MX2010004688A - Usos terapeuticos de compuestos que tienen actividad combinada de sert, 5- ht3 y 5-ht1a. - Google Patents
Usos terapeuticos de compuestos que tienen actividad combinada de sert, 5- ht3 y 5-ht1a.Info
- Publication number
- MX2010004688A MX2010004688A MX2010004688A MX2010004688A MX2010004688A MX 2010004688 A MX2010004688 A MX 2010004688A MX 2010004688 A MX2010004688 A MX 2010004688A MX 2010004688 A MX2010004688 A MX 2010004688A MX 2010004688 A MX2010004688 A MX 2010004688A
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- therapeutic uses
- ht1a activity
- sert
- combined
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Nutrition Science (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Se proveen nuevos usos farmacéuticos de 1-[2-(2,4-dimetilfenilsulf anil)fenil]piperazina y de sus sales aceptables para uso farmacéutico.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98771007P | 2007-11-13 | 2007-11-13 | |
DKPA200701607 | 2007-11-13 | ||
US1372207P | 2007-12-14 | 2007-12-14 | |
DKPA200701788 | 2007-12-14 | ||
US9784008P | 2008-09-17 | 2008-09-17 | |
DKPA200801300 | 2008-09-17 | ||
PCT/DK2008/050271 WO2009062517A1 (en) | 2007-11-13 | 2008-11-12 | Therapeutic uses of compounds having combined sert, 5-ht3 and 5-ht1a activity |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010004688A true MX2010004688A (es) | 2010-09-09 |
Family
ID=40170671
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010004688A MX2010004688A (es) | 2007-11-13 | 2008-11-12 | Usos terapeuticos de compuestos que tienen actividad combinada de sert, 5- ht3 y 5-ht1a. |
Country Status (30)
Country | Link |
---|---|
US (5) | US9278096B2 (es) |
EP (3) | EP2431039B1 (es) |
JP (2) | JP5603244B2 (es) |
KR (1) | KR101536023B1 (es) |
CN (1) | CN102014908A (es) |
AR (1) | AR069260A1 (es) |
AT (1) | ATE537829T1 (es) |
AU (1) | AU2008323390B2 (es) |
BR (1) | BRPI0820474B8 (es) |
CA (1) | CA2705163C (es) |
CL (1) | CL2008003363A1 (es) |
CO (1) | CO6270322A2 (es) |
CY (2) | CY1112646T1 (es) |
DK (2) | DK2431039T3 (es) |
EA (1) | EA027783B1 (es) |
ES (2) | ES2379419T5 (es) |
HR (2) | HRP20120144T4 (es) |
HU (1) | HUE029588T2 (es) |
IL (1) | IL205466A (es) |
LT (1) | LT2431039T (es) |
MX (1) | MX2010004688A (es) |
NZ (1) | NZ585247A (es) |
PL (2) | PL2219647T3 (es) |
PT (2) | PT2219647E (es) |
RS (2) | RS52256B2 (es) |
SG (1) | SG10201405001XA (es) |
SI (2) | SI2219647T2 (es) |
TW (1) | TW200932233A (es) |
WO (1) | WO2009062517A1 (es) |
ZA (1) | ZA201003350B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200932233A (en) | 2007-11-13 | 2009-08-01 | Lundbeck & Co As H | Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity |
CA2769872A1 (en) * | 2009-08-24 | 2011-03-03 | H. Lundbeck A/S | New compositions of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]piperazine |
TW201212918A (en) * | 2010-08-23 | 2012-04-01 | Lundbeck & Co As H | Therapeutic uses of 1-[2-(2,4-dimethyl-phenylsulfanyl)phenyl]piperazine |
BR112013018898B1 (pt) * | 2011-01-27 | 2021-10-05 | Neuren Pharmaceuticals Limited | Uso de ácido glicil-l-2-metilprolil-l-glutâmico e análogos do mesmo para o tratamento de transtornos do espectro do autismo |
WO2013012038A1 (ja) | 2011-07-21 | 2013-01-24 | 学校法人名城大学 | うつ病決定方法、セロトニントランスポーター分析キット及び血中ユビキチン化セロトニントランスポーター分析キット |
NZ708595A (en) * | 2012-12-13 | 2019-06-28 | H Lundbeck As | Compositions comprising vortioxetine and donepezil |
JP6323979B2 (ja) * | 2013-01-17 | 2018-05-16 | 学校法人 名城大学 | うつ病マーカー、アッセイ方法、測定方法、うつ病薬のスクリーニング方法及びキット |
WO2014191548A1 (en) * | 2013-05-31 | 2014-12-04 | Lek Pharmaceuticals D.D. | New process for the synthesis of 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine |
EP2878596A1 (en) * | 2013-11-29 | 2015-06-03 | LEK Pharmaceuticals d.d. | Synthesis of vortioxetine via (2-(piperazine-1-yl)phenyl)lithium intermediates |
CA2933733A1 (en) * | 2013-12-20 | 2015-06-25 | Connie Sanchez Morillo | Use of an opioid receptor antagonist with kappa-activity and vortioxetine for treatment of depressive disorder with melancholic features |
CN103788019B (zh) * | 2014-01-22 | 2015-10-07 | 苏州明锐医药科技有限公司 | 沃替西汀的制备方法 |
US9822086B2 (en) | 2014-01-31 | 2017-11-21 | Egis Gyogyszergyar Zrt. | Process for the preparation of vortioxetine salts |
EP2930171A1 (en) * | 2014-04-07 | 2015-10-14 | LEK Pharmaceuticals d.d. | Synthesis of vortioxetine via (2,4-dimethylphenyl)(2-iodophenyl)sulfane intermediate |
CN104119298B (zh) * | 2014-08-13 | 2016-08-24 | 北京蓝贝望生物医药科技股份有限公司 | 氢溴酸沃赛汀或氢溴酸沃替西汀 |
CN104119299B (zh) * | 2014-08-13 | 2016-08-17 | 北京蓝贝望生物医药科技股份有限公司 | 沃赛汀或沃替西汀的氢溴酸盐 |
CN104610195B (zh) * | 2015-01-30 | 2017-06-27 | 上虞京新药业有限公司 | 沃替西汀的天冬氨酸盐或其水合物及其制备方法和用途 |
JO3456B1 (ar) * | 2015-05-13 | 2020-07-05 | H Lundbeck As | فيروتيوكسيتين بيروجلوتامات |
AU2016296205B2 (en) * | 2015-07-17 | 2021-11-11 | Centre Hospitalier Sainte Anne Paris | 5-hydroxytryptamine 1B receptor-stimulating agent for use as a promoter of satellite cells self-renewal and/or differentiation |
SG11201810644TA (en) | 2016-07-01 | 2018-12-28 | H Lundbeck As | Vortioxetine dosing regimes for fast onset of antidepressant effect |
JP2023520016A (ja) | 2020-04-03 | 2023-05-15 | ハー・ルンドベック・アクチエゼルスカベット | 感情鈍麻の予防又は処置のための1-[2-(2,4-ジメチルフェニルスルファニル)-フェニル]ピペラジン |
WO2023036820A1 (en) | 2021-09-10 | 2023-03-16 | H. Lundbeck A/S | Therapeutic uses of 1-[2-(2,4-dimethyl-phenylsulfanyl)phenyl]piperazine |
KR20230148676A (ko) | 2022-04-18 | 2023-10-25 | 영진약품 주식회사 | 라베프라졸 및 탄산수소나트륨을 포함하는 조성물 및 이의 용도 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU163075A (en) * | 1975-07-21 | 1982-05-31 | Science Union & Cie | Process for preparing new phenoxy derivatives |
US5258387A (en) | 1990-08-21 | 1993-11-02 | Hoffmann-La Roche Inc. | Tricyclic pyridone derivatives |
UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
CA2467118A1 (en) * | 2001-12-20 | 2003-07-03 | H. Lundbeck A/S | Aryloxyphenyl and arylsulfanylphenyl derivatives |
US7732463B2 (en) | 2003-04-04 | 2010-06-08 | H. Lundbeck A/S | 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors |
US20060019938A1 (en) | 2003-12-31 | 2006-01-26 | Beer Tomasz M | Estrogen administration for treating male cognitive dysfunction or improving male cognitive function |
RS52205B2 (sr) * | 2006-06-16 | 2021-05-31 | H Lundbeck A/S | 1-[2-(2,4-dimetilfenilsulfanil)-fenil]piperazin kao jedinjenje sa kombinovanom aktivnošću ponovnog uzimanja serotonina, 5-ht3 i 5-ht1a, za tretman kognitivnih oštećenja |
TW200848411A (en) * | 2007-03-20 | 2008-12-16 | Lundbeck & Co As H | Novel therapeutic uses of 1-[2-(2, 4-dimethylphenylsulfanyl)phenyl]-piperazine |
TW200932233A (en) * | 2007-11-13 | 2009-08-01 | Lundbeck & Co As H | Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity |
CA2769872A1 (en) | 2009-08-24 | 2011-03-03 | H. Lundbeck A/S | New compositions of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]piperazine |
-
2008
- 2008-11-03 TW TW097142306A patent/TW200932233A/zh unknown
- 2008-11-11 AR ARP080104919A patent/AR069260A1/es unknown
- 2008-11-12 US US12/741,780 patent/US9278096B2/en active Active
- 2008-11-12 SG SG10201405001XA patent/SG10201405001XA/en unknown
- 2008-11-12 EP EP11193237.2A patent/EP2431039B1/en active Active
- 2008-11-12 SI SI200830548T patent/SI2219647T2/sl unknown
- 2008-11-12 PT PT08850935T patent/PT2219647E/pt unknown
- 2008-11-12 CN CN2008801164637A patent/CN102014908A/zh active Pending
- 2008-11-12 AT AT08850935T patent/ATE537829T1/de active
- 2008-11-12 EP EP08850935.1A patent/EP2219647B2/en active Active
- 2008-11-12 LT LTEP11193237.2T patent/LT2431039T/lt unknown
- 2008-11-12 DK DK11193237.2T patent/DK2431039T3/en active
- 2008-11-12 CA CA2705163A patent/CA2705163C/en active Active
- 2008-11-12 JP JP2010533436A patent/JP5603244B2/ja active Active
- 2008-11-12 EA EA201070598A patent/EA027783B1/ru not_active IP Right Cessation
- 2008-11-12 EP EP16178423.6A patent/EP3115050A1/en not_active Withdrawn
- 2008-11-12 WO PCT/DK2008/050271 patent/WO2009062517A1/en active Application Filing
- 2008-11-12 RS RS20120087A patent/RS52256B2/sr unknown
- 2008-11-12 BR BRPI0820474A patent/BRPI0820474B8/pt active IP Right Grant
- 2008-11-12 ES ES08850935T patent/ES2379419T5/es active Active
- 2008-11-12 RS RS20160756A patent/RS55147B1/sr unknown
- 2008-11-12 AU AU2008323390A patent/AU2008323390B2/en active Active
- 2008-11-12 SI SI200831677A patent/SI2431039T1/sl unknown
- 2008-11-12 KR KR1020107010492A patent/KR101536023B1/ko active IP Right Review Request
- 2008-11-12 PT PT111932372T patent/PT2431039T/pt unknown
- 2008-11-12 PL PL08850935T patent/PL2219647T3/pl unknown
- 2008-11-12 DK DK08850935.1T patent/DK2219647T4/da active
- 2008-11-12 CL CL2008003363A patent/CL2008003363A1/es unknown
- 2008-11-12 MX MX2010004688A patent/MX2010004688A/es active IP Right Grant
- 2008-11-12 HU HUE11193237A patent/HUE029588T2/en unknown
- 2008-11-12 ES ES11193237.2T patent/ES2591110T3/es active Active
- 2008-11-12 NZ NZ585247A patent/NZ585247A/en not_active IP Right Cessation
- 2008-11-12 PL PL11193237.2T patent/PL2431039T3/pl unknown
-
2010
- 2010-04-29 IL IL205466A patent/IL205466A/en active IP Right Grant
- 2010-05-12 ZA ZA2010/03350A patent/ZA201003350B/en unknown
- 2010-05-13 CO CO10057476A patent/CO6270322A2/es not_active Application Discontinuation
-
2012
- 2012-02-14 HR HRP20120144TT patent/HRP20120144T4/hr unknown
- 2012-02-24 CY CY20121100199T patent/CY1112646T1/el unknown
-
2014
- 2014-05-14 JP JP2014100815A patent/JP5841636B2/ja active Active
-
2016
- 2016-02-12 US US15/043,167 patent/US9744166B2/en active Active
- 2016-09-01 HR HRP20161121TT patent/HRP20161121T1/hr unknown
- 2016-09-07 CY CY20161100885T patent/CY1117978T1/el unknown
-
2017
- 2017-07-27 US US15/661,392 patent/US20180161321A1/en not_active Abandoned
-
2020
- 2020-05-12 US US15/930,014 patent/US11628166B2/en active Active
-
2023
- 2023-04-04 US US18/130,749 patent/US20240082239A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2010004688A (es) | Usos terapeuticos de compuestos que tienen actividad combinada de sert, 5- ht3 y 5-ht1a. | |
HRP20120173T1 (en) | 1- ¦[- (2, 4-dimethylphenylsulfanyl) -phenyl]piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment | |
UA97392C2 (ru) | 1-[2-(2,4-диметилфенилсульфанил)фенил]пиперазин как соединение с комбинированной активностью в отношении обратного захвата серотонина, 5-нт3 и 5-нт1a для лечения боли | |
MX2009014208A (es) | Compuestos heterociclicos y usos de los mismos como inhibidores de erk. | |
EA200971046A1 (ru) | Новые соли пиперазина в качестве d/d-антагонистов | |
RS50624B (sr) | Monohidrohloridna so 1-[3-[3-(4-hlorofenil)propoksi]propil]piperidina | |
TN2011000504A1 (en) | Liquid formulations of salts of 1-[2-(2,4- dimethylphenylsulfanyl) phenyl] piperazine | |
GEP20125538B (en) | 2,3-dihydrobenzo(1,4) dioxin-2-ylmethyl derivatives as alpha2c antagonists for use in the treatment of peripheric and central nervous system diseases | |
GEP20135730B (en) | Trans-4-{2-[4-(2,3-dichlorophe-nyl)-piperazin-1-yl]-ethyl}-n,n-dimethylcarbamoyl-cyclohexylamine for treatment of schizophrenia | |
RS54608B1 (en) | CGRP RECEPTOR ANTAGONITY | |
RS53521B1 (en) | PREPARATION AND THERAPY APPLICATIONS (2S, 3R) -N-2 - ((3-pyridinyl) methyl) -1-AZABICYCLO [2.2.2] OCT-3-IL) -3,5-DIFLUOROBENZAMIDE | |
SMT201300108B (it) | Nuove composizioni di 1-Ä2-(2,4-dimetilfenil solfanil)-fenilÜ piperazina | |
NO20082112L (no) | 3-Amino-2-arylpropylazaindoler og deres anvendelse | |
GEP20115222B (en) | New pharmaceutical compounds | |
UA101323C2 (en) | Trans-4-{2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl}-n,n-dimethylcarbamoyl-cyclohexylamine for the treatment of acute mania | |
DE602005010744D1 (de) | Piperazinylpyridinderivate als mittel gegen adipositas | |
TW200732304A (en) | Piperidine derivatives | |
GEP20135805B (en) | 1-(ARYLSULFONYL)-4-(PIPERAZIN-1-YL)-1H-BENZIMIDAZOLES AS δ-HYDROXYTRYPTAMINE-6 LIGANDS | |
NZ600266A (en) | Compound, certain novel forms thereof, pharmaceutical compositions thereof and methods for preparation and use | |
RS54293B1 (en) | PHARMACEUTICAL COMBINATION | |
TW200700390A (en) | Metabolites for nk-1 antagonists for emesis | |
MX349724B (es) | Usos terapeuticos de 1-[2-(2,4-dimetil-fenilsulfanil)fenil]piperaz ina. | |
EA201000611A1 (ru) | 4,4-дизамещенные пиперидины | |
UA101341C2 (ru) | Терапевтические применения соединений, которые имеют комбинированную активность в отношении sert, 5-нт3 и 5-нт1a | |
MY145425A (en) | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
GD | Licence granted | ||
HC | Change of company name or juridical status |