MX2010001319A - Metodo para producir proteinas heterogeneas. - Google Patents

Metodo para producir proteinas heterogeneas.

Info

Publication number
MX2010001319A
MX2010001319A MX2010001319A MX2010001319A MX2010001319A MX 2010001319 A MX2010001319 A MX 2010001319A MX 2010001319 A MX2010001319 A MX 2010001319A MX 2010001319 A MX2010001319 A MX 2010001319A MX 2010001319 A MX2010001319 A MX 2010001319A
Authority
MX
Mexico
Prior art keywords
heterogeneous protein
producing
producing heterogeneous
protein
polypeptide
Prior art date
Application number
MX2010001319A
Other languages
English (en)
Inventor
Hisahiro Tabuchi
Tomoya Sugiyama
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of MX2010001319A publication Critical patent/MX2010001319A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01002—Alanine transaminase (2.6.1.2), i.e. alanine-aminotransferase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención proporciona un método capaz de producir una proteína natural o recombinante en rendimiento elevado. La presente invención se relaciona con un método para producir un polipéptido, que comprende cultivar una célula que expresa fuertemente aminotransferasa de alanina y tiene un ADN transferido que codifica un polipéptido deseado de esta manera permitir que la célula produzca el polipéptido.
MX2010001319A 2007-08-07 2008-08-06 Metodo para producir proteinas heterogeneas. MX2010001319A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007205158 2007-08-07
PCT/JP2008/064095 WO2009020144A1 (ja) 2007-08-07 2008-08-06 異種タンパク質の製造方法

Publications (1)

Publication Number Publication Date
MX2010001319A true MX2010001319A (es) 2010-06-01

Family

ID=40341376

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010001319A MX2010001319A (es) 2007-08-07 2008-08-06 Metodo para producir proteinas heterogeneas.

Country Status (15)

Country Link
US (3) US8697397B2 (es)
EP (1) EP2186905B1 (es)
JP (1) JP5337033B2 (es)
KR (1) KR101577839B1 (es)
CN (1) CN101809161B (es)
AU (1) AU2008284753B2 (es)
BR (1) BRPI0815036B1 (es)
CA (1) CA2695849C (es)
DK (1) DK2186905T3 (es)
ES (1) ES2591284T3 (es)
HK (1) HK1143608A1 (es)
MX (1) MX2010001319A (es)
RU (1) RU2487168C2 (es)
TW (1) TWI463013B (es)
WO (1) WO2009020144A1 (es)

Families Citing this family (17)

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CA2649148C (en) 2006-04-13 2016-08-23 Chugai Seiyaku Kabushiki Kaisha Taurine transporter gene
US20100233759A1 (en) 2007-03-15 2010-09-16 Chugai Seiyaku Kabushiki Kaisha Method for production of polypeptide
WO2009020144A1 (ja) 2007-08-07 2009-02-12 Chugai Seiyaku Kabushiki Kaisha 異種タンパク質の製造方法
JP5337043B2 (ja) 2007-10-15 2013-11-06 中外製薬株式会社 異種タンパク質を高生産する細胞の作製方法
CA2703493C (en) 2007-10-24 2016-11-08 Chugai Seiyaku Kabushiki Kaisha A cell for use in production of heteroproteins and production method using the same
EP2423309B1 (en) * 2009-04-22 2018-01-03 Chugai Seiyaku Kabushiki Kaisha A method for producing a cell capable of high-yield production of heteroproteins
HUE030820T2 (en) 2010-05-28 2017-06-28 Hoffmann La Roche Decreasing Lactate Levels and Enhancing Polypeptide Production by Control of Lactate Dehydrogenase and Pyruvate Dehydrogenase Kinase Expression
MX352229B (es) 2011-04-01 2017-11-15 Chugai Pharmaceutical Co Ltd Metodo de produccion de polipeptido recombinante.
US11608508B2 (en) * 2012-10-10 2023-03-21 Chugai Seiyaku Kabushiki Kaisha Method for establishing modified host cell
SI2970875T1 (sl) 2013-03-15 2020-08-31 F. Hoffmann-La Roche Ag Sestavki celičnih kultur z antioksidanti in postpoki za proizvodnjo polipeptidov
JP6708548B2 (ja) * 2013-12-20 2020-06-10 ノバルティス アーゲー 新規真核細胞および目的の生成物を組換え発現させるための方法
EP3083677B1 (en) 2013-12-20 2019-08-28 Novartis AG Novel eukaryotic cells and methods for recombinantly expressing a product of interest
CN103923872B (zh) * 2014-04-17 2015-11-18 湖北工业大学 一种米曲霉活力强化剂及其培养方法
CN106233219B (zh) * 2015-03-31 2020-03-17 深圳市大疆创新科技有限公司 移动平台操作系统及方法
TWI797060B (zh) * 2015-08-04 2023-04-01 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
CN113242907A (zh) 2018-12-11 2021-08-10 富士胶片株式会社 动物细胞、动物细胞的制造方法及靶蛋白的制造方法
KR102479900B1 (ko) * 2020-12-11 2022-12-26 대한민국 내염성 증진 신품종 식물

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JPH07507446A (ja) * 1992-03-04 1995-08-24 シナプティック・ファーマスーティカル・コーポレーション タウリン及びｇａｂａの輸送体をコードするｄｎａ並びにその使用
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CA2649148C (en) 2006-04-13 2016-08-23 Chugai Seiyaku Kabushiki Kaisha Taurine transporter gene
US20100233759A1 (en) * 2007-03-15 2010-09-16 Chugai Seiyaku Kabushiki Kaisha Method for production of polypeptide
WO2009020144A1 (ja) * 2007-08-07 2009-02-12 Chugai Seiyaku Kabushiki Kaisha 異種タンパク質の製造方法
JP5337043B2 (ja) * 2007-10-15 2013-11-06 中外製薬株式会社 異種タンパク質を高生産する細胞の作製方法
CA2703493C (en) * 2007-10-24 2016-11-08 Chugai Seiyaku Kabushiki Kaisha A cell for use in production of heteroproteins and production method using the same
EP2423309B1 (en) * 2009-04-22 2018-01-03 Chugai Seiyaku Kabushiki Kaisha A method for producing a cell capable of high-yield production of heteroproteins

Also Published As

Publication number Publication date
TWI463013B (zh) 2014-12-01
RU2010108308A (ru) 2011-09-20
US8697397B2 (en) 2014-04-15
ES2591284T3 (es) 2016-11-25
CN101809161A (zh) 2010-08-18
CA2695849C (en) 2018-10-16
BRPI0815036B1 (pt) 2022-09-20
JP5337033B2 (ja) 2013-11-06
DK2186905T3 (en) 2016-09-19
KR101577839B1 (ko) 2015-12-15
US20100167346A1 (en) 2010-07-01
CA2695849A1 (en) 2009-02-12
CN101809161B (zh) 2014-03-12
HK1143608A1 (en) 2011-01-07
US9499618B2 (en) 2016-11-22
EP2186905B1 (en) 2016-07-13
BRPI0815036A2 (pt) 2014-10-14
TW200920845A (en) 2009-05-16
KR20100057598A (ko) 2010-05-31
AU2008284753A1 (en) 2009-02-12
AU2008284753B2 (en) 2014-01-16
WO2009020144A1 (ja) 2009-02-12
EP2186905A1 (en) 2010-05-19
US20140309405A1 (en) 2014-10-16
US20150315624A1 (en) 2015-11-05
US9284374B2 (en) 2016-03-15
EP2186905A4 (en) 2010-09-01
JPWO2009020144A1 (ja) 2010-11-04
RU2487168C2 (ru) 2013-07-10

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