MD20170071A2 - Compoziţii injectabile de paracetamol - Google Patents
Compoziţii injectabile de paracetamolInfo
- Publication number
- MD20170071A2 MD20170071A2 MDA20170071A MD20170071A MD20170071A2 MD 20170071 A2 MD20170071 A2 MD 20170071A2 MD A20170071 A MDA20170071 A MD A20170071A MD 20170071 A MD20170071 A MD 20170071A MD 20170071 A2 MD20170071 A2 MD 20170071A2
- Authority
- MD
- Moldova
- Prior art keywords
- paracetamol
- injectable formulations
- pharmaceutically acceptable
- acceptable salt
- slow
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Invenţia se referă la compoziţii injectabile cu volum redus de paracetamol sau o sare farmaceutic acceptabilă a acestuia şi la o metodă de obţinere a acestora. Compoziţiile asigură o concentraţie mare de paracetamol sau de o sare farmaceutic acceptabilă a acestuia într-un sistem de solvenţi şi pot fi administrate nu numai intramuscular şi prin perfuzie intravenoasă, dar sunt potrivite şi pentru administrare lentă intravenoasă în bolus după diluare cu soluţii apoase până la un volum final de cel mult 20 ml. Aceste compoziţii injectabile rămân stabile şi sunt, de asemenea, potrivite pentru administrare pe cale intravenoasă lentă cu efecte secundare minime, cum sunt flebita, durerea etc.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN4102MU2014 | 2014-12-20 | ||
| PCT/IB2015/058876 WO2016097899A1 (en) | 2014-12-20 | 2015-11-17 | Injectable formulations of paracetamol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MD20170071A2 true MD20170071A2 (ro) | 2017-09-30 |
Family
ID=55022620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20170071A MD20170071A2 (ro) | 2014-12-20 | 2015-11-17 | Compoziţii injectabile de paracetamol |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US20180000940A1 (ro) |
| EP (1) | EP3233055A1 (ro) |
| JP (1) | JP2017538762A (ro) |
| KR (1) | KR20170099911A (ro) |
| CN (1) | CN107205924A (ro) |
| AR (1) | AR103188A1 (ro) |
| AU (1) | AU2015365533A1 (ro) |
| BR (1) | BR112017012975B1 (ro) |
| CA (1) | CA2969303A1 (ro) |
| CL (1) | CL2017001629A1 (ro) |
| CO (1) | CO2017006268A2 (ro) |
| CU (1) | CU20170088A7 (ro) |
| DO (1) | DOP2017000134A (ro) |
| EA (1) | EA201791409A1 (ro) |
| EC (1) | ECSP17038668A (ro) |
| IL (1) | IL252729A0 (ro) |
| JO (1) | JO3689B1 (ro) |
| MA (1) | MA40599A1 (ro) |
| MD (1) | MD20170071A2 (ro) |
| MX (1) | MX2017008264A (ro) |
| PE (1) | PE20171305A1 (ro) |
| PH (1) | PH12017501005A1 (ro) |
| SG (1) | SG11201704435PA (ro) |
| TN (1) | TN2017000232A1 (ro) |
| TW (1) | TWI649097B (ro) |
| UA (1) | UA122136C2 (ro) |
| UY (1) | UY36466A (ro) |
| WO (1) | WO2016097899A1 (ro) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107229455B (zh) | 2016-03-24 | 2019-09-17 | 阿里巴巴集团控股有限公司 | 一种业务处理方法、装置及系统 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2751875B1 (fr) | 1996-08-05 | 1998-12-24 | Scr Newpharm | Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation |
| IT1301976B1 (it) * | 1998-07-31 | 2000-07-20 | Angelini Ricerche Spa | Composizione farmaceutica iniettabile a base di paracetamolo |
| IT1313579B1 (it) | 1999-07-30 | 2002-09-09 | Acraf | Composizione farmaceutica liquida a base di paracetamolo. |
| ITMI20012135A1 (it) | 2001-10-16 | 2003-04-16 | Bioren S A | Soluzioni iniettabili pronte all'uso di paracetamolo |
| MX2007014862A (es) * | 2005-05-27 | 2008-02-21 | Panacea Biotec Ltd | Composiciones inyectables y procedimiento para la preparacion de dichas composiciones. |
| DK1973527T3 (da) * | 2005-12-15 | 2010-02-01 | Acusphere Inc | Fremgangsmåder til fremstilling af partikelbaserede farmaceutiske formulationer til parenteral indgivelse |
| EP2170313A2 (en) | 2007-06-18 | 2010-04-07 | Combino Pharm, S.L. | Aqueous formulations of acetaminophen for injection |
| WO2009098716A2 (en) | 2008-01-17 | 2009-08-13 | Aptuit Laurus Private Limited | Stable pharmaceutical aqueous compositions |
| CN102159184B (zh) * | 2008-10-09 | 2013-09-04 | 方济各安吉利克化学联合股份有限公司 | 含有对乙酰氨基酚的液体药物制剂 |
| BR112012031928B1 (pt) | 2010-06-30 | 2021-08-31 | Troikaa Pharmaceuticals Ltd | Composições farmacêuticas as quais incluem paracetamol e processo para preparação do mesmo |
| TWI577377B (zh) * | 2010-09-16 | 2017-04-11 | Ｖｉｉｖ醫療保健公司 | 醫藥組合物 |
| CN102258485A (zh) * | 2011-01-11 | 2011-11-30 | 北京润德康医药技术有限公司 | 一种含对乙酰氨基酚的注射用制剂及其应用 |
| CN102600068A (zh) * | 2011-01-24 | 2012-07-25 | 联康药业克雷恩特塞提斯制药实验室有限责任公司 | 稳定即用的可注射扑热息痛制剂 |
-
2015
- 2015-11-17 PE PE2017001066A patent/PE20171305A1/es unknown
- 2015-11-17 BR BR112017012975-2A patent/BR112017012975B1/pt active IP Right Grant
- 2015-11-17 MA MA40599A patent/MA40599A1/fr unknown
- 2015-11-17 MX MX2017008264A patent/MX2017008264A/es unknown
- 2015-11-17 TN TN2017000232A patent/TN2017000232A1/en unknown
- 2015-11-17 WO PCT/IB2015/058876 patent/WO2016097899A1/en active Application Filing
- 2015-11-17 MD MDA20170071A patent/MD20170071A2/ro not_active Application Discontinuation
- 2015-11-17 CN CN201580069391.5A patent/CN107205924A/zh active Pending
- 2015-11-17 KR KR1020177017759A patent/KR20170099911A/ko not_active Application Discontinuation
- 2015-11-17 CA CA2969303A patent/CA2969303A1/en not_active Abandoned
- 2015-11-17 JP JP2017533277A patent/JP2017538762A/ja active Pending
- 2015-11-17 EP EP15816228.9A patent/EP3233055A1/en active Pending
- 2015-11-17 CU CUP2017000088A patent/CU20170088A7/es unknown
- 2015-11-17 US US15/537,642 patent/US20180000940A1/en not_active Abandoned
- 2015-11-17 UA UAA201706668A patent/UA122136C2/uk unknown
- 2015-11-17 AU AU2015365533A patent/AU2015365533A1/en not_active Abandoned
- 2015-11-17 EA EA201791409A patent/EA201791409A1/ru unknown
- 2015-11-17 SG SG11201704435PA patent/SG11201704435PA/en unknown
- 2015-11-27 TW TW104139783A patent/TWI649097B/zh not_active IP Right Cessation
- 2015-12-09 JO JOP/2015/0303A patent/JO3689B1/ar active
- 2015-12-21 UY UY0001036466A patent/UY36466A/es unknown
- 2015-12-21 AR ARP150104211A patent/AR103188A1/es unknown
-
2017
- 2017-05-31 PH PH12017501005A patent/PH12017501005A1/en unknown
- 2017-06-06 IL IL252729A patent/IL252729A0/en unknown
- 2017-06-09 DO DO2017000134A patent/DOP2017000134A/es unknown
- 2017-06-20 CL CL2017001629A patent/CL2017001629A1/es unknown
- 2017-06-20 EC ECIEPI201738668A patent/ECSP17038668A/es unknown
- 2017-06-23 CO CONC2017/0006268A patent/CO2017006268A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2969303A1 (en) | 2016-06-23 |
| CU20170088A7 (es) | 2018-03-13 |
| MX2017008264A (es) | 2017-10-02 |
| CN107205924A (zh) | 2017-09-26 |
| EP3233055A1 (en) | 2017-10-25 |
| SG11201704435PA (en) | 2017-06-29 |
| WO2016097899A1 (en) | 2016-06-23 |
| ECSP17038668A (es) | 2017-12-01 |
| KR20170099911A (ko) | 2017-09-01 |
| CL2017001629A1 (es) | 2018-03-16 |
| PH12017501005A1 (en) | 2017-12-11 |
| UY36466A (es) | 2016-07-29 |
| JP2017538762A (ja) | 2017-12-28 |
| JO3689B1 (ar) | 2020-08-27 |
| TW201622703A (zh) | 2016-07-01 |
| TWI649097B (zh) | 2019-02-01 |
| MA40599A1 (fr) | 2017-11-30 |
| BR112017012975A2 (pt) | 2018-02-27 |
| TN2017000232A1 (en) | 2018-10-19 |
| IL252729A0 (en) | 2017-08-31 |
| UA122136C2 (uk) | 2020-09-25 |
| AR103188A1 (es) | 2017-04-19 |
| DOP2017000134A (es) | 2017-09-15 |
| PE20171305A1 (es) | 2017-09-05 |
| US20180000940A1 (en) | 2018-01-04 |
| AU2015365533A1 (en) | 2017-07-06 |
| BR112017012975B1 (pt) | 2023-09-26 |
| EA201791409A1 (ru) | 2017-10-31 |
| CO2017006268A2 (es) | 2017-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA9A | Abandonment or withdrawal of application (patent for invention) |