MX2009001814A - Derivados de 4-aminoquinazolina y metodos de uso de los mismos. - Google Patents

Info

Publication number

MX2009001814A

MX2009001814A MX2009001814A MX2009001814A MX2009001814A MX 2009001814 A MX2009001814 A MX 2009001814A MX 2009001814 A MX2009001814 A MX 2009001814A MX 2009001814 A MX2009001814 A MX 2009001814A MX 2009001814 A MX2009001814 A MX 2009001814A

Authority

MX

Mexico

Prior art keywords

compound

cancer

subject

carcinoma

mmol

Prior art date

2006-08-22

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• 238000000034 method Methods 0.000 title claims abstract description 75
• DRYRBWIFRVMRPV-UHFFFAOYSA-N quinazolin-4-amine Chemical class C1=CC=C2C(N)=NC=NC2=C1 DRYRBWIFRVMRPV-UHFFFAOYSA-N 0.000 title abstract description 5
• 150000001875 compounds Chemical class 0.000 claims abstract description 260
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• 150000003839 salts Chemical class 0.000 claims abstract description 28
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• 229910052805 deuterium Inorganic materials 0.000 claims description 51
• YZCKVEUIGOORGS-OUBTZVSYSA-N Deuterium Chemical compound [2H] YZCKVEUIGOORGS-OUBTZVSYSA-N 0.000 claims description 47
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• AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 claims description 15
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