MA54296A - Procédés de traitement du métabolisme lipidique dérégulé - Google Patents
Procédés de traitement du métabolisme lipidique déréguléInfo
- Publication number
- MA54296A MA54296A MA054296A MA54296A MA54296A MA 54296 A MA54296 A MA 54296A MA 054296 A MA054296 A MA 054296A MA 54296 A MA54296 A MA 54296A MA 54296 A MA54296 A MA 54296A
- Authority
- MA
- Morocco
- Prior art keywords
- treating
- methods
- lipid metabolism
- disregulated
- disregulated lipid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862771456P | 2018-11-26 | 2018-11-26 | |
US201962817955P | 2019-03-13 | 2019-03-13 | |
US201962890506P | 2019-08-22 | 2019-08-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA54296A true MA54296A (fr) | 2021-10-06 |
Family
ID=68988303
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA054296A MA54296A (fr) | 2018-11-26 | 2019-11-26 | Procédés de traitement du métabolisme lipidique dérégulé |
Country Status (7)
Country | Link |
---|---|
US (1) | US20230132366A9 (fr) |
EP (1) | EP3887401A2 (fr) |
JP (1) | JP2022513114A (fr) |
CN (1) | CN113302206A (fr) |
CA (1) | CA3120970A1 (fr) |
MA (1) | MA54296A (fr) |
WO (1) | WO2020112889A2 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2020508049A (ja) | 2017-02-17 | 2020-03-19 | デナリ セラピューティクス インコーポレイテッドDenali Therapeutics Inc. | 操作されたトランスフェリン受容体結合ポリペプチド |
JOP20190248A1 (ar) | 2017-04-21 | 2019-10-20 | Amgen Inc | بروتينات ربط مولد ضد trem2 واستخداماته |
WO2021146256A1 (fr) | 2020-01-13 | 2021-07-22 | Denali Therapeutics Inc. | Anticorps anti-trem2 et leurs procédés d'utilisation |
BR112022013756A2 (pt) | 2020-01-13 | 2022-10-11 | Denali Therapeutics Inc | Anticorpos anti-trem2 e métodos de uso dos mesmos |
WO2021250428A1 (fr) * | 2020-06-11 | 2021-12-16 | Quell Therapeutics Limited | Récepteur chimérique de trem2 |
TW202218683A (zh) * | 2020-08-05 | 2022-05-16 | 美商維佳神經科學有限公司 | 使用trem2促效劑治療與群落刺激因子1受體功能障礙相關之疾病 |
CN115015412B (zh) * | 2022-05-26 | 2024-07-05 | 江苏独步生物科技有限公司 | 一种与中枢神经损伤修复相关的分子靶标及其应用 |
CN117771226B (zh) * | 2023-12-28 | 2024-08-20 | 山东博森医学工程技术有限公司 | 一种加快骨关节炎损伤修复的促进剂 |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR14523E (fr) | 1911-02-06 | 1911-12-30 | Daniel German Caswell | Perfectionnements dans les vélocipèdes |
US4326055A (en) | 1977-12-22 | 1982-04-20 | Hoffmann-La Roche Inc. | Stilbene derivatives |
DE3202100A1 (de) | 1982-01-23 | 1983-08-04 | Basf Ag, 6700 Ludwigshafen | Substituierte benzoesaeure-4-hydroxyanilide, ihre herstellung und diese enthaltende pharmazeutische zubereitungen |
US4559157A (en) | 1983-04-21 | 1985-12-17 | Creative Products Resource Associates, Ltd. | Cosmetic applicator useful for skin moisturizing |
LU84979A1 (fr) | 1983-08-30 | 1985-04-24 | Oreal | Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux |
US4820508A (en) | 1987-06-23 | 1989-04-11 | Neutrogena Corporation | Skin protective composition |
US4992478A (en) | 1988-04-04 | 1991-02-12 | Warner-Lambert Company | Antiinflammatory skin moisturizing composition and method of preparing same |
US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
ATE163544T1 (de) | 1991-12-18 | 1998-03-15 | Salk Inst For Biological Studi | Mitteln zur modulierung von verfahren durch retinoid rezeptoren und dafür nützliche verbindungen |
US5780676A (en) | 1992-04-22 | 1998-07-14 | Ligand Pharmaceuticals Incorporated | Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors |
AU675430B2 (en) | 1992-04-22 | 1997-02-06 | Ligand Pharmaceuticals Incorporated | Compounds having selectivity for retinoid X receptors |
US5466861A (en) | 1992-11-25 | 1995-11-14 | Sri International | Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors |
WO1995004036A1 (fr) | 1993-01-11 | 1995-02-09 | Ligand Pharmaceuticals Inc. | Composes a activite selective pour les recepteurs du retinoide x, et systeme de modulation des processus utilisant des recepteurs du retinoide x comme mediateurs |
PT678086E (pt) | 1993-01-11 | 2000-05-31 | Ligand Pharm Inc | Compostos com selectividade para receptores de retinoides x |
US5399586A (en) | 1993-03-11 | 1995-03-21 | Allergan, Inc. | Treatment of mammals afflicted with tumors with compounds having RXR retinoid receptor agonist activity |
WO1994023068A1 (fr) | 1993-04-07 | 1994-10-13 | Ligand Pharmaceuticals, Incorporated | Procede de triage concernant des agonistes de recepteurs |
ATE181052T1 (de) | 1994-08-10 | 1999-06-15 | Hoffmann La Roche | Retinoesäure x-rezeptor liganden |
US6083977A (en) | 1994-12-30 | 2000-07-04 | Ligand Pharmaceuticals Incorporated | Trienoic retinoid compounds and methods |
DE69516903T2 (de) | 1994-12-30 | 2000-10-26 | Ligand Pharmaceuticals, Inc. | Retinoid trienverbindungen und verfahren |
JPH09330101A (ja) | 1996-06-13 | 1997-12-22 | Kokusai Chodendo Sangyo Gijutsu Kenkyu Center | 制御装置及び方法 |
IT1286031B1 (it) | 1996-10-24 | 1998-07-07 | Enichem Spa | Procedimento per la produzione di polimeri vinilaromatici ad elevato grado di sindiotassia |
US6969711B2 (en) | 1997-05-26 | 2005-11-29 | Kowa Company, Ltd. | Cyclic diamine compounds and medicine containing the same |
US6316503B1 (en) | 1999-03-15 | 2001-11-13 | Tularik Inc. | LXR modulators |
US20030086923A1 (en) | 1999-12-13 | 2003-05-08 | Sparrow Carl P. | Method for the prevention and/or treatment of atherosclerosis |
CA2392568A1 (fr) | 1999-12-13 | 2001-06-14 | Merck & Co., Inc. | Procede de prevention et/ou de traitement de l'atherosclerose |
US7482366B2 (en) | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
EP1463726A2 (fr) | 2001-12-21 | 2004-10-06 | Pharmacia Corporation | Modulateurs du recepteur x du foie de thioether aromatique |
WO2003059884A1 (fr) | 2001-12-21 | 2003-07-24 | X-Ceptor Therapeutics, Inc. | Modulateurs de lxr |
EP1480689A1 (fr) | 2002-02-28 | 2004-12-01 | Eli Lilly And Company | Procede servant a traiter l'atherosclerose et l'hypercholesterolemie |
US6900244B2 (en) | 2002-05-24 | 2005-05-31 | Pharmacia Corporation | Anilino liver X-receptor modulators |
BR0311282A (pt) | 2002-05-24 | 2005-04-19 | Pharmacia Corp | Moduladores sulfona de receptor-x do fìgado |
BR0314390A (pt) | 2002-09-17 | 2005-07-19 | Pharmacia Corp | Moduladores aromáticos dos receptores hepáticos x |
US20050036992A1 (en) | 2002-12-23 | 2005-02-17 | Irm Llc | Novel use of liver X receptor agonists |
US20050009837A1 (en) | 2003-05-20 | 2005-01-13 | City Of Hope | Modulators of lipid metabolism and methods of use |
JP2005128010A (ja) * | 2003-10-03 | 2005-05-19 | Takeda Chem Ind Ltd | インスリン抵抗性改善剤のスクリーニング方法 |
BRPI0417543A (pt) | 2003-12-12 | 2007-03-27 | Wyeth Corp | quinolinas úteis no tratamento de doença cardiovascular |
CN101213194A (zh) | 2004-08-03 | 2008-07-02 | 惠氏公司 | 可用于治疗心血管疾病的吲唑化合物 |
AU2007297721A1 (en) | 2006-09-19 | 2008-03-27 | Wyeth | Use of LXR agonists for the treatment of osteoarthritis |
US9149492B2 (en) | 2008-10-08 | 2015-10-06 | Trustees Of Dartmouth College | Method for selectively inhibiting ACAT1 in the treatment of alzheimer's disease |
AU2010209273A1 (en) * | 2009-01-28 | 2011-09-01 | The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center | Eotaxin-2 (CCL24) inhibitors in inflammatory, autoimmune, and cardiovascular disorders |
JP5719340B2 (ja) | 2009-03-20 | 2015-05-20 | レティーナ インプラント アーゲー | 能動型網膜インプラント |
WO2013056232A2 (fr) | 2011-10-13 | 2013-04-18 | Case Western Reserve University | Composés agonistes de rxr et procédés associés |
AU2012352149B2 (en) | 2011-12-13 | 2017-06-01 | Io Therapeutics, Inc. | Autoimmune disorder treatment using RXR agonists |
WO2015038585A1 (fr) | 2013-09-11 | 2015-03-19 | Trustees Of Dartmouth College | Méthode permettant d'inhiber de manière sélective acat1 dans le traitement de la maladie d'alzheimer |
WO2015061686A2 (fr) | 2013-10-25 | 2015-04-30 | St. Jude Children's Research Hospital, Inc. | Agonistes du récepteur des rétinoïdes x type gamma et antagonistes du récepteur des rétinoïdes x type alpha utilisés pour le traitement du cancer |
WO2015184105A1 (fr) | 2014-05-29 | 2015-12-03 | Trustees Of Dartmouth College | Procédé permettant d'inhiber de manière sélective l'acat1 dans le traitement de maladies neurodégénératives |
EP4066859A1 (fr) * | 2014-08-08 | 2022-10-05 | Alector LLC | Anticorps anti-trem2 et leurs procédés d'utilisation |
CA2990578C (fr) | 2015-06-30 | 2023-09-26 | National University Corporation Okayama University | Medicament pour la prevention ou le traitement d'une maladie inflammatoire de l'intestin |
WO2017058866A1 (fr) | 2015-09-28 | 2017-04-06 | Precision Immune, Inc. | Anticorps anti-trem2 et leurs utilisations |
JP2018537956A (ja) * | 2015-10-06 | 2018-12-27 | アレクトル エルエルシー | 抗trem2抗体及びその使用方法 |
US20180318241A1 (en) | 2015-10-31 | 2018-11-08 | Io Therapeutics, Inc. | Treatment of nervous system disorders using thyroid hormone neutral doses of rxr agonists |
WO2018134815A2 (fr) * | 2017-01-17 | 2018-07-26 | Yeda Research And Development Co. Ltd. | Procédés de traitement de maladies neurodégénératives par induction de cellules de microglie associées à une maladie (dam) |
JOP20190248A1 (ar) * | 2017-04-21 | 2019-10-20 | Amgen Inc | بروتينات ربط مولد ضد trem2 واستخداماته |
TW202342547A (zh) | 2017-08-03 | 2023-11-01 | 美商阿列克特有限責任公司 | 抗trem2抗體及其使用方法 |
CA3083660A1 (fr) | 2017-12-12 | 2019-06-20 | Pionyr Immunotherapeutics, Inc. | Anticorps anti-trem2 et methodes associees |
-
2019
- 2019-11-26 CN CN201980089105.XA patent/CN113302206A/zh active Pending
- 2019-11-26 US US17/296,506 patent/US20230132366A9/en active Pending
- 2019-11-26 MA MA054296A patent/MA54296A/fr unknown
- 2019-11-26 CA CA3120970A patent/CA3120970A1/fr active Pending
- 2019-11-26 JP JP2021528981A patent/JP2022513114A/ja active Pending
- 2019-11-26 EP EP19824429.5A patent/EP3887401A2/fr active Pending
- 2019-11-26 WO PCT/US2019/063427 patent/WO2020112889A2/fr unknown
Also Published As
Publication number | Publication date |
---|---|
EP3887401A2 (fr) | 2021-10-06 |
WO2020112889A9 (fr) | 2021-06-10 |
JP2022513114A (ja) | 2022-02-07 |
CN113302206A (zh) | 2021-08-24 |
US20230132366A9 (en) | 2023-04-27 |
US20220025039A1 (en) | 2022-01-27 |
WO2020112889A3 (fr) | 2020-07-30 |
CA3120970A1 (fr) | 2020-06-04 |
WO2020112889A2 (fr) | 2020-06-04 |
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