KR20100075493A - 퇴행성 질환의 치료를 위한 신경내분비 인자 - Google Patents
퇴행성 질환의 치료를 위한 신경내분비 인자 Download PDFInfo
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- KR20100075493A KR20100075493A KR1020107007806A KR20107007806A KR20100075493A KR 20100075493 A KR20100075493 A KR 20100075493A KR 1020107007806 A KR1020107007806 A KR 1020107007806A KR 20107007806 A KR20107007806 A KR 20107007806A KR 20100075493 A KR20100075493 A KR 20100075493A
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- A61K38/18—Growth factors; Growth regulators
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- A61K9/0012—Galenical forms characterised by the site of application
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- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07018131.8 | 2007-09-14 | ||
| EP07018131A EP2036921A1 (en) | 2007-09-14 | 2007-09-14 | Use of Slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases |
| EP08006810 | 2008-04-03 | ||
| EP08006810.9 | 2008-04-03 |
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| KR20100075493A true KR20100075493A (ko) | 2010-07-02 |
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| US (1) | US20110002972A1 (https=) |
| EP (1) | EP2212344B1 (https=) |
| JP (1) | JP2010539123A (https=) |
| KR (1) | KR20100075493A (https=) |
| CN (1) | CN101821283A (https=) |
| AU (1) | AU2008297889A1 (https=) |
| BR (1) | BRPI0816784A8 (https=) |
| CA (1) | CA2699411A1 (https=) |
| MX (1) | MX2010002716A (https=) |
| NZ (1) | NZ583851A (https=) |
| RU (1) | RU2496790C2 (https=) |
| WO (1) | WO2009033715A2 (https=) |
| ZA (1) | ZA201001644B (https=) |
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| IT1400024B1 (it) * | 2010-05-21 | 2013-05-17 | Uni Politecnica Delle Marche | Uso farmaceutico di semaforine. |
| JP2014507395A (ja) * | 2010-12-23 | 2014-03-27 | サノフイ | 肝癌の治療における使用のためのＲｏｂｏ１−Ｆｃ融合タンパク質 |
| CA2839341C (en) * | 2011-07-04 | 2020-12-15 | Mesoblast, Inc. | Methods of treating or preventing rheumatic disease |
| US9802994B2 (en) * | 2012-06-15 | 2017-10-31 | The Asan Foundation | Composition for preventing or treating fracture or osteoporosis using slit-robo system |
| ES2442242B1 (es) * | 2012-08-09 | 2014-11-25 | Biotechnology Institute, I Mas D, S.L. | Composición con factores de crecimiento destinada al tratamiento intranasal de una enfermedad neurodegenerativa u otra patología del sistema nervioso central, y su método de fabricación. |
| CN104119445A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| CN104119446A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| CN104119448A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| CN104119447A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| JPWO2015072527A1 (ja) * | 2013-11-13 | 2017-03-16 | 国立大学法人大阪大学 | ネトリン１含有破骨細胞形成抑制剤 |
| HUE068789T2 (hu) | 2014-03-14 | 2025-01-28 | Univ New York State Res Found | A csontnövekedés és a csontlebontás neurogén szabályozása |
| US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
| WO2019161136A1 (en) * | 2018-02-14 | 2019-08-22 | Cornell University | Slit and bone growth modulation |
| EP3932430A4 (en) * | 2019-02-27 | 2023-02-01 | Daewoong Pharmaceutical Co., Ltd. | ALBUMIN-RELATED COMPOSITION COMPRISING LRRD2 OF THE SLIT3 PROTEIN FOR THE PREVENTION OR TREATMENT OF BONE DISEASES |
| AU2020346062A1 (en) * | 2019-09-13 | 2022-03-24 | Rutgers, The State University Of New Jersey | AAV-compatible laminin-linker polymerization proteins |
| CN110684805B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 神经导向因子Sema基因重组慢病毒载体在制备治疗骨关节炎药物中的应用 |
| CN110721308B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种用于治疗骨关节炎的药物复方制剂及其制备方法 |
| CN110841057B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎巴布膏剂中的应用 |
| CN110694051B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎注射剂中的应用 |
| CN110711244B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎搽剂中的应用 |
| CN110772632B (zh) * | 2019-11-19 | 2023-08-11 | 四川大学华西医院 | 神经导向因子semaphorin 3a在制备治疗骨关节炎药物中的用途 |
| JP7851625B2 (ja) * | 2021-07-26 | 2026-04-27 | ピューロテックバイオ株式会社 | 宿主因子ｌｉｐｇをターゲットとした抗ｂ型肝炎ウイルス剤 |
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| FR2700117B1 (fr) * | 1993-01-07 | 1995-02-03 | Rhone Poulenc Rorer Sa | Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens. |
| JPH1116490A (ja) * | 1997-06-26 | 1999-01-22 | Kyocera Corp | プラズマディスプレイパネル用隔壁の製造方法及びプラズマディスプレイパネル用基板 |
| US20030032057A1 (en) * | 1997-08-26 | 2003-02-13 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| AU1203999A (en) * | 1997-10-31 | 1999-05-24 | Osiris Therapeutics, Inc. | Human slit polypeptide and polynucleotides encoding same |
| JPH11164690A (ja) * | 1997-12-05 | 1999-06-22 | Asahi Chem Ind Co Ltd | 脊椎動物スリット蛋白質 |
| US20030096955A1 (en) * | 1998-09-01 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| CA2365214A1 (en) * | 1999-03-17 | 2000-09-21 | Washington University | Vertebrate protein slit, dna sequence encoding it and uses thereof |
| WO2002006315A2 (en) * | 2000-07-18 | 2002-01-24 | Compugen Ltd. | Novel nucleic acid and amino acid sequences |
| JP2004527210A (ja) * | 2000-08-02 | 2004-09-09 | ザ ジョンズ ホプキンス ユニバーシティー | 内皮細胞発現パターンの評価法 |
| AU2001286446A1 (en) * | 2000-08-10 | 2002-02-18 | Pharmacia Corporation | A new slit-like protein obtained from a cdna library from hs-5 stromal cell line |
| US20040265808A1 (en) * | 2001-04-05 | 2004-12-30 | Teresa Garcia | Genes involved in osteogenesis, and methods of use |
| US20050014680A1 (en) * | 2003-04-15 | 2005-01-20 | Crabtree Gerald R. | Methods and compositions for enhancing neuron growth and survival |
| US20060025335A1 (en) * | 2004-01-30 | 2006-02-02 | Kinane Thomas B | Netrin compositions and methods of using the same |
| BRPI0720038A2 (pt) * | 2006-12-11 | 2013-12-24 | Univ Utah Res Found | Métodos para inibir a permeabilidade vascular em tecido, para triar ou avaliar um agente que inibe a permeabilidade vascular, para tratar ou prevenir a síndrome da angústia respiratória, a retinopatia de prematuridade, a retinopatia diabética e a degeneração macular úmida em um indivíduo, para tratar indivíduos com sugestões repulsivas ou miméticos e para promover a angiogênese em um tecido, polipeptídeo isolado, ácido nucleico isolado, e, vetor |
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| US20110002972A1 (en) | 2011-01-06 |
| RU2496790C2 (ru) | 2013-10-27 |
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| JP2010539123A (ja) | 2010-12-16 |
| RU2010114713A (ru) | 2011-10-20 |
| BRPI0816784A8 (pt) | 2016-01-19 |
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| BRPI0816784A2 (pt) | 2015-03-24 |
| AU2008297889A1 (en) | 2009-03-19 |
| NZ583851A (en) | 2012-06-29 |
| CN101821283A (zh) | 2010-09-01 |
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