MX2009008985A - Procedimiento para la preparacion de sal acetato de metil ester de (2r,3s)-3-fenilisoserina. - Google Patents

Procedimiento para la preparacion de sal acetato de metil ester de (2r,3s)-3-fenilisoserina.

Info

Publication number
MX2009008985A
MX2009008985A MX2009008985A MX2009008985A MX2009008985A MX 2009008985 A MX2009008985 A MX 2009008985A MX 2009008985 A MX2009008985 A MX 2009008985A MX 2009008985 A MX2009008985 A MX 2009008985A MX 2009008985 A MX2009008985 A MX 2009008985A
Authority
MX
Mexico
Prior art keywords
methyl ester
acetate salt
preparation
ester acetate
phenylisoserine
Prior art date
Application number
MX2009008985A
Other languages
English (en)
Inventor
Bruno Gabetta
Daniele Ciceri
Nicola Vignola
Frieder Mitzel
Beat T Weber
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of MX2009008985A publication Critical patent/MX2009008985A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/08—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)

Abstract

Un procedimiento para la preparación enantioselectiva de la sal acetato de metil éster de (2R,3S)-3-fenilisoserina de fórmula (I) (ver fórmula (I)) que es un bloque constructor útil para la síntesis y derivados de taxano; el procedimiento involucra la resolución de la amida de treo-fenilisoserina racémica y su conversión a (I).
MX2009008985A 2007-02-22 2008-02-11 Procedimiento para la preparacion de sal acetato de metil ester de (2r,3s)-3-fenilisoserina. MX2009008985A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07003642A EP1961735B1 (en) 2007-02-22 2007-02-22 Process for the preparation of (2r,3s)-3-phenylisoserine methyl ester acetate salt
PCT/EP2008/001015 WO2008101608A1 (en) 2007-02-22 2008-02-11 Process for the preparation of (2r,3s)-3-phenylisoserine methyl ester acetate salt

Publications (1)

Publication Number Publication Date
MX2009008985A true MX2009008985A (es) 2009-09-02

Family

ID=38230004

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009008985A MX2009008985A (es) 2007-02-22 2008-02-11 Procedimiento para la preparacion de sal acetato de metil ester de (2r,3s)-3-fenilisoserina.

Country Status (19)

Country Link
US (1) US8106231B2 (es)
EP (1) EP1961735B1 (es)
JP (1) JP5352478B2 (es)
KR (1) KR101499817B1 (es)
CN (1) CN101675028B (es)
AT (1) ATE449062T1 (es)
AU (1) AU2008217318B2 (es)
CA (1) CA2679159C (es)
DE (1) DE602007003312D1 (es)
DK (1) DK1961735T3 (es)
ES (1) ES2333266T3 (es)
HK (1) HK1121735A1 (es)
IL (1) IL200537A (es)
MX (1) MX2009008985A (es)
PL (1) PL1961735T3 (es)
PT (1) PT1961735E (es)
RU (1) RU2459802C2 (es)
SI (1) SI1961735T1 (es)
WO (1) WO2008101608A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2380871B1 (en) * 2010-04-15 2013-01-09 Indena S.p.A. A process for the preparation of isoserine derivatives
EP2399904A1 (en) * 2010-05-26 2011-12-28 Nabriva Therapeutics AG Process for the preparation of pleuromutilins

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2275378A (en) * 1937-09-10 1942-03-03 Rohm & Haas Polyalkylene ether disulphonyl halides and a process of making them
US4695589A (en) * 1976-06-25 1987-09-22 Sterling Drug Inc. Alpha-(aminoalkyl-4-hydroxy-3-(alkylthio)benzenemethanols
FR2415640A1 (fr) * 1978-01-27 1979-08-24 Nativelle Sa Ets Derives d'amino-3-cardenolides, procede pour leur preparation, et medicaments les contenant
ZA794872B (en) * 1978-09-20 1980-11-26 Schering Corp A phenylalkylaminoethylsalicylamide,its preparation and pharmaceutical compositions containing it
FR2688499B1 (fr) * 1992-03-10 1994-05-06 Rhone Poulenc Rorer Sa Procede de preparation de la beta-phenylisoserine et de ses analogues.
JPH06271512A (ja) * 1993-03-22 1994-09-27 Toray Ind Inc 光学活性トランス−１，２−ジアミノ−４−シクロヘキセンの製造方法
US6025516A (en) * 1998-10-14 2000-02-15 Chiragene, Inc. Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes
EP1383754B1 (en) * 2001-03-23 2011-02-23 ScinoPharm Taiwan, Ltd. Process for making taxane derivatives
US7034178B2 (en) * 2001-07-03 2006-04-25 Altana Pharma Ag Process for the production of 3-phenylisoserine
CN1315777C (zh) * 2003-01-16 2007-05-16 东丽泛应化学(股) 旋光二酰基酒石酸的回收方法
FR2861073B1 (fr) * 2003-10-17 2006-01-06 Sanofi Synthelabo Derives de n-[heteroaryl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique
US20080249310A1 (en) * 2004-07-23 2008-10-09 Thijs Kuilman Process For the Preparation of (2R,3R)-2-Hydroxy-3-Amino-3-Aryl-Propionamide and (2R,3R)-2-Hydroxy-3-Amino-3-Aryl-Propionic Acid Alkyl Ester
AR057061A1 (es) * 2005-06-16 2007-11-14 Altana Pharma Ag Espiro-bencimidazoles farmaceuticamente activos y su uso en la fabricacion de medicamentos
JP2009114065A (ja) * 2006-02-21 2009-05-28 Kaneka Corp （２ｒ，３ｒ）および（２ｓ，３ｓ）−３−フェニルイソセリン誘導体の製造法

Also Published As

Publication number Publication date
US20100168460A1 (en) 2010-07-01
EP1961735A1 (en) 2008-08-27
WO2008101608A1 (en) 2008-08-28
DE602007003312D1 (de) 2009-12-31
IL200537A0 (en) 2010-04-29
DK1961735T3 (da) 2010-03-29
KR101499817B1 (ko) 2015-03-06
US8106231B2 (en) 2012-01-31
SI1961735T1 (sl) 2010-01-29
JP2010519262A (ja) 2010-06-03
ATE449062T1 (de) 2009-12-15
KR20090113859A (ko) 2009-11-02
PL1961735T3 (pl) 2010-04-30
AU2008217318B2 (en) 2013-01-17
CA2679159C (en) 2015-11-03
RU2459802C2 (ru) 2012-08-27
CA2679159A1 (en) 2008-08-28
JP5352478B2 (ja) 2013-11-27
RU2009131595A (ru) 2011-02-27
AU2008217318A1 (en) 2008-08-28
ES2333266T3 (es) 2010-02-18
EP1961735B1 (en) 2009-11-18
PT1961735E (pt) 2009-12-21
IL200537A (en) 2013-03-24
CN101675028B (zh) 2013-01-30
HK1121735A1 (en) 2009-04-30
CN101675028A (zh) 2010-03-17

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