MA34963B1 - Derives de fluoro-pyridinone utiles en tant qu'agents antibacteriens - Google Patents
Derives de fluoro-pyridinone utiles en tant qu'agents antibacteriensInfo
- Publication number
- MA34963B1 MA34963B1 MA36233A MA36233A MA34963B1 MA 34963 B1 MA34963 B1 MA 34963B1 MA 36233 A MA36233 A MA 36233A MA 36233 A MA36233 A MA 36233A MA 34963 B1 MA34963 B1 MA 34963B1
- Authority
- MA
- Morocco
- Prior art keywords
- fluoro
- antibacterial agents
- derivatives useful
- pyridinone derivatives
- pyridinone
- Prior art date
Links
- CISUDJRBCKKAGX-UHFFFAOYSA-N 3-fluoro-1h-pyridin-2-one Chemical class OC1=NC=CC=C1F CISUDJRBCKKAGX-UHFFFAOYSA-N 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical class C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161449825P | 2011-03-07 | 2011-03-07 | |
| PCT/IB2012/050812 WO2012120397A1 (en) | 2011-03-07 | 2012-02-22 | Fluoro-pyridinone derivatives useful as antibacterial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA34963B1 true MA34963B1 (fr) | 2014-03-01 |
Family
ID=45841548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA36233A MA34963B1 (fr) | 2011-03-07 | 2012-02-22 | Derives de fluoro-pyridinone utiles en tant qu'agents antibacteriens |
Country Status (34)
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8722686B2 (en) | 2008-09-19 | 2014-05-13 | Pfizer Inc. | Hydroxamic acid derivatives useful as antibacterial agents |
| CA2899583A1 (en) | 2009-12-16 | 2011-06-23 | Pfizer Inc. | N-linked hydroxamic acid derivatives useful as antibacterial agents |
| KR101593288B1 (ko) | 2011-03-07 | 2016-02-11 | 화이자 인코포레이티드 | 항균제로서 유용한 플루오로-피리디논 유도체 |
| AU2012238374B2 (en) | 2011-04-08 | 2015-04-02 | Pfizer Inc. | Isoxazole derivatives useful as antibacterial agents |
| CN103492368A (zh) | 2011-04-08 | 2014-01-01 | 辉瑞大药厂 | 用作抗菌剂的咪唑、吡唑和噻唑衍生物 |
| AR097617A1 (es) * | 2013-09-13 | 2016-04-06 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos del 2h-indazol |
| WO2015085238A1 (en) * | 2013-12-05 | 2015-06-11 | The Regents Of The University Of California, A California Corporation | Inhibitors of lpxc |
| ES2666130T3 (es) * | 2013-12-19 | 2018-05-03 | Idorsia Pharmaceuticals Ltd | Derivados antibacterianos de 1H-indazol y 1H-indol |
| AR099612A1 (es) | 2014-03-04 | 2016-08-03 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona |
| JP6514716B2 (ja) | 2014-04-22 | 2019-05-15 | ノバルティス アーゲー | ＬｐｘＣ阻害剤としてのイソオキサゾリンヒドロキサム酸誘導体 |
| KR20170005105A (ko) * | 2014-05-16 | 2017-01-11 | 액테리온 파마슈티칼 리미티드 | 항균성 퀴나졸린-４(３ｈ)-온 유도체 |
| CN106414429B (zh) | 2014-06-03 | 2020-01-03 | 爱杜西亚药品有限公司 | 吡唑化合物及其作为t型钙通道阻断剂的用途 |
| UA118722C2 (uk) | 2014-11-19 | 2019-02-25 | Ідорсія Фармасьютікалз Лтд | Антибактеріальні бензотіазольні похідні |
| ES2756300T3 (es) | 2014-12-16 | 2020-04-27 | Novartis Ag | Compuestos de ácido isoxazol hidroxámico como inhibidores de LpxC |
| CN104876883B (zh) * | 2015-06-05 | 2017-11-28 | 安徽联创生物医药股份有限公司 | 抗失眠药物苏沃雷生中间体的合成方法 |
| AR105646A1 (es) | 2015-08-11 | 2017-10-25 | Actelion Pharmaceuticals Ltd | Agentes antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituida |
| AR105889A1 (es) * | 2015-09-03 | 2017-11-22 | Actelion Pharmaceuticals Ltd | Compuestos antibacterianos 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituidos |
| AU2017283768B2 (en) | 2016-06-14 | 2019-05-23 | Novartis Ag | Crystalline form of (R)-4-(5-(cyclopropylethynyl)isoxazol-3-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide as an antibacterial agent |
| UA124977C2 (uk) | 2016-12-16 | 2021-12-22 | Ідорсія Фармасьютікалз Лтд | Фармацевтична комбінація, яка містить блокатор кальцієвих каналів т-типу |
| CA3050348A1 (en) | 2017-02-06 | 2018-08-09 | Idorsia Pharmaceuticals Ltd | A novel process for the synthesis of 1-aryl-1-trifluoromethylcyclopropanes |
| RU2754177C1 (ru) * | 2018-03-15 | 2021-08-30 | Пфайзер Инк. | Пиридинон- и пиримидинон-фосфаты и боронаты, полезные в качестве антибактериальных агентов |
| WO2019175828A1 (en) * | 2018-03-15 | 2019-09-19 | Pfizer Inc. | Fluoro-pyridinone phosphates and boronates useful as antibacterial agents |
| CN110699312B (zh) * | 2019-11-28 | 2022-08-12 | 西北农林科技大学 | 一种猪种布鲁氏菌bi-1基因缺失菌株及其构建方法和应用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4769461A (en) | 1986-09-16 | 1988-09-06 | American Home Products Corporation | Quinolinyl benzene hydroxamic acids as anti-inflammatory/antiallergic agents |
| US5110831A (en) | 1990-11-30 | 1992-05-05 | Du Pont Merck Pharmaceutical Company | Vinylogous hydroxamic acids and derivatives thereof as 5-lipoxygenase inhibitors |
| EP1052984B1 (en) | 1998-02-07 | 2004-05-12 | Vernalis (Oxford) Ltd | Antibacterial agents |
| GB9925470D0 (en) | 1999-10-27 | 1999-12-29 | Smithkline Beecham Plc | Novel compounds |
| JPWO2002074298A1 (ja) | 2001-03-21 | 2004-07-08 | 小野薬品工業株式会社 | Ｉｌ−６産生阻害剤 |
| ES2180456B1 (es) | 2001-07-20 | 2004-05-01 | Laboratorios S.A.L.V.A.T., S.A. | Isoxazoles sustituidos y su utilizacion como antibioticos. |
| PT1490064E (pt) * | 2002-02-14 | 2009-12-28 | Pharmacia Corp | Piridinonas substituídas como moduladores de p38 map-quinase |
| AU2004204760C1 (en) | 2003-01-08 | 2010-08-19 | Novartis Vaccines And Diagnostics, Inc. | Antibacterial agents |
| GB0302431D0 (en) | 2003-01-30 | 2003-03-05 | Glaxo Group Ltd | Novel compounds |
| JP2008523098A (ja) | 2004-12-10 | 2008-07-03 | エモリー・ユニバーシテイ | ウィルス感染および異常細胞増殖の治療用の２′および３′−置換シクロブチルヌクレオシド類縁体 |
| WO2006118155A1 (ja) | 2005-04-27 | 2006-11-09 | Ishihara Sangyo Kaisha, Ltd. | ビフェニル誘導体又はその塩、並びにそれらを有効成分として含有する農園芸用殺菌剤 |
| WO2006124897A2 (en) | 2005-05-13 | 2006-11-23 | Lexicon Genetics Incorporated | Methods and compositions for improving cognition |
| US8088804B2 (en) * | 2005-12-15 | 2012-01-03 | Pfizer Inc. | N-hydroxyamide derivatives possessing antibacterial activity |
| WO2008045671A1 (en) | 2006-10-06 | 2008-04-17 | Janssen Pharmaceutica, N.V. | Matrix metalloprotease inhibitors |
| US7879911B2 (en) | 2007-02-01 | 2011-02-01 | Johnson Alan T | Hydroxamic acid derivatives of phenoxy-acetic acids and analogs useful as therapeutic agents for treating anthrax poisoning |
| WO2008105515A1 (ja) | 2007-02-28 | 2008-09-04 | Taisho Pharmaceutical Co., Ltd. | 新規なヒドロキサム酸誘導体 |
| WO2008115262A2 (en) | 2007-03-20 | 2008-09-25 | Curis, Inc. | Hsp90 inhibitors containing a zinc binding moiety |
| CN101239978A (zh) * | 2008-03-05 | 2008-08-13 | 南方医科大学 | 一种咪唑并吡啶类化合物 |
| AU2009279949A1 (en) * | 2008-08-04 | 2010-02-11 | Merck Sharp & Dohme Corp. | Urea derivatives as antibacterial agents |
| WO2010024356A1 (ja) | 2008-08-27 | 2010-03-04 | 大正製薬株式会社 | ナフチリジン－ｎ－オキシドを有する新規ヒドロキサム酸誘導体 |
| US8372885B2 (en) | 2008-09-17 | 2013-02-12 | Novartis Ag | Organic compounds and their uses |
| US8722686B2 (en) | 2008-09-19 | 2014-05-13 | Pfizer Inc. | Hydroxamic acid derivatives useful as antibacterial agents |
| WO2010100475A1 (en) | 2009-03-02 | 2010-09-10 | Astrazeneca Ab | Hydroxamic acid derivatives as gram-negative antibacterial agents |
| WO2010147975A1 (en) * | 2009-06-16 | 2010-12-23 | Schering Corporation | Gamma secretase modulators |
| EP2443121A2 (en) * | 2009-06-16 | 2012-04-25 | Schering Corporation | Gamma secretase modulators |
| CA2899583A1 (en) | 2009-12-16 | 2011-06-23 | Pfizer Inc. | N-linked hydroxamic acid derivatives useful as antibacterial agents |
| KR101593288B1 (ko) | 2011-03-07 | 2016-02-11 | 화이자 인코포레이티드 | 항균제로서 유용한 플루오로-피리디논 유도체 |
| AU2012238374B2 (en) | 2011-04-08 | 2015-04-02 | Pfizer Inc. | Isoxazole derivatives useful as antibacterial agents |
| CN103492368A (zh) | 2011-04-08 | 2014-01-01 | 辉瑞大药厂 | 用作抗菌剂的咪唑、吡唑和噻唑衍生物 |
-
2012
- 2012-02-22 KR KR1020137026034A patent/KR101593288B1/ko not_active Expired - Fee Related
- 2012-02-22 PE PE2013002016A patent/PE20140397A1/es not_active Application Discontinuation
- 2012-02-22 GE GEAP201213215A patent/GEP20156370B/en unknown
- 2012-02-22 ES ES12709179.1T patent/ES2626457T3/es active Active
- 2012-02-22 MA MA36233A patent/MA34963B1/fr unknown
- 2012-02-22 UA UAA201310358A patent/UA107423C2/ru unknown
- 2012-02-22 CN CN201410611970.5A patent/CN104529883A/zh active Pending
- 2012-02-22 EA EA201391072A patent/EA024782B1/ru not_active IP Right Cessation
- 2012-02-22 AU AU2012226473A patent/AU2012226473B8/en active Active
- 2012-02-22 MX MX2013010276A patent/MX341977B/es active IP Right Grant
- 2012-02-22 SG SG2013061643A patent/SG192766A1/en unknown
- 2012-02-22 PH PH1/2013/501780A patent/PH12013501780A1/en unknown
- 2012-02-22 AP AP2013007074A patent/AP3336A/xx active
- 2012-02-22 BR BR112013022536-0A patent/BR112013022536B1/pt active IP Right Grant
- 2012-02-22 CA CA2828337A patent/CA2828337C/en active Active
- 2012-02-22 CN CN201280012230.9A patent/CN103443079B/zh active Active
- 2012-02-22 WO PCT/IB2012/050812 patent/WO2012120397A1/en not_active Ceased
- 2012-02-22 JP JP2013557190A patent/JP5620020B2/ja not_active Expired - Fee Related
- 2012-02-22 EP EP12709179.1A patent/EP2683689B1/en active Active
- 2012-03-05 TW TW101107363A patent/TWI453197B/zh not_active IP Right Cessation
- 2012-03-05 AR ARP120100708A patent/AR085615A1/es unknown
- 2012-03-06 UY UY0001033936A patent/UY33936A/es not_active Application Discontinuation
- 2012-03-07 US US13/414,057 patent/US8624034B2/en active Active
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2013
- 2013-08-20 CR CR20130403A patent/CR20130403A/es unknown
- 2013-08-21 CL CL2013002417A patent/CL2013002417A1/es unknown
- 2013-08-22 IL IL228100A patent/IL228100A0/en unknown
- 2013-08-26 CU CU2013000117A patent/CU20130117A7/es unknown
- 2013-08-27 TN TNP2013000353A patent/TN2013000353A1/fr unknown
- 2013-08-29 ZA ZA2013/06515A patent/ZA201306515B/en unknown
- 2013-09-06 DO DO2013000200A patent/DOP2013000200A/es unknown
- 2013-09-06 GT GT201300213A patent/GT201300213A/es unknown
- 2013-09-06 NI NI201300077A patent/NI201300077A/es unknown
- 2013-09-06 CO CO13211884A patent/CO6761338A2/es active IP Right Grant
- 2013-10-07 EC ECSP13012928 patent/ECSP13012928A/es unknown
- 2013-10-31 US US14/068,956 patent/US8779148B2/en active Active
-
2014
- 2014-06-06 HK HK15110423.9A patent/HK1209734A1/xx unknown
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