MA32984B1 - Traitement de l'atrophie vaginale chez des femmes souffrant d'un risque de pathologie cardiovasculaire - Google Patents
Traitement de l'atrophie vaginale chez des femmes souffrant d'un risque de pathologie cardiovasculaireInfo
- Publication number
- MA32984B1 MA32984B1 MA34038A MA34038A MA32984B1 MA 32984 B1 MA32984 B1 MA 32984B1 MA 34038 A MA34038 A MA 34038A MA 34038 A MA34038 A MA 34038A MA 32984 B1 MA32984 B1 MA 32984B1
- Authority
- MA
- Morocco
- Prior art keywords
- cardiovascular disease
- women
- treatment
- risk
- vaginal atrophy
- Prior art date
Links
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 3
- 206010003694 Atrophy Diseases 0.000 title 1
- 230000037444 atrophy Effects 0.000 title 1
- PROQIPRRNZUXQM-UHFFFAOYSA-N (16alpha,17betaOH)-Estra-1,3,5(10)-triene-3,16,17-triol Natural products OC1=CC=C2C3CCC(C)(C(C(O)C4)O)C4C3CCC2=C1 PROQIPRRNZUXQM-UHFFFAOYSA-N 0.000 abstract 2
- PROQIPRRNZUXQM-ZXXIGWHRSA-N estriol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H]([C@H](O)C4)O)[C@@H]4[C@@H]3CCC2=C1 PROQIPRRNZUXQM-ZXXIGWHRSA-N 0.000 abstract 2
- 229960001348 estriol Drugs 0.000 abstract 2
- 208000034423 Delivery Diseases 0.000 abstract 1
- 206010071018 Urogenital atrophy Diseases 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000009677 vaginal delivery Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Pregnancy & Childbirth (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
LA PRÉSENTE INVENTION CONCERNE L'UTILISATION D'ESTRIOL DANS LA PRÉPARATION D'UNE FORMULATION PHARMACEUTIQUE POUR ADMINISTRATION VAGINALE, AYANT LA CAPACITÉ D'AUTO-LIMITER L'ABSORPTION D'ESTRIOL. LADITE PRÉPARATION VISE À LA PRÉVENTION ET/OU AU TRAITEMENT DE L'ATROPHIE UROGÉNITALE CHEZ DES FEMMES PRÉSENTANT UNE PROBABILITÉ ÉLEVÉE D'ÊTRE ATTEINTES D'UNE PATHOLOGIE CARDIOVASCULAIRE, OU DE SOUFFRIR OU D'AVOIR SOUFFERT D'UNE PATHOLOGIE CARDIOVASCULAIRE.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200803623A ES2344675B1 (es) | 2008-12-19 | 2008-12-19 | Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular. |
PCT/EP2009/060304 WO2010069621A1 (fr) | 2008-12-19 | 2009-08-07 | Traitement de l'atrophie vaginale chez des femmes souffrant d'un risque de pathologie cardiovasculaire |
Publications (1)
Publication Number | Publication Date |
---|---|
MA32984B1 true MA32984B1 (fr) | 2012-01-02 |
Family
ID=41050933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA34038A MA32984B1 (fr) | 2008-12-19 | 2009-08-07 | Traitement de l'atrophie vaginale chez des femmes souffrant d'un risque de pathologie cardiovasculaire |
Country Status (23)
Country | Link |
---|---|
US (1) | US8835414B2 (fr) |
EP (1) | EP2376086B1 (fr) |
JP (1) | JP2012512818A (fr) |
KR (1) | KR101734380B1 (fr) |
CN (1) | CN102325533A (fr) |
CA (1) | CA2747314C (fr) |
CL (1) | CL2011001493A1 (fr) |
CO (1) | CO6382128A2 (fr) |
CY (1) | CY1120971T1 (fr) |
DK (1) | DK2376086T3 (fr) |
EC (1) | ECSP11011211A (fr) |
ES (2) | ES2344675B1 (fr) |
HR (1) | HRP20182022T1 (fr) |
HU (1) | HUE040394T2 (fr) |
LT (1) | LT2376086T (fr) |
MA (1) | MA32984B1 (fr) |
MX (1) | MX2011006696A (fr) |
PE (1) | PE20120496A1 (fr) |
PL (1) | PL2376086T3 (fr) |
PT (1) | PT2376086T (fr) |
RU (1) | RU2555752C2 (fr) |
SI (1) | SI2376086T1 (fr) |
WO (1) | WO2010069621A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016110839A1 (fr) * | 2015-01-05 | 2016-07-14 | B.G. Negev Technologies And Applications Ltd., At Ben-Gurion University | Nanoparticules et procédés pour leur préparation |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1866M (fr) | 1961-04-07 | 1963-06-17 | Vismara Francesco Spa | Nouveaux éthers des hormones oestrogenes. |
JPH0830004B2 (ja) | 1983-11-14 | 1996-03-27 | コロンビア ラボラトリーズ インコーポレイテッド | 生物接着性組成物およびそれにより治療する方法 |
US5719197A (en) | 1988-03-04 | 1998-02-17 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
WO1991006289A1 (fr) | 1989-10-31 | 1991-05-16 | Watson Laboratories, Inc. | Support muco-adhesif servant a liberer un agent therapeutique |
DK0431719T3 (da) | 1989-10-31 | 1995-02-27 | Columbia Lab Inc | Vaginalt vævsbefugtende præparat |
US5340586A (en) * | 1991-04-12 | 1994-08-23 | University Of Southern California | Methods and formulations for use in treating oophorectomized women |
US5543150A (en) | 1993-09-15 | 1996-08-06 | Columbia Laboratories, Inc. | Method of progesterone delivery and affect thereof |
US5667492A (en) | 1994-10-07 | 1997-09-16 | Columbia Laboratories, Inc. | Use and composition of an anti-sexually transmitted diseases formulation |
AT408067B (de) | 1995-03-17 | 2001-08-27 | Gebro Pharma Gmbh | Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung |
US5741525A (en) | 1995-10-24 | 1998-04-21 | Marshall University Research Corporation | Vaginal pharmaceutical hydrogen peroxide composition |
IT1275816B1 (it) | 1995-10-27 | 1997-10-17 | Montefarmaco Spa | Composizioni farmaceutiche solide per uso vaginale |
AU714797B2 (en) | 1996-06-14 | 2000-01-13 | Mcneil-Ppc, Inc. | Moisture containing compositions that are spreadable onto and adherable to biomembranes, methods of making and use thereof |
IT1284874B1 (it) | 1996-08-02 | 1998-05-22 | Farmigea Spa | Complessi bioadesivi di polycarbophil e farmaci antifungini o antiprotozoari azolici |
US5942243A (en) | 1996-11-12 | 1999-08-24 | Polytherapeutics, Inc. | Mucoadhesive compositions for administration of biologically active agents to animal tissue |
AP1209A (en) | 1996-11-14 | 2003-09-30 | Lipomedica Ehf | Topical formulations containing as a therapeutic active agent fatty acids or fatty alcohols or monoglceride derivatives thereof for treating of mucosa infections. |
DE69819748T2 (de) | 1997-09-12 | 2004-09-30 | Columbia Laboratories (Bermuda) Ltd. | Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen |
US6159491A (en) | 1999-02-12 | 2000-12-12 | Biovector Technologies, Inc. | Prolonged release bioadhesive vaginal gel dosage form |
WO2000050078A1 (fr) | 1999-02-26 | 2000-08-31 | Chiron Corporation | Utilisation de systemes bioadhesifs et d'adjuvants pour l'administration mucosale d'antigenes |
UA74168C2 (uk) | 1999-10-05 | 2005-11-15 | Коламбіа Леборетеріс (Бермуда) Лімітед | Лікування ендометріозу або безпліддя, або покращення плідності та застосування бета-адренергічного агоніста для виробництва лікарського засобу |
WO2001028515A1 (fr) | 1999-10-22 | 2001-04-26 | Líf-Hlaup ehf. Bio-Gels Pharmaceuticals Inc. | Composition pharmaceutique pour le traitement de l'ulceration et/ou erosion epitheliale des muqueuses |
SK288129B6 (sk) * | 2000-01-18 | 2013-10-02 | Bayer Schering Pharma Aktiengesellschaft | Drospirenone for hormonal substitution treatment |
DE60143360D1 (de) | 2000-08-03 | 2010-12-09 | Antares Pharma Ipl Ag | Zusammensetzung zur transdermalen und/oder transmukosalen Verabreichung von Wirkstoffen, die ausreichende therapeutische Spiegel garantiert |
US20040092494A9 (en) | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
JP3655846B2 (ja) | 2001-06-27 | 2005-06-02 | 埼玉日本電気株式会社 | Cdma移動通信システム、及びその呼切断防止方法 |
ES2237298B1 (es) * | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
BRPI0614625A2 (pt) | 2005-08-12 | 2011-04-12 | Drugtech Corp | composição farmacêutica que compreende pelo menos um composto estrogênico, sistema de distribuição de estrogênio vaginal, uso de uma composição e kit que compreende uma pluralidade de cremes vaginais |
US20090124584A1 (en) | 2005-12-16 | 2009-05-14 | Lyle Corporate Development, Inc. | Regeneration of vaginal tissue with non-systemic vaginal administration of estrogen |
KR20090031847A (ko) * | 2006-01-20 | 2009-03-30 | 피어 트리 파머슈티칼스 인코포레이티드 | 위축성 질염을 치료하는 방법 |
EP1872775A1 (fr) * | 2006-06-29 | 2008-01-02 | Polichem S.A. | Emploi d'une matrice hydrophile contenant un dérivé polyacrylique, un éther de cellulose et un désintégrant, pour la production d'un médicament pour le traitement des troubles génitales d'une femme |
WO2008089405A1 (fr) | 2007-01-19 | 2008-07-24 | Neurosci, Inc. | Composition d'hormones multiples administrée par voie vaginale en une seule crème |
ES2310968B1 (es) * | 2007-06-25 | 2010-02-08 | Italfarmaco, S.A. | Uso de estriol en bajas dosis. |
-
2008
- 2008-12-19 ES ES200803623A patent/ES2344675B1/es active Active
-
2009
- 2009-08-07 EP EP09781638.3A patent/EP2376086B1/fr active Active
- 2009-08-07 PL PL09781638T patent/PL2376086T3/pl unknown
- 2009-08-07 RU RU2011127702/15A patent/RU2555752C2/ru active
- 2009-08-07 WO PCT/EP2009/060304 patent/WO2010069621A1/fr active Application Filing
- 2009-08-07 LT LTEP09781638.3T patent/LT2376086T/lt unknown
- 2009-08-07 SI SI200931909T patent/SI2376086T1/sl unknown
- 2009-08-07 KR KR1020117016748A patent/KR101734380B1/ko active IP Right Grant
- 2009-08-07 DK DK09781638.3T patent/DK2376086T3/en active
- 2009-08-07 HU HUE09781638A patent/HUE040394T2/hu unknown
- 2009-08-07 CN CN2009801571799A patent/CN102325533A/zh active Pending
- 2009-08-07 JP JP2011541240A patent/JP2012512818A/ja active Pending
- 2009-08-07 PE PE2011001250A patent/PE20120496A1/es not_active Application Discontinuation
- 2009-08-07 MA MA34038A patent/MA32984B1/fr unknown
- 2009-08-07 CA CA2747314A patent/CA2747314C/fr active Active
- 2009-08-07 PT PT09781638T patent/PT2376086T/pt unknown
- 2009-08-07 ES ES09781638T patent/ES2707873T3/es active Active
- 2009-08-07 MX MX2011006696A patent/MX2011006696A/es active IP Right Grant
- 2009-08-07 US US13/140,602 patent/US8835414B2/en active Active
-
2011
- 2011-06-17 CL CL2011001493A patent/CL2011001493A1/es unknown
- 2011-07-15 EC EC2011011211A patent/ECSP11011211A/es unknown
- 2011-07-19 CO CO11090537A patent/CO6382128A2/es not_active Application Discontinuation
-
2018
- 2018-11-30 HR HRP20182022TT patent/HRP20182022T1/hr unknown
- 2018-12-07 CY CY181101306T patent/CY1120971T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CN102325533A (zh) | 2012-01-18 |
RU2011127702A (ru) | 2013-01-27 |
WO2010069621A8 (fr) | 2011-07-21 |
ES2344675A1 (es) | 2010-09-02 |
RU2555752C2 (ru) | 2015-07-10 |
HUE040394T2 (hu) | 2019-03-28 |
SI2376086T1 (sl) | 2019-02-28 |
WO2010069621A1 (fr) | 2010-06-24 |
CA2747314C (fr) | 2017-04-18 |
US20110312929A1 (en) | 2011-12-22 |
ES2344675B1 (es) | 2011-04-28 |
CY1120971T1 (el) | 2019-12-11 |
MX2011006696A (es) | 2011-07-28 |
JP2012512818A (ja) | 2012-06-07 |
DK2376086T3 (en) | 2018-12-10 |
LT2376086T (lt) | 2019-01-10 |
EP2376086A1 (fr) | 2011-10-19 |
PL2376086T3 (pl) | 2019-05-31 |
ECSP11011211A (es) | 2011-08-31 |
EP2376086B1 (fr) | 2018-09-19 |
KR101734380B1 (ko) | 2017-05-11 |
KR20110108358A (ko) | 2011-10-05 |
US8835414B2 (en) | 2014-09-16 |
CO6382128A2 (es) | 2012-02-15 |
PT2376086T (pt) | 2018-12-18 |
ES2707873T3 (es) | 2019-04-05 |
CL2011001493A1 (es) | 2012-01-13 |
HRP20182022T1 (hr) | 2019-01-25 |
PE20120496A1 (es) | 2012-05-04 |
CA2747314A1 (fr) | 2010-06-24 |
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MA32984B1 (fr) | Traitement de l'atrophie vaginale chez des femmes souffrant d'un risque de pathologie cardiovasculaire |