MC1286A1 - Preparation de composes heterocycliques utilisables en pharmacie et de medicaments contenant ces composes - Google Patents

Preparation de composes heterocycliques utilisables en pharmacie et de medicaments contenant ces composes

Info

Publication number
MC1286A1
MC1286A1 MC791413A MC1413A MC1286A1 MC 1286 A1 MC1286 A1 MC 1286A1 MC 791413 A MC791413 A MC 791413A MC 1413 A MC1413 A MC 1413A MC 1286 A1 MC1286 A1 MC 1286A1
Authority
MC
Monaco
Prior art keywords
carbazole
cis
compound
formula
process according
Prior art date
Application number
MC791413A
Other languages
English (en)
French (fr)
Inventor
M Harfenist
C Joyner
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MC1286A1 publication Critical patent/MC1286A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MC791413A 1978-11-01 1979-10-31 Preparation de composes heterocycliques utilisables en pharmacie et de medicaments contenant ces composes MC1286A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7842845 1978-11-01
US1691479A 1979-03-02 1979-03-02

Publications (1)

Publication Number Publication Date
MC1286A1 true MC1286A1 (fr) 1980-07-22

Family

ID=26269424

Family Applications (1)

Application Number Title Priority Date Filing Date
MC791413A MC1286A1 (fr) 1978-11-01 1979-10-31 Preparation de composes heterocycliques utilisables en pharmacie et de medicaments contenant ces composes

Country Status (15)

Country Link
US (1) US4379160A (cs)
EP (2) EP0051321B1 (cs)
KR (2) KR860001253B1 (cs)
AU (1) AU537630B2 (cs)
BG (1) BG33279A3 (cs)
CA (1) CA1141384A (cs)
DD (1) DD147110A5 (cs)
DK (1) DK460879A (cs)
GR (1) GR69858B (cs)
IE (1) IE48979B1 (cs)
IL (1) IL58592A (cs)
MC (1) MC1286A1 (cs)
MY (1) MY8500221A (cs)
NZ (1) NZ191987A (cs)
PH (1) PH14576A (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469868A (en) * 1982-05-24 1984-09-04 Warner-Lambert Company Alkylimidazo[1,2-c]pyrazolo[3,4-e]pyrimidines
GR871809B (en) * 1986-11-28 1988-03-07 Glaxo Group Ltd Process for the preparation of tricyclic ketones
US5116995A (en) * 1990-05-25 1992-05-26 Taisho Pharmaceutical Co., Ltd. Carbazole compounds
CA2187542C (en) * 1994-04-18 2000-02-01 Nobuyuki Takahashi Adamantane derivative, process for producing the same, and use thereof
US6025355A (en) * 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
IL130055A0 (en) * 1996-11-22 2000-02-29 Lilly Co Eli Drug resistance and multidrug resistance modulators
EP1094063A1 (en) 1999-10-18 2001-04-25 Applied Research Systems ARS Holding N.V. 9-(Piperazinylalkyl)carbazoles as Bax-modulators
GB0619398D0 (en) * 2006-10-02 2006-11-08 Univ Dundee Manufacture of rimcazole
GB0907973D0 (en) 2009-05-08 2009-06-24 Modern Biosciences Plc Combination therapy
EP4153209A1 (en) 2020-05-20 2023-03-29 The Board of Trustees of the University of Illinois Method for treating lysosomal storage diseases with histatin peptides
WO2025031979A1 (en) 2023-08-04 2025-02-13 Kyrexa Ltd Use of rimcazole to treat cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE539438A (cs) * 1954-07-01
DE2339396C2 (de) * 1973-08-03 1984-06-28 Boehringer Mannheim Gmbh, 6800 Mannheim N-substituierte 1-Amino-3-phenoxypropan-2-ole, deren Salze, Verfahren zu deren Herstellung sowie Arzneimittel, die diese Verbindungen enthalten

Also Published As

Publication number Publication date
AU5237879A (en) 1980-06-12
KR860001252B1 (ko) 1986-09-01
IL58592A (en) 1982-12-31
US4379160A (en) 1983-04-05
BG33279A3 (en) 1983-01-14
AU537630B2 (en) 1984-07-05
GR69858B (cs) 1982-07-19
CA1141384A (en) 1983-02-15
KR840004688A (ko) 1984-10-22
KR840004689A (ko) 1984-10-22
EP0051321A1 (en) 1982-05-12
DD147110A5 (de) 1981-03-18
IL58592A0 (en) 1980-01-31
EP0051321B1 (en) 1986-03-26
NZ191987A (en) 1984-10-19
IE48979B1 (en) 1985-06-26
EP0012208A2 (en) 1980-06-25
IE792083L (en) 1980-05-01
PH14576A (en) 1981-09-24
EP0012208A3 (en) 1980-07-23
KR860001253B1 (ko) 1986-09-01
DK460879A (da) 1980-05-02
MY8500221A (en) 1985-12-31
EP0012208B1 (en) 1983-01-26

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