MX2010002716A - Uso de slit, nefrina, efrina o semaforina para el tratamiento de enfermedades de cartilago. - Google Patents
Uso de slit, nefrina, efrina o semaforina para el tratamiento de enfermedades de cartilago.Info
- Publication number
- MX2010002716A MX2010002716A MX2010002716A MX2010002716A MX2010002716A MX 2010002716 A MX2010002716 A MX 2010002716A MX 2010002716 A MX2010002716 A MX 2010002716A MX 2010002716 A MX2010002716 A MX 2010002716A MX 2010002716 A MX2010002716 A MX 2010002716A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- degenerative diseases
- neuroendocrine factors
- polypeptide
- neuroendocrine
- Prior art date
Links
- 208000015122 neurodegenerative disease Diseases 0.000 title abstract 2
- 230000000955 neuroendocrine Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 101700004678 SLIT3 Proteins 0.000 abstract 2
- 102100025490 Slit homolog 1 protein Human genes 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000002940 repellent Effects 0.000 abstract 1
- 239000005871 repellent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Dispersion Chemistry (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07018131A EP2036921A1 (en) | 2007-09-14 | 2007-09-14 | Use of Slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases |
| EP08006810 | 2008-04-03 | ||
| PCT/EP2008/007579 WO2009033715A2 (en) | 2007-09-14 | 2008-09-12 | Neuroendocrine factors for treatment of degenerative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010002716A true MX2010002716A (es) | 2010-07-05 |
Family
ID=40452588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010002716A MX2010002716A (es) | 2007-09-14 | 2008-09-12 | Uso de slit, nefrina, efrina o semaforina para el tratamiento de enfermedades de cartilago. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20110002972A1 (https=) |
| EP (1) | EP2212344B1 (https=) |
| JP (1) | JP2010539123A (https=) |
| KR (1) | KR20100075493A (https=) |
| CN (1) | CN101821283A (https=) |
| AU (1) | AU2008297889A1 (https=) |
| BR (1) | BRPI0816784A8 (https=) |
| CA (1) | CA2699411A1 (https=) |
| MX (1) | MX2010002716A (https=) |
| NZ (1) | NZ583851A (https=) |
| RU (1) | RU2496790C2 (https=) |
| WO (1) | WO2009033715A2 (https=) |
| ZA (1) | ZA201001644B (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1400024B1 (it) * | 2010-05-21 | 2013-05-17 | Uni Politecnica Delle Marche | Uso farmaceutico di semaforine. |
| CN103703021A (zh) * | 2010-12-23 | 2014-04-02 | 赛诺菲 | 用于治疗肝癌的Robo1-Fc融合蛋白 |
| KR101786862B1 (ko) * | 2011-07-04 | 2017-10-18 | 메소블라스트, 아이엔씨. | 류마티즘성 질환을 치료 또는 예방하는 방법 |
| WO2013187730A1 (ko) * | 2012-06-15 | 2013-12-19 | 재단법인 아산사회복지재단 | Slit-Robo 시스템을 이용한 골절 또는 골다공증의 예방 또는 치료용 조성물 |
| ES2442242B1 (es) * | 2012-08-09 | 2014-11-25 | Biotechnology Institute, I Mas D, S.L. | Composición con factores de crecimiento destinada al tratamiento intranasal de una enfermedad neurodegenerativa u otra patología del sistema nervioso central, y su método de fabricación. |
| CN104119448A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| CN104119446A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| CN104119447A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| CN104119445A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| WO2015072527A1 (ja) * | 2013-11-13 | 2015-05-21 | 国立大学法人大阪大学 | ネトリン1含有破骨細胞形成抑制剤 |
| HUE068789T2 (hu) | 2014-03-14 | 2025-01-28 | Univ New York State Res Found | A csontnövekedés és a csontlebontás neurogén szabályozása |
| US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
| WO2019161136A1 (en) * | 2018-02-14 | 2019-08-22 | Cornell University | Slit and bone growth modulation |
| EP3932430A4 (en) * | 2019-02-27 | 2023-02-01 | Daewoong Pharmaceutical Co., Ltd. | ALBUMIN-RELATED COMPOSITION COMPRISING LRRD2 OF THE SLIT3 PROTEIN FOR THE PREVENTION OR TREATMENT OF BONE DISEASES |
| WO2021050970A1 (en) * | 2019-09-13 | 2021-03-18 | Rutgers, The State University Of New Jersey | Aav-compatible laminin-linker polymerization proteins |
| CN110694051B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎注射剂中的应用 |
| CN110841057B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎巴布膏剂中的应用 |
| CN110684805B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 神经导向因子Sema基因重组慢病毒载体在制备治疗骨关节炎药物中的应用 |
| CN110721308B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种用于治疗骨关节炎的药物复方制剂及其制备方法 |
| CN110772632B (zh) * | 2019-11-19 | 2023-08-11 | 四川大学华西医院 | 神经导向因子semaphorin 3a在制备治疗骨关节炎药物中的用途 |
| CN110711244B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎搽剂中的应用 |
| WO2023008337A1 (ja) * | 2021-07-26 | 2023-02-02 | ピューロテックバイオ株式会社 | 宿主因子lipgをターゲットとした抗b型肝炎ウイルス剤 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2700117B1 (fr) * | 1993-01-07 | 1995-02-03 | Rhone Poulenc Rorer Sa | Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens. |
| JPH1116490A (ja) * | 1997-06-26 | 1999-01-22 | Kyocera Corp | プラズマディスプレイパネル用隔壁の製造方法及びプラズマディスプレイパネル用基板 |
| US20030032057A1 (en) * | 1997-08-26 | 2003-02-13 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WO1999023219A1 (en) * | 1997-10-31 | 1999-05-14 | Osiris Therapeutics, Inc. | Human slit polypeptide and polynucleotides encoding same |
| JPH11164690A (ja) * | 1997-12-05 | 1999-06-22 | Asahi Chem Ind Co Ltd | 脊椎動物スリット蛋白質 |
| US20030096955A1 (en) * | 1998-09-01 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| JP2002538823A (ja) * | 1999-03-17 | 2002-11-19 | ワシントン・ユニバーシティ | 脊椎動物のslitDNA配列、タンパク質およびその使用 |
| WO2002006315A2 (en) * | 2000-07-18 | 2002-01-24 | Compugen Ltd. | Novel nucleic acid and amino acid sequences |
| CA2416732C (en) * | 2000-08-02 | 2016-02-09 | Brad St. Croix | Endothelial cell expression patterns |
| WO2002012346A2 (en) * | 2000-08-10 | 2002-02-14 | Pharmacia Corporation | A new slit-like protein obtained from a cdna library from hs-5 stromal cell line |
| US20040265808A1 (en) * | 2001-04-05 | 2004-12-30 | Teresa Garcia | Genes involved in osteogenesis, and methods of use |
| US20050014680A1 (en) * | 2003-04-15 | 2005-01-20 | Crabtree Gerald R. | Methods and compositions for enhancing neuron growth and survival |
| US20060025335A1 (en) * | 2004-01-30 | 2006-02-02 | Kinane Thomas B | Netrin compositions and methods of using the same |
| KR20090089462A (ko) * | 2006-12-11 | 2009-08-21 | 유니버시티 오브 유타 리써치 파운데이션 | 병적 혈관형성 및 혈관 투과성을 치료하기 위한 조성물 및 방법 |
-
2008
- 2008-09-12 EP EP08802131.6A patent/EP2212344B1/en active Active
- 2008-09-12 MX MX2010002716A patent/MX2010002716A/es not_active Application Discontinuation
- 2008-09-12 NZ NZ583851A patent/NZ583851A/en not_active IP Right Cessation
- 2008-09-12 RU RU2010114713/10A patent/RU2496790C2/ru not_active IP Right Cessation
- 2008-09-12 US US12/677,830 patent/US20110002972A1/en not_active Abandoned
- 2008-09-12 JP JP2010524408A patent/JP2010539123A/ja active Pending
- 2008-09-12 CN CN200880111279A patent/CN101821283A/zh active Pending
- 2008-09-12 WO PCT/EP2008/007579 patent/WO2009033715A2/en not_active Ceased
- 2008-09-12 CA CA2699411A patent/CA2699411A1/en not_active Abandoned
- 2008-09-12 AU AU2008297889A patent/AU2008297889A1/en not_active Abandoned
- 2008-09-12 KR KR1020107007806A patent/KR20100075493A/ko not_active Withdrawn
- 2008-09-12 BR BRPI0816784A patent/BRPI0816784A8/pt not_active IP Right Cessation
-
2010
- 2010-03-08 ZA ZA2010/01644A patent/ZA201001644B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2496790C2 (ru) | 2013-10-27 |
| CA2699411A1 (en) | 2009-03-19 |
| BRPI0816784A8 (pt) | 2016-01-19 |
| EP2212344B1 (en) | 2014-03-26 |
| JP2010539123A (ja) | 2010-12-16 |
| CN101821283A (zh) | 2010-09-01 |
| ZA201001644B (en) | 2011-03-30 |
| NZ583851A (en) | 2012-06-29 |
| BRPI0816784A2 (pt) | 2015-03-24 |
| KR20100075493A (ko) | 2010-07-02 |
| EP2212344A2 (en) | 2010-08-04 |
| RU2010114713A (ru) | 2011-10-20 |
| AU2008297889A1 (en) | 2009-03-19 |
| WO2009033715A3 (en) | 2010-03-18 |
| WO2009033715A2 (en) | 2009-03-19 |
| US20110002972A1 (en) | 2011-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights |
Owner name: FORMYCON GMBH |
|
| FA | Abandonment or withdrawal |