MA33223B1 - Thiatriazacyclopentazulenes comme inhibiteurs des pi3-kinases pour le traitement d'un cancer - Google Patents
Thiatriazacyclopentazulenes comme inhibiteurs des pi3-kinases pour le traitement d'un cancerInfo
- Publication number
- MA33223B1 MA33223B1 MA34284A MA34284A MA33223B1 MA 33223 B1 MA33223 B1 MA 33223B1 MA 34284 A MA34284 A MA 34284A MA 34284 A MA34284 A MA 34284A MA 33223 B1 MA33223 B1 MA 33223B1
- Authority
- MA
- Morocco
- Prior art keywords
- tiatriazacyclopentzoline
- cancer treatment
- inhibitors kinases
- kinases
- inhibitors
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 108091000080 Phosphotransferase Proteins 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 102000020233 phosphotransferase Human genes 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 abstract 2
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LA PRÉSENTE INVENTION PORTE SUR DES COMPOSÉS REPRÉSENTÉS PAR LA FORMULE GÉNÉRALE (1) DANS LAQUELLE R1 À R3 ET X SONT TELS QUE DÉFINIS DANS LA REVENDICATION 1, QUI SONT APPROPRIÉS POUR LE TRAITEMENT DE MALADIES CARACTÉRISÉES PAR UNE PROLIFÉRATION CELLULAIRE EXCESSIVE OU ANORMALE, ET SUR LEUR UTILISATION POUR LA PRÉPARATION D'UN MÉDICAMENT AYANT LES PROPRIÉTÉS SUSMENTIONNÉES.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09158493 | 2009-04-22 | ||
PCT/EP2010/055295 WO2010122071A1 (fr) | 2009-04-22 | 2010-04-21 | Thiatriazacyclopentazulènes comme inhibiteurs des pi3-kinases pour le traitement d'un cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
MA33223B1 true MA33223B1 (fr) | 2012-04-02 |
Family
ID=40996623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA34284A MA33223B1 (fr) | 2009-04-22 | 2010-04-21 | Thiatriazacyclopentazulenes comme inhibiteurs des pi3-kinases pour le traitement d'un cancer |
Country Status (21)
Country | Link |
---|---|
US (1) | US8288379B2 (fr) |
EP (1) | EP2421871B1 (fr) |
JP (1) | JP5658231B2 (fr) |
KR (1) | KR20120014152A (fr) |
CN (1) | CN102459282A (fr) |
AP (1) | AP2011005893A0 (fr) |
AR (1) | AR076364A1 (fr) |
AU (1) | AU2010240965A1 (fr) |
BR (1) | BRPI1016174A2 (fr) |
CA (1) | CA2759595A1 (fr) |
CO (1) | CO6460760A2 (fr) |
EA (1) | EA201101537A1 (fr) |
EC (1) | ECSP11011464A (fr) |
IL (1) | IL215199A0 (fr) |
MA (1) | MA33223B1 (fr) |
MX (1) | MX2011011065A (fr) |
SG (1) | SG175746A1 (fr) |
TN (1) | TN2011000530A1 (fr) |
TW (1) | TW201103942A (fr) |
UY (1) | UY32566A (fr) |
WO (1) | WO2010122071A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20160091060A (ko) | 2015-01-23 | 2016-08-02 | 전관식 | 약제 분배장치 및 분말약 분배방법 |
ITRM20150212A1 (it) * | 2015-05-15 | 2016-11-15 | Univ Degli Studi Di Palermo | 4,5,6,9-tetraidropirrolo[2',3':3,4] cicloepta[1,2-d] isossazoli, procedimento per la loro produzione e loro uso come antitumorali |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9024A (en) * | 1852-06-15 | Motion of the lay in looms | ||
US5547975A (en) * | 1994-09-20 | 1996-08-20 | Talley; John J. | Benzopyranopyrazolyl derivatives for the treatment of inflammation |
UY29149A1 (es) | 2004-10-07 | 2006-05-31 | Boehringer Ingelheim Int | Tiazolil-dihidro-indazoles |
KR20070064660A (ko) | 2004-10-07 | 2007-06-21 | 베링거 인겔하임 인터내셔날 게엠베하 | Pi3 키나제 |
US8779154B2 (en) * | 2006-09-26 | 2014-07-15 | Qinglin Che | Fused ring compounds for inflammation and immune-related uses |
US9243000B2 (en) * | 2009-04-22 | 2016-01-26 | Boehringer Ingelheim International Gmbh | Thia-triaza-indacenes |
-
2010
- 2010-04-20 US US12/763,537 patent/US8288379B2/en active Active
- 2010-04-21 SG SG2011076478A patent/SG175746A1/en unknown
- 2010-04-21 JP JP2012506483A patent/JP5658231B2/ja active Active
- 2010-04-21 UY UY0001032566A patent/UY32566A/es not_active Application Discontinuation
- 2010-04-21 TW TW099112536A patent/TW201103942A/zh unknown
- 2010-04-21 CN CN2010800281306A patent/CN102459282A/zh active Pending
- 2010-04-21 AU AU2010240965A patent/AU2010240965A1/en not_active Abandoned
- 2010-04-21 EA EA201101537A patent/EA201101537A1/ru unknown
- 2010-04-21 MX MX2011011065A patent/MX2011011065A/es not_active Application Discontinuation
- 2010-04-21 WO PCT/EP2010/055295 patent/WO2010122071A1/fr active Application Filing
- 2010-04-21 AR ARP100101322A patent/AR076364A1/es unknown
- 2010-04-21 CA CA2759595A patent/CA2759595A1/fr not_active Abandoned
- 2010-04-21 EP EP10714018.8A patent/EP2421871B1/fr active Active
- 2010-04-21 KR KR1020117027380A patent/KR20120014152A/ko not_active Application Discontinuation
- 2010-04-21 AP AP2011005893A patent/AP2011005893A0/xx unknown
- 2010-04-21 MA MA34284A patent/MA33223B1/fr unknown
- 2010-04-21 BR BRPI1016174A patent/BRPI1016174A2/pt not_active Application Discontinuation
-
2011
- 2011-09-18 IL IL215199A patent/IL215199A0/en unknown
- 2011-10-20 TN TNP2011000530A patent/TN2011000530A1/en unknown
- 2011-11-11 CO CO11154168A patent/CO6460760A2/es not_active Application Discontinuation
- 2011-11-17 EC EC2011011464A patent/ECSP11011464A/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP2421871B1 (fr) | 2015-09-16 |
CO6460760A2 (es) | 2012-06-15 |
AR076364A1 (es) | 2011-06-08 |
AP2011005893A0 (en) | 2011-10-31 |
JP2012524751A (ja) | 2012-10-18 |
TW201103942A (en) | 2011-02-01 |
IL215199A0 (en) | 2011-12-29 |
SG175746A1 (en) | 2011-12-29 |
EP2421871A1 (fr) | 2012-02-29 |
US8288379B2 (en) | 2012-10-16 |
ECSP11011464A (es) | 2011-12-30 |
TN2011000530A1 (en) | 2013-05-24 |
US20110112087A1 (en) | 2011-05-12 |
CA2759595A1 (fr) | 2010-10-28 |
UY32566A (es) | 2010-11-30 |
EA201101537A1 (ru) | 2012-05-30 |
AU2010240965A1 (en) | 2011-10-20 |
MX2011011065A (es) | 2011-11-04 |
JP5658231B2 (ja) | 2015-01-21 |
BRPI1016174A2 (pt) | 2016-04-19 |
CN102459282A (zh) | 2012-05-16 |
KR20120014152A (ko) | 2012-02-16 |
WO2010122071A1 (fr) | 2010-10-28 |
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