MA49503A - Nouveaux récepteurs de lymphocytes t et immunothérapie les utilisant - Google Patents
Nouveaux récepteurs de lymphocytes t et immunothérapie les utilisantInfo
- Publication number
- MA49503A MA49503A MA049503A MA49503A MA49503A MA 49503 A MA49503 A MA 49503A MA 049503 A MA049503 A MA 049503A MA 49503 A MA49503 A MA 49503A MA 49503 A MA49503 A MA 49503A
- Authority
- MA
- Morocco
- Prior art keywords
- immunotherapy
- new
- lymphocyte receptors
- lymphocyte
- receptors
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title 1
- 238000009169 immunotherapy Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/463—Cellular immunotherapy characterised by recombinant expression
- A61K39/4632—T-cell receptors [TCR]; antibody T-cell receptor constructs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8135—Kazal type inhibitors, e.g. pancreatic secretory inhibitor, ovomucoid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- C12N2015/8518—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic expressing industrially exogenous proteins, e.g. for pharmaceutical use, human insulin, blood factors, immunoglobulins, pseudoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Endocrinology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762527844P | 2017-06-30 | 2017-06-30 | |
DE102017114737.3A DE102017114737A1 (de) | 2017-06-30 | 2017-06-30 | Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie |
Publications (1)
Publication Number | Publication Date |
---|---|
MA49503A true MA49503A (fr) | 2020-05-06 |
Family
ID=64662173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA049503A MA49503A (fr) | 2017-06-30 | 2018-06-28 | Nouveaux récepteurs de lymphocytes t et immunothérapie les utilisant |
Country Status (20)
Country | Link |
---|---|
US (4) | US10590194B2 (fr) |
EP (1) | EP3645573A1 (fr) |
JP (1) | JP7235316B2 (fr) |
KR (1) | KR20200023288A (fr) |
CN (1) | CN110753705A (fr) |
AR (1) | AR112604A1 (fr) |
AU (1) | AU2018293322A1 (fr) |
BR (1) | BR112019025323A2 (fr) |
CA (1) | CA3067757A1 (fr) |
CL (1) | CL2019003885A1 (fr) |
CO (1) | CO2020000357A2 (fr) |
CR (1) | CR20190594A (fr) |
DE (1) | DE102017114737A1 (fr) |
IL (1) | IL271751A (fr) |
MA (1) | MA49503A (fr) |
MX (1) | MX2019015742A (fr) |
PE (1) | PE20200337A1 (fr) |
SG (1) | SG11201911437VA (fr) |
TW (1) | TWI727182B (fr) |
WO (1) | WO2019002444A1 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY196837A (en) | 2015-12-11 | 2023-05-03 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against various cancers |
DE102019108125B4 (de) | 2019-03-28 | 2022-02-03 | Immatics US, Inc. | Cd28 t-zellkulturen, zusammensetzungen und verfahren zu deren verwendung |
WO2020191172A1 (fr) | 2019-03-19 | 2020-09-24 | Immatics US, Inc. | Cultures de cellules t cd28, leurs compositions et leurs méthodes d'utilisation |
CR20210669A (es) | 2019-05-27 | 2022-05-05 | Immatics Us Inc | Vectores víricos y uso de los mismos en terapias celulares adoptivas |
US20210032370A1 (en) | 2019-08-02 | 2021-02-04 | Immatics Biotechnologies Gmbh | Recruiting agent further binding an mhc molecule |
CN112442119B (zh) * | 2019-09-05 | 2023-02-24 | 香雪生命科学技术(广东)有限公司 | 一种识别ssx2的高亲和力t细胞受体 |
EP4110901A1 (fr) | 2020-02-24 | 2023-01-04 | immatics US, Inc. | Procédés de multiplication des cellules t pour le traitement du cancer et des malignités connexes |
DE102020111571A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
TW202227616A (zh) | 2020-08-21 | 2022-07-16 | 美商英麥提克斯股份有限公司 | 分離cd8+選擇t細胞的方法 |
DE102021100038A1 (de) | 2020-12-31 | 2022-06-30 | Immatics US, Inc. | Modifizierte cd8-polypeptide, zusammensetzungen und verfahren zu deren verwendung |
CA3203118A1 (fr) | 2020-12-31 | 2022-07-07 | Gagan BAJWA | Polypeptides cd8, compositions et leurs methodes d'utilisation |
CA3217739A1 (fr) | 2021-05-05 | 2022-11-10 | Sebastian Bunk | Polypeptides de liaison a l'antigene bma031 |
US20230089392A1 (en) | 2021-09-20 | 2023-03-23 | Immatics US, Inc. | Monocyte depletion of t cells populations for t-cell therapy |
WO2023081461A1 (fr) | 2021-11-08 | 2023-05-11 | Immatics US, Inc. | Procédés de génération de sphéroïdes cellulaires |
US20230348548A1 (en) | 2022-04-28 | 2023-11-02 | Immatics US, Inc. | Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof |
WO2023212691A1 (fr) | 2022-04-28 | 2023-11-02 | Immatics US, Inc. | Polypeptides récepteurs de tgfβ négatifs dominants, polypeptides cd8, cellules, compositions et leurs méthodes d'utilisation |
US20240066127A1 (en) | 2022-04-28 | 2024-02-29 | Immatics US, Inc. | Il-12 polypeptides, il-15 polypeptides, il-18 polypeptides, cd8 polypeptides, compositions, and methods of using thereof |
WO2023215825A1 (fr) | 2022-05-05 | 2023-11-09 | Immatics US, Inc. | Procédés d'amélioration de l'efficacité d'un lymphocyte t |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0546073T3 (da) | 1990-08-29 | 1998-02-02 | Genpharm Int | Frembringelse og anvendelse af transgene, ikke-humane dyr, der er i stand til at danne heterologe antistoffer |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5714352A (en) | 1996-03-20 | 1998-02-03 | Xenotech Incorporated | Directed switch-mediated DNA recombination |
AU5244499A (en) * | 1998-07-31 | 2000-02-21 | Diagnostic Products Corporation | Polynucleotide encoding an autoantigen associated with endometriosis |
EP1257289A1 (fr) | 2000-02-08 | 2002-11-20 | The Penn State Research Foundation | Utilisation du recepteur de l'interleukine 13, sous-unite alpha 2, dans l'immunotherapie |
GB0525999D0 (en) * | 2005-12-21 | 2006-02-01 | Ares Trading Sa | Novel members of the kazal family of serine protease inhibitors |
MX2009009589A (es) * | 2007-03-05 | 2009-09-21 | Int Inst Cancer Immunology Inc | Gen receptor de celulas t especificas de antigeno cancerigeno, peptido codificado por el gen, y uso de los mismos. |
AU2013300549B2 (en) * | 2012-08-08 | 2019-04-11 | Daiichi Sankyo Company,Limited | Peptide library and use thereof |
JP6628719B2 (ja) * | 2013-07-15 | 2020-01-15 | アメリカ合衆国 | 抗ヒトパピローマウイルス16 e6 t細胞受容体 |
GB201314404D0 (en) * | 2013-08-12 | 2013-09-25 | Immunocore Ltd | T Cell Receptors |
JP6770966B2 (ja) * | 2014-11-05 | 2020-10-21 | ジェネンテック, インコーポレイテッド | 細菌における2鎖タンパク質の生成方法 |
EP3156067A1 (fr) * | 2015-10-16 | 2017-04-19 | Max-Delbrück-Centrum Für Molekulare Medizin | Récepteurs de lymphocytes t hpv à avidité élevée |
GB201520597D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520567D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201521894D0 (en) | 2015-12-11 | 2016-01-27 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against various cancers |
-
2017
- 2017-06-30 DE DE102017114737.3A patent/DE102017114737A1/de active Pending
-
2018
- 2018-06-28 AU AU2018293322A patent/AU2018293322A1/en active Pending
- 2018-06-28 EP EP18737546.4A patent/EP3645573A1/fr active Pending
- 2018-06-28 KR KR1020197036902A patent/KR20200023288A/ko not_active Application Discontinuation
- 2018-06-28 BR BR112019025323-8A patent/BR112019025323A2/pt unknown
- 2018-06-28 CN CN201880033171.0A patent/CN110753705A/zh active Pending
- 2018-06-28 MA MA049503A patent/MA49503A/fr unknown
- 2018-06-28 TW TW107122290A patent/TWI727182B/zh active
- 2018-06-28 SG SG11201911437VA patent/SG11201911437VA/en unknown
- 2018-06-28 PE PE2019002620A patent/PE20200337A1/es unknown
- 2018-06-28 MX MX2019015742A patent/MX2019015742A/es unknown
- 2018-06-28 WO PCT/EP2018/067380 patent/WO2019002444A1/fr unknown
- 2018-06-28 CR CR20190594A patent/CR20190594A/es unknown
- 2018-06-28 JP JP2019569676A patent/JP7235316B2/ja active Active
- 2018-06-28 CA CA3067757A patent/CA3067757A1/fr active Pending
- 2018-06-29 US US16/023,731 patent/US10590194B2/en not_active Expired - Fee Related
- 2018-06-29 AR ARP180101832 patent/AR112604A1/es unknown
-
2019
- 2019-05-03 US US16/403,269 patent/US10723796B2/en active Active
- 2019-12-27 CL CL2019003885A patent/CL2019003885A1/es unknown
- 2019-12-29 IL IL271751A patent/IL271751A/en unknown
-
2020
- 2020-01-03 US US16/733,845 patent/US11111294B2/en active Active
- 2020-01-14 CO CONC2020/0000357A patent/CO2020000357A2/es unknown
-
2021
- 2021-08-09 US US17/397,656 patent/US20210388079A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2020529830A (ja) | 2020-10-15 |
CA3067757A1 (fr) | 2019-01-03 |
EP3645573A1 (fr) | 2020-05-06 |
US10723796B2 (en) | 2020-07-28 |
TWI727182B (zh) | 2021-05-11 |
AU2018293322A1 (en) | 2020-01-16 |
TW201904989A (zh) | 2019-02-01 |
US20190256590A1 (en) | 2019-08-22 |
MX2019015742A (es) | 2020-02-20 |
KR20200023288A (ko) | 2020-03-04 |
WO2019002444A9 (fr) | 2019-03-14 |
AR112604A1 (es) | 2019-11-20 |
DE102017114737A1 (de) | 2019-01-03 |
CL2019003885A1 (es) | 2020-05-29 |
IL271751A (en) | 2020-02-27 |
CO2020000357A2 (es) | 2020-01-31 |
US20200140540A1 (en) | 2020-05-07 |
US11111294B2 (en) | 2021-09-07 |
PE20200337A1 (es) | 2020-02-14 |
CR20190594A (es) | 2020-03-02 |
US10590194B2 (en) | 2020-03-17 |
SG11201911437VA (en) | 2020-01-30 |
BR112019025323A2 (pt) | 2020-06-23 |
US20190002556A1 (en) | 2019-01-03 |
CN110753705A (zh) | 2020-02-04 |
US20210388079A1 (en) | 2021-12-16 |
WO2019002444A1 (fr) | 2019-01-03 |
JP7235316B2 (ja) | 2023-03-08 |
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