MX2012003394A - Analogos de la nicotinamida de o-bencilo como moduladores alostéricos positivos del mglur5. - Google Patents

Analogos de la nicotinamida de o-bencilo como moduladores alostéricos positivos del mglur5.

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Publication number
MX2012003394A
MX2012003394A MX2012003394A MX2012003394A MX2012003394A MX 2012003394 A MX2012003394 A MX 2012003394A MX 2012003394 A MX2012003394 A MX 2012003394A MX 2012003394 A MX2012003394 A MX 2012003394A MX 2012003394 A MX2012003394 A MX 2012003394A
Authority
MX
Mexico
Prior art keywords
positive allosteric
allosteric modulators
compounds
nicotinamide analogs
benzyl
Prior art date
Application number
MX2012003394A
Other languages
English (en)
Spanish (es)
Inventor
Richard Williams
P Jeffrey Conn
Craig W Lindsley
Charles David Weaver
Shaun R Stauffer
Gregor James Macdonald
Jose Manuel Bartolome-Nebreda
Ya Zhou
Original Assignee
Univ Vanderbilt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vanderbilt filed Critical Univ Vanderbilt
Publication of MX2012003394A publication Critical patent/MX2012003394A/es

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  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
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  • Endocrinology (AREA)
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MX2012003394A 2009-09-21 2010-09-21 Analogos de la nicotinamida de o-bencilo como moduladores alostéricos positivos del mglur5. MX2012003394A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24441709P 2009-09-21 2009-09-21
PCT/US2010/049697 WO2011035324A1 (en) 2009-09-21 2010-09-21 O-benzyl nicotinamide analogs as mglur5 positive allosteric modulators

Publications (1)

Publication Number Publication Date
MX2012003394A true MX2012003394A (es) 2012-08-15

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ID=43759065

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MX2012003394A MX2012003394A (es) 2009-09-21 2010-09-21 Analogos de la nicotinamida de o-bencilo como moduladores alostéricos positivos del mglur5.

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Country Link
US (1) US20110183980A1 (enExample)
EP (1) EP2482657A4 (enExample)
JP (1) JP2013505297A (enExample)
CN (1) CN102638979A (enExample)
AU (1) AU2010295288A1 (enExample)
BR (1) BR112012006330A2 (enExample)
CA (1) CA2774981A1 (enExample)
IL (1) IL218772A0 (enExample)
IN (1) IN2012DN03322A (enExample)
MX (1) MX2012003394A (enExample)
RU (1) RU2012116124A (enExample)
WO (1) WO2011035324A1 (enExample)

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RU2542100C1 (ru) * 2013-12-24 2015-02-20 Федеральное государственное бюджетное учреждение науки Институт химии растворов им. Г.А. Крестова Российской Академии Наук (ИХС РАН) Сокристаллическая форма теофиллина с дифлунисалом или диклофенаком
TWI713497B (zh) 2015-02-26 2020-12-21 南韓商愛思開生物製藥股份有限公司 咪唑并嘧啶及咪唑并三衍生物及包含該衍生物之醫藥組成物
TW202116754A (zh) 2019-07-11 2021-05-01 美商Ｅ 斯蓋普生物股份有限公司 作為ｌｒｒｋ２抑制劑之吲唑及氮雜吲唑
WO2026072192A1 (en) 2024-09-27 2026-04-02 Alto Neuroscience, Inc. Effective treatment of depression in patients having poor cognition or impaired learning and/or memory with a mglur5 positive allosteric modulator

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EP2482657A1 (en) 2012-08-08
JP2013505297A (ja) 2013-02-14
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BR112012006330A2 (pt) 2017-07-04
US20110183980A1 (en) 2011-07-28
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