MX2009012706A - Proceso para preparar triazolonas. - Google Patents

Proceso para preparar triazolonas.

Info

Publication number
MX2009012706A
MX2009012706A MX2009012706A MX2009012706A MX2009012706A MX 2009012706 A MX2009012706 A MX 2009012706A MX 2009012706 A MX2009012706 A MX 2009012706A MX 2009012706 A MX2009012706 A MX 2009012706A MX 2009012706 A MX2009012706 A MX 2009012706A
Authority
MX
Mexico
Prior art keywords
triazolones
preparing
preparation
improved method
useful intermediates
Prior art date
Application number
MX2009012706A
Other languages
English (en)
Inventor
Michael Martin
Keshab Sarma
Jiang Zhu
Humberto Bartolome Arzeno
Gary M Lee
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2009012706A publication Critical patent/MX2009012706A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/18—Preparation of halogenated hydrocarbons by replacement by halogens of oxygen atoms of carbonyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/14—Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La presente proceso proporciona un método mejorado para la preparación de triazoles sustituidos con alquilsulfanilo (2) que son intermediarios útiles en un nuevo proceso para la preparación de triazolonas (20).
MX2009012706A 2007-05-30 2008-05-20 Proceso para preparar triazolonas. MX2009012706A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93221607P 2007-05-30 2007-05-30
PCT/EP2008/056166 WO2008145563A2 (en) 2007-05-30 2008-05-20 Process for preparing triazolones

Publications (1)

Publication Number Publication Date
MX2009012706A true MX2009012706A (es) 2009-12-08

Family

ID=39645556

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012706A MX2009012706A (es) 2007-05-30 2008-05-20 Proceso para preparar triazolonas.

Country Status (13)

Country Link
US (2) US7745634B2 (es)
EP (1) EP2164835B1 (es)
JP (1) JP5341881B2 (es)
KR (1) KR101541929B1 (es)
CN (1) CN101679320B (es)
AU (1) AU2008257772B2 (es)
BR (2) BR122021006634B1 (es)
CA (2) CA2912224C (es)
EA (1) EA016913B1 (es)
ES (1) ES2401037T3 (es)
IL (1) IL202142A (es)
MX (1) MX2009012706A (es)
WO (1) WO2008145563A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2593419A1 (en) * 2010-07-15 2013-05-22 Albemarle Corporation Processes for producing 4-bromo-2-methoxybenzaldehyde
US9039765B2 (en) 2011-01-21 2015-05-26 Warsaw Orhtopedic, Inc. Implant system and method for stabilization of a sacro-iliac joint
CN102584689A (zh) * 2012-01-13 2012-07-18 江苏中邦制药有限公司 一种2-氯-3-氟吡啶的制备方法
CN109384765A (zh) * 2012-09-26 2019-02-26 默沙东公司 逆转录酶抑制剂的晶型
US20210261512A1 (en) * 2018-05-04 2021-08-26 Inflazome Limited Novel compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200505441A (en) * 2003-03-24 2005-02-16 Hoffmann La Roche Non-nucleoside reverse transcriptase inhibitorsⅠ
WO2005100323A1 (en) * 2004-04-15 2005-10-27 F. Hoffmann-La Roche Ag Process for preparing pyridazinone compounds
WO2005112811A1 (en) * 2004-05-14 2005-12-01 Cardima, Inc. Ablation probe with stabilizing member
JP4675959B2 (ja) * 2004-07-27 2011-04-27 エフ．ホフマン−ラ ロシュ アーゲー 非ヌクレオシド逆転写酵素阻害剤としてのベンジルトリアゾロン化合物
CN101657433A (zh) * 2007-03-29 2010-02-24 弗·哈夫曼-拉罗切有限公司 非核苷逆转录酶抑制剂

Also Published As

Publication number Publication date
AU2008257772A1 (en) 2008-12-04
EP2164835A2 (en) 2010-03-24
ES2401037T3 (es) 2013-04-16
US7745634B2 (en) 2010-06-29
CA2687770C (en) 2016-03-08
BRPI0811988A2 (pt) 2020-08-18
JP5341881B2 (ja) 2013-11-13
CA2687770A1 (en) 2008-12-04
EA200901598A1 (ru) 2010-06-30
IL202142A0 (en) 2010-06-16
CA2912224A1 (en) 2008-12-04
US20090012304A1 (en) 2009-01-08
KR101541929B1 (ko) 2015-08-04
US7893276B2 (en) 2011-02-22
CN101679320A (zh) 2010-03-24
WO2008145563A3 (en) 2009-04-09
WO2008145563A2 (en) 2008-12-04
AU2008257772B2 (en) 2013-06-20
CN101679320B (zh) 2013-01-23
EA016913B1 (ru) 2012-08-30
BRPI0811988B1 (pt) 2021-05-25
BR122021006634B1 (pt) 2022-03-29
CA2912224C (en) 2018-04-24
EP2164835B1 (en) 2012-12-12
US20100280256A1 (en) 2010-11-04
JP2010528084A (ja) 2010-08-19
KR20100023010A (ko) 2010-03-03
IL202142A (en) 2015-06-30

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Legal Events

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