MA51998A - Nouveaux polymorphes de sel de calcium en tant qu'agents anti-inflammatoires, immunomodulateurs et anti-prolifératifs - Google Patents
Nouveaux polymorphes de sel de calcium en tant qu'agents anti-inflammatoires, immunomodulateurs et anti-prolifératifsInfo
- Publication number
- MA51998A MA51998A MA051998A MA51998A MA51998A MA 51998 A MA51998 A MA 51998A MA 051998 A MA051998 A MA 051998A MA 51998 A MA51998 A MA 51998A MA 51998 A MA51998 A MA 51998A
- Authority
- MA
- Morocco
- Prior art keywords
- immunomodulator
- inflammatory
- calcium salt
- proliferative agents
- new calcium
- Prior art date
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 230000001028 anti-proliverative effect Effects 0.000 title 1
- 159000000007 calcium salts Chemical class 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 239000002955 immunomodulating agent Substances 0.000 title 1
- 229940121354 immunomodulator Drugs 0.000 title 1
- 230000002584 immunomodulator Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18162244 | 2018-03-16 | ||
| PCT/EP2019/056560 WO2019175396A1 (fr) | 2018-03-16 | 2019-03-15 | Nouveaux polymorphes de sel de calcium en tant qu'agents anti-inflammatoires, immunomodulateurs et anti-prolifératifs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA51998A true MA51998A (fr) | 2021-01-20 |
| MA51998B1 MA51998B1 (fr) | 2024-05-31 |
Family
ID=61691328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA51998A MA51998B1 (fr) | 2018-03-16 | 2019-03-15 | Nouveaux polymorphes de sel de calcium en tant qu'agents anti-inflammatoires, immunomodulateurs et anti-prolifératifs |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US12037305B2 (fr) |
| EP (2) | EP4438591A1 (fr) |
| JP (2) | JP7358373B2 (fr) |
| KR (1) | KR20200131249A (fr) |
| CN (1) | CN111836795B (fr) |
| AU (1) | AU2019233698B2 (fr) |
| BR (1) | BR112020017443A2 (fr) |
| CA (1) | CA3093984A1 (fr) |
| DK (1) | DK3765439T3 (fr) |
| ES (1) | ES2980148T3 (fr) |
| FI (1) | FI3765439T3 (fr) |
| HR (1) | HRP20240695T1 (fr) |
| IL (2) | IL307422A (fr) |
| LT (1) | LT3765439T (fr) |
| MA (1) | MA51998B1 (fr) |
| MD (1) | MD3765439T2 (fr) |
| MX (1) | MX2020009612A (fr) |
| PH (1) | PH12020551488A1 (fr) |
| PL (1) | PL3765439T3 (fr) |
| PT (1) | PT3765439T (fr) |
| RS (1) | RS65563B1 (fr) |
| SG (1) | SG11202008032YA (fr) |
| SI (1) | SI3765439T1 (fr) |
| UA (1) | UA128135C2 (fr) |
| WO (1) | WO2019175396A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7504088B2 (ja) * | 2018-10-16 | 2024-06-21 | ジョージア ステイト ユニバーシティー リサーチ ファウンデーション インコーポレイテッド | 医学的障害の治療のための一酸化炭素プロドラッグ |
| AU2021260040A1 (en) | 2020-04-21 | 2022-11-17 | Immunic Ag | Vidofludimus for use in the treatment or prevention of viral diseases |
| WO2022200615A1 (fr) | 2021-03-26 | 2022-09-29 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Combinaison d'inhibiteur de la biosynthèse de la pyrimidine destinée à être utilisée dans le traitement d'infections virales |
| KR20240007144A (ko) | 2021-04-09 | 2024-01-16 | 이뮤닉 아게 | 중수소화 dhodh 억제제 |
| US11877994B2 (en) * | 2021-08-02 | 2024-01-23 | Immunic Ag | Treatment of multiple sclerosis comprising DHODH inhibitors |
| IL313501A (en) | 2021-12-23 | 2024-08-01 | Immunic Ag | DHODH INHIBITORS CONTAINING CARBOXYLIC ACID BIOISOSTERE |
| WO2023232884A1 (fr) | 2022-06-01 | 2023-12-07 | Immunic Ag | Traitement de la colite ulcéreuse comprenant du vidofludimus ou un sel pharmaceutiquement acceptable de celui-ci |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50121428A (fr) | 1974-03-12 | 1975-09-23 | ||
| NL186239B (nl) | 1975-06-05 | Hoechst Ag | Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze. | |
| IL56012A (en) | 1977-11-29 | 1983-07-31 | Takeda Chemical Industries Ltd | N-(2-fluoro-4-bromo(or chloro)phenyl)-3,4,5,6-tetrahydrophthalamic acid derivatives,their preparation,and herbicidal compositions comprising them |
| JPS54154737A (en) | 1978-05-25 | 1979-12-06 | Mitsubishi Chem Ind Ltd | Cyclohexenedicarboxylic acid diamide and herbicide |
| JPS55157547A (en) | 1979-05-28 | 1980-12-08 | Takeda Chem Ind Ltd | Tetrahydrophthalamide derivative, its preparation and herbicide |
| AU1526483A (en) | 1982-06-14 | 1983-12-22 | Nippon Kayaku Kabushiki Kaisha | N-substituted-3,4,5,6-tetrahydrophthalamic acids |
| JPS59118750A (ja) | 1982-12-27 | 1984-07-09 | Eisai Co Ltd | カルボン酸アミド化合物およびその誘導体 |
| DE3534440A1 (de) | 1985-09-27 | 1987-04-02 | Hoechst Ag | Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes |
| GB9320299D0 (en) | 1993-10-01 | 1993-11-17 | Roussel Lab Ltd | Isoxazole derivatives |
| DE19547648A1 (de) | 1995-12-20 | 1997-06-26 | Hoechst Ag | Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate |
| DE19610955A1 (de) | 1996-03-20 | 1997-09-25 | Hoechst Ag | Kombinationspräparat, enthaltend 5-Methylisoxazol-4-carbonsäure-(4-trifluormethyl)- anilid und N-(4-Trifluormethylphenyl)-2-cyan-3- hydroxycrotonsäureamid |
| WO1999038846A1 (fr) | 1998-01-30 | 1999-08-05 | Procept, Inc. | Agents immunosuppresseurs |
| GB9804343D0 (en) | 1998-02-27 | 1998-04-22 | Univ Cardiff | Chemical compounds |
| WO2003006424A1 (fr) | 2001-07-10 | 2003-01-23 | 4Sc Ag | Nouveaux composes utilises comme agents anti-inflammatoires, immunomodulateurs et anti-proliferatoires |
| ATE450498T1 (de) | 2002-12-23 | 2009-12-15 | 4Sc Ag | Cycloalken-dicarbonsäure-verbindungen als entzündungshemmende, immunmodulatorische und antiproliferative mittel |
| UA108760C2 (uk) | 2010-07-01 | 2015-06-10 | Кальцієві солі сполуки як протизапальні, імуномодулюючі та антипроліферативні засоби | |
| SG11201608835VA (en) * | 2014-05-08 | 2016-11-29 | Panoptes Pharma Ges M B H | Compounds for treating ophthalmic diseases and disorders |
| CN108699023A (zh) * | 2015-12-30 | 2018-10-23 | 安吉奥斯医药品有限公司 | 掺入突变型异柠檬酸脱氢酶的肿瘤的治疗 |
-
2019
- 2019-03-15 FI FIEP19711350.9T patent/FI3765439T3/fi active
- 2019-03-15 PT PT197113509T patent/PT3765439T/pt unknown
- 2019-03-15 SI SI201930751T patent/SI3765439T1/sl unknown
- 2019-03-15 IL IL307422A patent/IL307422A/en unknown
- 2019-03-15 LT LTEPPCT/EP2019/056560T patent/LT3765439T/lt unknown
- 2019-03-15 JP JP2020549636A patent/JP7358373B2/ja active Active
- 2019-03-15 KR KR1020207026564A patent/KR20200131249A/ko not_active Application Discontinuation
- 2019-03-15 UA UAA202006622A patent/UA128135C2/uk unknown
- 2019-03-15 DK DK19711350.9T patent/DK3765439T3/da active
- 2019-03-15 MA MA51998A patent/MA51998B1/fr unknown
- 2019-03-15 ES ES19711350T patent/ES2980148T3/es active Active
- 2019-03-15 EP EP24172742.9A patent/EP4438591A1/fr active Pending
- 2019-03-15 IL IL277326A patent/IL277326B2/en unknown
- 2019-03-15 BR BR112020017443-2A patent/BR112020017443A2/pt unknown
- 2019-03-15 WO PCT/EP2019/056560 patent/WO2019175396A1/fr active Application Filing
- 2019-03-15 MD MDE20210073T patent/MD3765439T2/ro unknown
- 2019-03-15 HR HRP20240695TT patent/HRP20240695T1/hr unknown
- 2019-03-15 MX MX2020009612A patent/MX2020009612A/es unknown
- 2019-03-15 RS RS20240575A patent/RS65563B1/sr unknown
- 2019-03-15 CN CN201980018653.3A patent/CN111836795B/zh active Active
- 2019-03-15 EP EP19711350.9A patent/EP3765439B1/fr active Active
- 2019-03-15 AU AU2019233698A patent/AU2019233698B2/en active Active
- 2019-03-15 CA CA3093984A patent/CA3093984A1/fr active Pending
- 2019-03-15 PL PL19711350.9T patent/PL3765439T3/pl unknown
- 2019-03-15 US US16/981,122 patent/US12037305B2/en active Active
- 2019-03-15 SG SG11202008032YA patent/SG11202008032YA/en unknown
-
2020
- 2020-09-16 PH PH12020551488A patent/PH12020551488A1/en unknown
-
2023
- 2023-09-25 JP JP2023159416A patent/JP2024001061A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA51998A (fr) | Nouveaux polymorphes de sel de calcium en tant qu'agents anti-inflammatoires, immunomodulateurs et anti-prolifératifs | |
| MA52486A (fr) | Pyridazinones utilisés en tant qu'inhibiteurs de parp7 | |
| MA54547A (fr) | Amides d'hétéroaryle utiles en tant qu'inhibiteurs de kif18a | |
| MA54546A (fr) | Amides d'hétéroaryle utiles en tant qu'inhibiteurs de kif18a | |
| MA47123A (fr) | Dérivés de benzooxazole en tant qu'mmunomodulateurs | |
| MA49013A (fr) | Nouveaux dérivés hétérocycliques utiles en tant qu'inhibiteurs de shp2 | |
| MA45036A (fr) | Polynucléotides codant pour la citrine pour le traitement de la citrullinémie de type 2 | |
| MA54157A (fr) | Dérivés de spiro-sulfonamide en tant qu'inhibiteurs de la protéine de la leucémie myéloïde -1 (mcl-1) | |
| MA51232A (fr) | Indane-amines utiles en tant qu'antagonistes de pd-l1 | |
| MA42032A (fr) | Acides 3-aryl-4-amido-bicyclo [4,5,0]hydroxamiques en tant qu'inhibiteurs de hdac | |
| MA46180A (fr) | Analogues de l'amyline | |
| MA53229A (fr) | Amides de diméthyl amino azétidine utilisés en tant qu'inhibiteurs de jak | |
| FR3056393B1 (fr) | Orthese d'extension de machoires | |
| MA47736A (fr) | Pyrimidopyrimidinones utiles en tant qu'inhibiteurs de la kinase wee-1 | |
| MA54939A (fr) | Hydroxypyridoxazépines utilisées en tant qu'activateurs de nrf2 | |
| MA54521A (fr) | Dérivés d'oxopyridine substitués | |
| MA53643A (fr) | Dioxocyclobuténylamino-3-hydroxy-picolinamides n-substitués utiles en tant qu'inhibiteurs de ccr6 | |
| MA53164A (fr) | Dérivés de tyrosine amide utilisés en tant qu'inhibiteurs de la rho-kinase | |
| MA50439A (fr) | Nouveaux dérivés de pyrazolo-pyrrolo-pyrimidine-dione utilisés en tant qu'inhibiteurs de p2x3 | |
| MA50074A (fr) | Dérivés d'analogues de tyrosine en tant qu'inhibiteurs de rho-kinase | |
| MA51202A (fr) | Nouveaux dérivés de pipéridinyle utilisés en tant qu'inhibiteurs de la protéase 7 spécifique à l'ubiquitine | |
| MD3288949T2 (ro) | Derivați de aminohidrothiazină fuzionați cu tetrahidrofuran utili în tratamentul bolii Alzheimer | |
| FR3049599B1 (fr) | Procede de preparation de l'hexafluorobutadiene. | |
| MA45686A (fr) | Formes salines de 4-cyano-n-(2-(4,4-diméthylcyclohex-1-en-1-yl)-6-(2,2,6,6-tétraméthyltétrahydro-2h-pyran-4-yl)pyridin-3-yl)-1h-imidazole-2-carboxamide | |
| MA43764A (fr) | Inhibiteur monovalent de l'interaction hutnfr1 |