MEP32308A - Pharmaceutical composition containing histone deacetylase inhibitor - Google Patents

Pharmaceutical composition containing histone deacetylase inhibitor

Info

Publication number
MEP32308A
MEP32308A MEP-323/08A MEP32308A MEP32308A ME P32308 A MEP32308 A ME P32308A ME P32308 A MEP32308 A ME P32308A ME P32308 A MEP32308 A ME P32308A
Authority
ME
Montenegro
Prior art keywords
histone deacetylase
deacetylase inhibitor
pharmaceutical composition
composition containing
containing histone
Prior art date
Application number
MEP-323/08A
Other languages
Bosnian (bs)
English (en)
Croatian (hr)
Inventor
Osamu Nakanishi
Tatsuo Sugawara
Hideyuki Migita
Yasuhiro Matsuba
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of MEP32308A publication Critical patent/MEP32308A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
MEP-323/08A 2003-05-26 2004-05-26 Pharmaceutical composition containing histone deacetylase inhibitor MEP32308A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2003148073 2003-05-26
PCT/JP2004/007562 WO2004103369A1 (en) 2003-05-26 2004-05-26 Pharmaceutical composition containing histone deacetylase inhibitor
YUP-2005/0884A RS20050884A (en) 2003-05-26 2004-05-26 Pharmaceutical composition containing histone deacetylase inhibitor

Publications (1)

Publication Number Publication Date
MEP32308A true MEP32308A (en) 2010-10-10

Family

ID=33475383

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-323/08A MEP32308A (en) 2003-05-26 2004-05-26 Pharmaceutical composition containing histone deacetylase inhibitor

Country Status (27)

Country Link
US (1) US20070098816A1 (ru)
EP (1) EP1626719A1 (ru)
JP (1) JP2006526031A (ru)
KR (1) KR100938712B1 (ru)
CN (2) CN1794991A (ru)
AR (1) AR045318A1 (ru)
AU (1) AU2004241873C1 (ru)
BR (1) BRPI0410959A (ru)
CA (4) CA2634766A1 (ru)
CL (1) CL2004001278A1 (ru)
CO (1) CO5660262A2 (ru)
CR (1) CR8163A (ru)
CU (1) CU23490B7 (ru)
EC (1) ECSP056253A (ru)
IL (1) IL171941A0 (ru)
ME (1) MEP32308A (ru)
MX (1) MXPA05012345A (ru)
NO (1) NO20055417L (ru)
NZ (1) NZ543591A (ru)
PE (1) PE20050206A1 (ru)
RS (1) RS20050884A (ru)
RU (1) RU2322971C2 (ru)
TW (1) TW200505424A (ru)
UA (1) UA81499C2 (ru)
UY (1) UY28330A1 (ru)
WO (1) WO2004103369A1 (ru)
ZA (1) ZA200509515B (ru)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6777217B1 (en) 1996-03-26 2004-08-17 President And Fellows Of Harvard College Histone deacetylases, and uses related thereto
US20030129724A1 (en) 2000-03-03 2003-07-10 Grozinger Christina M. Class II human histone deacetylases, and uses related thereto
US7244853B2 (en) 2001-05-09 2007-07-17 President And Fellows Of Harvard College Dioxanes and uses thereof
ES2425083T3 (es) * 2003-09-25 2013-10-11 Astellas Pharma Inc. Agente antitumoral que comprende FK228 como inhibidor de histona desacetilasa y doxorrubicina como inhibidor de topoisomerasa II
EP1712552A1 (en) * 2005-04-11 2006-10-18 INDENA S.p.A. Semisynthesis process for the preparation of 10-deacetyl-n-debenzoyl-paclitaxel
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
AU2006223086A1 (en) * 2005-03-11 2006-09-21 The Regents Of The University Of Colorado Histone deacetylase inhibitors sensitize cancer cells to epidermal growth factor inhibitors
SG171690A1 (en) 2005-03-22 2011-06-29 Harvard College Treatment of protein degradation disorders
JP2009501236A (ja) 2005-07-14 2009-01-15 タケダ サン ディエゴ インコーポレイテッド ヒストンデアセチラーゼ阻害剤
WO2008091349A1 (en) 2006-02-14 2008-07-31 The President And Fellows Of Harvard College Bifunctional histone deacetylase inhibitors
AU2007214458C1 (en) 2006-02-14 2012-12-06 Dana-Farber Cancer Institute, Inc. Histone deacetylase inhibitors
AU2007248656B2 (en) 2006-05-03 2013-04-04 Dana-Farber Cancer Institute, Inc. Histone deacetylase and tubulin deacetylase inhibitors
GB0625283D0 (en) * 2006-12-19 2007-01-24 Cyclacel Ltd Combination
RU2446796C2 (ru) 2006-12-26 2012-04-10 Фармасайкликс, Инк. Способ использования ингибиторов гистондеацетилазы и мониторинга биомаркеров в комбинированной терапии
WO2009067453A1 (en) * 2007-11-19 2009-05-28 Syndax Pharmaceuticals, Inc. Combinations of hdac inhibitors and proteasome inhibitors
CA2709383A1 (en) * 2007-12-14 2009-06-25 Milton L. Brown Histone deacetylase inhibitors
KR101708946B1 (ko) 2008-07-23 2017-02-21 다나-파버 캔서 인스티튜트 인크. 탈아세틸화제 억제제 및 그것의 용도
GB2462893B (en) * 2008-08-29 2010-10-13 Bayer Schering Pharma Ag N-(2-aminophenyl)-4-[N-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (MS-275) polymorph B
PE20110677A1 (es) * 2008-08-29 2011-09-16 Bayer Ip Gmbh Polimorfo b de la n-(2-aminofenil)-4-[n-(piridin-3-il) metoxicarbonilamino-metil]benzamida (ms-275)
CN102300862B (zh) 2008-12-19 2016-11-23 沃泰克斯药物股份有限公司 用作atr激酶抑制剂的化合物
EP2395972A4 (en) * 2009-02-11 2014-02-12 Liangping Yu PARTICULATE COMPOSITION AND METHOD FOR PRODUCING THE SAME
CN102573826A (zh) * 2009-05-01 2012-07-11 奥克兹美制药公司 用于治疗癌症的喷他脒组合
CA2763786C (en) * 2009-06-08 2014-09-30 Gilead Sciences, Inc. Alkanoylamino benzamide aniline hdac inihibitor compounds
WO2011019393A2 (en) 2009-08-11 2011-02-17 President And Fellows Of Harvard College Class- and isoform-specific hdac inhibitors and uses thereof
IN2012DN02018A (ru) * 2009-08-25 2015-07-31 Abraxis Bioscience Llc
NZ603477A (en) 2010-05-12 2014-09-26 Vertex Pharma Compounds useful as inhibitors of atr kinase
MX365393B (es) 2011-09-13 2019-05-31 Pharmacyclics Llc Formulaciones de inhibidor de histona deacetilasa en combinación con bendamustina y usos de las mismas.
EP2940017B1 (en) 2011-09-30 2019-08-28 Vertex Pharmaceuticals Incorporated Process for making compounds useful as inhibitors of ATR kinase
MX2014003785A (es) * 2011-09-30 2014-07-24 Vertex Phamaceuticals Inc Tratamiento del cancer de pancreas y del cancer de pulmon de celulas no pequeñas con inhibidores de atr.
WO2013085902A1 (en) * 2011-12-05 2013-06-13 The University Of Texas M.D. Combination therapy methods for treating an inflammatory breast cancer
NZ720511A (en) 2012-04-05 2016-12-23 Vertex Pharma Compounds useful as inhibitors of atr kinase and combination therapies thereof
DK2904406T3 (en) 2012-10-04 2018-06-18 Vertex Pharma METHOD OF DETERMINING THE ATR INHIBITION, INCREASED DNA DAMAGE
JP6320506B2 (ja) 2013-03-12 2018-05-09 セルジーン クオンティセル リサーチ，インク． ヒストンデメチラーゼ阻害剤
US9963452B2 (en) * 2013-03-14 2018-05-08 Augusta Pharmaceuticals Inc. Methods, compounds, and compositions for inhibition of ROS
WO2015127227A1 (en) * 2014-02-21 2015-08-27 Cleveland Biolabs, Inc. Uses of flagellin for improved chemotherapy
US9758517B2 (en) 2014-09-17 2017-09-12 Celgene Quanticel Research, Inc. Histone demethylase inhibitors
WO2017059357A1 (en) 2015-09-30 2017-04-06 Vertex Pharmaceuticals Incorporated Method for treating cancer using a combination of dna damaging agents and atr inhibitors
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
US11596612B1 (en) 2022-03-08 2023-03-07 PTC Innovations, LLC Topical anesthetics

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
US6794392B1 (en) * 1996-09-30 2004-09-21 Schering Aktiengesellschaft Cell differentiation inducer
JP3354090B2 (ja) 1996-09-30 2002-12-09 シエーリング アクチエンゲゼルシャフト 分化誘導剤
US6174905B1 (en) * 1996-09-30 2001-01-16 Mitsui Chemicals, Inc. Cell differentiation inducer
US5753637A (en) * 1996-10-09 1998-05-19 Ideal Ideas, Inc. Method of treating acne conditions
NZ510504A (en) * 1998-09-25 2003-09-26 Warner Lambert Co Chemotherapy of cancer with acetyldinaline in combination with gemcitabine, capecitabine or cisplatin
AU4144400A (en) * 1999-04-27 2000-11-10 Mitsubishi Pharma Corporation Preventives/remedies for liver diseases
EP1229916A2 (en) * 1999-11-10 2002-08-14 Warner-Lambert Company Combination chemotherapy
US6905669B2 (en) * 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
CZ20022216A3 (cs) * 2001-07-02 2003-05-14 Warner-Lambert Company Kombinační chemoterapie
JP2003137866A (ja) * 2001-11-01 2003-05-14 Sankyo Co Ltd フェニレンジアミン誘導体

Also Published As

Publication number Publication date
KR20060009371A (ko) 2006-01-31
EP1626719A1 (en) 2006-02-22
MXPA05012345A (es) 2006-02-08
CA2634709A1 (en) 2004-12-02
CA2634765A1 (en) 2004-12-02
WO2004103369A1 (en) 2004-12-02
JP2006526031A (ja) 2006-11-16
KR100938712B1 (ko) 2010-01-25
RS20050884A (en) 2008-04-04
ECSP056253A (es) 2006-10-25
CN101322707A (zh) 2008-12-17
CR8163A (es) 2006-07-14
AU2004241873C1 (en) 2009-01-22
CU23490B7 (es) 2010-02-23
RU2322971C2 (ru) 2008-04-27
RU2005140570A (ru) 2006-06-10
ZA200509515B (en) 2006-07-26
CO5660262A2 (es) 2006-07-31
AR045318A1 (es) 2005-10-26
NO20055417D0 (no) 2005-11-16
UA81499C2 (en) 2008-01-10
PE20050206A1 (es) 2005-03-26
AU2004241873B8 (en) 2008-05-29
AU2004241873A1 (en) 2004-12-02
IL171941A0 (en) 2006-04-10
UY28330A1 (es) 2004-12-31
CN1794991A (zh) 2006-06-28
US20070098816A1 (en) 2007-05-03
CA2527191A1 (en) 2004-12-02
AU2004241873B2 (en) 2008-05-08
TW200505424A (en) 2005-02-16
NZ543591A (en) 2009-09-25
CL2004001278A1 (es) 2005-05-06
BRPI0410959A (pt) 2006-07-04
CA2634766A1 (en) 2004-12-02
NO20055417L (no) 2005-12-19

Similar Documents

Publication Publication Date Title
MEP32308A (en) Pharmaceutical composition containing histone deacetylase inhibitor
NO20055216D0 (no) Nye hydroksamater som terapeutiske midler
ECSP20027480A (es) Indolil alquil amino derivados sustituidos como nuevos inhibidores de la histona desacetilasa
BRPI0410727A (pt) composto, composição farmacêutica, e, uso de um composto
NO20044135L (no) Piperazinyl-, piperidinyl- og morfolinylderivater som nye inhibitorer av histon-deacetylase
CY1126110T1 (el) Παραγωγα βενζοϋδροξαμικου οξεος ως εκλεκτικοι αναστολε1σ του hdac6
EA200401200A1 (ru) Карбониламинопроизводные как новые ингибиторы гистондеацетилазы
EA200700143A1 (ru) Производные замещенного пропенилпиперазина в качестве новых ингибиторов гистондеацетилазы
NO20044444L (no) Benzamidderivater nyttige som histondeacetylase inhibitorer
NO20044194L (no) Nye inhibitorer av histon-deacetylase
ME00566A (en) Oral dosage form containing a pde 4 inhibitor as an active ingredient and polyvinylpyrrolidon as excipient
AR042851A1 (es) Acidos hidroxamicos inhibidores de histona desacetilasa
EA200701970A1 (ru) Гидроксаматы как ингибиторы гистондеацетилазы и содержащие их фармацевтические композиции
AR117655A1 (es) Composición farmacéutica para administración oral que comprende derivado de aminopirimidina o su sal
MX342041B (es) Formulacion farmaceutica para inhibidores de histona desacetilasa.
SV2006002109A (es) Una composicion farmaceutica antimicobacteriana
PT4110781T (pt) Compostos derivados de 1,3,4-oxadiazol como inibidor de histona desacetilase 6 e a composição farmacêutica compreendendo os mesmos
EP4110780A4 (en) COMPOUNDS DERIVED FROM 1,3,4-OXADIAZOLE USED AS HISTONE DEACETYLASE 6 INHIBITORS, AND PHARMACEUTICAL COMPOSITION COMPRISING THEM
MX2008008470A (es) Nuevos derivados pirrolicos con actividad inhibidora de desacetilasa de histonas.
EP4136085A4 (en) 1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE-6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS THEREOF
EA201992296A1 (ru) Производные хиноксалина и пиридопиразина в качестве ингибиторов pi3k-бета
TH81162A (th) สารผสมทางเภสัชกรรมที่มีตัวยับยั้งฮิสโตนดีอะซีทิลเลส
PE20212078A1 (es) Inhibidor de mpges 1 para el tratamiento de dolor de osteoartritis
TH81162B (th) สารผสมทางเภสัชกรรมที่มีตัวยับยั้งฮิสโตนดีอะซีทิลเลส
PE20040532A1 (es) Formulacion medicamentosa a base de fexofenadina