MEP8409A - Fuzionisana heterociklična jedinjenja - Google Patents

Fuzionisana heterociklična jedinjenja

Info

Publication number
MEP8409A
MEP8409A MEP-84/09A MEP8409A MEP8409A ME P8409 A MEP8409 A ME P8409A ME P8409 A MEP8409 A ME P8409A ME P8409 A MEP8409 A ME P8409A
Authority
ME
Montenegro
Prior art keywords
optionally
atom
optionally substituted
ring structure
heterocyclic compound
Prior art date
Application number
MEP-84/09A
Other languages
English (en)
Inventor
Tomoyasu Ishikawa
Hiroshi Banno
Masaki Seto
Takahiko Taniguchi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of MEP8409A publication Critical patent/MEP8409A/bs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Predstavljeni pronalazak se odnosi na jedinjenja predstavljeno formulom: Gdje je W jednako CX(R1) ili N, svako A je izabrano supsti tuisana aril grupa ili heteroaril grupa, X1 je –NR3-Y1-,-O-,-S-,-SO-,-SO2 ili –CHR3-gdje je R3 je izborno vezan za A tako da formira izborno supsti tuisanu strukturu prstena, R1je atom vodonika ili izborno supsti tuisana grupa vezana preko atoma ugljenika, atoma azota ili atoma kisjeonika, R2 je atom vodeonika ili izborno supsti tuisana grupa vezana preko atoma ugljenika ili atoma sumpora, ili R1 i R2, ili R2 i R3 su izborno vezani tako da formiraju izborno supsti tuisanu strukturu prstena, ili njegovu so, i inhibitor ti rozin kinaze ili sredstvo za profi laksu ili liječenje kancera, koje sadrži ovo jedinjenje ili njegov prolijek.
MEP-84/09A 2004-06-02 2005-06-01 Fuzionisana heterociklična jedinjenja MEP8409A (bs)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004165050 2004-06-02
JP2005058231 2005-03-02
PCT/JP2005/010451 WO2005118588A1 (ja) 2004-06-02 2005-06-01 縮合複素環化合物

Publications (1)

Publication Number Publication Date
MEP8409A true MEP8409A (bs) 2011-12-20

Family

ID=35462874

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-84/09A MEP8409A (bs) 2004-06-02 2005-06-01 Fuzionisana heterociklična jedinjenja

Country Status (18)

Country Link
US (4) US7507740B2 (bs)
EP (1) EP1752457B1 (bs)
JP (2) JP4134227B2 (bs)
KR (1) KR101194622B1 (bs)
AU (1) AU2005250285B2 (bs)
BR (1) BRPI0511768A (bs)
CA (1) CA2569016C (bs)
CR (1) CR8827A (bs)
GE (1) GEP20105024B (bs)
IL (1) IL179414A (bs)
MA (1) MA28973B1 (bs)
ME (1) MEP8409A (bs)
MX (1) MXPA06013996A (bs)
NO (1) NO20066015L (bs)
NZ (1) NZ551938A (bs)
RU (1) RU2389731C2 (bs)
TW (1) TWI392679B (bs)
WO (1) WO2005118588A1 (bs)

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Also Published As

Publication number Publication date
CA2569016A1 (en) 2005-12-15
RU2006147267A (ru) 2008-07-20
US7507740B2 (en) 2009-03-24
AU2005250285A1 (en) 2005-12-15
JPWO2005118588A1 (ja) 2008-04-03
JP4937172B2 (ja) 2012-05-23
CR8827A (es) 2007-04-20
IL179414A (en) 2013-11-28
MA28973B1 (fr) 2007-11-01
EP1752457A4 (en) 2010-05-26
EP1752457A1 (en) 2007-02-14
TW200611907A (en) 2006-04-16
EP1752457B1 (en) 2014-03-19
NZ551938A (en) 2010-07-30
BRPI0511768A (pt) 2008-01-08
AU2005250285B2 (en) 2011-08-18
RU2389731C2 (ru) 2010-05-20
NO20066015L (no) 2007-02-13
JP4134227B2 (ja) 2008-08-20
TWI392679B (zh) 2013-04-11
US20090029973A1 (en) 2009-01-29
US20070244132A1 (en) 2007-10-18
MXPA06013996A (es) 2007-02-08
US20090018335A1 (en) 2009-01-15
KR101194622B1 (ko) 2012-10-29
IL179414A0 (en) 2007-05-15
GEP20105024B (en) 2010-06-25
CA2569016C (en) 2012-11-27
US20090203717A1 (en) 2009-08-13
US8178543B2 (en) 2012-05-15
WO2005118588A1 (ja) 2005-12-15
JP2008247907A (ja) 2008-10-16
KR20070026695A (ko) 2007-03-08

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