MA33130B1 - Synthese chimique amelioree de diaza-indoles par cyclasation de chichibabin - Google Patents

Synthese chimique amelioree de diaza-indoles par cyclasation de chichibabin

Info

Publication number
MA33130B1
MA33130B1 MA34177A MA34177A MA33130B1 MA 33130 B1 MA33130 B1 MA 33130B1 MA 34177 A MA34177 A MA 34177A MA 34177 A MA34177 A MA 34177A MA 33130 B1 MA33130 B1 MA 33130B1
Authority
MA
Morocco
Prior art keywords
chichibabin
indoles
diaza
cyclasation
chemical synthesis
Prior art date
Application number
MA34177A
Other languages
Arabic (ar)
English (en)
Inventor
George E Lee
Ii Frederick L Shrimp
Franz J Weiberth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MA33130B1 publication Critical patent/MA33130B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

L'invention concerne un procédé de synthèse amélioré pour préparer des diaza-indoles en utilisant une cyclisation de Chichibabin. En particulier, ce procédé est utile pour préparer le composé de formule I.
MA34177A 2009-03-19 2010-03-18 Synthese chimique amelioree de diaza-indoles par cyclasation de chichibabin MA33130B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16144009P 2009-03-19 2009-03-19
FR0958975 2009-12-15
PCT/US2010/027755 WO2010107969A1 (fr) 2009-03-19 2010-03-18 Synthèse chimique améliorée de diaza-indoles par cyclisation de chichibabin

Publications (1)

Publication Number Publication Date
MA33130B1 true MA33130B1 (fr) 2012-03-01

Family

ID=42299194

Family Applications (1)

Application Number Title Priority Date Filing Date
MA34177A MA33130B1 (fr) 2009-03-19 2010-03-18 Synthese chimique amelioree de diaza-indoles par cyclasation de chichibabin

Country Status (18)

Country Link
US (1) US20120010409A1 (fr)
EP (1) EP2408777A1 (fr)
JP (1) JP2012520894A (fr)
KR (1) KR20120001763A (fr)
CN (1) CN102341397A (fr)
AR (1) AR075869A1 (fr)
AU (1) AU2010226618A1 (fr)
BR (1) BRPI1009323A2 (fr)
CA (1) CA2755797A1 (fr)
IL (1) IL215100A0 (fr)
MA (1) MA33130B1 (fr)
MX (1) MX2011008557A (fr)
NZ (1) NZ595175A (fr)
RU (1) RU2011142139A (fr)
SG (1) SG174213A1 (fr)
TW (1) TW201038577A (fr)
UY (1) UY32506A (fr)
WO (1) WO2010107969A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021170881A1 (fr) 2020-02-27 2021-09-02 Syngenta Crop Protection Ag Composés de diazine-bisamide à action pesticide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK288019B6 (sk) * 1999-12-24 2012-11-05 Aventis Pharma Limited Azaindoles derivatives, their use and pharmaceutical composition containing thereof
CL2007002617A1 (es) * 2006-09-11 2008-05-16 Sanofi Aventis Compuestos derivados de pirrolo[2,3-b]pirazin-6-ilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar inflamacion de las articulaciones, artritis reumatoide, tumores, linfoma de las celulas del manto.

Also Published As

Publication number Publication date
WO2010107969A1 (fr) 2010-09-23
JP2012520894A (ja) 2012-09-10
TW201038577A (en) 2010-11-01
SG174213A1 (en) 2011-10-28
RU2011142139A (ru) 2013-04-27
CA2755797A1 (fr) 2010-09-23
MX2011008557A (es) 2011-09-09
AU2010226618A1 (en) 2011-10-06
IL215100A0 (en) 2011-12-29
BRPI1009323A2 (pt) 2016-03-08
NZ595175A (en) 2013-01-25
AR075869A1 (es) 2011-05-04
EP2408777A1 (fr) 2012-01-25
UY32506A (es) 2010-10-29
CN102341397A (zh) 2012-02-01
KR20120001763A (ko) 2012-01-04
US20120010409A1 (en) 2012-01-12

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