MX2009010450A - El uso de inhibidores de la fosfodiesterasa 7 para el tratamiento transtornos del movimiento. - Google Patents
El uso de inhibidores de la fosfodiesterasa 7 para el tratamiento transtornos del movimiento.Info
- Publication number
- MX2009010450A MX2009010450A MX2009010450A MX2009010450A MX2009010450A MX 2009010450 A MX2009010450 A MX 2009010450A MX 2009010450 A MX2009010450 A MX 2009010450A MX 2009010450 A MX2009010450 A MX 2009010450A MX 2009010450 A MX2009010450 A MX 2009010450A
- Authority
- MX
- Mexico
- Prior art keywords
- disease
- pde7
- parkinson
- inhibitory agent
- treatment
- Prior art date
Links
- 208000016285 Movement disease Diseases 0.000 title abstract 2
- 229940123304 Phosphodiesterase 7 inhibitor Drugs 0.000 title 1
- 239000002606 phosphodiesterase VII inhibitor Substances 0.000 title 1
- 101100407335 Dictyostelium discoideum pde7 gene Proteins 0.000 abstract 3
- 208000018737 Parkinson disease Diseases 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 3
- 230000007170 pathology Effects 0.000 abstract 2
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 abstract 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 abstract 1
- 206010038743 Restlessness Diseases 0.000 abstract 1
- 230000005856 abnormality Effects 0.000 abstract 1
- 239000003136 dopamine receptor stimulating agent Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960004502 levodopa Drugs 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/527—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim spiro-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92049607P | 2007-03-27 | 2007-03-27 | |
| PCT/US2008/058530 WO2008119057A2 (en) | 2007-03-27 | 2008-03-27 | The use of pde7 inhibitors for the treatment of movement disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009010450A true MX2009010450A (es) | 2009-11-23 |
Family
ID=39789284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009010450A MX2009010450A (es) | 2007-03-27 | 2008-03-27 | El uso de inhibidores de la fosfodiesterasa 7 para el tratamiento transtornos del movimiento. |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20080260643A1 (enExample) |
| EP (1) | EP2139475B1 (enExample) |
| JP (2) | JP5580192B2 (enExample) |
| CN (2) | CN101917992A (enExample) |
| AU (1) | AU2008230710B2 (enExample) |
| CA (1) | CA2681650C (enExample) |
| ES (1) | ES2533206T3 (enExample) |
| MX (1) | MX2009010450A (enExample) |
| NZ (1) | NZ580413A (enExample) |
| RU (1) | RU2449790C2 (enExample) |
| WO (1) | WO2008119057A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8637528B2 (en) * | 2007-03-27 | 2014-01-28 | Omeros Corporation | Use of PDE7 inhibitors for the treatment of movement disorders |
| WO2010111060A1 (en) * | 2009-03-23 | 2010-09-30 | Merck Sharp & Dohme Corp. | P2x3, receptor antagonists for treatment of pain |
| FR2943673B1 (fr) * | 2009-03-27 | 2013-03-29 | Sanofi Aventis | Applications therapeutiques de derives de quinazolinedione |
| FR2944282B1 (fr) | 2009-04-09 | 2013-05-03 | Sanofi Aventis | Derives de quinazolinedione, leur preparation et leurs diverses applications therapeutiques |
| FR2944206B1 (fr) | 2009-04-09 | 2012-12-28 | Sanofi Aventis | Applications therapeutiques dans le domaine cardiovasculaire de derives de quinazolinedione |
| AU2013202493B2 (en) * | 2009-05-04 | 2016-03-10 | Omeros Corporation | Use of PDE7 inhibitors for the treatment of movement disorders |
| ES2353093B1 (es) | 2009-05-20 | 2012-01-03 | Consejo Superior De Investigaciones Científicas (Csic) | Uso de derivados de quinazolinas y sus composiciones farmacéuticas en enfermedades neurodegenerativas. |
| ES2360783B1 (es) | 2009-10-02 | 2012-07-04 | Consejo Superior De Investigaciones Científicas (Csic) | 1,2,4-tiadiazoles-5-imino sustituidos utiles en el tratamiento de enfermedades neurodegenerativas |
| US9220715B2 (en) | 2010-11-08 | 2015-12-29 | Omeros Corporation | Treatment of addiction and impulse-control disorders using PDE7 inhibitors |
| CN103547267A (zh) * | 2010-11-08 | 2014-01-29 | 奥默罗斯公司 | 使用pde7抑制剂治疗成瘾和冲动控制障碍 |
| PL2846805T3 (pl) * | 2012-05-07 | 2019-05-31 | Omeros Corp | Leczenie uzależnień i zaburzeń kontroli impulsów za pomocą inhibitorów PDE7 |
| HUE043518T2 (hu) * | 2012-05-07 | 2019-08-28 | Omeros Corp | Függõség és impulzuskontroll zavarok kezelése PDE-7-inhibitorok alkalmazásával |
| KR20190040054A (ko) * | 2016-08-26 | 2019-04-16 | 미쓰비시 타나베 파마 코퍼레이션 | 이환식 함질소 헤테로환 화합물 |
| US20210330736A1 (en) * | 2018-09-05 | 2021-10-28 | Universiteit Van Amsterdam | Use of a pde11 or pde2 inhibitor for the treatment of parkinson's disease |
| EP4572765A1 (en) | 2022-08-18 | 2025-06-25 | Mitodicure GmbH | Use of a therapeutic agent with phosphodiesterase-7 inhibitory activity for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or exertional intolerance |
| WO2024259383A2 (en) * | 2023-06-14 | 2024-12-19 | President And Fellows Of Harvard College | Ion channel binders and uses thereof |
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| US8637528B2 (en) * | 2007-03-27 | 2014-01-28 | Omeros Corporation | Use of PDE7 inhibitors for the treatment of movement disorders |
-
2008
- 2008-03-27 US US12/057,368 patent/US20080260643A1/en not_active Abandoned
- 2008-03-27 MX MX2009010450A patent/MX2009010450A/es active IP Right Grant
- 2008-03-27 AU AU2008230710A patent/AU2008230710B2/en active Active
- 2008-03-27 ES ES08744515.1T patent/ES2533206T3/es active Active
- 2008-03-27 EP EP08744515.1A patent/EP2139475B1/en active Active
- 2008-03-27 WO PCT/US2008/058530 patent/WO2008119057A2/en not_active Ceased
- 2008-03-27 RU RU2009138966/15A patent/RU2449790C2/ru active
- 2008-03-27 CN CN200880017058XA patent/CN101917992A/zh active Pending
- 2008-03-27 NZ NZ580413A patent/NZ580413A/xx unknown
- 2008-03-27 CA CA2681650A patent/CA2681650C/en active Active
- 2008-03-27 CN CN201510082785.6A patent/CN104758291B/zh active Active
- 2008-03-27 JP JP2010501232A patent/JP5580192B2/ja active Active
-
2010
- 2010-12-21 US US12/974,693 patent/US20110091388A1/en not_active Abandoned
-
2014
- 2014-05-28 JP JP2014109910A patent/JP5943964B2/ja active Active
-
2018
- 2018-12-06 US US16/212,064 patent/US20190183824A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014198718A (ja) | 2014-10-23 |
| RU2449790C2 (ru) | 2012-05-10 |
| BRPI0809244A2 (pt) | 2014-09-23 |
| EP2139475A2 (en) | 2010-01-06 |
| EP2139475A4 (en) | 2012-03-07 |
| JP5580192B2 (ja) | 2014-08-27 |
| WO2008119057A3 (en) | 2008-11-20 |
| EP2139475B1 (en) | 2014-12-17 |
| AU2008230710A1 (en) | 2008-10-02 |
| WO2008119057A2 (en) | 2008-10-02 |
| CN104758291B (zh) | 2020-03-03 |
| AU2008230710B2 (en) | 2014-04-10 |
| CA2681650A1 (en) | 2008-10-02 |
| CN101917992A (zh) | 2010-12-15 |
| US20080260643A1 (en) | 2008-10-23 |
| ES2533206T3 (es) | 2015-04-08 |
| RU2009138966A (ru) | 2011-05-10 |
| CA2681650C (en) | 2016-11-22 |
| JP5943964B2 (ja) | 2016-07-05 |
| NZ580413A (en) | 2012-11-30 |
| HK1139861A1 (en) | 2010-09-30 |
| CN104758291A (zh) | 2015-07-08 |
| US20110091388A1 (en) | 2011-04-21 |
| US20190183824A1 (en) | 2019-06-20 |
| JP2010522768A (ja) | 2010-07-08 |
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