MX2011012073A - Lactoferrina y salud y desarrollo cerebral en infantes. - Google Patents
Lactoferrina y salud y desarrollo cerebral en infantes.Info
- Publication number
- MX2011012073A MX2011012073A MX2011012073A MX2011012073A MX2011012073A MX 2011012073 A MX2011012073 A MX 2011012073A MX 2011012073 A MX2011012073 A MX 2011012073A MX 2011012073 A MX2011012073 A MX 2011012073A MX 2011012073 A MX2011012073 A MX 2011012073A
- Authority
- MX
- Mexico
- Prior art keywords
- development
- lactoferrin
- infants
- brain health
- brain
- Prior art date
Links
- 230000004641 brain development Effects 0.000 title abstract 3
- 230000036995 brain health Effects 0.000 title abstract 2
- 102000010445 Lactoferrin Human genes 0.000 title 1
- 108010063045 Lactoferrin Proteins 0.000 title 1
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 title 1
- 229940078795 lactoferrin Drugs 0.000 title 1
- 235000021242 lactoferrin Nutrition 0.000 title 1
- 230000003111 delayed effect Effects 0.000 abstract 2
- 230000003931 cognitive performance Effects 0.000 abstract 1
- 230000018109 developmental process Effects 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/02—Making cheese curd
- A23C19/05—Treating milk before coagulation; Separating whey from curd
- A23C19/053—Enrichment of milk with whey, whey components, substances recovered from separated whey, isolated or concentrated proteins from milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/1526—Amino acids; Peptides; Protein hydrolysates; Nucleic acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
- A23J1/205—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey from whey, e.g. lactalbumine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/20—Milk; Whey; Colostrum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Pediatric Medicine (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere de manera general al campo de desarrollo cerebral y la salud cerebral. Una modalidad de la presente invención se refiere a una composición que puede ser utilizada para el tratamiento o prevención de un desarrollo cerebral retardado y/o un desarrollo cerebral retardado del sistema nervioso. Asimismo se puede incrementar el desempeño cognitivo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09159966A EP2251030A1 (en) | 2009-05-12 | 2009-05-12 | Lactoferrin and brain health and development in infants |
PCT/EP2010/056237 WO2010130643A1 (en) | 2009-05-12 | 2010-05-07 | Lactoferrin and brain health and development in infants |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2011012073A true MX2011012073A (es) | 2012-02-23 |
MX343325B MX343325B (es) | 2016-11-01 |
Family
ID=41119265
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011012073A MX343325B (es) | 2009-05-12 | 2010-05-07 | Lactoferrina y salud y desarrollo cerebral en infantes. |
Country Status (13)
Country | Link |
---|---|
US (1) | US8524658B2 (es) |
EP (2) | EP2251030A1 (es) |
JP (1) | JP2012526746A (es) |
CN (2) | CN105435214B (es) |
BR (1) | BRPI1012211A2 (es) |
CA (1) | CA2761480A1 (es) |
ES (1) | ES2715282T3 (es) |
MX (1) | MX343325B (es) |
MY (1) | MY183291A (es) |
RU (2) | RU2568596C2 (es) |
TW (1) | TW201106966A (es) |
WO (1) | WO2010130643A1 (es) |
ZA (1) | ZA201109089B (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8498729B2 (en) | 2008-08-29 | 2013-07-30 | Smp Logic Systems Llc | Manufacturing execution system for use in manufacturing baby formula |
EP2251031A1 (en) * | 2009-05-12 | 2010-11-17 | Nestec S.A. | Lactoferrin and neuronal health and development in the infant gut |
EP2251032A1 (en) * | 2009-05-12 | 2010-11-17 | Nestec S.A. | Lactoferrin and brain health and protection in adults |
US8968722B2 (en) | 2010-12-29 | 2015-03-03 | Mead Johnson Nutrition Company | Milk-based nutritional compositions containing lactoferrin and uses thereof |
JP2014516589A (ja) | 2011-06-20 | 2014-07-17 | エイチ.ジェイ.ハインツ カンパニー | プロバイオティック組成物及び方法(probioticcompositionandmethods) |
MY170185A (en) | 2011-10-18 | 2019-07-09 | Nestle Sa | Composition for use in brain growth and/or cognitive and/or psychomotor development |
PT2594282E (pt) * | 2011-11-21 | 2014-09-26 | Nestec Sa | Lactoferrina e a matéria branca |
EP2609814A1 (en) * | 2011-12-30 | 2013-07-03 | Nestec S.A. | Lactobacillus reuteri DSM 17938 for the development of cognitive function |
RU2517162C2 (ru) * | 2012-09-24 | 2014-05-27 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский институт акушерства и педиатрии" Министерства здравоохранения и социального развития Российской Федерации | Способ профилактики перинатального поражения центральной нервной системы новорожденных детей |
ITMI20122152A1 (it) | 2012-12-17 | 2014-06-18 | Progine Farmaceutici S R L | Composizione per uso topico. |
AU2013364172B2 (en) * | 2012-12-18 | 2016-12-08 | Mjn U.S. Holdings Llc | Milk-based nutritional compositions containing lactoferrin and uses thereof |
MX2013003636A (es) * | 2013-03-27 | 2014-09-29 | Palsgaard Ind De Mexico S De R L De C V | Complemento alimenticio para personas con trisomia 21, transtorno del espectro autista y/o transtorno por deficit de atencion con o sin hiperactividad. |
US9241923B2 (en) * | 2013-07-16 | 2016-01-26 | Mead Johnson Nutrition Company | Methods for promoting neuronal development and/or health |
US9226914B2 (en) | 2013-07-16 | 2016-01-05 | Mead Johnson Nutrition Company | Methods for promoting neuronal development and/or health |
US9609888B2 (en) | 2013-07-31 | 2017-04-04 | Mead Johnson Nutrition Company | Nutritional compositions containing synergistic combination and uses thereof |
US10709770B2 (en) | 2013-07-31 | 2020-07-14 | Mead Johnson Nutrition Company | Nutritional compositions containing a prebiotic and lactoferrin and uses thereof |
CN105492018A (zh) * | 2013-09-02 | 2016-04-13 | 雀巢产品技术援助有限公司 | 乳铁蛋白和儿童的记忆和学习速度 |
AU2014314537B2 (en) * | 2013-09-02 | 2019-08-15 | Société des Produits Nestlé S.A. | Lactoferrin and memory and learning speed in children |
EP3079485B2 (en) * | 2013-12-13 | 2022-03-30 | Société des Produits Nestlé S.A. | Use of a modified sweet whey and a modified sweet whey containing infant formula for promoting the postnatal development of the infant central nervous system and related cognitive functions |
US20150305385A1 (en) * | 2014-04-25 | 2015-10-29 | Mead Johnson Nutrition Company | Pediatric nutritional composition with human milk oligosaccahrides, prebiotics and probiotics |
EP2992894A1 (en) | 2014-09-05 | 2016-03-09 | Progine Farmaceutici Srl | Vaginal formulations for preventing and treating vaginal and cervico-vaginal infections |
PL235821B1 (pl) * | 2014-11-04 | 2020-11-02 | Geo Poland Spolka Z Ograniczona Odpowiedzialnoscia | Wysokoprolinowy kompleks peptydowy do zastosowania w profilaktyce i wspomaganiu leczenia zaburzeń i stanów wymagających podwyższania i/lub modulacji poziomu neurotropowego czynnika pochodzenia mózgowego jako oznaczonego w osoczu krwi biomarkera i zawierający go preparat |
WO2016073132A1 (en) * | 2014-11-07 | 2016-05-12 | Mjn U.S. Holdings Llc | Nutritional compositions containing a prebiotic and lactoferrin and uses thereof |
US10582714B2 (en) | 2015-07-10 | 2020-03-10 | Mead Johnson Nutrition Company | Nutritional compositions and methods for promoting cognitive development |
US10617701B2 (en) | 2015-07-10 | 2020-04-14 | Mead Johnson Nutrition Company | Nutritional compositions containing phosphatidylethanolamine, sphingomyelin and docosahexaenoic acid |
US11197917B2 (en) * | 2017-12-01 | 2021-12-14 | ByHeart, Inc. | Formulations for nutritional support in subjects in need thereof |
CN109007037B (zh) * | 2018-10-16 | 2022-02-18 | 北京斯利安药业有限公司 | 一种增强婴幼儿免疫力的组合物及其产品与应用 |
CN112493494A (zh) * | 2019-09-16 | 2021-03-16 | 谢驰南 | 含有乳铁蛋白和唾液酸的组合物及其制备方法和用途 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2000A (en) * | 1841-03-12 | Improvement in the manufacture of starch | ||
US7000A (en) * | 1850-01-08 | Smut-machine | ||
EP0322589B1 (fr) | 1987-12-23 | 1993-01-20 | Societe Des Produits Nestle S.A. | Procédé de préparation d'un hydrolysat de protéines de lactosérum et d'un aliment hypoallergéniques |
JP2660908B2 (ja) * | 1995-02-24 | 1997-10-08 | 森永乳業株式会社 | ビフィズス菌増殖促進性及び生残性が良好なヨーグルト |
WO1997014437A1 (en) * | 1995-10-17 | 1997-04-24 | The Regents Of The University Of California | Methods of reducing apolipoprotein e4-induced inhibition of neuron remodeling |
EP0880902A1 (fr) | 1997-05-27 | 1998-12-02 | Nestlé Produkte AG | Procédé de traitement d'une matiére première lactosérique |
US6489375B2 (en) * | 1998-07-07 | 2002-12-03 | Sun Chemical Corporation | Low VOC cationic curable lithographic printing inks |
US6258383B1 (en) * | 1998-08-14 | 2001-07-10 | Lactoferrin Products Company | Dietary supplement combining colostrum and lactoferrin in a mucosal delivery format |
RU2275041C2 (ru) | 1999-04-29 | 2006-04-27 | Сосьете Де Продюи Нестле С.А. | Состав молочной смеси, способ его получения и молочная смесь, содержащая его (варианты) |
AU2003218623B2 (en) * | 2002-03-07 | 2008-01-17 | Upfront Chromatography A/S | A process of isolating lactoferrin |
JP4452569B2 (ja) * | 2004-06-29 | 2010-04-21 | 有限会社フードデザイン健康研究所 | 桃の花及びラクトフェリンを主成分とする食品 |
US20100215631A1 (en) * | 2006-06-14 | 2010-08-26 | Anita Hartog | Anti-inflammatory composition comprising glycine and lactoferrin and the use thereof |
JPWO2007145220A1 (ja) | 2006-06-14 | 2009-11-05 | パナソニック株式会社 | 書き換え可能な回路を備える装置、更新システム、更新方法、更新プログラム、及び集積回路 |
US20080003330A1 (en) * | 2006-06-30 | 2008-01-03 | Ricardo Rueda | Infant formulas for early brain development |
ITRM20060434A1 (it) * | 2006-08-07 | 2008-02-08 | Pietro Raimondi | Prodotto da somministrare all organismo umano per isuoi effetti protettivi e curativi a base di latte di bufala autorricchito di lattoferrina oppure di lattoferrina tal quale ottenuto attraverso processi separativi di membrana |
CN101279866B (zh) | 2007-12-05 | 2011-01-05 | 朱庆然 | 大颗粒尿素或颗粒复合肥硫胞衣智能膜制备方法 |
CN101278688A (zh) * | 2008-05-22 | 2008-10-08 | 澳大利亚迪唯恩乳业有限公司 | 婴幼儿营养免疫配方奶粉及其生产方法 |
-
2009
- 2009-05-12 EP EP09159966A patent/EP2251030A1/en not_active Withdrawn
-
2010
- 2010-05-07 ES ES10718172T patent/ES2715282T3/es active Active
- 2010-05-07 CA CA2761480A patent/CA2761480A1/en not_active Abandoned
- 2010-05-07 CN CN201510968372.8A patent/CN105435214B/zh active Active
- 2010-05-07 MX MX2011012073A patent/MX343325B/es active IP Right Grant
- 2010-05-07 RU RU2011150194/15A patent/RU2568596C2/ru active
- 2010-05-07 WO PCT/EP2010/056237 patent/WO2010130643A1/en active Application Filing
- 2010-05-07 US US13/319,661 patent/US8524658B2/en active Active
- 2010-05-07 MY MYPI2011005403A patent/MY183291A/en unknown
- 2010-05-07 JP JP2012510225A patent/JP2012526746A/ja active Pending
- 2010-05-07 BR BRPI1012211A patent/BRPI1012211A2/pt not_active IP Right Cessation
- 2010-05-07 CN CN201080031300.6A patent/CN102458450B/zh active Active
- 2010-05-07 EP EP10718172.9A patent/EP2429572B1/en active Active
- 2010-05-07 RU RU2015141812A patent/RU2688671C2/ru active
- 2010-05-12 TW TW099115153A patent/TW201106966A/zh unknown
-
2011
- 2011-12-09 ZA ZA2011/09089A patent/ZA201109089B/en unknown
Also Published As
Publication number | Publication date |
---|---|
TW201106966A (en) | 2011-03-01 |
EP2429572B1 (en) | 2018-12-19 |
ZA201109089B (en) | 2013-07-31 |
EP2251030A1 (en) | 2010-11-17 |
ES2715282T3 (es) | 2019-06-03 |
RU2568596C2 (ru) | 2015-11-20 |
CN105435214B (zh) | 2018-12-14 |
RU2015141812A (ru) | 2018-12-28 |
CA2761480A1 (en) | 2010-11-18 |
EP2429572A1 (en) | 2012-03-21 |
CN102458450A (zh) | 2012-05-16 |
JP2012526746A (ja) | 2012-11-01 |
CN105435214A (zh) | 2016-03-30 |
CN102458450B (zh) | 2016-01-13 |
BRPI1012211A2 (pt) | 2016-04-05 |
MY183291A (en) | 2021-02-18 |
WO2010130643A1 (en) | 2010-11-18 |
RU2015141812A3 (es) | 2019-03-26 |
MX343325B (es) | 2016-11-01 |
US8524658B2 (en) | 2013-09-03 |
RU2011150194A (ru) | 2013-06-20 |
RU2688671C2 (ru) | 2019-05-22 |
US20120184484A1 (en) | 2012-07-19 |
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