MA33692B1 - Procédé de fabrication de composés organiques - Google Patents

Procédé de fabrication de composés organiques

Info

Publication number
MA33692B1
MA33692B1 MA34806A MA34806A MA33692B1 MA 33692 B1 MA33692 B1 MA 33692B1 MA 34806 A MA34806 A MA 34806A MA 34806 A MA34806 A MA 34806A MA 33692 B1 MA33692 B1 MA 33692B1
Authority
MA
Morocco
Prior art keywords
manufacturing
organic compounds
antagonist
receptor
angiotensin receptor
Prior art date
Application number
MA34806A
Other languages
Arabic (ar)
English (en)
Inventor
Gottfried Sedelmeier
Florian Andreas Rampf
Dominique Grimler
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41716392&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA33692(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA33692B1 publication Critical patent/MA33692B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C07C253/34—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/50—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention porte sur des procédés de fabrication d'un bloqueur de récepteur de l'angiotensine (arb; également appelé antagoniste du récepteur il de l'angiotensine ou antagoniste du récepteur at1) et leurs sels, sur de nouveaux intermédiaires et étapes de procédé.
MA34806A 2009-10-27 2012-04-26 Procédé de fabrication de composés organiques MA33692B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09174264A EP2316821A1 (fr) 2009-10-27 2009-10-27 Procédé pour la fabrication de composés organiques
PCT/EP2010/066041 WO2011051213A1 (fr) 2009-10-27 2010-10-25 Procédé de fabrication de composés organiques

Publications (1)

Publication Number Publication Date
MA33692B1 true MA33692B1 (fr) 2012-10-01

Family

ID=41716392

Family Applications (1)

Application Number Title Priority Date Filing Date
MA34806A MA33692B1 (fr) 2009-10-27 2012-04-26 Procédé de fabrication de composés organiques

Country Status (23)

Country Link
US (1) US20120238761A1 (fr)
EP (2) EP2316821A1 (fr)
JP (1) JP2013508436A (fr)
KR (1) KR20120098652A (fr)
CN (1) CN102596899A (fr)
AR (1) AR079104A1 (fr)
AU (1) AU2010311636B2 (fr)
BR (1) BR112012009815A2 (fr)
CA (1) CA2777031A1 (fr)
CL (1) CL2012001081A1 (fr)
CO (1) CO6531487A2 (fr)
EC (1) ECSP12011833A (fr)
IL (1) IL219111A0 (fr)
IN (1) IN2012DN03032A (fr)
MA (1) MA33692B1 (fr)
MX (1) MX2012005025A (fr)
NZ (1) NZ599218A (fr)
PE (1) PE20121501A1 (fr)
RU (1) RU2012121591A (fr)
TN (1) TN2012000154A1 (fr)
TW (1) TW201124389A (fr)
WO (1) WO2011051213A1 (fr)
ZA (1) ZA201202490B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102321038B (zh) * 2011-07-11 2014-03-26 安徽省虹升生物科技有限公司 一种改进的制备缬沙坦方法
FR2981077B1 (fr) * 2011-10-11 2013-11-01 Michelin Soc Tech Methode pour preparer un melange maitre d'elastomere dienique et de silice
WO2018040065A1 (fr) * 2016-09-02 2018-03-08 诺瑞特国际药业股份有限公司 Formes cristallines de sel disodique de valsartan
CN110078640B (zh) * 2019-03-29 2022-04-05 浙江美诺华药物化学有限公司 一种缬沙坦中间体的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874867A (en) 1987-05-22 1989-10-17 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
EP0443983B1 (fr) 1990-02-19 1996-02-28 Ciba-Geigy Ag Composés acylés
JPH04297466A (ja) 1990-06-22 1992-10-21 Nippon Shinyaku Co Ltd テトラゾール誘導体及び医薬
GB9222700D0 (en) * 1992-10-29 1992-12-09 Smithkline Beecham Plc Chemical compounds
GB0222056D0 (en) 2002-09-23 2002-10-30 Novartis Ag Process for the manufacture of organic compounds
GB0316546D0 (en) * 2003-07-15 2003-08-20 Novartis Ag Process for the manufacture of organic compounds
ITMI20032267A1 (it) 2003-11-21 2005-05-22 Dinamite Dipharma S P A In Forma A Bbreviata Diph Procdimento per la preparzione di valsartan e suoi intermedi
HRP20030965A2 (en) * 2003-11-24 2005-08-31 Belupo - Lijekovi I Kozmetika D.D. Process for production of (s)-n-pentanoyl-n-[[2'-(
EP1714963A1 (fr) * 2005-04-19 2006-10-25 IPCA Laboratories Limited Procédé pour la préparation du Valsartan et de ses intermédiaires
JP2009504800A (ja) * 2005-08-22 2009-02-05 アレンビク リミテッド バルサルタンの調製方法
EP2057132A2 (fr) * 2006-07-03 2009-05-13 Aurobindo Pharma Limited Procede ameliore de prparation d'un antagoniste de l'angiotensine ii
CN101450917B (zh) * 2007-12-06 2012-07-11 浙江海正药业股份有限公司 缬沙坦的合成方法
US7943794B2 (en) * 2008-02-13 2011-05-17 Ranbaxy Laboratories Limited Processes for the preparation of intermediates of valsartan

Also Published As

Publication number Publication date
CL2012001081A1 (es) 2013-06-14
WO2011051213A1 (fr) 2011-05-05
BR112012009815A2 (pt) 2016-10-18
KR20120098652A (ko) 2012-09-05
NZ599218A (en) 2014-02-28
TW201124389A (en) 2011-07-16
EP2493848A1 (fr) 2012-09-05
EP2316821A1 (fr) 2011-05-04
AR079104A1 (es) 2011-12-28
MX2012005025A (es) 2012-06-08
CN102596899A (zh) 2012-07-18
ECSP12011833A (es) 2012-06-29
TN2012000154A1 (en) 2013-12-12
US20120238761A1 (en) 2012-09-20
IN2012DN03032A (fr) 2015-07-31
IL219111A0 (en) 2012-06-28
CA2777031A1 (fr) 2011-05-05
CO6531487A2 (es) 2012-09-28
JP2013508436A (ja) 2013-03-07
PE20121501A1 (es) 2012-11-15
AU2010311636A1 (en) 2012-05-03
ZA201202490B (en) 2012-12-27
RU2012121591A (ru) 2013-12-10
AU2010311636B2 (en) 2014-03-06

Similar Documents

Publication Publication Date Title
CY1118332T1 (el) Μεθοδοι παραγωγης κυκλοαλκυλκαρβοξamιδο-πυριδιno βενζοϊκων οξεων
BRPI0914092A2 (pt) método de produção de um anticorpo a partir de células plasmáticas, método de produção de um anticorpo monoclonal a partir de células plasmáticas, método de produção de um anticorpo ou de um fragmento de anticorpo, anticorpo isolado ou fragmento de anticorpo, anticorpo ou fragmento de anticorpo e composição farmacêutica
WO2010008847A3 (fr) Inhibiteurs de pi3k/m tor
LTC3214083I2 (lt) Kvinolono junginių gamybos būdas
EA200800549A1 (ru) Региоселективный способ получения бензимидазолтиофенов
MA34520B1 (fr) Anticorps se liant à la myostatine, compositions et procédés
EA201100517A1 (ru) Способ получения дабигатрана и его промежуточные соединения
PT2470546E (pt) Compostos de hexa-hidrooxazinopteridina para serem utilizados como inibidores de mtor
MY150596A (en) Hsp90 inhibitors
EA201270212A1 (ru) Способ изготовления элемента, содержащего минеральное волокно, и элемент, изготовленный этим способом
CL2009000503A1 (es) Proceso de preparacion de compuestos derivados de acido 2-amino-5-cianobenzoico-3-sustituidos o 1h-pirazol-5-carboxamida.
BR112012009823A2 (pt) poliuretano dispersível em água
WO2010070658A3 (fr) Procédé amélioré de synthèse d'antagonistes de récepteur de l'endothéline
FR2935703B1 (fr) Procede de preparation de composes fluores.
EA201070467A1 (ru) Способ модификации твердого состояния соединения и соаморфные композиции, полученные этим способом
MA33692B1 (fr) Procédé de fabrication de composés organiques
GB2462730B (en) Microtome for producing sections of specimens
HU0800209D0 (en) Syngas made of organic wasts, method for formation of it
IT1391068B1 (it) Metodo per la produzione di silicio policristallino
EP2310611A4 (fr) Procédé de détermination de zone morte de soupape
EP2112186A4 (fr) Procédé pour la production d'un copolymère en blocs
BRPI1016111A2 (pt) "método de produzir aço"
BRPI0914365A2 (pt) ''método de produção de fluoropropeno''
EP2050735A4 (fr) Méthode de production d'un composé 3-amino-azoté optiquement actif
DE602007012935D1 (de) Aminothiazolmakrocyclen, ihre verwendung als antibakterielle verbindungen und verfahren zu ihrer herstellung