MX2007009222A - Moduladores de adam-9. - Google Patents
Moduladores de adam-9.Info
- Publication number
- MX2007009222A MX2007009222A MX2007009222A MX2007009222A MX2007009222A MX 2007009222 A MX2007009222 A MX 2007009222A MX 2007009222 A MX2007009222 A MX 2007009222A MX 2007009222 A MX2007009222 A MX 2007009222A MX 2007009222 A MX2007009222 A MX 2007009222A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- tumors
- kid24
- cell
- antibody
- Prior art date
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| US64978705P | 2005-02-02 | 2005-02-02 | |
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| EP2514767A1 (en) * | 2006-12-19 | 2012-10-24 | Ablynx N.V. | Amino acid sequences directed against a metalloproteinase from the ADAM family and polypeptides comprising the same for the treatment of ADAM-related diseases and disorders |
| AU2008207945A1 (en) | 2007-01-22 | 2008-07-31 | Macrogenics West, Inc. | Human cancer stem cells |
| EP3045475B1 (en) | 2008-04-02 | 2017-10-04 | MacroGenics, Inc. | Bcr-complex-specific antibodies and methods of using same |
| US20090285840A1 (en) * | 2008-04-29 | 2009-11-19 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Methods for treating pathological neovascularization |
| US9339560B2 (en) * | 2008-09-22 | 2016-05-17 | Hoffmann-La Roche Inc. | Method for determining the anti-tumor efficacy of monoclonal antibodies |
| SG10201407908VA (en) | 2008-12-19 | 2015-01-29 | Macrogenics Inc | Covalent diabodies and uses thereof |
| US20110306655A1 (en) * | 2009-02-19 | 2011-12-15 | Richard Antonius Jozef Janssen | Methods for identifying and compounds useful for the diagnosis and treatment of diseases involving inflammation |
| PH12012501751A1 (en) | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| NZ705128A (en) | 2010-03-04 | 2015-04-24 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| JP5964300B2 (ja) | 2010-08-02 | 2016-08-03 | マクロジェニクス，インコーポレーテッド | 共有結合型ダイアボディおよびその使用 |
| BR112013029892A2 (pt) | 2011-05-21 | 2016-12-20 | Macrogenics Inc | polipeptídeo, molécula de ligação a antígeno, diacorpo e uso de uma porção polipeptídica de uma proteína de ligação a soro desimunizada |
| US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
| TN2016000525A1 (en) | 2014-05-29 | 2018-04-04 | Macrogenics Inc | Tri-specific binding molecules and methods of use thereof |
| SG10202010506TA (en) | 2015-07-30 | 2020-11-27 | Macrogenics Inc | Pd-1-binding molecules and methods of use thereof |
| US10954301B2 (en) | 2015-12-14 | 2021-03-23 | Macrogenics, Inc. | Bispecific molecules having immunoreactivity with PD-1 and CTLA-4, and methods of use thereof |
| CA3020864A1 (en) | 2016-04-15 | 2017-10-19 | Macrogenics, Inc. | Novel b7-h3-binding molecules, antibody drug conjugates thereof and methods of use thereof |
| KR102630036B1 (ko) * | 2016-12-23 | 2024-01-29 | 마크로제닉스, 인크. | Adam9-결합 분자, 및 이것의 사용 방법 |
| CN110267685B (zh) * | 2016-12-23 | 2023-06-20 | 伊缪诺金公司 | 靶向adam9的免疫缀合物及其使用方法 |
| BR112019017628A2 (pt) | 2017-02-24 | 2020-07-07 | Macrogenics, Inc. | molécula de ligação a cd137 x ta, composições farmacêuticas, uso da molécula de ligação a cd137 x ta, molécula de ligação a cd137, uso da molécula de ligação a cd137, molécula de ligação a her2/neu, uso da molécula de ligação a her2/neu, e uso de uma composição |
| JP7448219B2 (ja) | 2017-10-02 | 2024-03-12 | ヴェラ セラピューティクス エルエルシー | Ａｄａｍ１０の生物学的活性を阻害するための方法および組成物 |
| US11795226B2 (en) | 2017-12-12 | 2023-10-24 | Macrogenics, Inc. | Bispecific CD16-binding molecules and their use in the treatment of disease |
| US12247232B2 (en) | 2018-01-31 | 2025-03-11 | Verra Therapeutics, Inc. | Methods and compositions for inhibiting ADAM 9 biological activities |
| EP3752196A4 (en) | 2018-02-15 | 2022-03-23 | MacroGenics, Inc. | CD3-BINDING DOMAIN VARIANTS AND THEIR USE IN COMBINATION THERAPIES FOR THE TREATMENT OF DISEASES |
| MX2020013466A (es) | 2018-06-26 | 2021-04-19 | Immunogen Inc | Inmunoconjugados dirigidos a adam9 y métodos para usarlos. |
| JP2024512392A (ja) * | 2021-03-08 | 2024-03-19 | イミュノジェン・インコーポレーテッド | がんの治療のためのａｄａｍ９を標的とする免疫抱合体の有効性を増加させるための方法 |
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2006
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- 2006-02-02 CN CN2006800087418A patent/CN101142236B/zh not_active Expired - Fee Related
- 2006-02-02 AU AU2006210589A patent/AU2006210589B2/en not_active Ceased
- 2006-02-02 US US11/346,779 patent/US7674619B2/en not_active Expired - Fee Related
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- 2006-02-02 JP JP2007554221A patent/JP5328155B2/ja not_active Expired - Fee Related
- 2006-02-02 NZ NZ556561A patent/NZ556561A/en not_active IP Right Cessation
- 2006-02-02 WO PCT/US2006/003748 patent/WO2006084075A2/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| CN101142236B (zh) | 2013-03-20 |
| JP2008529494A (ja) | 2008-08-07 |
| EP1841794A2 (en) | 2007-10-10 |
| WO2006084075A3 (en) | 2007-06-28 |
| JP5328155B2 (ja) | 2013-10-30 |
| AU2006210589A1 (en) | 2006-08-10 |
| KR20070102555A (ko) | 2007-10-18 |
| EP1841794B1 (en) | 2013-11-20 |
| CN101142236A (zh) | 2008-03-12 |
| KR101317358B1 (ko) | 2013-10-15 |
| AU2006210589B2 (en) | 2011-12-08 |
| EP1841794A4 (en) | 2008-10-29 |
| IL184657A (en) | 2012-06-28 |
| IL184657A0 (en) | 2007-12-03 |
| US20060172350A1 (en) | 2006-08-03 |
| US20100111951A1 (en) | 2010-05-06 |
| NZ556561A (en) | 2011-08-26 |
| CA2596273A1 (en) | 2006-08-10 |
| WO2006084075A2 (en) | 2006-08-10 |
| US7674619B2 (en) | 2010-03-09 |
| CA2596273C (en) | 2017-11-14 |
| HK1107359A1 (en) | 2008-04-03 |
| US8361475B2 (en) | 2013-01-29 |
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