MX2008015892A - Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacion de los mismos. - Google Patents

Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacion de los mismos.

Info

Publication number
MX2008015892A
MX2008015892A MX2008015892A MX2008015892A MX2008015892A MX 2008015892 A MX2008015892 A MX 2008015892A MX 2008015892 A MX2008015892 A MX 2008015892A MX 2008015892 A MX2008015892 A MX 2008015892A MX 2008015892 A MX2008015892 A MX 2008015892A
Authority
MX
Mexico
Prior art keywords
von willebrand
factor
willebrand factor
complex
concentrate
Prior art date
Application number
MX2008015892A
Other languages
English (en)
Inventor
Debart Pere Ristol
Tomas Maria Mercedes Faro
Nieto Juan Ignacio Jorquera
Original Assignee
Grifols Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39316136&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2008015892(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Grifols Sa filed Critical Grifols Sa
Publication of MX2008015892A publication Critical patent/MX2008015892A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

El procedimiento se caracteriza por la preparación de una solución de Factor von Willebrand o de complejo de Factor VIII/ Factor von Willebrand que contiene FVW a una concentración de hasta 12 UI FVWRCo/ml y una proporción entre Factor von Willebrand/ Factor VIII superior o igual a 0,4; y proceder a continuación a la nanofiltración de la solución preparada en a) mediante un filtro de tamaño de poro menor de 35 nanómetros.
MX2008015892A 2008-01-08 2008-12-11 Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacion de los mismos. MX2008015892A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200800021A ES2298096B1 (es) 2008-01-08 2008-01-08 Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos.

Publications (1)

Publication Number Publication Date
MX2008015892A true MX2008015892A (es) 2009-07-07

Family

ID=39316136

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008015892A MX2008015892A (es) 2008-01-08 2008-12-11 Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacion de los mismos.

Country Status (17)

Country Link
US (2) US8354505B2 (es)
EP (1) EP2078730B9 (es)
JP (1) JP4976366B2 (es)
CN (1) CN101480490B (es)
AR (1) AR072441A1 (es)
AT (1) ATE509031T1 (es)
AU (1) AU2008255137C1 (es)
BR (1) BRPI0900057B8 (es)
CA (1) CA2645701C (es)
CL (1) CL2009000022A1 (es)
ES (2) ES2298096B1 (es)
HK (1) HK1129075A1 (es)
MX (1) MX2008015892A (es)
NZ (1) NZ573400A (es)
PL (1) PL2078730T3 (es)
PT (1) PT2078730E (es)
RU (1) RU2417096C2 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861395B1 (fr) * 2003-10-23 2006-02-17 Lab Francais Du Fractionnement Facteur viii viralement securise a faible teneur en multimeres superieurs
BRPI0821474B8 (pt) * 2007-12-28 2021-05-25 Baxalta GmbH formulação farmacêutica líquida estável
US11197916B2 (en) 2007-12-28 2021-12-14 Takeda Pharmaceutical Company Limited Lyophilized recombinant VWF formulations
TWI508735B (zh) 2008-10-21 2015-11-21 巴克斯特國際公司 凍乾的重組ｖｗｆ調配物
HUE039317T2 (hu) * 2011-06-10 2018-12-28 Baxalta GmbH Koagulációs betegség kezelése rekombináns VWF adagolásával
ES2641042T3 (es) * 2011-06-24 2017-11-07 Asahi Kasei Kuraray Medical Co., Ltd. Procedimiento para la fabricación de un fármaco proteínico
PT2804623T (pt) 2012-01-12 2019-11-18 Bioverativ Therapeutics Inc Polipéptidos quiméricos do fator viii e suas utilizações
CN104411716B (zh) 2012-04-24 2018-09-07 诺和诺德股份有限公司 适用于治疗血友病的化合物
WO2015066769A1 (en) * 2013-11-08 2015-05-14 Csl Ltd. New method to concentrate von willebrand factor or complexes thereof
CN106414492B (zh) * 2014-06-06 2021-07-06 奥克塔法马股份有限公司 包含因子viii和冯·维勒布兰德因子肽的制剂
CN104804078B (zh) * 2015-05-05 2019-01-04 广东卫伦生物制药有限公司 人体血清凝血因子ⅷ中的病毒过滤方法
JP7253505B2 (ja) 2017-06-23 2023-04-06 武田薬品工業株式会社 第ｖｉｉｉ因子亜種の精製
CN110997015A (zh) * 2017-08-23 2020-04-10 德国杰特贝林生物制品有限公司 用于von Willebrand因子的病毒过滤的方法
EP4384205A1 (en) 2021-08-11 2024-06-19 Grifols Worldwide Operations Limited Method for producing human plasma-derived factor viii / von willebrand factor and composition obtained

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110907A (en) * 1989-08-01 1992-05-05 Alpha Therapeutic Corporation Factor viii complex purification using heparin affinity chromatography
US5288853A (en) * 1992-04-30 1994-02-22 Alpha Therapeutic Corporation Factor viii purification process
EP0860444A1 (en) * 1997-02-24 1998-08-26 Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis (CLB) Method for removing viruses from a protein solution
AT406373B (de) 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
AT405485B (de) 1997-05-28 1999-08-25 Immuno Ag Eine das vwf-propeptid enthaltende pharmazeutische präparation
FR2772381B1 (fr) * 1997-12-15 2001-06-08 Lab Francais Du Fractionnement Procede de preparation par filtration d'une solution de facteur viii securisee viralement
FR2861395B1 (fr) * 2003-10-23 2006-02-17 Lab Francais Du Fractionnement Facteur viii viralement securise a faible teneur en multimeres superieurs
FR2874216B1 (fr) 2004-08-16 2006-11-03 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur von willebrand (fvw) par voie chromatographique et concentre de fvw susceptible d'etre ainsi obtenu

Also Published As

Publication number Publication date
NZ573400A (en) 2010-02-26
AU2008255137A1 (en) 2009-07-23
AU2008255137C1 (en) 2015-08-27
CL2009000022A1 (es) 2009-11-20
EP2078730B1 (en) 2011-05-11
BRPI0900057B1 (pt) 2021-03-23
JP4976366B2 (ja) 2012-07-18
EP2078730B9 (en) 2011-12-21
RU2417096C2 (ru) 2011-04-27
ES2298096A1 (es) 2008-05-01
HK1129075A1 (en) 2009-11-20
ATE509031T1 (de) 2011-05-15
PL2078730T3 (pl) 2011-10-31
CA2645701C (en) 2013-09-17
RU2008151957A (ru) 2010-07-10
AU2008255137B2 (en) 2011-04-07
BRPI0900057A2 (pt) 2009-09-22
PT2078730E (pt) 2011-07-14
ES2363827T3 (es) 2011-08-17
CA2645701A1 (en) 2009-07-08
ES2298096B1 (es) 2009-01-01
CN101480490A (zh) 2009-07-15
CN101480490B (zh) 2013-05-29
US20090176709A1 (en) 2009-07-09
AR072441A1 (es) 2010-09-01
EP2078730A1 (en) 2009-07-15
BRPI0900057B8 (pt) 2021-06-29
JP2009161528A (ja) 2009-07-23
US20110275570A1 (en) 2011-11-10
US8354505B2 (en) 2013-01-15

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