DK3765439T3 - Nye calciumsaltpolymorfer som anti-inflammatoriske, immunomodulatoriske og anti-proliferative midler - Google Patents
Nye calciumsaltpolymorfer som anti-inflammatoriske, immunomodulatoriske og anti-proliferative midler Download PDFInfo
- Publication number
- DK3765439T3 DK3765439T3 DK19711350.9T DK19711350T DK3765439T3 DK 3765439 T3 DK3765439 T3 DK 3765439T3 DK 19711350 T DK19711350 T DK 19711350T DK 3765439 T3 DK3765439 T3 DK 3765439T3
- Authority
- DK
- Denmark
- Prior art keywords
- immunomodulatory
- inflammatory
- calcium salt
- proliferative agents
- new calcium
- Prior art date
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 230000001028 anti-proliverative effect Effects 0.000 title 1
- 159000000007 calcium salts Chemical class 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 230000002519 immonomodulatory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18162244 | 2018-03-16 | ||
| PCT/EP2019/056560 WO2019175396A1 (en) | 2018-03-16 | 2019-03-15 | Novel calcium salt polymorphs as anti-inflammatory, immunomodulatory and anti-proliferatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3765439T3 true DK3765439T3 (da) | 2024-05-27 |
Family
ID=61691328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19711350.9T DK3765439T3 (da) | 2018-03-16 | 2019-03-15 | Nye calciumsaltpolymorfer som anti-inflammatoriske, immunomodulatoriske og anti-proliferative midler |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20210017125A1 (da) |
| EP (1) | EP3765439B1 (da) |
| JP (2) | JP7358373B2 (da) |
| KR (1) | KR20200131249A (da) |
| CN (1) | CN111836795B (da) |
| AU (1) | AU2019233698B2 (da) |
| BR (1) | BR112020017443A2 (da) |
| CA (1) | CA3093984A1 (da) |
| DK (1) | DK3765439T3 (da) |
| FI (1) | FI3765439T3 (da) |
| IL (2) | IL277326B2 (da) |
| MA (1) | MA51998A (da) |
| MX (1) | MX2020009612A (da) |
| PH (1) | PH12020551488A1 (da) |
| SG (1) | SG11202008032YA (da) |
| UA (1) | UA128135C2 (da) |
| WO (1) | WO2019175396A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA53193A (fr) | 2020-04-21 | 2021-10-27 | Immunic Ag | Vidofludimus à utiliser dans le traitement ou la prévention de maladies virales |
| EP4313150A1 (en) | 2021-03-26 | 2024-02-07 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Pyrimidine biosynthesis inhibitor combination for use in treating viral infections |
| BR112023020806A2 (pt) | 2021-04-09 | 2023-12-12 | Immunic Ag | Inibidores de dhodh deuterados |
| US11877994B2 (en) * | 2021-08-02 | 2024-01-23 | Immunic Ag | Treatment of multiple sclerosis comprising DHODH inhibitors |
| WO2023118576A1 (en) | 2021-12-23 | 2023-06-29 | Immunic Ag | Dhodh inhibitors containing a carboxylic acid bioisostere |
| WO2023232884A1 (en) | 2022-06-01 | 2023-12-07 | Immunic Ag | Treatment of ulcerative colitis comprising vidofludimus or a pharmaceutically acceptable salt thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50121428A (da) | 1974-03-12 | 1975-09-23 | ||
| NL186239B (nl) | 1975-06-05 | Hoechst Ag | Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze. | |
| IL56012A (en) | 1977-11-29 | 1983-07-31 | Takeda Chemical Industries Ltd | N-(2-fluoro-4-bromo(or chloro)phenyl)-3,4,5,6-tetrahydrophthalamic acid derivatives,their preparation,and herbicidal compositions comprising them |
| JPS54154737A (en) | 1978-05-25 | 1979-12-06 | Mitsubishi Chem Ind Ltd | Cyclohexenedicarboxylic acid diamide and herbicide |
| JPS55157547A (en) | 1979-05-28 | 1980-12-08 | Takeda Chem Ind Ltd | Tetrahydrophthalamide derivative, its preparation and herbicide |
| AU1526483A (en) | 1982-06-14 | 1983-12-22 | Nippon Kayaku Kabushiki Kaisha | N-substituted-3,4,5,6-tetrahydrophthalamic acids |
| JPS59118750A (ja) | 1982-12-27 | 1984-07-09 | Eisai Co Ltd | カルボン酸アミド化合物およびその誘導体 |
| DE3534440A1 (de) | 1985-09-27 | 1987-04-02 | Hoechst Ag | Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes |
| GB9320299D0 (en) | 1993-10-01 | 1993-11-17 | Roussel Lab Ltd | Isoxazole derivatives |
| DE19547648A1 (de) | 1995-12-20 | 1997-06-26 | Hoechst Ag | Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate |
| DE19610955A1 (de) | 1996-03-20 | 1997-09-25 | Hoechst Ag | Kombinationspräparat, enthaltend 5-Methylisoxazol-4-carbonsäure-(4-trifluormethyl)- anilid und N-(4-Trifluormethylphenyl)-2-cyan-3- hydroxycrotonsäureamid |
| AU2108099A (en) | 1998-01-30 | 1999-08-16 | Procept, Inc. | Immunosuppressive agents |
| GB9804343D0 (en) | 1998-02-27 | 1998-04-22 | Univ Cardiff | Chemical compounds |
| WO2003006424A1 (en) | 2001-07-10 | 2003-01-23 | 4Sc Ag | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents |
| UA108760C2 (uk) | 2010-07-01 | 2015-06-10 | Кальцієві солі сполуки як протизапальні, імуномодулюючі та антипроліферативні засоби | |
| US11730716B2 (en) * | 2014-05-08 | 2023-08-22 | Kiora Pharmaceuticals Gmbh | Compounds for treating ophthalmic diseases and disorders |
| WO2017117372A1 (en) * | 2015-12-30 | 2017-07-06 | Agios Pharmaceuticals, Inc. | Treatment of tumors incorporating mutant isocitrate dehydrogenase |
-
2019
- 2019-03-15 MA MA051998A patent/MA51998A/fr unknown
- 2019-03-15 KR KR1020207026564A patent/KR20200131249A/ko not_active Application Discontinuation
- 2019-03-15 IL IL277326A patent/IL277326B2/en unknown
- 2019-03-15 CA CA3093984A patent/CA3093984A1/en active Pending
- 2019-03-15 CN CN201980018653.3A patent/CN111836795B/zh active Active
- 2019-03-15 FI FIEP19711350.9T patent/FI3765439T3/fi active
- 2019-03-15 SG SG11202008032YA patent/SG11202008032YA/en unknown
- 2019-03-15 US US16/981,122 patent/US20210017125A1/en active Pending
- 2019-03-15 WO PCT/EP2019/056560 patent/WO2019175396A1/en active Application Filing
- 2019-03-15 AU AU2019233698A patent/AU2019233698B2/en active Active
- 2019-03-15 EP EP19711350.9A patent/EP3765439B1/en active Active
- 2019-03-15 JP JP2020549636A patent/JP7358373B2/ja active Active
- 2019-03-15 MX MX2020009612A patent/MX2020009612A/es unknown
- 2019-03-15 UA UAA202006622A patent/UA128135C2/uk unknown
- 2019-03-15 DK DK19711350.9T patent/DK3765439T3/da active
- 2019-03-15 BR BR112020017443-2A patent/BR112020017443A2/pt unknown
- 2019-03-15 IL IL307422A patent/IL307422A/en unknown
-
2020
- 2020-09-16 PH PH12020551488A patent/PH12020551488A1/en unknown
-
2023
- 2023-09-25 JP JP2023159416A patent/JP2024001061A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019233698A1 (en) | 2020-09-17 |
| UA128135C2 (uk) | 2024-04-17 |
| CN111836795B (zh) | 2024-03-29 |
| IL277326B2 (en) | 2024-03-01 |
| WO2019175396A1 (en) | 2019-09-19 |
| EP3765439B1 (en) | 2024-05-01 |
| US20210017125A1 (en) | 2021-01-21 |
| RU2020133836A (ru) | 2022-04-18 |
| IL277326A (en) | 2020-10-29 |
| IL307422A (en) | 2023-12-01 |
| IL277326B1 (en) | 2023-11-01 |
| JP2021518359A (ja) | 2021-08-02 |
| FI3765439T3 (fi) | 2024-05-23 |
| SG11202008032YA (en) | 2020-09-29 |
| RU2020133836A3 (da) | 2022-04-18 |
| JP2024001061A (ja) | 2024-01-09 |
| JP7358373B2 (ja) | 2023-10-10 |
| PH12020551488A1 (en) | 2021-08-23 |
| MA51998A (fr) | 2021-01-20 |
| KR20200131249A (ko) | 2020-11-23 |
| BR112020017443A2 (pt) | 2020-12-22 |
| MX2020009612A (es) | 2020-10-07 |
| CA3093984A1 (en) | 2019-09-19 |
| AU2019233698B2 (en) | 2023-01-19 |
| EP3765439A1 (en) | 2021-01-20 |
| CN111836795A (zh) | 2020-10-27 |
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