MX2007000842A - Compuestos de insoindolina y metodos de su uso. - Google Patents
Compuestos de insoindolina y metodos de su uso.Info
- Publication number
- MX2007000842A MX2007000842A MX2007000842A MX2007000842A MX2007000842A MX 2007000842 A MX2007000842 A MX 2007000842A MX 2007000842 A MX2007000842 A MX 2007000842A MX 2007000842 A MX2007000842 A MX 2007000842A MX 2007000842 A MX2007000842 A MX 2007000842A
- Authority
- MX
- Mexico
- Prior art keywords
- inhibitor
- compound
- disease
- cancer
- administered
- Prior art date
Links
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US10/900,332 US7405237B2 (en) | 2004-07-28 | 2004-07-28 | Isoindoline compounds and methods of their use |
| PCT/US2005/026679 WO2006015060A2 (en) | 2004-07-28 | 2005-07-27 | Isoindoline compounds and methods of their use |
Publications (1)
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| MX2007000842A true MX2007000842A (es) | 2007-04-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| MX2007000842A MX2007000842A (es) | 2004-07-28 | 2005-07-27 | Compuestos de insoindolina y metodos de su uso. |
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| EP (1) | EP1781610A2 (enExample) |
| JP (1) | JP2008508298A (enExample) |
| KR (1) | KR20070047807A (enExample) |
| CN (1) | CN101031545A (enExample) |
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| WO (1) | WO2006015060A2 (enExample) |
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| BR0315316A (pt) * | 2002-10-15 | 2005-08-16 | Celgene Corp | Métodos de tratar, prevenir ou controlar uma sìndrome mielodisplásica, e de reduzir ou evitar um efeito adverso associado com a administração de um segundo ingrediente ativo em um paciente sofrendo de uma sìndrome mielodisplásica, composição farmacêutica, forma de dosagem unitária, e, kit |
| JP2006507324A (ja) * | 2002-11-06 | 2006-03-02 | セルジーン・コーポレーション | 骨髄増殖性疾患を治療および管理するための選択的サイトカイン阻害薬を含む組成物およびその使用法 |
| EP1744748A4 (en) * | 2004-04-14 | 2009-08-12 | Celgene Corp | METHOD FOR USE OF SELECTIVE CYTOKINE-INHIBITORY MEDICAMENTS AND COMPOSITIONS CONTAINING THEREOF FOR THE TREATMENT AND SUPPLY OF MYELODYSPLASTIC SYNDROMES |
| US7405237B2 (en) * | 2004-07-28 | 2008-07-29 | Celgene Corporation | Isoindoline compounds and methods of their use |
| US7244759B2 (en) * | 2004-07-28 | 2007-07-17 | Celgene Corporation | Isoindoline compounds and methods of making and using the same |
| EP1896007B1 (en) * | 2005-05-04 | 2014-03-19 | Medigene AG | Method of administering a cationic liposomal preparation comprising paclitexel |
| PT1907373E (pt) | 2005-06-30 | 2013-02-18 | Celgene Corp | Processos de preparação de compostos 4-amino-2-(2,6- dioxopiperidina-3-il)isoindolina-1,3-diona |
| US8168216B2 (en) | 2006-03-22 | 2012-05-01 | Medigene Ag | Treatment of triple receptor negative breast cancer |
| US20080064876A1 (en) * | 2006-05-16 | 2008-03-13 | Muller George W | Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione |
| TW200806625A (en) * | 2006-05-26 | 2008-02-01 | Astrazeneca Ab | Therapeutic compounds |
| US20090082368A1 (en) * | 2007-09-24 | 2009-03-26 | Painceptor Pharma Corporation | Methods of modulating neurotrophin-mediated activity |
| EA201171035A1 (ru) | 2009-02-10 | 2012-02-28 | Селджин Корпорейшн | Композиции, включающие модуляторы pde4, и способ их применения для лечения, профилактики и сопровождения туберкулеза |
| KR101695866B1 (ko) | 2009-05-12 | 2017-01-13 | 코닌클리케 필립스 엔.브이. | 전립선 암 마커로서의 포스포디에스테라제 9ａ |
| CN101580501B (zh) * | 2009-06-01 | 2011-03-09 | 南京卡文迪许生物工程技术有限公司 | 3-(取代二氢异吲哚酮-2-基)-2,6-哌啶二酮的合成方法及其中间体 |
| WO2011027326A1 (en) * | 2009-09-03 | 2011-03-10 | Ranbaxy Laboratories Limited | Process for the preparation of lenalidomide |
| GB2474120B (en) * | 2009-10-01 | 2011-12-21 | Amira Pharmaceuticals Inc | Compounds as Lysophosphatidic acid receptor antagonists |
| CN101747255B (zh) * | 2009-12-22 | 2011-11-23 | 上海大学 | 含烯炔结构的异吲哚酮类化合物及其合成方法 |
| LT3202461T (lt) | 2010-02-11 | 2019-04-25 | Celgene Corporation | Arilmetoksiizoindolino dariniai ir juos apimančios kompozicijos bei jų panaudojimo būdai |
| NZ603375A (en) | 2010-06-15 | 2014-10-31 | Celgene Corp | Biomarkers for the treatment of psoriasis |
| CN102603610B (zh) * | 2012-02-21 | 2014-07-09 | 四川大学 | 1,3-二氢-1-氧-2h-异吲哚类化合物、其制备方法和用途 |
| CN104045594B (zh) * | 2012-02-21 | 2016-08-17 | 四川大学 | 一类1,3-二氢-1-氧-2h-异吲哚类化合物及其用途 |
| KR101441096B1 (ko) * | 2012-11-27 | 2014-09-25 | 가톨릭대학교 산학협력단 | 제피티닙을 포함하는 톡소포자충 감염증의 예방 및 치료용 조성물 |
| TW201526897A (zh) | 2013-04-17 | 2015-07-16 | Signal Pharm Llc | 使用ｔｏｒ激酶抑制劑組合療法以治療癌症之方法 |
| CN104721820A (zh) * | 2013-12-24 | 2015-06-24 | 信达生物制药(苏州)有限公司 | 双特异性单克隆抗体在治疗葡萄膜炎中的用途 |
| US20170087129A1 (en) | 2014-05-16 | 2017-03-30 | Celgene Corporation | Compositions and methods for the treatment of atherosclerotic cardiovascular diseases with pde4 modulators |
| SG11201610746SA (en) * | 2014-07-08 | 2017-01-27 | Viiv Healthcare Uk Ltd | Isoindoline derivatives for use in the treatment of a viral infection |
| EP3324962A4 (en) | 2015-07-23 | 2018-12-19 | Temple University Of The Commonwealth System Of Higher Education | Novel aminothiazole compounds and methods using same |
| WO2017070291A1 (en) | 2015-10-21 | 2017-04-27 | Celgene Corporation | Pde4 modulators for treating and preventing immune reconstitution inflammatory syndrome (iris) |
| US10941126B2 (en) | 2017-01-19 | 2021-03-09 | Temple University-Of The Commonwealth System Of Higher Education | Bridged bicycloalkyl-substituted aminothiazoles and their methods of use |
| CA3072735A1 (en) | 2017-08-21 | 2019-02-28 | Celgene Corporation | Processes for the preparation of (s)-tert-butyl 4,5-diamino-5-oxopentanoate |
| KR102277626B1 (ko) * | 2018-08-16 | 2021-07-15 | 한국화학연구원 | 이소인돌린-1온 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 |
| CA3165475A1 (en) * | 2019-12-26 | 2021-07-01 | Ohio State Innovation Foundation | Methods and compositions for inhibition of dihydroorotate dehydrogenase in combination with an anti-cd38 therapeutic agent |
| CN114644586A (zh) * | 2022-04-12 | 2022-06-21 | 江苏豪森药业集团有限公司 | 一种来那度胺有关物质的制备方法 |
| WO2025118133A1 (zh) * | 2023-12-05 | 2025-06-12 | 浙江普洛家园药业有限公司 | 一种(s)-来那度胺-5-位衍生物及其合成方法和应用 |
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| EP1035848B1 (en) | 1997-07-31 | 2003-04-23 | Celgene Corporation | Substituted alkanohydroxamic acids and method of reducing tnf-alpha levels |
| ES2250121T3 (es) * | 1999-03-18 | 2006-04-16 | Celgene Corporation | 1-oxo- y 1,3-dioxoisoindolinas y su empleo en composiciones farmaceuticas para la reduccion de niveles de las citocinas inflamatorias. |
| US6326388B1 (en) | 1999-12-21 | 2001-12-04 | Celgene Corporation | Substituted 1,3,4-oxadiazoles and a method of reducing TNF-alpha level |
| AU2002323063B2 (en) | 2001-08-06 | 2007-11-08 | Entremed, Inc. | Synthesis and anti-tumor activity of nitrogen substituted thalidomide analogs |
| US7405237B2 (en) * | 2004-07-28 | 2008-07-29 | Celgene Corporation | Isoindoline compounds and methods of their use |
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2009
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| US7816393B2 (en) | 2010-10-19 |
| US20060025457A1 (en) | 2006-02-02 |
| US20090291991A1 (en) | 2009-11-26 |
| AU2005269367A1 (en) | 2006-02-09 |
| WO2006015060A3 (en) | 2006-07-20 |
| BRPI0513836A (pt) | 2008-05-20 |
| IL180978A0 (en) | 2007-07-04 |
| EP1781610A2 (en) | 2007-05-09 |
| KR20070047807A (ko) | 2007-05-07 |
| CA2574966A1 (en) | 2006-02-09 |
| CN101031545A (zh) | 2007-09-05 |
| ZA200701660B (en) | 2008-09-25 |
| US20080145336A1 (en) | 2008-06-19 |
| US7405237B2 (en) | 2008-07-29 |
| US7569597B2 (en) | 2009-08-04 |
| NZ553029A (en) | 2010-12-24 |
| WO2006015060A2 (en) | 2006-02-09 |
| JP2008508298A (ja) | 2008-03-21 |
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