MC1954A1 - Nouveaux composes,procede pour leur preparation et compositions pharmaceutiques les contenant - Google Patents

Nouveaux composes,procede pour leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
MC1954A1
MC1954A1 MC881989A MC1989A MC1954A1 MC 1954 A1 MC1954 A1 MC 1954A1 MC 881989 A MC881989 A MC 881989A MC 1989 A MC1989 A MC 1989A MC 1954 A1 MC1954 A1 MC 1954A1
Authority
MC
Monaco
Prior art keywords
lower alkyl
aryl
hydrogen
independently
het
Prior art date
Application number
MC881989A
Other languages
English (en)
French (fr)
Inventor
William Guthrie Robert
Wightman Kierstead Richard
Wright Tilley Jefferson
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1954A1 publication Critical patent/MC1954A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56Amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MC881989A 1987-07-10 1988-07-08 Nouveaux composes,procede pour leur preparation et compositions pharmaceutiques les contenant MC1954A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/072,389 US4788206A (en) 1987-07-10 1987-07-10 Pentadieneamides

Publications (1)

Publication Number Publication Date
MC1954A1 true MC1954A1 (fr) 1989-06-30

Family

ID=22107243

Family Applications (1)

Application Number Title Priority Date Filing Date
MC881989A MC1954A1 (fr) 1987-07-10 1988-07-08 Nouveaux composes,procede pour leur preparation et compositions pharmaceutiques les contenant

Country Status (21)

Country Link
US (1) US4788206A (es)
EP (1) EP0299379B1 (es)
JP (1) JPS6431766A (es)
KR (1) KR890001989A (es)
AT (1) ATE88466T1 (es)
AU (1) AU626526B2 (es)
CZ (1) CZ394991A3 (es)
DE (1) DE3880387D1 (es)
DK (1) DK378188A (es)
ES (1) ES2054740T3 (es)
FI (1) FI883290A (es)
HU (1) HU205902B (es)
IL (1) IL87017A0 (es)
MC (1) MC1954A1 (es)
MX (1) MX9203599A (es)
NO (1) NO883084L (es)
NZ (1) NZ225327A (es)
PH (1) PH24605A (es)
PT (1) PT87953B (es)
YU (1) YU46716B (es)
ZA (1) ZA884857B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87019A (en) * 1987-07-10 1993-07-08 Hoffmann La Roche Substituted alkene carboxamides and derivatives, their manufacture and pharmaceutical compositions containing them
US5369106A (en) * 1989-04-28 1994-11-29 Sankyo Company, Limited N-acryloylpiperazine derivatives, their preparation and their use of PAF antagonists
US5192766A (en) * 1989-04-28 1993-03-09 Sankyo Company, Limited N-acryloylpiperazine derivatives, their preparation and their use as PAF antagonists
KR100568997B1 (ko) * 1996-04-23 2006-12-15 타가셉트 인코포레이티드 중추신경계질환의예방및치료를위한약제학적조성물
EP1997806A1 (en) * 1996-04-23 2008-12-03 Targacept, Inc. Pahrmaceutical compositions for prevention and treatment of central nervous system disorders
AU2652397A (en) * 1996-05-13 1997-12-05 Nippon Shinyaku Co. Ltd. Substituted ethylene compounds and drugs
CA2312720A1 (en) * 1997-12-11 1999-06-17 Janssen-Cilag S.A. Retinoic acid mimetic anilides
US6232316B1 (en) 1998-06-16 2001-05-15 Targacept, Inc. Methods for treatment of CNS disorders
DE19828463A1 (de) * 1998-06-26 1999-12-30 Basf Ag 4,4-Diarylbutadiene als wasserlösliche photostabile UV-Filter für kosmetische und pharmazeutische Zubereitungen
AU5326100A (en) * 1999-06-07 2000-12-28 Targacept, Inc. Pharmaceutical compositions and methods for use
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
ES2319886T3 (es) * 2002-02-20 2009-05-14 Abbott Laboratories Compuestos azabiciclicos condensados que inhiben el sutipo 1 del receptor valinoide (vr1).
JP2006519874A (ja) * 2003-03-05 2006-08-31 セルジーン・コーポレーション ジフェニルエチレン化合物およびその使用
US7772271B2 (en) * 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7868037B2 (en) * 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7781478B2 (en) * 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
BRPI0511834A (pt) * 2004-07-14 2008-01-08 Ptc Therapeutics Inc métodos por tratar hepatite c
NZ553329A (en) * 2004-07-22 2010-09-30 Ptc Therapeutics Inc Thienopyridines for treating hepatitis C
CN101489989A (zh) 2006-07-13 2009-07-22 协和发酵麒麟株式会社 戊二烯酰胺衍生物
TW200824687A (en) 2006-08-25 2008-06-16 Abbott Lab Compounds that inhibit TRPV1 and uses thereof
KR101660059B1 (ko) * 2008-08-22 2016-09-26 박스알타 인코퍼레이티드 중합체 벤질 카르보네이트-유도체

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3072649A (en) * 1963-01-08 S-tmalkoxycinnamamide derivatives
US4568687A (en) * 1983-02-28 1986-02-04 American Cyanamid Company N-[2-4-(1H-Imidazol-1-yl)alkyl]-arylamides and pharmaceutical compositions
US4568685A (en) * 1984-02-29 1986-02-04 American Cyanamid Company N-[(1H-1,2,4-Triazol-1-yl)alkyl]-arylamides
US4542145A (en) * 1984-02-29 1985-09-17 American Cyanamid Company Substituted N-[(1H-1,2,4-triazol-1-yl)-alkyl]heteroarylcarboxamides
US4673684A (en) * 1984-04-04 1987-06-16 Terumo Corporation Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient
JPS6144870A (ja) * 1984-08-10 1986-03-04 Terumo Corp 不飽和脂肪酸アミド誘導体およびこれを含有する血小板凝集抑制剤
JPS6144869A (ja) * 1984-08-10 1986-03-04 Terumo Corp イミダゾ−ル誘導体およびこれを含有する血小板凝集抑制剤
JPS6212757A (ja) * 1985-07-10 1987-01-21 Yoshitomi Pharmaceut Ind Ltd 桂皮酸アミド誘導体
US4778796A (en) * 1985-07-19 1988-10-18 Dainippon Pharmaceutical Co., Ltd. ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same
JPH06144869A (ja) * 1992-11-10 1994-05-24 Matsunami Glass Kogyo Kk バイオ担体用多孔質ガラス

Also Published As

Publication number Publication date
US4788206A (en) 1988-11-29
ES2054740T3 (es) 1994-08-16
NO883084L (no) 1989-01-11
PH24605A (en) 1990-08-17
DE3880387D1 (de) 1993-05-27
YU46716B (sh) 1994-04-05
EP0299379B1 (de) 1993-04-21
ZA884857B (en) 1989-04-26
HUT48594A (en) 1989-06-28
DK378188D0 (da) 1988-07-07
AU1885188A (en) 1989-01-12
NO883084D0 (no) 1988-07-08
PT87953B (pt) 1995-03-01
KR890001989A (ko) 1989-04-07
FI883290A0 (fi) 1988-07-08
JPS6431766A (en) 1989-02-02
AU626526B2 (en) 1992-08-06
DK378188A (da) 1989-01-11
IL87017A0 (en) 1988-12-30
ATE88466T1 (de) 1993-05-15
NZ225327A (en) 1991-08-27
MX9203599A (es) 1992-07-01
FI883290A (fi) 1989-01-11
YU132488A (en) 1991-02-28
EP0299379A1 (de) 1989-01-18
CZ394991A3 (en) 1993-01-13
PT87953A (pt) 1989-06-30
HU205902B (en) 1992-07-28

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