MX2007000842A - Compuestos de insoindolina y metodos de su uso. - Google Patents
Compuestos de insoindolina y metodos de su uso.Info
- Publication number
- MX2007000842A MX2007000842A MX2007000842A MX2007000842A MX2007000842A MX 2007000842 A MX2007000842 A MX 2007000842A MX 2007000842 A MX2007000842 A MX 2007000842A MX 2007000842 A MX2007000842 A MX 2007000842A MX 2007000842 A MX2007000842 A MX 2007000842A
- Authority
- MX
- Mexico
- Prior art keywords
- inhibitor
- compound
- disease
- cancer
- administered
- Prior art date
Links
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US10/900,332 US7405237B2 (en) | 2004-07-28 | 2004-07-28 | Isoindoline compounds and methods of their use |
| PCT/US2005/026679 WO2006015060A2 (en) | 2004-07-28 | 2005-07-27 | Isoindoline compounds and methods of their use |
Publications (1)
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| MX2007000842A true MX2007000842A (es) | 2007-04-17 |
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| MX2007000842A MX2007000842A (es) | 2004-07-28 | 2005-07-27 | Compuestos de insoindolina y metodos de su uso. |
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| US7842691B2 (en) * | 2002-10-15 | 2010-11-30 | Celgene Corporation | Method for the treatment of myelodysplastic syndromes using cyclopropanecarboxylic acid {2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-OXO-2,3-dihydro-1 H-isoindol-4-yl}-amide |
| US20060165649A1 (en) * | 2002-11-06 | 2006-07-27 | Zeldis Jerome B | Methods of using and compositions comprising selective cytokine inhibitory drugs for the treatment and management of myeloproliferative diseases |
| CN1972686A (zh) * | 2004-04-14 | 2007-05-30 | 细胞基因公司 | 选择性细胞因子抑制药在髓发育不良综合征中的用途 |
| US7405237B2 (en) * | 2004-07-28 | 2008-07-29 | Celgene Corporation | Isoindoline compounds and methods of their use |
| US7244759B2 (en) * | 2004-07-28 | 2007-07-17 | Celgene Corporation | Isoindoline compounds and methods of making and using the same |
| US9233094B2 (en) * | 2005-05-04 | 2016-01-12 | Medigene Ag | Method of administering a cationic liposomal preparation |
| JP5366544B2 (ja) | 2005-06-30 | 2013-12-11 | セルジーン コーポレイション | ４−アミノ−２−（２，６−ジオキソピペリジン−３−イル）イソインドリン−１，３−ジオン化合物を調製するための方法 |
| AU2007228984B2 (en) | 2006-03-22 | 2012-05-03 | Syncore Biotechnology Co., Ltd | Treatment of triple receptor negative breast cancer |
| US20080064876A1 (en) * | 2006-05-16 | 2008-03-13 | Muller George W | Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione |
| TW200806625A (en) * | 2006-05-26 | 2008-02-01 | Astrazeneca Ab | Therapeutic compounds |
| US20090082368A1 (en) * | 2007-09-24 | 2009-03-26 | Painceptor Pharma Corporation | Methods of modulating neurotrophin-mediated activity |
| MY160002A (en) | 2009-02-10 | 2017-02-15 | Celgene Corp | Methods of using and compositions comprising pde4 modulators for treatment, prevention and management of tuberculosis |
| WO2010131193A1 (en) * | 2009-05-12 | 2010-11-18 | Koninklijke Philips Electronics N.V. | Phosphodiesterase 9a as prostate cancer marker |
| CN101580501B (zh) * | 2009-06-01 | 2011-03-09 | 南京卡文迪许生物工程技术有限公司 | 3-(取代二氢异吲哚酮-2-基)-2,6-哌啶二酮的合成方法及其中间体 |
| AU2010290822A1 (en) * | 2009-09-03 | 2012-03-29 | Ranbaxy Laboratories Limited | Process for the preparation of lenalidomide |
| GB2474120B (en) * | 2009-10-01 | 2011-12-21 | Amira Pharmaceuticals Inc | Compounds as Lysophosphatidic acid receptor antagonists |
| CN101747255B (zh) * | 2009-12-22 | 2011-11-23 | 上海大学 | 含烯炔结构的异吲哚酮类化合物及其合成方法 |
| SG10201501062SA (en) | 2010-02-11 | 2015-04-29 | Celgene Corp | Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same |
| CN103026229B (zh) | 2010-06-15 | 2016-03-30 | 细胞基因公司 | 用于治疗银屑病的生物标志物 |
| CN102603610B (zh) * | 2012-02-21 | 2014-07-09 | 四川大学 | 1,3-二氢-1-氧-2h-异吲哚类化合物、其制备方法和用途 |
| CN104045594B (zh) * | 2012-02-21 | 2016-08-17 | 四川大学 | 一类1,3-二氢-1-氧-2h-异吲哚类化合物及其用途 |
| KR101441096B1 (ko) * | 2012-11-27 | 2014-09-25 | 가톨릭대학교 산학협력단 | 제피티닙을 포함하는 톡소포자충 감염증의 예방 및 치료용 조성물 |
| EP2986318A1 (en) | 2013-04-17 | 2016-02-24 | Signal Pharmaceuticals, LLC | Combination therapy comprising a tor kinase inhibitor and an imid compound for treating cancer |
| CN104721820A (zh) * | 2013-12-24 | 2015-06-24 | 信达生物制药(苏州)有限公司 | 双特异性单克隆抗体在治疗葡萄膜炎中的用途 |
| US20170087129A1 (en) | 2014-05-16 | 2017-03-30 | Celgene Corporation | Compositions and methods for the treatment of atherosclerotic cardiovascular diseases with pde4 modulators |
| LT3166925T (lt) * | 2014-07-08 | 2018-06-11 | Viiv Healthcare Uk Limited | Izoindolino dariniai, skirti panaudoti virusinės infekcijos gydymui |
| WO2017015484A1 (en) | 2015-07-23 | 2017-01-26 | Temple University-Of The Commonwealth System Of Higher Education | Novel aminothiazole compounds and methods using same |
| WO2017070291A1 (en) | 2015-10-21 | 2017-04-27 | Celgene Corporation | Pde4 modulators for treating and preventing immune reconstitution inflammatory syndrome (iris) |
| WO2018136766A1 (en) * | 2017-01-19 | 2018-07-26 | Temple University-Of The Commonwealth System Of Higher Education | Novel bridged bicycloalkyl-substituted aminothizoles and their methods of use |
| WO2019040109A1 (en) | 2017-08-21 | 2019-02-28 | Celgene Corporation | PROCESSES FOR THE PREPARATION OF (S) -TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE |
| EP3838898B1 (en) * | 2018-08-16 | 2023-06-07 | Korea Research Institute of Chemical Technology | Isoindolin-1-one derivative, method for preparing the same, and pharmaceutical composition comprising the same as an effective component for preventing or treating cancer |
| AU2020412805A1 (en) * | 2019-12-26 | 2022-07-14 | Hendrix College | Methods and compositions for inhibition of dihydroorotate dehydrogenase in combination with an anti-CD38 therapeutic agent |
| CN114644586A (zh) * | 2022-04-12 | 2022-06-21 | 江苏豪森药业集团有限公司 | 一种来那度胺有关物质的制备方法 |
| WO2025118133A1 (zh) * | 2023-12-05 | 2025-06-12 | 浙江普洛家园药业有限公司 | 一种(s)-来那度胺-5-位衍生物及其合成方法和应用 |
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| JP2001511448A (ja) | 1997-07-31 | 2001-08-14 | セルジーン コーポレイション | 置換アルカノヒドロキサム酸およびＴＮＦαレベルの減少方法 |
| CA2361806C (en) * | 1999-03-18 | 2012-03-13 | Celgene Corporation | Substituted 1-oxo- and 1,3-dioxoisoindolines and their use in pharmaceutical compositions for reducing inflammatory cytokine levels |
| US6326388B1 (en) * | 1999-12-21 | 2001-12-04 | Celgene Corporation | Substituted 1,3,4-oxadiazoles and a method of reducing TNF-alpha level |
| NZ531294A (en) | 2001-08-06 | 2005-11-25 | Childrens Medical Center | Synthesis and anti-tumor activity of nitrogen substituted thalidomide analogs |
| US7405237B2 (en) * | 2004-07-28 | 2008-07-29 | Celgene Corporation | Isoindoline compounds and methods of their use |
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| CN101031545A (zh) | 2007-09-05 |
| US7569597B2 (en) | 2009-08-04 |
| US7816393B2 (en) | 2010-10-19 |
| IL180978A0 (en) | 2007-07-04 |
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| AU2005269367B2 (en) | 2011-12-01 |
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| US7405237B2 (en) | 2008-07-29 |
| CA2574966A1 (en) | 2006-02-09 |
| BRPI0513836A (pt) | 2008-05-20 |
| US20060025457A1 (en) | 2006-02-02 |
| US20090291991A1 (en) | 2009-11-26 |
| ZA200701660B (en) | 2008-09-25 |
| WO2006015060A3 (en) | 2006-07-20 |
| JP2008508298A (ja) | 2008-03-21 |
| KR20070047807A (ko) | 2007-05-07 |
| AU2005269367A1 (en) | 2006-02-09 |
| US20080145336A1 (en) | 2008-06-19 |
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