MX2013000250A - Polipeptidos cortos y que contienen d-aminoacido para conjugados terapeuticos y usos de los mismos. - Google Patents
Polipeptidos cortos y que contienen d-aminoacido para conjugados terapeuticos y usos de los mismos.Info
- Publication number
- MX2013000250A MX2013000250A MX2013000250A MX2013000250A MX2013000250A MX 2013000250 A MX2013000250 A MX 2013000250A MX 2013000250 A MX2013000250 A MX 2013000250A MX 2013000250 A MX2013000250 A MX 2013000250A MX 2013000250 A MX2013000250 A MX 2013000250A
- Authority
- MX
- Mexico
- Prior art keywords
- arg
- gly
- lys
- tyr
- neurotensin
- Prior art date
Links
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| WO2007009229A1 (en) | 2005-07-15 | 2007-01-25 | Angiochem Inc. | Use of aprotinin polypeptides as carriers in pharmaceutical conjugates |
| US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| WO2010043047A1 (en) | 2008-10-15 | 2010-04-22 | Angiochem Inc. | Conjugates of glp-1 agonists and uses thereof |
| US9914754B2 (en) | 2008-12-05 | 2018-03-13 | Angiochem Inc. | Conjugates of neurotensin or neurotensin analogs and uses thereof |
| AU2009327267A1 (en) | 2008-12-17 | 2011-07-14 | Angiochem, Inc. | Membrane type-1 matrix metalloprotein inhibitors and uses thereof |
| ES2729261T3 (es) | 2009-04-20 | 2019-10-31 | Angiochem Inc | Tratamiento del cáncer de ovario utilizando un agente anticancerígeno conjugado con un análogo de Angiopep-2 |
| WO2011000095A1 (en) | 2009-07-02 | 2011-01-06 | Angiochem Inc. | Multimeric peptide conjugates and uses thereof |
| EP2885321A4 (en) * | 2012-08-14 | 2016-03-30 | Angiochem Inc | CONJUGATES WITH AN ANTIBODY PART, A POLYPEPTIDE THROUGH THE BLOOD BRAIN BARRIER, AND A CYTOTOXIN |
| JP2015526434A (ja) | 2012-08-14 | 2015-09-10 | アンジオケム インコーポレーテッド | ペプチド−デンドリマーコンジュゲート及びその使用 |
| CN105026432A (zh) * | 2012-11-12 | 2015-11-04 | 安吉奥开米公司 | 抑肽酶衍生的多肽-抗体缀合物 |
| EP2896402A1 (en) | 2014-01-20 | 2015-07-22 | Vect-Horus | Activated neurotensin molecules and the uses thereof |
| EP3307326B9 (en) | 2015-06-15 | 2021-02-24 | Angiochem Inc. | Methods for the treatment of leptomeningeal carcinomatosis |
| PL3393496T3 (pl) | 2015-12-23 | 2024-04-22 | The Johns Hopkins University | Długo działający agonista glp-1r jako terapia stanów neurologicznych i neurodegeneracyjnych |
| CN106267231A (zh) * | 2016-08-29 | 2017-01-04 | 苏州普罗达生物科技有限公司 | 一种小分子cd19抗体多肽与环磷酰胺偶联的结合物 |
| BR112020005271A2 (pt) | 2017-10-02 | 2020-09-15 | Denali Therapeutics Inc. | proteína, polipeptídeo, polinucleotídeo, vetor, célula hospedeira, método para produção de um polipeptídeo, métodos de tratamento de um distúrbio, de diminuição do acúmulo, de monitoramento, de transporte de um agente e de tratamento de um lsd e composição farmacêutica |
| CN110551203B (zh) * | 2019-09-25 | 2023-02-10 | 成都奥达生物科技有限公司 | 一种艾塞那肽类似物 |
| CN112079841B (zh) * | 2020-09-22 | 2022-04-26 | 武汉天马微电子有限公司 | 一种有机化合物、电致发光材料及其应用 |
| CN114187967B (zh) * | 2021-12-28 | 2024-10-29 | 大连工业大学 | 一种面向降血压肽活性的氨基酸序列预测方法 |
| WO2024192242A2 (en) * | 2023-03-14 | 2024-09-19 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods relating to age-related, neurological, and vascular disease conditions |
| CN120733009B (zh) * | 2025-08-29 | 2025-11-04 | 天津尤金生物科技有限公司 | 一种具有减肥功效的复合活性多肽组合物及其制备方法 |
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| GB1518390A (en) | 1976-03-30 | 1978-07-19 | Farmaceutici Italia | Doxorubicin thioesters |
| US4301277A (en) | 1980-10-20 | 1981-11-17 | Sri International | 3-Deamino-3-(4-morpholinyl) derivatives of daunorubicin and doxorubicin |
| US4314054A (en) | 1981-03-23 | 1982-02-02 | Sri International | 3'-Deamino-3'-(4-methoxy-1-piperidinyl) derivatives of daunorubicin and doxorubicin |
| US4464529A (en) | 1982-07-20 | 1984-08-07 | Sri International | Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin |
| US4826964A (en) | 1982-07-20 | 1989-05-02 | Sri International | Bridged oxygen analogs of daunorubcin and doxorubicin |
| US4507466A (en) | 1983-01-07 | 1985-03-26 | The Dow Chemical Corporation | Dense star polymers having core, core branches, terminal groups |
| US4585859A (en) | 1983-05-24 | 1986-04-29 | Sri International | Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin |
| US4567253A (en) | 1984-02-03 | 1986-01-28 | Tony Durst | 2-Substituted derivatives of podophyllotoxin and etoposide |
| US4609644A (en) | 1984-06-15 | 1986-09-02 | St. Jude Children's Research Hospital | Epipodophyllotoxinquinone glucoside derivatives, method of production and use |
| GB2172594B (en) | 1985-03-22 | 1988-06-08 | Erba Farmitalia | New morpholino derivatives of daunorubicin and doxorubicin |
| GB8508079D0 (en) | 1985-03-28 | 1985-05-01 | Erba Farmitalia | Antitumor anthracyclines |
| US4680338A (en) | 1985-10-17 | 1987-07-14 | Immunomedics, Inc. | Bifunctional linker |
| IL77334A (en) | 1985-12-16 | 1991-04-15 | Univ Bar Ilan | Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor |
| FR2601675B1 (fr) | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2601676B1 (fr) | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Procede de preparation du taxol et du desacetyl-10 taxol |
| US5527524A (en) | 1986-08-18 | 1996-06-18 | The Dow Chemical Company | Dense star polymer conjugates |
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| US4958010A (en) | 1988-02-16 | 1990-09-18 | Bristol-Myers Company | Epipodophyllotoxin glucoside lactam derivatives |
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| US5157049A (en) | 1988-03-07 | 1992-10-20 | The United States Of America As Represented By The Department Of Health & Human Services | Method of treating cancers sensitive to treatment with water soluble derivatives of taxol |
| FR2629818B1 (fr) | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| FR2629819B1 (fr) | 1988-04-06 | 1990-11-16 | Rhone Poulenc Sante | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US4960790A (en) | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
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-
2011
- 2011-07-04 MX MX2013000250A patent/MX2013000250A/es not_active Application Discontinuation
- 2011-07-04 JP JP2013516932A patent/JP2013530993A/ja active Pending
- 2011-07-04 AU AU2011274229A patent/AU2011274229A1/en not_active Abandoned
- 2011-07-04 BR BR112012033295A patent/BR112012033295A2/pt not_active IP Right Cessation
- 2011-07-04 CN CN2011800412044A patent/CN103080125A/zh active Pending
- 2011-07-04 RU RU2013103763/10A patent/RU2013103763A/ru not_active Application Discontinuation
- 2011-07-04 EP EP11800042.1A patent/EP2588490B1/en not_active Not-in-force
- 2011-07-04 CA CA2803646A patent/CA2803646A1/en not_active Abandoned
- 2011-07-04 WO PCT/CA2011/050408 patent/WO2012000118A1/en not_active Ceased
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2015
- 2015-10-23 US US14/921,584 patent/US20160263236A1/en not_active Abandoned
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2017
- 2017-02-22 US US15/439,526 patent/US20180015180A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR112012033295A2 (pt) | 2016-10-11 |
| WO2012000118A1 (en) | 2012-01-05 |
| EP2588490B1 (en) | 2017-02-22 |
| US20160263236A1 (en) | 2016-09-15 |
| CN103080125A (zh) | 2013-05-01 |
| CA2803646A1 (en) | 2012-01-05 |
| EP2588490A1 (en) | 2013-05-08 |
| RU2013103763A (ru) | 2014-08-10 |
| AU2011274229A1 (en) | 2013-01-10 |
| EP2588490A4 (en) | 2013-11-13 |
| US20180015180A1 (en) | 2018-01-18 |
| JP2013530993A (ja) | 2013-08-01 |
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