MX2010010015A - Metodo novedoso para la produccion de sulfonilpirroles como inhibidores de hdac. - Google Patents
Metodo novedoso para la produccion de sulfonilpirroles como inhibidores de hdac.Info
- Publication number
- MX2010010015A MX2010010015A MX2010010015A MX2010010015A MX2010010015A MX 2010010015 A MX2010010015 A MX 2010010015A MX 2010010015 A MX2010010015 A MX 2010010015A MX 2010010015 A MX2010010015 A MX 2010010015A MX 2010010015 A MX2010010015 A MX 2010010015A
- Authority
- MX
- Mexico
- Prior art keywords
- formula
- alkyl
- compound
- alkoxy
- group
- Prior art date
Links
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
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Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08004567A EP2100878A1 (en) | 2008-03-12 | 2008-03-12 | Novel method for the production of sulphonylpyrroles as HDAC inhibitors |
| PCT/EP2009/052870 WO2009112529A1 (en) | 2008-03-12 | 2009-03-11 | Novel method for the production of sulphonylpyrroles as hdac inhibitors |
Publications (1)
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| MX2010010015A true MX2010010015A (es) | 2011-04-05 |
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| MX2010010015A MX2010010015A (es) | 2008-03-12 | 2009-03-11 | Metodo novedoso para la produccion de sulfonilpirroles como inhibidores de hdac. |
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|---|---|
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| EP (2) | EP2100878A1 (enExample) |
| JP (1) | JP5530939B2 (enExample) |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2100882A1 (en) * | 2008-03-12 | 2009-09-16 | 4Sc Ag | (E) -N -(2-Amino-phenyl) -3-{1-[4-(1-methyl-1H-pyrazol-4-yl)- benzenesulfonyl]-1H-pyrrol-3-yl} -acrylamide salts |
| WO2017178577A1 (en) | 2016-04-14 | 2017-10-19 | 4Sc Ag | Medical application of resminostat in asian patients |
| TW201912183A (zh) | 2017-08-31 | 2019-04-01 | 德商４Ｓｃ製藥公司 | Hdac抑制劑與抗代謝藥劑組合用於癌症治療 |
Family Cites Families (7)
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| US4960787A (en) | 1989-02-06 | 1990-10-02 | Ciba-Geigy Corporation | Certain pyrrolyl-substituted hydroxamic acid derivatives |
| DE69221290T2 (de) * | 1991-12-10 | 1998-01-15 | Shionogi & Co | Auf aromatischen sulfonamiden basierende hydroxamsäurederivate |
| CA2223154A1 (en) | 1995-06-02 | 1996-12-05 | G.D. Searle & Co. | Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
| US7842820B2 (en) | 2004-03-11 | 2010-11-30 | 4Sc Ag | Sulfonylpyrroles |
| DE602006007558D1 (de) * | 2005-03-15 | 2009-08-13 | 4Sc Ag | N-sulfonylpyrrole und ihre verwendung als histondeacetylaseinhibitoren |
| EA018698B1 (ru) | 2005-09-21 | 2013-10-30 | 4Сц Аг | Сульфонилпирролгидрохлориды как ингибиторы гистондезацетилазы |
| KR101256846B1 (ko) | 2005-09-21 | 2013-04-24 | 4에스체 악티엔게젤샤프트 | Ｈｄａｃ의 억제제로서의 신규한 설포닐피롤 |
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