2) | AU2018249552A1 (es) |
BR (1) | BR112019020781A2 (es) |
CA (1) | CA3058901A1 (es) |
MX (1) | MX2022007904A (es) |
RU (1) | RU2019133628A (es) |
SG (1) | SG11201909016TA (es) |
WO (1) | WO2018187617A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6224069B2 (ja) | 2012-03-23 | 2017-11-01 | アミクローブ,インコーポレイテッド | 組織適合特性を有する抗菌剤の組成物および使用 |
RU2019133628A (ru) | 2017-04-06 | 2021-05-06 | Амикроб, Инк. | Композиции и применения антимикробных средств для местного применения с улучшенными характеристиками и безопасностью |
EP4055029A4 (en) | 2019-11-08 | 2023-11-22 | University of Pittsburgh - of the Commonwealth System of Higher Education | COMPOSITIONS COMPRISING ANTIMICROBIAL PEPTIDES |
CN115397454A (zh) * | 2020-03-31 | 2022-11-25 | 立美基股份有限公司 | 通过辐照对自组装肽进行灭菌 |
CA3179706A1 (en) * | 2020-04-08 | 2021-10-14 | Amicrobe, Inc. | Compositions and uses of locally applied synthetic amino acid polymers for prevention and treatment of viral infections |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5636643A (en) | 1991-11-14 | 1997-06-10 | Wake Forest University | Wound treatment employing reduced pressure |
US6632922B1 (en) | 1998-03-19 | 2003-10-14 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
US6680365B1 (en) | 1998-03-19 | 2004-01-20 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
US6686446B2 (en) | 1998-03-19 | 2004-02-03 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
TW570805B (en) | 1998-09-01 | 2004-01-11 | Hoffmann La Roche | Water-soluble pharmaceutical composition in an ionic complex |
US8206749B1 (en) | 1999-02-26 | 2012-06-26 | Novartis Vaccines And Diagnostics, Inc. | Microemulsions with adsorbed macromolecules and microparticles |
DK1322287T3 (da) | 2000-09-28 | 2006-07-24 | Chiron Corp | Mikropartikler til administration af heterologe nukleinsyrer |
US6835536B2 (en) * | 2001-08-21 | 2004-12-28 | Micrologix Biotech Inc. | Antimicrobial cationic peptides and formulations thereof |
US6818732B2 (en) | 2001-08-30 | 2004-11-16 | The Regents Of The University Of California | Transition metal initiators for controlled poly (beta-peptide) synthesis from beta-lactam monomers |
JP2003171463A (ja) * | 2001-12-06 | 2003-06-20 | Chisso Corp | ポリリジン及びその製造法 |
WO2003067311A1 (fr) | 2002-02-07 | 2003-08-14 | Ophtecs Corporation | Solution pour lentilles de contact |
US20050004002A1 (en) | 2002-12-09 | 2005-01-06 | American Bioscience, Inc. | Compositions and methods of delivery of pharmacological agents |
EP1644382B1 (en) | 2003-07-11 | 2008-03-05 | Theravance, Inc. | Cross-linked glycopeptide-cephalosporin antibiotics |
WO2005018701A1 (en) | 2003-08-25 | 2005-03-03 | Kane Biotech Inc. | Synergistic antimicrobial compositions and methods of inhibiting biofilm formation |
JP5015604B2 (ja) | 2003-12-30 | 2012-08-29 | バイオアクティブ ポリマーズ アクティエボラーグ | 曝露された生物組織の表面保護 |
EP1722819B1 (en) * | 2004-03-12 | 2007-12-26 | Intercell AG | Method for solubilising peptide mixtures |
JP5020078B2 (ja) | 2004-08-18 | 2012-09-05 | ノバビオティクス・リミテッド | ペプチド |
CN101189256B (zh) | 2005-06-06 | 2014-05-21 | 诺维信阿德宁生物技术公司 | 具有抗微生物活性的多肽和编码该多肽的多核苷酸 |
US20080139450A1 (en) | 2005-07-01 | 2008-06-12 | Srinivasa Madhyastha | Antimicrobial Compositions and Uses Thereof |
US20070190110A1 (en) | 2006-02-10 | 2007-08-16 | Pameijer Cornelis H | Agents and devices for providing blood clotting functions to wounds |
WO2008070571A2 (en) | 2006-12-01 | 2008-06-12 | The Regents Of The University Of California | Vesicles of self-assembling block copolymers and methods for making and using the same |
CA2691645A1 (en) | 2007-06-25 | 2008-12-31 | Lipopeptide Ab | New medical products |
EP2192923A2 (en) | 2007-08-27 | 2010-06-09 | Massachusetts Institute of Technology | Bi-functional polymer-attached inhibitors of influenza virus |
US20110098344A1 (en) | 2008-06-19 | 2011-04-28 | Nippon Shinyaku Co., Ltd. | Drug carrier |
EP2349310B1 (en) | 2008-10-20 | 2014-07-23 | Moerae Matrix, Inc. | Polypeptide for treating or preventing adhesions |
JP5752051B2 (ja) | 2009-01-23 | 2015-07-22 | ケーン バイオテク インコーポレーテッド | バイオフィルム除去用抗菌性組成物およびその使用 |
GB0905451D0 (en) | 2009-03-31 | 2009-05-13 | Novabiotics Ltd | Biofilms |
BR112012026880B1 (pt) | 2010-04-27 | 2021-03-16 | Lysando Ag | método para eliminação ou redução de um biofilme bacteriano, variante de endolisina ou variante de bacteriocina e seus usos |
ES2622498T3 (es) | 2010-08-23 | 2017-07-06 | The Regents Of The University Of California | Composiciones y usos de materiales con actividad antimicrobiana elevada y toxicidad baja |
CN103370087A (zh) * | 2011-01-19 | 2013-10-23 | 目立康株式会社 | 隐形眼镜用液体制剂 |
US9781949B2 (en) | 2011-03-31 | 2017-10-10 | The University Of Massachusetts | Antimicrobial delivery systems, methods of manufacture, and methods of use thereof |
JP6224069B2 (ja) * | 2012-03-23 | 2017-11-01 | アミクローブ,インコーポレイテッド | 組織適合特性を有する抗菌剤の組成物および使用 |
DE102014101663A1 (de) | 2014-02-11 | 2015-08-13 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Synthetische artifizielle Peptide mit antimikrobieller Wirkung |
EP3194422B1 (en) | 2014-09-19 | 2020-04-29 | Tensive Controls, Inc. | Anti-microbial peptides |
AU2015338969B2 (en) * | 2014-10-30 | 2020-08-27 | Biomet Manufacturing, Llc | Methods of preventing surgical site infections |
JP2016113373A (ja) * | 2014-12-11 | 2016-06-23 | エスポ化学株式会社 | 抗菌性、抗ウイルス性を有する水溶性組成物 |
RU2019133628A (ru) | 2017-04-06 | 2021-05-06 | Амикроб, Инк. | Композиции и применения антимикробных средств для местного применения с улучшенными характеристиками и безопасностью |
JP2021514985A (ja) | 2018-03-02 | 2021-06-17 | ジャニュアリー セラピューティクス,インク. | ナノ粒子組成物 |
-
2018
- 2018-04-05 RU RU2019133628A patent/RU2019133628A/ru unknown
- 2018-04-05 WO PCT/US2018/026322 patent/WO2018187617A1/en active Search and Examination
- 2018-04-05 US US16/500,288 patent/US11285189B2/en active Active
- 2018-04-05 EP EP18780547.8A patent/EP3606543A4/en active Pending
- 2018-04-05 CA CA3058901A patent/CA3058901A1/en active Pending
- 2018-04-05 CN CN201880037998.9A patent/CN110740744A/zh active Pending
- 2018-04-05 AU AU2018249552A patent/AU2018249552A1/en not_active Abandoned
- 2018-04-05 KR KR1020197032623A patent/KR20200018400A/ko not_active IP Right Cessation
- 2018-04-05 BR BR112019020781A patent/BR112019020781A2/pt unknown
- 2018-04-05 JP JP2019554855A patent/JP2020513016A/ja active Pending
- 2018-04-05 SG SG11201909016T patent/SG11201909016TA/en unknown
-
2019
- 2019-10-03 MX MX2022007904A patent/MX2022007904A/es unknown
-
2022
- 2022-03-08 US US17/654,021 patent/US20230017994A1/en active Pending
-
2023
- 2023-02-27 JP JP2023028902A patent/JP2023054375A/ja active Pending
- 2023-04-13 AU AU2023202283A patent/AU2023202283A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN110740744A (zh) | 2020-01-31 |
EP3606543A1 (en) | 2020-02-12 |
US20210100867A1 (en) | 2021-04-08 |
WO2018187617A1 (en) | 2018-10-11 |
US11285189B2 (en) | 2022-03-29 |
KR20200018400A (ko) | 2020-02-19 |
RU2019133628A3 (es) | 2021-07-14 |
JP2020513016A (ja) | 2020-04-30 |
JP2023054375A (ja) | 2023-04-13 |
CA3058901A1 (en) | 2018-10-11 |
WO2018187617A8 (en) | 2019-10-17 |
SG11201909016TA (en) | 2019-10-30 |
AU2023202283A1 (en) | 2023-05-11 |
RU2019133628A (ru) | 2021-05-06 |
BR112019020781A2 (pt) | 2020-04-28 |
EP3606543A4 (en) | 2020-12-16 |
US20230017994A1 (en) | 2023-01-19 |
AU2018249552A1 (en) | 2019-10-31 |
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