MA35906B1 - Procédé de préparation d'un composé par le biais d'une nouvelle réaction d'addition de michael en utilisant de l'eau ou divers acides comme additifs - Google Patents

Procédé de préparation d'un composé par le biais d'une nouvelle réaction d'addition de michael en utilisant de l'eau ou divers acides comme additifs

Info

Publication number
MA35906B1
MA35906B1 MA37281A MA37281A MA35906B1 MA 35906 B1 MA35906 B1 MA 35906B1 MA 37281 A MA37281 A MA 37281A MA 37281 A MA37281 A MA 37281A MA 35906 B1 MA35906 B1 MA 35906B1
Authority
MA
Morocco
Prior art keywords
michael
additives
water
addition reaction
compound
Prior art date
Application number
MA37281A
Other languages
English (en)
French (fr)
Inventor
Ae Ri Park
Bong Chan Kim
Ji Eun An
Hee Bong Lee
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Publication of MA35906B1 publication Critical patent/MA35906B1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/02Addition
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58Preparation of carboxylic acid halides
    • C07C51/64Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/62Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
MA37281A 2012-02-03 2014-08-12 Procédé de préparation d'un composé par le biais d'une nouvelle réaction d'addition de michael en utilisant de l'eau ou divers acides comme additifs MA35906B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20120011317 2012-02-03
PCT/KR2013/000829 WO2013115595A1 (ko) 2012-02-03 2013-02-01 물 또는 다양한 산을 첨가제로 이용한 새로운 마이클-첨가 반응을 통하여 화합물을 제조하는 방법

Publications (1)

Publication Number Publication Date
MA35906B1 true MA35906B1 (fr) 2014-12-01

Family

ID=48905559

Family Applications (1)

Application Number Title Priority Date Filing Date
MA37281A MA35906B1 (fr) 2012-02-03 2014-08-12 Procédé de préparation d'un composé par le biais d'une nouvelle réaction d'addition de michael en utilisant de l'eau ou divers acides comme additifs

Country Status (16)

Country Link
KR (1) KR101539761B1 (pt)
CN (1) CN104159884B (pt)
AU (1) AU2013215796B2 (pt)
BR (1) BR112014018985B1 (pt)
CL (1) CL2014002029A1 (pt)
CO (1) CO7030967A2 (pt)
EA (1) EA026411B1 (pt)
MA (1) MA35906B1 (pt)
MX (1) MX355336B (pt)
MY (1) MY168411A (pt)
PE (1) PE20142331A1 (pt)
PH (1) PH12014501704B1 (pt)
SG (1) SG11201404396TA (pt)
TN (1) TN2014000329A1 (pt)
WO (1) WO2013115595A1 (pt)
ZA (1) ZA201405598B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9774740B2 (en) 2008-01-28 2017-09-26 Afiniti Europe Technologies Limited Techniques for benchmarking pairing strategies in a contact center system
CN108191647B (zh) * 2018-02-22 2020-09-29 江苏尚莱特医药化工材料有限公司 2,2-二氟二羧酸二烷基酯的合成方法
CN113149823B (zh) * 2021-03-29 2023-12-08 上海青平药业有限公司 一种2-r1戊酸的制备方法
CN113354495A (zh) * 2021-05-20 2021-09-07 上海应用技术大学 一种二氟酮羰基取代不对称腈类化合物及其制备与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS573159B2 (pt) * 1973-12-05 1982-01-20
ATE66469T1 (de) * 1985-01-14 1991-09-15 Neorx Corp Metall-radionuklid markiertes protein fuer diagnose und therapie.
ES2299538T3 (es) * 2001-03-07 2008-06-01 Firmenich Sa Procedimiento para la preparacion de aductos de michael.
BRPI0819719B8 (pt) * 2007-12-21 2021-05-25 Lg Chemical Ltd compostos de inibição de dipeptidil peptidase-iv, métodos de preparação dos mesmos, e preparações farmacêuticas contendo os mesmos como agente ativo

Also Published As

Publication number Publication date
WO2013115595A1 (ko) 2013-08-08
AU2013215796A1 (en) 2014-08-21
CN104159884A (zh) 2014-11-19
SG11201404396TA (en) 2015-06-29
BR112014018985A2 (pt) 2017-06-20
BR112014018985A8 (pt) 2017-07-11
MY168411A (en) 2018-11-09
CO7030967A2 (es) 2014-08-21
ZA201405598B (en) 2015-09-30
CN104159884B (zh) 2016-01-13
MX2014009309A (es) 2014-11-10
MX355336B (es) 2018-04-16
EA026411B1 (ru) 2017-04-28
PH12014501704A1 (en) 2014-10-13
AU2013215796B2 (en) 2016-09-15
PE20142331A1 (es) 2015-01-17
CL2014002029A1 (es) 2014-12-26
EA201491463A1 (ru) 2014-11-28
PH12014501704B1 (en) 2014-10-13
KR20130090360A (ko) 2013-08-13
KR101539761B1 (ko) 2015-07-28
TN2014000329A1 (en) 2015-12-21
BR112014018985B1 (pt) 2021-01-19

Similar Documents

Publication Publication Date Title
MX350892B (es) Síntesis de compuesto antiviral.
MA35128B1 (fr) Nouveaux dérivés d'imidazole utiles pour le traitement de l'arthrite
IN2014CN01136A (pt)
MA35351B1 (fr) Nouveau dérivé 1,2,3,4- tétrahydroquinoléine utile pour le traitement du diabète.
MA40895A (fr) Synthèse de copanlisib et son sel de dichlorhydrate
MA35906B1 (fr) Procédé de préparation d'un composé par le biais d'une nouvelle réaction d'addition de michael en utilisant de l'eau ou divers acides comme additifs
WO2014026657A3 (en) A process for the preparation of a derivative of 2-methyl-2'-phenylpropionic acid using new intermediates
MA35089B1 (fr) Inhibiteurs de la production de leucotrienes de type benzodioxane
MA35886B1 (fr) Dérivés de benzylsulfanilamide utilisés comme inhibiteurs -2 mogat
MA37384A1 (fr) Nouveaux dérivés de thiénopyrimidine, leurs procédés de préparation et leurs utilisations thérapeutiques.
FR3087439B1 (fr) Procédé pour la préparation de 3α-hydroxy-5α-prégnan-20-one (brexanolone)
TN2012000620A1 (fr) Procede de preparation du sel de l-arginine du perindopril
FR2969146B1 (fr) Procede de preparation d'ether de polyol
EA201490998A1 (ru) Способ получения сложных эфиров (5-фтор-2-метил-3-хинолин-2-илметил-индол-1-ил)-уксусной кислоты
MA38410B1 (fr) Composés d'azétidinyloxyphénylpyrrolidine
IN2014DN00144A (pt)
MA38250A1 (fr) Nouveau dérivés d'hydantoïne pour leurs utilisations dans le traitement de maladies, comme l'osteoporose et la thrombocytopenie
IN2013MN02407A (pt)
FR2973377B1 (fr) Derives de la 2,9-dipyridyl-1,10-phenanthroline utiles comme ligands des actinides, leur procede de synthese et leurs utilisations
JP2017052734A (ja) 含フッ素化合物の製造方法
MA38559B1 (fr) Dérivés d'imidazo-triazine utilisés comme inhibiteurs de la pde10
MA20150280A2 (fr) Dérivés d'aryléthynyle
MA39432B1 (fr) Dérivé de tetrahydropyrrolo[3,4-d][1,3]thiazine en tant qu'inhibiteur de bace
MA33130B1 (fr) Synthese chimique amelioree de diaza-indoles par cyclasation de chichibabin
ES2650806T3 (es) Procedimiento para la preparación de bencilaminas disustituidas halogenadas, particularmente dialquilbencilaminas halogenadas