MA35906B1 - Process for the preparation of a compound by means of a new addition reaction of michael using water or various acids as additives - Google Patents

Process for the preparation of a compound by means of a new addition reaction of michael using water or various acids as additives

Info

Publication number
MA35906B1
MA35906B1 MA37281A MA37281A MA35906B1 MA 35906 B1 MA35906 B1 MA 35906B1 MA 37281 A MA37281 A MA 37281A MA 37281 A MA37281 A MA 37281A MA 35906 B1 MA35906 B1 MA 35906B1
Authority
MA
Morocco
Prior art keywords
michael
additives
water
addition reaction
compound
Prior art date
Application number
MA37281A
Other languages
French (fr)
Inventor
Ae Ri Park
Bong Chan Kim
Ji Eun An
Hee Bong Lee
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Publication of MA35906B1 publication Critical patent/MA35906B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/02—Addition
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/64—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/62—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La présente invention concerne un nouveau procédé de préparation d'un composé représenté par la formule chimique 1 en utilisant de l'eau ou divers acides comme additifs dans une réaction d'addition de michael d'un récepteur de michael représenté par la formule chimique 2 et d'un composé représenté par la formule chimique 3.The present invention relates to a novel process for preparing a compound represented by chemical formula 1 using water or various acids as additives in a michael addition reaction of a michael receptor represented by chemical formula 2 and a compound represented by the chemical formula 3.

MA37281A 2012-02-03 2014-08-12 Process for the preparation of a compound by means of a new addition reaction of michael using water or various acids as additives MA35906B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20120011317 2012-02-03
PCT/KR2013/000829 WO2013115595A1 (en) 2012-02-03 2013-02-01 Method for preparing compound by novel michael addition reaction using water or various acids as additive

Publications (1)

Publication Number Publication Date
MA35906B1 true MA35906B1 (en) 2014-12-01

Family

ID=48905559

Family Applications (1)

Application Number Title Priority Date Filing Date
MA37281A MA35906B1 (en) 2012-02-03 2014-08-12 Process for the preparation of a compound by means of a new addition reaction of michael using water or various acids as additives

Country Status (16)

Country Link
KR (1) KR101539761B1 (en)
CN (1) CN104159884B (en)
AU (1) AU2013215796B2 (en)
BR (1) BR112014018985B1 (en)
CL (1) CL2014002029A1 (en)
CO (1) CO7030967A2 (en)
EA (1) EA026411B1 (en)
MA (1) MA35906B1 (en)
MX (1) MX355336B (en)
MY (1) MY168411A (en)
PE (1) PE20142331A1 (en)
PH (1) PH12014501704B1 (en)
SG (1) SG11201404396TA (en)
TN (1) TN2014000329A1 (en)
WO (1) WO2013115595A1 (en)
ZA (1) ZA201405598B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9774740B2 (en) 2008-01-28 2017-09-26 Afiniti Europe Technologies Limited Techniques for benchmarking pairing strategies in a contact center system
CN108191647B (en) * 2018-02-22 2020-09-29 江苏尚莱特医药化工材料有限公司 Synthesis method of 2, 2-difluoro dicarboxylic acid dialkyl ester
CN113149823B (en) * 2021-03-29 2023-12-08 上海青平药业有限公司 2-R 1 Process for preparing valeric acid
CN113354495A (en) * 2021-05-20 2021-09-07 上海应用技术大学 Difluorone carbonyl substituted asymmetric nitrile compound and preparation and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS573159B2 (en) * 1973-12-05 1982-01-20
DE3680924D1 (en) * 1985-01-14 1991-09-26 Neorx Corp METAL RADIONUCLIDE MARKED PROTEIN FOR DIAGNOSIS AND THERAPY.
ATE387421T1 (en) * 2001-03-07 2008-03-15 Firmenich & Cie METHOD FOR PRODUCING MICHAEL ADDUCTS
AU2008341352B2 (en) * 2007-12-21 2013-08-01 Lg Chem, Ltd. Dipeptidyl peptidase-IV inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as active agent

Also Published As

Publication number Publication date
WO2013115595A1 (en) 2013-08-08
PH12014501704A1 (en) 2014-10-13
CN104159884A (en) 2014-11-19
PH12014501704B1 (en) 2014-10-13
KR101539761B1 (en) 2015-07-28
CO7030967A2 (en) 2014-08-21
MY168411A (en) 2018-11-09
BR112014018985A2 (en) 2017-06-20
TN2014000329A1 (en) 2015-12-21
EA201491463A1 (en) 2014-11-28
MX355336B (en) 2018-04-16
ZA201405598B (en) 2015-09-30
MX2014009309A (en) 2014-11-10
AU2013215796A1 (en) 2014-08-21
PE20142331A1 (en) 2015-01-17
SG11201404396TA (en) 2015-06-29
KR20130090360A (en) 2013-08-13
CN104159884B (en) 2016-01-13
EA026411B1 (en) 2017-04-28
CL2014002029A1 (en) 2014-12-26
BR112014018985B1 (en) 2021-01-19
AU2013215796B2 (en) 2016-09-15
BR112014018985A8 (en) 2017-07-11

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