MX2011002928A - Anticuerpos anti-notch2 y metodos de uso. - Google Patents
Anticuerpos anti-notch2 y metodos de uso.Info
- Publication number
- MX2011002928A MX2011002928A MX2011002928A MX2011002928A MX2011002928A MX 2011002928 A MX2011002928 A MX 2011002928A MX 2011002928 A MX2011002928 A MX 2011002928A MX 2011002928 A MX2011002928 A MX 2011002928A MX 2011002928 A MX2011002928 A MX 2011002928A
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- antibody
- seq
- amino acid
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- hvr
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10191708P | 2008-10-01 | 2008-10-01 | |
| PCT/US2009/059028 WO2010039832A1 (en) | 2008-10-01 | 2009-09-30 | Anti-notch2 antibodies and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2011002928A true MX2011002928A (es) | 2011-04-11 |
Family
ID=41349057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011002928A MX2011002928A (es) | 2008-10-01 | 2009-09-30 | Anticuerpos anti-notch2 y metodos de uso. |
Country Status (18)
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|---|---|
| US (5) | US8404239B2 (OSRAM) |
| EP (1) | EP2334331B1 (OSRAM) |
| JP (2) | JP5710487B2 (OSRAM) |
| KR (1) | KR101712214B1 (OSRAM) |
| CN (1) | CN102170909B (OSRAM) |
| AR (1) | AR073717A1 (OSRAM) |
| AU (1) | AU2009298569A1 (OSRAM) |
| BR (1) | BRPI0913827A2 (OSRAM) |
| CA (1) | CA2736429A1 (OSRAM) |
| CL (1) | CL2011000711A1 (OSRAM) |
| ES (1) | ES2541726T3 (OSRAM) |
| IL (1) | IL211623A0 (OSRAM) |
| MX (1) | MX2011002928A (OSRAM) |
| PE (1) | PE20120080A1 (OSRAM) |
| RU (1) | RU2580029C2 (OSRAM) |
| TW (1) | TW201018484A (OSRAM) |
| WO (1) | WO2010039832A1 (OSRAM) |
| ZA (1) | ZA201101651B (OSRAM) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009539403A (ja) | 2006-06-13 | 2009-11-19 | オンコメッド ファーマシューティカルズ インコーポレイテッド | 癌を診断および処置するための組成物および方法 |
| US8088617B2 (en) | 2007-01-24 | 2012-01-03 | Oncomed Pharmaceuticals, Inc. | Antibodies that bind the glutamate ligand binding region of Notch1 |
| US9132189B2 (en) | 2008-07-08 | 2015-09-15 | Oncomed Pharmaceuticals, Inc. | Notch1 binding agents and methods of use thereof |
| CA2729306C (en) | 2008-07-08 | 2015-08-18 | Oncomed Pharmaceuticals, Inc. | Notch-binding agents and antagonists and methods of use thereof |
| PE20120080A1 (es) * | 2008-10-01 | 2012-02-17 | Genentech Inc | Anticuerpos anti-notch2 y metodos de uso |
| US8906649B2 (en) | 2010-09-27 | 2014-12-09 | Janssen Biotech, Inc. | Antibodies binding human collagen II |
| JP6126991B2 (ja) * | 2010-09-27 | 2017-05-10 | ヤンセン バイオテツク，インコーポレーテツド | ヒトｉｉ型コラーゲンに結合する抗体 |
| US20130089562A1 (en) | 2011-10-05 | 2013-04-11 | Genenthech, Inc. | Methods of treating liver conditions using notch2 antagonists |
| EP2849785A4 (en) * | 2012-05-16 | 2015-12-16 | Oncomed Pharm Inc | METHOD FOR THE TREATMENT OF CANCER WITH NOTCH2 / 3 ANTIBODIES |
| MX357675B (es) | 2012-08-13 | 2018-07-18 | Genentech Inc | Anticuerpos anti-jagged y métodos de uso. |
| WO2014141064A1 (en) | 2013-03-13 | 2014-09-18 | Novartis Ag | Notch2 binding molecules for treating respiratory diseases |
| MX2015011444A (es) * | 2013-03-15 | 2015-12-16 | Genentech Inc | Composiciones y metodos para el diagnostico y tratamiento del cancer hepatico. |
| CA2936565C (en) | 2014-02-12 | 2020-08-11 | Genentech, Inc. | Anti-jagged1 antibodies and methods of use |
| BR112017000130A2 (pt) | 2014-07-11 | 2018-01-09 | Genentech Inc | método para atenuar a toxicidade associada à inibição da via de notch e método de tratamento do câncer |
| US10716829B2 (en) * | 2015-09-26 | 2020-07-21 | National Health Research Institutes | Method and composition for treatment of hair loss |
| GB201521447D0 (en) | 2015-12-04 | 2016-01-20 | Ucb Biopharma Sprl | De novo antibody design |
| US10858443B2 (en) | 2017-05-31 | 2020-12-08 | Trustees Of Boston University | Synthetic notch protein for modulating gene expression |
| IL299799A (en) * | 2020-07-17 | 2023-03-01 | Genentech Inc | Anti-NOTCH2 antibodies and methods of use |
| CN121057747A (zh) * | 2023-04-18 | 2025-12-02 | 上海洛启生物医药技术有限公司 | 抗Notch2纳米抗体及其应用 |
| CN120441700A (zh) * | 2023-11-21 | 2025-08-08 | 兰州大学第二医院 | 一种抗人notch2单链抗体、编码基因、试剂盒及其用途 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
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| PE20120080A1 (es) * | 2008-10-01 | 2012-02-17 | Genentech Inc | Anticuerpos anti-notch2 y metodos de uso |
| RU2011151287A (ru) * | 2009-06-18 | 2013-07-27 | Пфайзер Инк. | АНТИ Notch-1 АНТИТЕЛА |
-
2009
- 2009-09-30 PE PE2011000807A patent/PE20120080A1/es not_active Application Discontinuation
- 2009-09-30 CA CA 2736429 patent/CA2736429A1/en not_active Abandoned
- 2009-09-30 EP EP20090793181 patent/EP2334331B1/en active Active
- 2009-09-30 JP JP2011530173A patent/JP5710487B2/ja active Active
- 2009-09-30 ES ES09793181.0T patent/ES2541726T3/es active Active
- 2009-09-30 WO PCT/US2009/059028 patent/WO2010039832A1/en not_active Ceased
- 2009-09-30 AU AU2009298569A patent/AU2009298569A1/en not_active Abandoned
- 2009-09-30 AR ARP090103776 patent/AR073717A1/es unknown
- 2009-09-30 TW TW98133312A patent/TW201018484A/zh unknown
- 2009-09-30 RU RU2011117237/10A patent/RU2580029C2/ru not_active IP Right Cessation
- 2009-09-30 US US12/570,267 patent/US8404239B2/en active Active
- 2009-09-30 CN CN200980139202.1A patent/CN102170909B/zh active Active
- 2009-09-30 MX MX2011002928A patent/MX2011002928A/es active IP Right Grant
- 2009-09-30 KR KR1020117007489A patent/KR101712214B1/ko not_active Expired - Fee Related
- 2009-09-30 BR BRPI0913827-7A patent/BRPI0913827A2/pt not_active IP Right Cessation
-
2011
- 2011-03-03 ZA ZA2011/01651A patent/ZA201101651B/en unknown
- 2011-03-08 IL IL211623A patent/IL211623A0/en unknown
- 2011-03-31 CL CL2011000711A patent/CL2011000711A1/es unknown
-
2013
- 2013-02-22 US US13/773,843 patent/US20140037643A1/en not_active Abandoned
- 2013-10-11 US US14/051,699 patent/US20140314782A1/en not_active Abandoned
-
2014
- 2014-06-06 US US14/298,488 patent/US20170204175A9/en not_active Abandoned
-
2015
- 2015-03-04 JP JP2015042089A patent/JP2015145379A/ja active Pending
-
2017
- 2017-07-21 US US15/656,967 patent/US20180057589A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0913827A2 (pt) | 2020-12-29 |
| US20180057589A1 (en) | 2018-03-01 |
| RU2580029C2 (ru) | 2016-04-10 |
| KR101712214B1 (ko) | 2017-03-03 |
| PE20120080A1 (es) | 2012-02-17 |
| AU2009298569A1 (en) | 2010-04-08 |
| EP2334331B1 (en) | 2015-04-29 |
| TW201018484A (en) | 2010-05-16 |
| US20140314782A1 (en) | 2014-10-23 |
| RU2011117237A (ru) | 2012-11-10 |
| CA2736429A1 (en) | 2010-04-08 |
| CL2011000711A1 (es) | 2012-07-20 |
| KR20110061600A (ko) | 2011-06-09 |
| ES2541726T3 (es) | 2015-07-23 |
| ZA201101651B (en) | 2012-06-27 |
| CN102170909B (zh) | 2015-11-25 |
| US20150104461A1 (en) | 2015-04-16 |
| US20140037643A1 (en) | 2014-02-06 |
| CN102170909A (zh) | 2011-08-31 |
| JP2015145379A (ja) | 2015-08-13 |
| JP5710487B2 (ja) | 2015-04-30 |
| EP2334331A1 (en) | 2011-06-22 |
| AR073717A1 (es) | 2010-11-24 |
| IL211623A0 (en) | 2011-05-31 |
| US8404239B2 (en) | 2013-03-26 |
| US20170204175A9 (en) | 2017-07-20 |
| WO2010039832A1 (en) | 2010-04-08 |
| US20100080808A1 (en) | 2010-04-01 |
| JP2012504634A (ja) | 2012-02-23 |
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