MX2008012791A - Terapia de combinacion de (2r,z)-2-amino-2-ciclohexil-n-(5-(1-meti l-1h-pirazol-4-il)-1-oxo-2,6-dihidro-1h-[1,2]diazepinos[4,5,6-cd[ indol-8-il)acetamida. - Google Patents
Terapia de combinacion de (2r,z)-2-amino-2-ciclohexil-n-(5-(1-meti l-1h-pirazol-4-il)-1-oxo-2,6-dihidro-1h-[1,2]diazepinos[4,5,6-cd[ indol-8-il)acetamida.Info
- Publication number
- MX2008012791A MX2008012791A MX2008012791A MX2008012791A MX2008012791A MX 2008012791 A MX2008012791 A MX 2008012791A MX 2008012791 A MX2008012791 A MX 2008012791A MX 2008012791 A MX2008012791 A MX 2008012791A MX 2008012791 A MX2008012791 A MX 2008012791A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- oxo
- methyl
- cyclohexyl
- amino
- Prior art date
Links
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- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78927606P | 2006-04-04 | 2006-04-04 | |
| PCT/IB2007/000928 WO2007113671A1 (en) | 2006-04-04 | 2007-03-26 | Combination therapy of (2r,z)-2-amino-2-cyclohexyl-n-(5-(1-methyl-1h-pyrazol-4-yl)-1-oxo-2,6-dihydro-1h-[1,2]diazepino[4,5,6-cd]indol-8-yl)acetamide |
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| JPWO2009113436A1 (ja) * | 2008-03-14 | 2011-07-21 | 国立大学法人 千葉大学 | Ｆｇｆｒ３遺伝子阻害剤の放射線照射併用による放射線の抗癌作用増強法および副作用軽減法 |
| EP2258378A4 (en) * | 2008-03-27 | 2012-01-04 | Taiho Pharmaceutical Co Ltd | ANTICROBIAL AGENTS WITH A CYTIDINE DERIVATIVE AND CARBOPLATIN |
| KR101676062B1 (ko) * | 2009-04-11 | 2016-11-14 | 어레이 바이오파마 인크. | Ｄｎａ 손상제를 강화시키기 위한 체크포인트 키나제 1 억제제 |
| US8481557B2 (en) | 2009-04-11 | 2013-07-09 | Array Biopharma Inc. | Method of treatment using checkpoint kinase 1 inhibitors |
| CN108721284A (zh) | 2010-11-16 | 2018-11-02 | 阵列生物制药公司 | 检测点激酶1抑制剂和wee1激酶抑制剂的组合 |
| KR101716012B1 (ko) | 2011-12-31 | 2017-03-13 | 베이진 엘티디 | Parp 저해제로서의 융합된 테트라 또는 펜타-사이클릭 다이하이드로다이아제피노카르바졸론 |
| KR101684039B1 (ko) | 2011-12-31 | 2016-12-07 | 베이진 엘티디 | Parp 저해제로서의 융합된 테트라 또는 펜타-사이클릭 피리도프탈라지논 |
| AU2014293013A1 (en) | 2013-07-26 | 2016-03-17 | Race Oncology Ltd. | Combinatorial methods to improve the therapeutic benefit of bisantrene |
| EP3461480A1 (en) | 2017-09-27 | 2019-04-03 | Onxeo | Combination of a dna damage response cell cycle checkpoint inhibitors and belinostat for treating cancer |
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| SE9704545D0 (sv) * | 1997-12-05 | 1997-12-05 | Astra Pharma Prod | Novel compounds |
| EA009337B1 (ru) * | 2003-01-09 | 2007-12-28 | Пфайзер Инк. | Трициклические соединения, представляющие собой ингибиторы протеинкиназ, для увеличения эффективности противоопухолевых агентов и лучевой терапии |
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- 2007-03-26 EP EP07734247A patent/EP2007375A1/en not_active Withdrawn
- 2007-03-26 AU AU2007232279A patent/AU2007232279B2/en not_active Ceased
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| AU2007232279B2 (en) | 2010-05-06 |
| US20090312280A1 (en) | 2009-12-17 |
| AU2007232279A1 (en) | 2007-10-11 |
| RU2008139406A (ru) | 2010-04-10 |
| JP2007277240A (ja) | 2007-10-25 |
| RU2409361C2 (ru) | 2011-01-20 |
| TW200806301A (en) | 2008-02-01 |
| IL194340A0 (en) | 2009-08-03 |
| WO2007113671A1 (en) | 2007-10-11 |
| BRPI0709731A2 (pt) | 2011-07-26 |
| CN101415417A (zh) | 2009-04-22 |
| CA2648371A1 (en) | 2007-10-11 |
| KR20080100838A (ko) | 2008-11-19 |
| AR060284A1 (es) | 2008-06-04 |
| EP2007375A1 (en) | 2008-12-31 |
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