MX2010011503A - Procedimiento para prevenir el desarrollo de artritis reumatoide en sujetos con artritis indiferenciada. - Google Patents
Procedimiento para prevenir el desarrollo de artritis reumatoide en sujetos con artritis indiferenciada.Info
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- MX2010011503A MX2010011503A MX2010011503A MX2010011503A MX2010011503A MX 2010011503 A MX2010011503 A MX 2010011503A MX 2010011503 A MX2010011503 A MX 2010011503A MX 2010011503 A MX2010011503 A MX 2010011503A MX 2010011503 A MX2010011503 A MX 2010011503A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- A—HUMAN NECESSITIES
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
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- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Molecular Biology (AREA)
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- Biophysics (AREA)
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- Epidemiology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5033608P | 2008-05-05 | 2008-05-05 | |
| US12/387,359 US7915222B2 (en) | 2008-05-05 | 2009-05-01 | Method of preventing the development of rheumatoid arthritis in subjects with undifferentiated arthritis |
| PCT/US2009/042761 WO2009137424A1 (en) | 2008-05-05 | 2009-05-05 | Method of preventing the development of rheumatoid arthritis in subjects with undifferentiated arthritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010011503A true MX2010011503A (es) | 2010-11-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010011503A MX2010011503A (es) | 2008-05-05 | 2009-05-05 | Procedimiento para prevenir el desarrollo de artritis reumatoide en sujetos con artritis indiferenciada. |
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| Country | Link |
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| US (3) | US7915222B2 (OSRAM) |
| EP (2) | EP2891665A1 (OSRAM) |
| JP (1) | JP2011522795A (OSRAM) |
| KR (1) | KR20110014180A (OSRAM) |
| CN (1) | CN102037010A (OSRAM) |
| AR (1) | AR071672A1 (OSRAM) |
| AU (1) | AU2009244448B2 (OSRAM) |
| BR (1) | BRPI0912249A2 (OSRAM) |
| CA (1) | CA2723698C (OSRAM) |
| CL (1) | CL2009001082A1 (OSRAM) |
| DK (1) | DK2279206T3 (OSRAM) |
| EA (1) | EA201001749A1 (OSRAM) |
| ES (1) | ES2539840T3 (OSRAM) |
| HK (1) | HK1208230A1 (OSRAM) |
| HR (1) | HRP20150552T1 (OSRAM) |
| HU (1) | HUE025256T2 (OSRAM) |
| IL (1) | IL208691A (OSRAM) |
| MX (1) | MX2010011503A (OSRAM) |
| NZ (1) | NZ589020A (OSRAM) |
| PL (1) | PL2279206T3 (OSRAM) |
| PT (1) | PT2279206E (OSRAM) |
| SI (1) | SI2279206T1 (OSRAM) |
| TW (2) | TW201444575A (OSRAM) |
| WO (1) | WO2009137424A1 (OSRAM) |
| ZA (1) | ZA201007914B (OSRAM) |
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| US20040022787A1 (en) * | 2000-07-03 | 2004-02-05 | Robert Cohen | Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID |
| US7915222B2 (en) | 2008-05-05 | 2011-03-29 | Bristol-Myers Squibb Company | Method of preventing the development of rheumatoid arthritis in subjects with undifferentiated arthritis |
| RU2014117510A (ru) * | 2011-10-10 | 2015-11-20 | Медиммьюн Лимитед | Лечение ревматоидного артрита |
| US20140006055A1 (en) * | 2012-06-27 | 2014-01-02 | Iagnosis, Inc. | Integrated Medical Evaluation and Record Keeping System |
| WO2014070840A2 (en) * | 2012-10-30 | 2014-05-08 | Emory University | Stimulating bone formation by inhibition of cd28 co-stimulation |
| WO2014151230A2 (en) * | 2013-03-15 | 2014-09-25 | Bristol-Myers Squibb Company | Method of treating granulomatosis with polyangiitis |
| KR20160145789A (ko) * | 2014-04-25 | 2016-12-20 | 브리스톨-마이어스 스큅 컴퍼니 | 초기 ra를 갖는 대상체에서의 무약물 완화를 달성하기 위한 ctla4 화합물의 용도 |
| EP3875477A1 (en) | 2015-04-17 | 2021-09-08 | Alpine Immune Sciences, Inc. | Immunomodulatory proteins with tunable affinities |
| KR102813968B1 (ko) | 2017-10-10 | 2025-05-29 | 알파인 이뮨 사이언시즈, 인코포레이티드 | Ctla-4 변이체 면역조절 단백질 및 이의 용도 |
| US12297253B2 (en) | 2018-01-03 | 2025-05-13 | Alpine Immune Sciences, Inc. | Multi-domain immunomodulatory proteins and methods of use thereof |
| CN110148465B (zh) * | 2019-05-10 | 2023-07-04 | 中山大学孙逸仙纪念医院 | 一种用于分析类风湿性关节炎的系统 |
Family Cites Families (28)
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| US5521288A (en) * | 1990-03-26 | 1996-05-28 | Bristol-Myers Squibb Company | CD28IG fusion protein |
| US7070776B1 (en) * | 1990-03-26 | 2006-07-04 | Bristol-Myers Squibb Company | Methods for blocking binding of CD28 receptor to B7 |
| US5844095A (en) * | 1991-06-27 | 1998-12-01 | Bristol-Myers Squibb Company | CTLA4 Ig fusion proteins |
| US5770197A (en) * | 1991-06-27 | 1998-06-23 | Bristol-Myers Squibb Company | Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules |
| US5851795A (en) * | 1991-06-27 | 1998-12-22 | Bristol-Myers Squibb Company | Soluble CTLA4 molecules and uses thereof |
| US6090914A (en) * | 1991-06-27 | 2000-07-18 | Bristol-Myers Squibb Company | CTLA4/CD28Ig hybrid fusion proteins and uses thereof |
| DE69226871T3 (de) * | 1991-06-27 | 2009-09-24 | Bristol-Myers Squibb Co. | CTL4A-Rezeptor, ihn enthaltenden Fusionsproteine und deren Verwendung |
| WO1994017104A1 (en) * | 1993-01-21 | 1994-08-04 | The University Of Georgia Research Foundation, Inc. | Vaccines and methods for preventing and treating fescue toxicosis in herbivores |
| US5773253A (en) * | 1993-01-22 | 1998-06-30 | Bristol-Myers Squibb Company | MYPPPY variants of CTL A4 and uses thereof |
| US6750334B1 (en) * | 1996-02-02 | 2004-06-15 | Repligen Corporation | CTLA4-immunoglobulin fusion proteins having modified effector functions and uses therefor |
| DE69713499T3 (de) * | 1996-03-20 | 2010-05-06 | Bristol-Myers Squibb Co., Seattle | Verfahren zur inhibierung der immunreaktion durch blockierung der gp39/cd40 und ctla4/cd28/b7 routen und zusammensetzung zu deren verwendung |
| ZA98533B (en) * | 1997-01-31 | 1999-07-22 | Bristol Myers Squibb Co | Soluble CTLA4 mutant molecules and uses thereof. |
| US20030219863A1 (en) * | 1997-01-31 | 2003-11-27 | Bristol-Myers Squibb Company | Soluble CTLA4 mutant molecules and uses thereof |
| US7094874B2 (en) * | 2000-05-26 | 2006-08-22 | Bristol-Myers Squibb Co. | Soluble CTLA4 mutant molecules |
| US20020039577A1 (en) * | 2000-06-09 | 2002-04-04 | Townsend Robert M. | Methods for regulating a lymphocyte-mediated immune response by blocking costimulatory signals and blocking LFA-1 mediated adhesion in lymphocytes |
| US20040022787A1 (en) * | 2000-07-03 | 2004-02-05 | Robert Cohen | Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID |
| RU2287340C2 (ru) * | 2000-07-03 | 2006-11-20 | Бристол-Маерс Сквибб Компани | Способы лечения ревматических заболеваний с применением растворимого ctla4 |
| PL375139A1 (en) * | 2001-01-26 | 2005-11-28 | Emory University | Methods of inducing organ transplant tolerance and correcting hemoglobinopathies |
| HU229680B1 (hu) * | 2001-05-23 | 2014-04-28 | Bristol Myers Squibb Co | Eljárások allogén sziget átültetés védelmére oldható CTLA4 mutáns molekulák alkalmazásával |
| TWI328614B (en) * | 2002-12-23 | 2010-08-11 | Bristol Myers Squibb Co | Product quality enhancement in mammalian cell culture processes for protein production |
| CA2511520A1 (en) * | 2002-12-23 | 2004-07-15 | Bristol-Myers Squibb Company | Mammalian cell culture processes for protein production |
| WO2005016266A2 (en) * | 2003-08-04 | 2005-02-24 | Bristol-Myers Squibb Company | Methods for treating cardiovascular disease using a soluble ctla4 molecule |
| ES2360232T3 (es) | 2005-06-29 | 2011-06-02 | Compumedics Limited | Conjunto sensor con puente conductor. |
| US8702777B2 (en) * | 2005-08-22 | 2014-04-22 | Incept, Llc | Steep-taper flared stents and apparatus and methods for delivering them |
| ES2439641T3 (es) | 2005-12-20 | 2014-01-24 | Bristol-Myers Squibb Company | Composiciones y procedimientos de producción de una composición |
| PE20071063A1 (es) | 2005-12-20 | 2007-10-24 | Bristol Myers Squibb Co | Formulaciones de proteinas estables |
| US7528111B2 (en) * | 2006-05-12 | 2009-05-05 | Bristol-Myers Squibb Company | Method of vaccinating subjects receiving immune modulating therapy |
| US7915222B2 (en) * | 2008-05-05 | 2011-03-29 | Bristol-Myers Squibb Company | Method of preventing the development of rheumatoid arthritis in subjects with undifferentiated arthritis |
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- 2009-05-05 CA CA2723698A patent/CA2723698C/en active Active
- 2009-05-05 HR HRP20150552TT patent/HRP20150552T1/hr unknown
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- 2009-05-05 ES ES09743410.4T patent/ES2539840T3/es active Active
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2010
- 2010-10-13 IL IL208691A patent/IL208691A/en not_active IP Right Cessation
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2011
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2013
- 2013-03-27 US US13/851,166 patent/US9012408B2/en active Active
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