MX2011003846A - Inmunonanoterapeuticos de nicotina. - Google Patents

Inmunonanoterapeuticos de nicotina.

Info

Publication number
MX2011003846A
MX2011003846A MX2011003846A MX2011003846A MX2011003846A MX 2011003846 A MX2011003846 A MX 2011003846A MX 2011003846 A MX2011003846 A MX 2011003846A MX 2011003846 A MX2011003846 A MX 2011003846A MX 2011003846 A MX2011003846 A MX 2011003846A
Authority
MX
Mexico
Prior art keywords
nanocarriers
provides
nicotine
cells
present
Prior art date
Application number
MX2011003846A
Other languages
English (en)
Other versions
MX336721B (es
Inventor
Omid C Farokhzad
Pamela Basto
Matteo Iannacone
Frank Alexis
Elliott Ashley Moseman
Ulrich Von Andrian
Jinjun Shi
Robert Langer
Elena Tonti
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2008/011932 external-priority patent/WO2009051837A2/en
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of MX2011003846A publication Critical patent/MX2011003846A/es
Publication of MX336721B publication Critical patent/MX336721B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4612—B-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/463—Cellular immunotherapy characterised by recombinant expression
    • A61K39/4632—T-cell receptors [TCR]; antibody T-cell receptor constructs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/464838—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule

Abstract

La presente invención proporciona composiciones y sistemas para el suministro de nanoportadores a células del sistema inmune. La invención proporciona nanoportadores capaces de estimular una respuesta inmune en las células T y/o en las células B. La, invención proporciona nanoportadores que comprenden una superficie inmunocaracterística que tiene una pluralidad de porciones de nicotina. La invención proporciona composiciones farmacéuticas que comprenden lo nanoportadores. La presente invención proporciona métodos para diseñar, manufacturar y usar los nanoportadores y composiciones farmacéuticas de los mismos. Por ejemplo, la presente invención describe nanoportadores capaces de inducir una respuesta inmune y la producción de anticuerpos antinicotina.
MX2011003846A 2008-10-12 2009-10-09 Inmunonanoterapeuticos de nicotina. MX336721B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2008/011932 WO2009051837A2 (en) 2007-10-12 2008-10-12 Vaccine nanotechnology
US12/428,388 US8591905B2 (en) 2008-10-12 2009-04-22 Nicotine immunonanotherapeutics
PCT/US2009/060236 WO2010042866A1 (en) 2008-10-12 2009-10-09 Nicotine immunonanotherapeutics

Publications (2)

Publication Number Publication Date
MX2011003846A true MX2011003846A (es) 2011-09-27
MX336721B MX336721B (es) 2016-01-28

Family

ID=42099036

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011003846A MX336721B (es) 2008-10-12 2009-10-09 Inmunonanoterapeuticos de nicotina.

Country Status (12)

Country Link
US (2) US8591905B2 (es)
EP (1) EP2346528B1 (es)
JP (1) JP5854837B2 (es)
KR (1) KR20110074903A (es)
CN (1) CN102245200A (es)
AU (1) AU2009303334B2 (es)
BR (1) BRPI0920282A2 (es)
CA (1) CA2740248C (es)
IL (1) IL212244A (es)
MX (1) MX336721B (es)
RU (1) RU2487712C2 (es)
WO (1) WO2010042866A1 (es)

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