MX2009013197A - Derivados terapeuticos de pirazolonaftiridina. - Google Patents
Derivados terapeuticos de pirazolonaftiridina.Info
- Publication number
- MX2009013197A MX2009013197A MX2009013197A MX2009013197A MX2009013197A MX 2009013197 A MX2009013197 A MX 2009013197A MX 2009013197 A MX2009013197 A MX 2009013197A MX 2009013197 A MX2009013197 A MX 2009013197A MX 2009013197 A MX2009013197 A MX 2009013197A
- Authority
- MX
- Mexico
- Prior art keywords
- gabaa
- formula
- therapeutic
- animal
- compound
- Prior art date
Links
- VMPCBEQFWHYVIV-UHFFFAOYSA-N C1=CC=N[C]2N[C]3C=NN=C3C=C21 Chemical class C1=CC=N[C]2N[C]3C=NN=C3C=C21 VMPCBEQFWHYVIV-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 102000027484 GABAA receptors Human genes 0.000 abstract 2
- 108091008681 GABAA receptors Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical compound N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94300007P | 2007-06-08 | 2007-06-08 | |
| PCT/US2008/066211 WO2008154447A1 (en) | 2007-06-08 | 2008-06-06 | Therapeutic pyrazolonaphthyridine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009013197A true MX2009013197A (es) | 2010-04-27 |
Family
ID=40130166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009013197A MX2009013197A (es) | 2007-06-08 | 2008-06-06 | Derivados terapeuticos de pirazolonaftiridina. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7858614B2 (enExample) |
| EP (1) | EP2166853B1 (enExample) |
| JP (1) | JP2010529145A (enExample) |
| KR (1) | KR20100036306A (enExample) |
| CN (1) | CN101754681A (enExample) |
| AU (1) | AU2008261803A1 (enExample) |
| BR (1) | BRPI0812369A2 (enExample) |
| CA (1) | CA2689934A1 (enExample) |
| ES (1) | ES2483728T3 (enExample) |
| IL (1) | IL202287A0 (enExample) |
| MX (1) | MX2009013197A (enExample) |
| WO (1) | WO2008154447A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7863266B2 (en) * | 2007-06-08 | 2011-01-04 | Helicon Therapeutics, Inc. | Therapeutic pyrazoloquinoline urea derivatives |
| US9012470B2 (en) | 2010-10-14 | 2015-04-21 | Dart Neuroscience (Cayman) Ltd. | Therapeutic 5,6,5-tricyclic analogs |
| US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
| US10531200B2 (en) * | 2015-10-23 | 2020-01-07 | Harman International Industries, Incorporated | Dual asymmetric compression driver |
| CN106810550A (zh) * | 2017-01-10 | 2017-06-09 | 湖南华腾制药有限公司 | 一种萘啶衍生物的制备方法 |
| US11485733B2 (en) | 2017-06-30 | 2022-11-01 | Bayer Animal Health Gmbh | Azaquinoline derivatives |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3204126A1 (de) * | 1982-02-06 | 1983-08-11 | Bayer Ag, 5090 Leverkusen | Pyrazoloxazine, -thiazine, -chinoline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4479955A (en) * | 1983-01-10 | 1984-10-30 | Ciba-Geigy Corporation | Heterocycle-fused pyrazolo[3,4-d]pyridin-3-ones as benzodiazepine receptor modulators |
| US4814450A (en) | 1984-07-09 | 1989-03-21 | Ciba-Geigy Corporation | Certain ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives |
| JPS61112075A (ja) * | 1984-11-05 | 1986-05-30 | Shionogi & Co Ltd | チエニルピラゾロキノリン誘導体 |
| EP0214092A1 (en) | 1985-08-08 | 1987-03-11 | Ciba-Geigy Ag | Enhanced absorption of psychoactive 2-aryl-pyrazolo quinolines as a solid molecular dispersion in polyvinylpyrrolidone |
| US4817450A (en) * | 1987-11-30 | 1989-04-04 | Spedco, Inc. | Pressure/temperature test plug assembly |
| FR2695126B1 (fr) * | 1992-08-27 | 1994-11-10 | Sanofi Elf | Dérivés d'acide thiényl ou pyrrolyl carboxyliques, leur préparation et médicaments les contenant. |
| US5334595A (en) * | 1992-10-23 | 1994-08-02 | Sterling Winthrop Inc. | Pyrazoloquinolones as anticancer agents |
| RU2145606C1 (ru) * | 1994-05-24 | 2000-02-20 | Ф.Хоффманн-Ля Рош Аг | Трициклические дикарбонильные производные и лекарственный препарат на их основе |
| GB9716344D0 (en) * | 1997-08-01 | 1997-10-08 | Merck Sharp & Dohme | Therapeutic compounds |
| GB9716347D0 (en) * | 1997-08-01 | 1997-10-08 | Merck Sharp & Dohme | Therapeutic compounds |
| GB9716345D0 (en) * | 1997-08-01 | 1997-10-08 | Merck Sharp & Dohme | Therapeutic compounds |
| TWI271406B (en) * | 1999-12-13 | 2007-01-21 | Eisai Co Ltd | Tricyclic condensed heterocyclic compounds, preparation method of the same and pharmaceuticals comprising the same |
| GB0108475D0 (en) * | 2001-04-04 | 2001-05-23 | Merck Sharp & Dohme | New compounds |
| JP3896309B2 (ja) * | 2001-07-09 | 2007-03-22 | ファイザー株式会社 | プロテインキナーゼｃ阻害物質としてのピラゾロキノリノン誘導体 |
| ATE425164T1 (de) * | 2002-12-16 | 2009-03-15 | Active Biotech Ab | Tetrazyklische immunmodulierende verbindungen |
| AR045689A1 (es) * | 2003-05-29 | 2005-11-09 | Millennium Pharm Inc | Compuestos derivados de 2,5-dihidro-pirazolo[4,3-c]quinolin-4-ona como inhibidores de chk-1 y composiciones farmaceuticas que los contienen |
| US7544697B2 (en) * | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
| CN1893943A (zh) * | 2003-10-03 | 2007-01-10 | 3M创新有限公司 | 吡唑并吡啶和其类似物 |
| AU2006287378A1 (en) * | 2005-09-07 | 2007-03-15 | Braincells, Inc. | Modulation of neurogenesis by HDac inhibition |
| ES2386168T3 (es) * | 2007-06-08 | 2012-08-10 | Helicon Therapeutics, Inc. | Derivados de pirazoloquinolina terapéuticos |
-
2008
- 2008-06-06 ES ES08770412.8T patent/ES2483728T3/es active Active
- 2008-06-06 US US12/135,045 patent/US7858614B2/en not_active Expired - Fee Related
- 2008-06-06 JP JP2010511393A patent/JP2010529145A/ja active Pending
- 2008-06-06 CA CA2689934A patent/CA2689934A1/en not_active Abandoned
- 2008-06-06 MX MX2009013197A patent/MX2009013197A/es active IP Right Grant
- 2008-06-06 BR BRPI0812369A patent/BRPI0812369A2/pt not_active IP Right Cessation
- 2008-06-06 KR KR1020107000331A patent/KR20100036306A/ko not_active Withdrawn
- 2008-06-06 AU AU2008261803A patent/AU2008261803A1/en not_active Abandoned
- 2008-06-06 CN CN200880025152A patent/CN101754681A/zh active Pending
- 2008-06-06 EP EP08770412.8A patent/EP2166853B1/en not_active Not-in-force
- 2008-06-06 WO PCT/US2008/066211 patent/WO2008154447A1/en not_active Ceased
-
2009
- 2009-11-23 IL IL202287A patent/IL202287A0/en unknown
-
2010
- 2010-11-18 US US12/949,619 patent/US8497262B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HK1142774A1 (en) | 2010-12-17 |
| EP2166853B1 (en) | 2014-05-28 |
| EP2166853A4 (en) | 2011-04-06 |
| CN101754681A (zh) | 2010-06-23 |
| KR20100036306A (ko) | 2010-04-07 |
| US20110065692A1 (en) | 2011-03-17 |
| AU2008261803A1 (en) | 2008-12-18 |
| WO2008154447A1 (en) | 2008-12-18 |
| EP2166853A1 (en) | 2010-03-31 |
| BRPI0812369A2 (pt) | 2016-08-09 |
| JP2010529145A (ja) | 2010-08-26 |
| US8497262B2 (en) | 2013-07-30 |
| ES2483728T3 (es) | 2014-08-07 |
| IL202287A0 (en) | 2010-06-16 |
| US20090005365A1 (en) | 2009-01-01 |
| US7858614B2 (en) | 2010-12-28 |
| CA2689934A1 (en) | 2008-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |