MA51222A - Polymorphes et formes solides d'un composé de pyrimidinylamino-pyrazole, et procédés de production - Google Patents
Polymorphes et formes solides d'un composé de pyrimidinylamino-pyrazole, et procédés de productionInfo
- Publication number
- MA51222A MA51222A MA051222A MA51222A MA51222A MA 51222 A MA51222 A MA 51222A MA 051222 A MA051222 A MA 051222A MA 51222 A MA51222 A MA 51222A MA 51222 A MA51222 A MA 51222A
- Authority
- MA
- Morocco
- Prior art keywords
- pyrimidinylamino
- polymorphs
- production processes
- solid forms
- pyrazole compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762589276P | 2017-11-21 | 2017-11-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA51222A true MA51222A (fr) | 2020-10-07 |
Family
ID=66631734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA051222A MA51222A (fr) | 2017-11-21 | 2018-11-20 | Polymorphes et formes solides d'un composé de pyrimidinylamino-pyrazole, et procédés de production |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US10370361B2 (fr) |
| EP (1) | EP3717473B1 (fr) |
| JP (1) | JP7303821B2 (fr) |
| KR (1) | KR20200089713A (fr) |
| CN (1) | CN111819174A (fr) |
| AR (1) | AR113893A1 (fr) |
| AU (1) | AU2018372180B2 (fr) |
| BR (1) | BR112020010215A2 (fr) |
| CA (1) | CA3083022A1 (fr) |
| CL (1) | CL2020001346A1 (fr) |
| CO (1) | CO2020006206A2 (fr) |
| CR (1) | CR20200216A (fr) |
| EA (1) | EA202091279A1 (fr) |
| ES (1) | ES2975319T3 (fr) |
| IL (1) | IL274824A (fr) |
| JO (1) | JOP20200128A1 (fr) |
| MA (1) | MA51222A (fr) |
| MX (1) | MX2020005332A (fr) |
| PE (1) | PE20210157A1 (fr) |
| SG (1) | SG11202004733WA (fr) |
| TW (1) | TWI823878B (fr) |
| UA (1) | UA126414C2 (fr) |
| WO (1) | WO2019104086A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI823878B (zh) | 2017-11-21 | 2023-12-01 | 美商戴納立製藥公司 | 嘧啶基胺基-吡唑化合物之多晶型物及固體形式及製備方法 |
| CN112088003B (zh) | 2017-12-20 | 2023-10-13 | 戴纳立制药公司 | 制备嘧啶基-4-氨基吡唑化合物的工艺 |
| WO2023174946A1 (fr) | 2022-03-15 | 2023-09-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Méthode précoce et non invasive d'évaluation du risque de maladie de parkinson chez un sujet |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103002875B (zh) | 2010-05-21 | 2016-05-04 | 因塞特控股公司 | Jak抑制剂的局部用制剂 |
| US8354420B2 (en) | 2010-06-04 | 2013-01-15 | Genentech, Inc. | Aminopyrimidine derivatives as LRRK2 inhibitors |
| GB201015949D0 (en) | 2010-09-22 | 2010-11-03 | Medical Res Council Technology | Compounds |
| PL3124483T3 (pl) * | 2010-11-10 | 2020-03-31 | Genentech, Inc. | Pirazolowo-aminopirymidynowe pochodne jako modulatory LRRK2 |
| AR089182A1 (es) | 2011-11-29 | 2014-08-06 | Hoffmann La Roche | Derivados de aminopirimidina como moduladores de lrrk2 |
| BR112014011850B1 (pt) | 2011-11-29 | 2022-01-11 | Genentech, Inc | Derivados de aminopirimidina, seus usos, e composição farmacêutica |
| EP2785709B1 (fr) | 2011-11-29 | 2017-05-10 | Genentech, Inc. | Dérivés aminopyrimidiniques utilisés comme modulateurs de lrrk2 |
| BR112014009717B1 (pt) | 2011-11-29 | 2022-06-14 | Genentech, Inc | Derivados de 2-(fenil ou pirid-3-il)aminopirimidina, seus usos, e composição farmacêutica |
| JP6211061B2 (ja) | 2012-05-03 | 2017-10-11 | ジェネンテック， インコーポレイテッド | パーキンソン病の処置における使用のためのｌｒｒｋ２モジュレーターとしてのピラゾールアミノピリミジン誘導体 |
| MX363118B (es) | 2012-05-03 | 2019-03-11 | Genentech Inc | Derivados de pirazol aminopirimidina como moduladores de cinasa 2 de repeticion rica en leucina (lrrk2). |
| PT3472153T (pt) | 2016-06-16 | 2021-12-31 | Denali Therapeutics Inc | Pirimidin-2-ilamino-1h-pirazóis como inibidores de lrrk2 para uso no tratamento de distúrbios neurodegenerativos |
| TWI823878B (zh) * | 2017-11-21 | 2023-12-01 | 美商戴納立製藥公司 | 嘧啶基胺基-吡唑化合物之多晶型物及固體形式及製備方法 |
-
2018
- 2018-11-20 TW TW107141257A patent/TWI823878B/zh active
- 2018-11-20 BR BR112020010215-6A patent/BR112020010215A2/pt unknown
- 2018-11-20 MA MA051222A patent/MA51222A/fr unknown
- 2018-11-20 UA UAA202003681A patent/UA126414C2/uk unknown
- 2018-11-20 JO JOP/2020/0128A patent/JOP20200128A1/ar unknown
- 2018-11-20 PE PE2020000558A patent/PE20210157A1/es unknown
- 2018-11-20 EA EA202091279A patent/EA202091279A1/ru unknown
- 2018-11-20 ES ES18881859T patent/ES2975319T3/es active Active
- 2018-11-20 CN CN201880081321.5A patent/CN111819174A/zh active Pending
- 2018-11-20 MX MX2020005332A patent/MX2020005332A/es unknown
- 2018-11-20 US US16/197,037 patent/US10370361B2/en active Active
- 2018-11-20 CR CR20200216A patent/CR20200216A/es unknown
- 2018-11-20 WO PCT/US2018/062102 patent/WO2019104086A1/fr active Application Filing
- 2018-11-20 SG SG11202004733WA patent/SG11202004733WA/en unknown
- 2018-11-20 JP JP2020545076A patent/JP7303821B2/ja active Active
- 2018-11-20 AR ARP180103389A patent/AR113893A1/es unknown
- 2018-11-20 KR KR1020207017598A patent/KR20200089713A/ko not_active Application Discontinuation
- 2018-11-20 EP EP18881859.5A patent/EP3717473B1/fr active Active
- 2018-11-20 AU AU2018372180A patent/AU2018372180B2/en active Active
- 2018-11-20 CA CA3083022A patent/CA3083022A1/fr active Pending
-
2019
- 2019-06-20 US US16/447,713 patent/US10851088B2/en active Active
-
2020
- 2020-05-20 IL IL274824A patent/IL274824A/en unknown
- 2020-05-21 CL CL2020001346A patent/CL2020001346A1/es unknown
- 2020-05-21 CO CONC2020/0006206A patent/CO2020006206A2/es unknown
- 2020-11-27 US US17/105,870 patent/US11427571B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3717473A1 (fr) | 2020-10-07 |
| JOP20200128A1 (ar) | 2020-05-21 |
| US10370361B2 (en) | 2019-08-06 |
| UA126414C2 (uk) | 2022-09-28 |
| CA3083022A1 (fr) | 2019-05-31 |
| US10851088B2 (en) | 2020-12-01 |
| ES2975319T3 (es) | 2024-07-04 |
| US20190315723A1 (en) | 2019-10-17 |
| MX2020005332A (es) | 2021-01-08 |
| EP3717473B1 (fr) | 2024-01-10 |
| PE20210157A1 (es) | 2021-01-26 |
| TW201925190A (zh) | 2019-07-01 |
| AR113893A1 (es) | 2020-06-24 |
| BR112020010215A2 (pt) | 2020-11-03 |
| US20210087176A1 (en) | 2021-03-25 |
| WO2019104086A1 (fr) | 2019-05-31 |
| CL2020001346A1 (es) | 2020-11-20 |
| AU2018372180B2 (en) | 2023-08-17 |
| CR20200216A (es) | 2021-03-19 |
| CO2020006206A2 (es) | 2020-08-10 |
| CN111819174A (zh) | 2020-10-23 |
| JP7303821B2 (ja) | 2023-07-05 |
| TWI823878B (zh) | 2023-12-01 |
| US20190194170A1 (en) | 2019-06-27 |
| IL274824A (en) | 2020-07-30 |
| SG11202004733WA (en) | 2020-06-29 |
| KR20200089713A (ko) | 2020-07-27 |
| US11427571B2 (en) | 2022-08-30 |
| AU2018372180A1 (en) | 2020-06-18 |
| JP2021504450A (ja) | 2021-02-15 |
| EA202091279A1 (ru) | 2020-08-19 |
| EP3717473A4 (fr) | 2021-07-07 |
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