DK3180447T3 - Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens - Google Patents

Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens Download PDF

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Publication number
DK3180447T3
DK3180447T3 DK15757372.6T DK15757372T DK3180447T3 DK 3180447 T3 DK3180447 T3 DK 3180447T3 DK 15757372 T DK15757372 T DK 15757372T DK 3180447 T3 DK3180447 T3 DK 3180447T3
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Prior art keywords
analysis
materials
methods
recombination deficiency
homological recombination
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DK15757372.6T
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English (en)
Inventor
Victor Abkevich
Kirsten Timms
Alexander Gutin
Julia Reid
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Myriad Genetics Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Catalysts (AREA)
  • Carbon And Carbon Compounds (AREA)
DK15757372.6T 2014-08-15 2015-08-17 Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens DK3180447T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462037764P 2014-08-15 2014-08-15
US201414507412A 2014-10-06 2014-10-06
PCT/US2015/045561 WO2016025958A1 (en) 2014-08-15 2015-08-17 Methods and materials for assessing homologous recombination deficiency

Publications (1)

Publication Number Publication Date
DK3180447T3 true DK3180447T3 (da) 2020-06-15

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ID=54035301

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15757372.6T DK3180447T3 (da) 2014-08-15 2015-08-17 Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens
DK20162059.8T DK3686288T3 (da) 2014-08-15 2015-08-17 Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens

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DK20162059.8T DK3686288T3 (da) 2014-08-15 2015-08-17 Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens

Country Status (10)

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US (3) US10400287B2 (da)
EP (3) EP4234711A3 (da)
JP (3) JP6877334B2 (da)
AU (2) AU2015301390B2 (da)
CA (1) CA2958801A1 (da)
DK (2) DK3180447T3 (da)
ES (2) ES2800673T3 (da)
NZ (2) NZ728326A (da)
PT (1) PT3180447T (da)
WO (1) WO2016025958A1 (da)

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CN112410423B (zh) * 2020-11-03 2021-08-13 南京世和基因生物技术股份有限公司 同源重组缺失的标志物、检测方法以及检测系统
CN112397145A (zh) * 2020-11-19 2021-02-23 河南省肿瘤医院 一种基于芯片检测的hrd评分计算方法
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JP2024502611A (ja) * 2021-01-10 2024-01-22 エーシーティー ジェノミックス (アイピー) リミテッド 相同組換え修復欠損を判定する方法及びそのキット
CN112820351A (zh) * 2021-03-01 2021-05-18 江苏医联生物科技有限公司 检测肿瘤患者的突变和hrd评分指导用药的方法
CN112980834B (zh) * 2021-04-22 2021-08-17 菁良基因科技(深圳)有限公司 一种同源重组修复缺陷参考品及其制备方法和试剂盒
CN113948151B (zh) * 2021-06-28 2022-07-05 北京橡鑫生物科技有限公司 一种低深度wgs下机数据的处理方法
CN113658638B (zh) * 2021-08-20 2022-06-03 江苏先声医学诊断有限公司 一种基于ngs平台的同源重组缺陷的检测方法和质控体系
CN113462784B (zh) * 2021-08-31 2021-12-10 迈杰转化医学研究(苏州)有限公司 一种构建用于同源重组修复缺陷检测的靶标集合的方法
CN118369439A (zh) * 2021-12-08 2024-07-19 麦利亚德基因公司 用于评估乳腺癌亚型中同源重组缺陷的方法和材料
CN114242170B (zh) * 2021-12-21 2023-05-09 深圳吉因加医学检验实验室 一种同源重组修复缺陷的评估方法、装置和存储介质
CN114283889A (zh) * 2021-12-27 2022-04-05 深圳吉因加医学检验实验室 一种矫正同源重组修复缺陷评分的方法及装置
KR102523938B1 (ko) * 2022-02-04 2023-04-19 가톨릭대학교 산학협력단 상동 재조합 결핍증 예측 모델의 모델링 방법
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Also Published As

Publication number Publication date
AU2015301390A1 (en) 2017-02-02
EP4234711A2 (en) 2023-08-30
US10400287B2 (en) 2019-09-03
EP3180447B1 (en) 2020-03-11
EP3180447A1 (en) 2017-06-21
DK3686288T3 (da) 2023-05-22
NZ728326A (en) 2024-08-30
US20190185939A1 (en) 2019-06-20
AU2015301390B2 (en) 2021-08-26
WO2016025958A1 (en) 2016-02-18
ES2800673T3 (es) 2021-01-04
JP2021112205A (ja) 2021-08-05
EP4234711A3 (en) 2023-09-20
PT3180447T (pt) 2020-06-18
JP7229297B2 (ja) 2023-02-27
EP3686288A1 (en) 2020-07-29
JP2017533693A (ja) 2017-11-16
EP3686288B1 (en) 2023-03-08
JP6877334B2 (ja) 2021-05-26
NZ766822A (en) 2024-08-30
ES2946251T3 (es) 2023-07-14
JP2023015394A (ja) 2023-01-31
CA2958801A1 (en) 2016-02-18
AU2021273600A1 (en) 2021-12-16
US20170283879A1 (en) 2017-10-05
US20230117133A1 (en) 2023-04-20

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