ME01521B - Antibakterijski kinolinski derivati - Google Patents
Antibakterijski kinolinski derivatiInfo
- Publication number
- ME01521B ME01521B MEP-2013-43A MEP4313A ME01521B ME 01521 B ME01521 B ME 01521B ME P4313 A MEP4313 A ME P4313A ME 01521 B ME01521 B ME 01521B
- Authority
- ME
- Montenegro
- Prior art keywords
- quinoline derivatives
- antibacterial quinoline
- antibacterial
- solubles
- oxides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Abstract
Ovaj pronalazak se odnosi na nove supstituisane kinolinske derivate u skladu sa formulom (Ia) ili (Ib): uključujući njihove bilo koje stereohemijske izomerne forme, njihove N -okside, farmaceutski prihvatljive soli ili rastvorljive materije.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06125510 | 2006-12-06 | ||
PCT/EP2007/063314 WO2008068268A1 (en) | 2006-12-06 | 2007-12-04 | Antibacterial quinoline derivatives |
EP07847812A EP2099760B1 (en) | 2006-12-06 | 2007-12-04 | Antibacterial quinoline derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ME01521B true ME01521B (me) | 2014-04-20 |
Family
ID=37909392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2013-43A ME01521B (me) | 2006-12-06 | 2007-12-04 | Antibakterijski kinolinski derivati |
Country Status (32)
Country | Link |
---|---|
US (1) | US8293732B2 (me) |
EP (1) | EP2099760B1 (me) |
JP (1) | JP5466012B2 (me) |
KR (3) | KR101574642B1 (me) |
CN (1) | CN101547905B (me) |
AP (1) | AP2670A (me) |
AR (1) | AR064147A1 (me) |
BR (1) | BRPI0719939B8 (me) |
CA (1) | CA2668517C (me) |
CL (1) | CL2007003515A1 (me) |
CY (1) | CY1114384T1 (me) |
DK (1) | DK2099760T3 (me) |
EA (1) | EA022344B1 (me) |
ES (1) | ES2407824T3 (me) |
HK (1) | HK1137433A1 (me) |
HR (1) | HRP20130372T1 (me) |
IL (2) | IL199078A (me) |
JO (1) | JO2970B1 (me) |
ME (1) | ME01521B (me) |
MX (1) | MX2009005979A (me) |
MY (1) | MY150411A (me) |
NO (1) | NO342095B1 (me) |
NZ (1) | NZ577128A (me) |
PL (1) | PL2099760T3 (me) |
PT (1) | PT2099760E (me) |
RS (1) | RS52753B (me) |
SG (1) | SG10201405650SA (me) |
SI (1) | SI2099760T1 (me) |
TW (1) | TWI396536B (me) |
UA (1) | UA101306C2 (me) |
WO (1) | WO2008068268A1 (me) |
ZA (1) | ZA200903946B (me) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO2970B1 (en) * | 2006-12-06 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
PL2841425T3 (pl) | 2012-04-27 | 2016-10-31 | Antybakteryjne pochodne chinoliny | |
EA038350B1 (ru) | 2012-04-27 | 2021-08-12 | Янссен Фармацевтика Нв | Антибактериальные хинолиновые производные |
EP4148053A1 (en) | 2016-03-07 | 2023-03-15 | The Global Alliance for TB Drug Development, Inc. | Antibacterial compounds and uses thereof |
US11857352B2 (en) | 2016-09-06 | 2024-01-02 | The Research Foundation For The State University Of New York | Positron imaging tomography imaging agent composition and method for bacterial infection |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5965572A (en) * | 1996-10-28 | 1999-10-12 | The United States Of America As Respresented By The Secretary Of The Army | Methods for treating antibiotic-resistant infections |
US6103905A (en) | 1997-06-19 | 2000-08-15 | Sepracor, Inc. | Quinoline-indole antimicrobial agents, uses and compositions related thereto |
NZ538391A (en) * | 2002-07-25 | 2005-10-28 | Janssen Pharmaceutica Nv | Quinoline derivatives and their use as mycobacterial inhibitors |
US7338949B2 (en) | 2004-01-23 | 2008-03-04 | Janssen Pharmaceutica N.V. | Mycobacterial inhibitors |
DK1711181T3 (da) | 2004-01-23 | 2010-02-01 | Janssen Pharmaceutica Nv | Quinolin-derivater og anvendelse af disse som mycobakterielle inhibitorer |
DE602005006744D1 (de) | 2004-01-29 | 2008-06-26 | Janssen Pharmaceutica Nv | Chinolinderivate zur verwendung als inhibitoren von mycobakterien |
KR101371653B1 (ko) | 2004-05-28 | 2014-03-07 | 얀센 파마슈티카 엔.브이. | 약물 내성 마이코박테리아 질환 치료를 위한 치환된 퀴놀린유도체의 용도 |
RU2418001C2 (ru) | 2004-09-28 | 2011-05-10 | Янссен Фармацевтика Н.В. | Домен связывания бактериальной атр-синтазы |
EE05394B1 (et) | 2004-12-24 | 2011-04-15 | Janssen Pharmaceutica N.V. | Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis |
CA2528849C (en) | 2005-06-08 | 2014-01-14 | Janssen Pharmaceutica N.V. | Quinoline derivatives as antibacterial agents |
WO2007000434A1 (en) | 2005-06-28 | 2007-01-04 | Janssen Pharmaceutica N.V. | Quinoline derivatives as antibacterial agents |
JO2752B1 (en) | 2005-06-28 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
JO2970B1 (en) * | 2006-12-06 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
JO2683B1 (en) * | 2006-12-06 | 2013-03-03 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
-
2007
- 2007-11-29 JO JO2007505A patent/JO2970B1/en active
- 2007-12-04 SG SG10201405650SA patent/SG10201405650SA/en unknown
- 2007-12-04 SI SI200731214T patent/SI2099760T1/sl unknown
- 2007-12-04 KR KR1020097012242A patent/KR101574642B1/ko active Application Filing
- 2007-12-04 KR KR1020157031291A patent/KR101908350B1/ko active IP Right Grant
- 2007-12-04 UA UAA200904217A patent/UA101306C2/ru unknown
- 2007-12-04 ME MEP-2013-43A patent/ME01521B/me unknown
- 2007-12-04 AP AP2009004871A patent/AP2670A/xx active
- 2007-12-04 MX MX2009005979A patent/MX2009005979A/es active IP Right Grant
- 2007-12-04 MY MYPI20092286 patent/MY150411A/en unknown
- 2007-12-04 NZ NZ577128A patent/NZ577128A/en unknown
- 2007-12-04 WO PCT/EP2007/063314 patent/WO2008068268A1/en active Application Filing
- 2007-12-04 EA EA200970536A patent/EA022344B1/ru unknown
- 2007-12-04 CA CA2668517A patent/CA2668517C/en active Active
- 2007-12-04 US US12/516,249 patent/US8293732B2/en active Active
- 2007-12-04 PL PL07847812T patent/PL2099760T3/pl unknown
- 2007-12-04 CN CN200780044895.7A patent/CN101547905B/zh active Active
- 2007-12-04 PT PT78478120T patent/PT2099760E/pt unknown
- 2007-12-04 RS RS20130165A patent/RS52753B/en unknown
- 2007-12-04 BR BRPI0719939A patent/BRPI0719939B8/pt active IP Right Grant
- 2007-12-04 JP JP2009539739A patent/JP5466012B2/ja active Active
- 2007-12-04 ES ES07847812T patent/ES2407824T3/es active Active
- 2007-12-04 DK DK07847812.0T patent/DK2099760T3/da active
- 2007-12-04 EP EP07847812A patent/EP2099760B1/en active Active
- 2007-12-04 KR KR1020167037101A patent/KR20170003741A/ko not_active Application Discontinuation
- 2007-12-05 TW TW096146215A patent/TWI396536B/zh active
- 2007-12-05 CL CL200703515A patent/CL2007003515A1/es unknown
- 2007-12-05 AR ARP070105440A patent/AR064147A1/es unknown
-
2009
- 2009-06-02 IL IL199078A patent/IL199078A/en active IP Right Grant
- 2009-06-05 ZA ZA200903946A patent/ZA200903946B/xx unknown
- 2009-07-06 NO NO20092536A patent/NO342095B1/no unknown
-
2010
- 2010-02-01 HK HK10101095.0A patent/HK1137433A1/xx unknown
-
2013
- 2013-04-26 HR HRP20130372TT patent/HRP20130372T1/hr unknown
- 2013-05-17 CY CY20131100403T patent/CY1114384T1/el unknown
-
2015
- 2015-09-10 IL IL241548A patent/IL241548B/en active IP Right Grant
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