DK3297637T3 - Benzen-1,3,5-tricarboxamidderivater og anvendelser deraf - Google Patents
Benzen-1,3,5-tricarboxamidderivater og anvendelser deraf Download PDFInfo
- Publication number
- DK3297637T3 DK3297637T3 DK16797375.9T DK16797375T DK3297637T3 DK 3297637 T3 DK3297637 T3 DK 3297637T3 DK 16797375 T DK16797375 T DK 16797375T DK 3297637 T3 DK3297637 T3 DK 3297637T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzene
- tricarboxamide
- derivatives
- tricarboxamide derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562164891P | 2015-05-21 | 2015-05-21 | |
| PCT/US2016/033514 WO2016187531A1 (en) | 2015-05-21 | 2016-05-20 | Benzene-1,3,5-tricarboxamide derivatives and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3297637T3 true DK3297637T3 (da) | 2021-08-02 |
Family
ID=57320926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16797375.9T DK3297637T3 (da) | 2015-05-21 | 2016-05-20 | Benzen-1,3,5-tricarboxamidderivater og anvendelser deraf |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10369122B2 (da) |
| EP (2) | EP3297637B1 (da) |
| DK (1) | DK3297637T3 (da) |
| ES (1) | ES2880103T3 (da) |
| WO (1) | WO2016187531A1 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016171198A1 (ja) * | 2015-04-21 | 2016-10-27 | 国立大学法人東京大学 | 微粒子検出システム及び微粒子検出プログラム |
| US10281374B2 (en) * | 2015-11-04 | 2019-05-07 | Diagnostic Biosystems | Method of pretreatment of biological samples for an analyte-staining assay method |
| US10379015B2 (en) | 2017-06-04 | 2019-08-13 | Diagnostic Biosystems | Method for labeling concentration density differentials of an analyte in a biological sample |
| WO2019099501A1 (en) | 2017-11-14 | 2019-05-23 | Ohio State Innovation Foundation | Benzene-1,3,5-tricarboxamide derived ester lipids and uses thereof |
| KR20220006041A (ko) * | 2019-03-08 | 2022-01-14 | 메사추세츠 인스티튜트 오브 테크놀로지 | 합성 종양용해성 lnp-레플리콘 rna 및 암 면역요법을 위한 용도 |
| KR20220045204A (ko) * | 2019-08-09 | 2022-04-12 | 넛크래커 테라퓨틱스 인코포레이티드 | 핵산 전달을 위한 지질화된 양이온성 펩타이드-peg 조성물 |
| EP4010481A4 (en) | 2019-08-09 | 2023-09-20 | Nutcracker Therapeutics, Inc. | MICROFLUIDIC DEVICES AND METHODS OF USE THEREOF |
| WO2022020811A1 (en) | 2020-07-24 | 2022-01-27 | Strand Therapeutics, Inc. | Lipidnanoparticle comprising modified nucleotides |
| CN114315606B (zh) * | 2020-12-29 | 2023-12-26 | 李斌 | 一种脂样分子及其应用 |
| US20220249693A1 (en) * | 2021-01-20 | 2022-08-11 | Beam Therapeutics Inc. | Nanomaterials |
| WO2023274265A1 (zh) * | 2021-06-29 | 2023-01-05 | 江苏恒瑞医药股份有限公司 | 苯酰胺类化合物及其用途 |
| CZ2021345A3 (cs) | 2021-07-19 | 2023-02-01 | Ăšstav organickĂ© chemie a biochemie AV ÄŚR, v. v. i. | Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití |
| WO2023069498A1 (en) | 2021-10-22 | 2023-04-27 | Senda Biosciences, Inc. | Mrna vaccine composition |
| WO2023096858A1 (en) | 2021-11-23 | 2023-06-01 | Senda Biosciences, Inc. | A bacteria-derived lipid composition and use thereof |
| WO2023121970A1 (en) * | 2021-12-20 | 2023-06-29 | Beam Therapeutics Inc. | Ionizable amine and ester lipids and lipid nanoparticles |
| WO2023122080A1 (en) | 2021-12-20 | 2023-06-29 | Senda Biosciences, Inc. | Compositions comprising mrna and lipid reconstructed plant messenger packs |
| WO2023172948A1 (en) * | 2022-03-08 | 2023-09-14 | Ohio State Innovation Foundation | Ccl5 mrna nanoparticle and methods of use thereof |
| WO2023212618A1 (en) | 2022-04-26 | 2023-11-02 | Strand Therapeutics Inc. | Lipid nanoparticles comprising venezuelan equine encephalitis (vee) replicon and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4411649A (en) * | 1979-07-12 | 1983-10-25 | Baxter Travenol Laboratories, Inc. | Fluid flow control system |
| US4507466A (en) | 1983-01-07 | 1985-03-26 | The Dow Chemical Corporation | Dense star polymers having core, core branches, terminal groups |
| EP0796840A3 (de) * | 1996-03-22 | 1999-01-27 | Witco Vinyl Additives GmbH | Stabilisatoren für chlorhaltige Polymere |
| GB9905771D0 (en) * | 1999-03-12 | 1999-05-05 | Isis Innovation | Compounds |
| CN1174023C (zh) * | 2002-04-12 | 2004-11-03 | 武汉大学 | 一种聚酰胺-胺树型高分子及其制备方法和用途 |
| ATE407176T1 (de) * | 2003-12-30 | 2008-09-15 | Univ California Office Of The | Aromatische triamid-lanthanid-komplexe |
| CN113149869A (zh) * | 2011-10-27 | 2021-07-23 | 麻省理工学院 | 能够形成药物包封微球的在n末端上官能化的氨基酸衍生物 |
-
2016
- 2016-05-20 EP EP16797375.9A patent/EP3297637B1/en active Active
- 2016-05-20 US US15/575,919 patent/US10369122B2/en active Active
- 2016-05-20 WO PCT/US2016/033514 patent/WO2016187531A1/en active Application Filing
- 2016-05-20 ES ES16797375T patent/ES2880103T3/es active Active
- 2016-05-20 DK DK16797375.9T patent/DK3297637T3/da active
- 2016-05-20 EP EP21175822.2A patent/EP3939571A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US10369122B2 (en) | 2019-08-06 |
| EP3297637B1 (en) | 2021-05-26 |
| WO2016187531A1 (en) | 2016-11-24 |
| EP3297637A4 (en) | 2019-01-23 |
| EP3297637A1 (en) | 2018-03-28 |
| ES2880103T3 (es) | 2021-11-23 |
| EP3939571A1 (en) | 2022-01-19 |
| US20180147166A1 (en) | 2018-05-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3297637T3 (da) | Benzen-1,3,5-tricarboxamidderivater og anvendelser deraf | |
| NO2023013I1 (no) | Combination of foslevodopa and foscarbidopa, each in all forms protected by the basic patent | |
| DK3407888T3 (da) | Pyridopyrroloquinoxalinforbindelser, deres sammensætninger og anvendelser | |
| DK3452463T3 (da) | Amidsubstituerede pyridinyltriazolderivater og anvendelser deraf | |
| DK3676297T3 (da) | Forbindelser, sammensætninger og fremgangsmåder | |
| DK3328849T3 (da) | 1,1,1-trifluor-3-hydroxypropan-2-yl-carbamat-derivater og 1,1,1-trifluor-4-hydroxybutan-2-yl-carbamat-derivater som magl-inhibitorer | |
| DK3411358T3 (da) | Substitueret piperidinforbindelse og anvendelse deraf. | |
| DK3307707T3 (da) | Halogensubstituerede phenoxyphenylamidiner og anvendelsen deraf som fungicider | |
| HK1254654A1 (zh) | 4，6-亞嘧啶基衍生物及其用途 | |
| DK3154594T3 (da) | Fap-aktiverede, terapeutiske midler og anvendelser i forbindelser dermed | |
| BR112016018521A2 (pt) | composição, e, kit. | |
| DK3580561T3 (da) | Hla-baserede metoder, sammensætninger og anvendelse heraf | |
| DK3557998T3 (da) | Sammensætninger, kompositioner og anvendelsesmetoder | |
| DK3253762T3 (da) | 9h-pyrrolo-dipyridinderivater. | |
| DK3408326T3 (da) | Elastomerartikler, sammensætninger og fremgangsmåder til fremstilling deraf | |
| DK3137168T3 (da) | Substituerede 4-phenylpiperidiner, deres fremstilling og anvendelse | |
| DK3612579T3 (da) | Pultrudat, fremstilling og anvendelse heraf | |
| DK3236991T3 (da) | Fgf21-derivater og anvendelser deraf | |
| DK3223796T3 (da) | Farmaceutiske sammensætninger, fremstilling og anvendelser deraf | |
| DK3265123T3 (da) | Antistoffer, anvendelser og fremgangsmåder | |
| DK3110837T3 (da) | Tatk-cdkl5-fusionsproteiner, sammensætninger, formule-ringer og anvendelse deraf | |
| DK3128005T3 (da) | Sirp-alfa-variantkonstruktioner og anvendelser deraf | |
| DK3383397T3 (da) | Farmaceutiske sammensætninger indeholdende doravirin, tenofovirdisoproxilfumarat og lamivudin | |
| DK3386956T3 (da) | Fumagillolderivater og polymorfer deraf | |
| DK3365321T3 (da) | Solabegron-zwitterion og anvendelser deraf |