MA29693B1 - Derives de xanthine en tant qu'agonistes hm74a selectifs - Google Patents
Derives de xanthine en tant qu'agonistes hm74a selectifsInfo
- Publication number
- MA29693B1 MA29693B1 MA30629A MA30629A MA29693B1 MA 29693 B1 MA29693 B1 MA 29693B1 MA 30629 A MA30629 A MA 30629A MA 30629 A MA30629 A MA 30629A MA 29693 B1 MA29693 B1 MA 29693B1
- Authority
- MA
- Morocco
- Prior art keywords
- xanthine derivatives
- hm74a agonists
- compounds
- selective
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Abstract
Dérivés de xanthine servant d'agonistes sélectifs de HM74A La présente invention concerne des composés de formule (I), qui sont des dérivés de xanthine, des procédés pour la production desdits dérivés, des formulations pharmaceutiques contenant les composés actifs et l'utilisation des composés en thérapie, par exemple dans le traitement de maladies pour lesquelles une sous-activation du récepteur HM74A contribue à la maladie ou pour lesquelles l'activation du récepteur sera bénéfique.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0516464A GB0516464D0 (en) | 2005-08-10 | 2005-08-10 | Novel compounds |
GB0607736A GB0607736D0 (en) | 2006-04-19 | 2006-04-19 | Novel compounds |
GB0614569A GB0614569D0 (en) | 2006-07-21 | 2006-07-21 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MA29693B1 true MA29693B1 (fr) | 2008-08-01 |
Family
ID=37189397
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA30628A MA29692B1 (fr) | 2005-08-10 | 2008-02-08 | Derives de la xanthine en tant qu'agonistes selectifs du hm74a |
MA30629A MA29693B1 (fr) | 2005-08-10 | 2008-02-08 | Derives de xanthine en tant qu'agonistes hm74a selectifs |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA30628A MA29692B1 (fr) | 2005-08-10 | 2008-02-08 | Derives de la xanthine en tant qu'agonistes selectifs du hm74a |
Country Status (29)
Country | Link |
---|---|
US (3) | US8143264B2 (fr) |
EP (3) | EP1912991B1 (fr) |
JP (2) | JP2009504592A (fr) |
KR (2) | KR20080034993A (fr) |
AR (1) | AR055369A1 (fr) |
AT (1) | ATE487719T1 (fr) |
AU (2) | AU2006278215A1 (fr) |
BR (2) | BRPI0614270A2 (fr) |
CA (2) | CA2618963A1 (fr) |
CR (2) | CR9749A (fr) |
CY (1) | CY1111757T1 (fr) |
DE (1) | DE602006018151D1 (fr) |
DK (1) | DK1912991T3 (fr) |
EA (2) | EA200800564A1 (fr) |
ES (1) | ES2401128T3 (fr) |
HK (1) | HK1116779A1 (fr) |
HR (1) | HRP20100725T1 (fr) |
IL (2) | IL189081A0 (fr) |
MA (2) | MA29692B1 (fr) |
MX (2) | MX2008001931A (fr) |
MY (1) | MY142067A (fr) |
NO (2) | NO20081212L (fr) |
NZ (1) | NZ565494A (fr) |
PE (1) | PE20070405A1 (fr) |
PL (1) | PL1912991T3 (fr) |
PT (1) | PT1912991E (fr) |
SI (1) | SI1912991T1 (fr) |
TW (1) | TW200800217A (fr) |
WO (2) | WO2007017261A1 (fr) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7495005B2 (en) * | 2002-08-22 | 2009-02-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Xanthine derivatives, their preparation and their use in pharmaceutical compositions |
KR101100601B1 (ko) | 2004-02-14 | 2011-12-29 | 글락소스미스클라인 엘엘씨 | 신규 화합물 |
DE102004030502A1 (de) | 2004-06-24 | 2006-01-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Imidazole und Triazole, deren Herstellung und Verwendung als Arzneimittel |
JP2009504592A (ja) * | 2005-08-10 | 2009-02-05 | スミスクライン・ビーチャム・コーポレイション | 選択的hm74aアゴニストとしてのキサンチン誘導体 |
DE602007010312D1 (de) | 2006-06-23 | 2010-12-16 | Incyte Corp | Purinonderivate als hm74a-agonisten |
EP2044074A2 (fr) | 2006-06-23 | 2009-04-08 | Incyte Corporation | Dérivés de purinone en tant qu'agonistes du hm74a |
RU2009108280A (ru) | 2006-08-08 | 2010-09-20 | Санофи-Авентис (Fr) | Ариламиноарилалкилзамещенные имидазолидин-2,4-дионы, способы их получения, содержащие эти соединения лекарственные средства и их применение |
EP2025674A1 (fr) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament |
DE102007054497B3 (de) | 2007-11-13 | 2009-07-23 | Sanofi-Aventis Deutschland Gmbh | Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung |
WO2010003624A2 (fr) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Composés hétérocycliques, leurs procédés de préparation, médicaments comprenant lesdits composés et leur utilisation |
AU2009324811B2 (en) | 2008-12-08 | 2013-01-24 | Glaxosmithkline Llc | Novel compounds |
WO2010068601A1 (fr) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | Hydrate de fluoroglycoside hétéroaromatique cristallin, ses procédés de fabrication, ses procédés d'utilisation et compositions pharmaceutiques le contenant |
WO2011023754A1 (fr) | 2009-08-26 | 2011-03-03 | Sanofi-Aventis | Nouveaux hydrates de fluoroglycoside hétéroaromatiques cristallins, substances pharmaceutiques comprenant ces composés et leur utilisation |
WO2011107494A1 (fr) | 2010-03-03 | 2011-09-09 | Sanofi | Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation |
KR101799429B1 (ko) | 2010-05-03 | 2017-11-21 | 에스케이바이오팜 주식회사 | 신경 세포 사멸 또는 신경 퇴화를 억제하기 위한 약학적 조성물 |
EP2582709B1 (fr) | 2010-06-18 | 2018-01-24 | Sanofi | Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
EP2606045B1 (fr) * | 2010-08-16 | 2016-01-06 | Boehringer Ingelheim International GmbH | Inhibiteurs à base d'oxadiazole de la production des leucotriènes |
US8580825B2 (en) * | 2010-09-23 | 2013-11-12 | Boehringer Ingelheim International Gmbh | Oxadiazole inhibitors of leukotriene production |
WO2012120054A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation |
EP2683699B1 (fr) | 2011-03-08 | 2015-06-24 | Sanofi | Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation |
US8901114B2 (en) | 2011-03-08 | 2014-12-02 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
EP2683704B1 (fr) | 2011-03-08 | 2014-12-17 | Sanofi | Dérivés oxathiazine ramifiés, procédé pour leur préparation, utilisation en tant que médicament, agents pharmaceutiques contenant ces dérivés et leur utilisation |
WO2013037390A1 (fr) | 2011-09-12 | 2013-03-21 | Sanofi | Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
WO2013045413A1 (fr) | 2011-09-27 | 2013-04-04 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b] pyridine-4-carboxylique utilisés comme inhibiteurs de kinase |
EA201492069A1 (ru) * | 2012-05-30 | 2015-03-31 | Ф.Хоффманн-Ля Рош Аг | Соединения триазола в качестве ингибиторов фосфодиэстеразы 10 (pde10) |
US9359359B2 (en) * | 2013-03-15 | 2016-06-07 | Hydra Biosciences, Inc. | Substituted xanthines and methods of use thereof |
EP2994128B1 (fr) | 2013-05-10 | 2019-01-30 | Gilead Apollo, LLC | Inhibiteurs de l'acc et utilisations associées |
BR112015028152A2 (pt) | 2013-05-10 | 2017-07-25 | Nimbus Apollo Inc | inibidores de acc e usos dos mesmos |
WO2014182943A1 (fr) | 2013-05-10 | 2014-11-13 | Nimbus Apollo, Inc. | Inhibiteurs de l'acc et utilisations associées |
US10208044B2 (en) | 2013-05-10 | 2019-02-19 | Gilead Apollo, Llc | ACC inhibitors and uses thereof |
CN104211702B (zh) * | 2013-05-29 | 2018-08-31 | 中国医学科学院药物研究所 | 取代黄嘌呤类化合物及其制备方法和用途 |
CN105646492B (zh) * | 2014-11-14 | 2019-04-09 | 中国医学科学院药物研究所 | 含五元芳杂环的取代黄嘌呤类化合物及其制备方法和用途 |
DE102017000359A1 (de) | 2016-08-26 | 2018-03-01 | Bihl+Wiedemann Gmbh | Diagnose-Repeater für AS-Interface Netze |
JP7178357B2 (ja) * | 2017-03-07 | 2022-11-25 | エフ.ホフマン-ラ ロシュ アーゲー | オキサジアゾール一過性受容器電位チャネル阻害剤 |
CN112724141A (zh) * | 2021-01-21 | 2021-04-30 | 南京艾美斐生物医药科技有限公司 | 一种gpr109a蛋白受体抑制剂及其制备和应用 |
WO2023150592A2 (fr) * | 2022-02-03 | 2023-08-10 | D.E. Shaw Research, Llc | Composés d'uracile n3-substitués utilisés en tant qu'inhibiteurs de trpa1 |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2797220A (en) * | 1954-12-02 | 1957-06-25 | Univ Michigan | Substituted paraxanthines |
GB8906792D0 (en) * | 1989-03-23 | 1989-05-10 | Beecham Wuelfing Gmbh & Co Kg | Treatment and compounds |
NZ240644A (en) | 1990-11-21 | 1994-08-26 | Smithkline Beecham Corp | Use of xanthine derivatives to inhibit the production of tumour necrosis factor (tnf) |
WO1993016699A1 (fr) | 1992-02-21 | 1993-09-02 | Smithkline Beecham Corporation | Inhibiteurs du facteur necrotique tumoral |
WO1993017684A2 (fr) | 1992-03-04 | 1993-09-16 | Cell Therapeutics, Inc. | Composes a base de xanthine hydroxylee enantiomere |
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US5473070A (en) | 1992-11-16 | 1995-12-05 | Cell Therapeutics, Inc. | Substituted long chain alcohol xanthine compounds |
US6693105B1 (en) * | 1992-11-16 | 2004-02-17 | Cell Therapeutics, Inc. | Hydroxyl-containing compounds |
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WO1995020589A1 (fr) | 1994-01-28 | 1995-08-03 | Cell Therapeutics, Inc. | Inhibiteurs de la signalisation cellulaire |
US6878715B1 (en) * | 1994-02-18 | 2005-04-12 | Cell Therapeutics, Inc. | Therapeutic compounds for inhibiting interleukin-12 signals and method for using same |
US6103730A (en) * | 1994-03-24 | 2000-08-15 | Cell Therapeutics, Inc. | Amine substituted compounds |
CA2183562A1 (fr) * | 1994-02-18 | 1995-08-24 | J. Peter Klein | Mediateurs de signalisation intracellulaire |
US6780865B1 (en) * | 1994-02-18 | 2004-08-24 | Cell Therapeutics, Inc. | Compounds having selective hydrolytic potentials |
US5807861A (en) * | 1994-03-24 | 1998-09-15 | Cell Therapeutics, Inc. | Amine substituted xanthinyl compounds |
US6323201B1 (en) * | 1994-12-29 | 2001-11-27 | The Regents Of The University Of California | Compounds for inhibition of ceramide-mediated signal transduction |
AR015966A1 (es) | 1997-10-17 | 2001-05-30 | Smithkline Beecham Corp | Uso de un compuesto inhibidor de pde4 para la preparacion de un medicamento util para el tratamiento de prurito |
EP1171442B1 (fr) | 1999-04-09 | 2005-12-07 | Cell Therapeutics, Inc. | Derives de xanthine et analogues comme inhibiteurs de transmission des signaux intracellulaires et extracellulaires |
US20030207901A1 (en) * | 1999-07-27 | 2003-11-06 | Cell Therapeutics, Inc. | Hydroxyl-containing compounds |
US6821978B2 (en) * | 2000-09-19 | 2004-11-23 | Schering Corporation | Xanthine phosphodiesterase V inhibitors |
US6586429B2 (en) * | 2000-11-29 | 2003-07-01 | Cell Therapeutics, Inc. | Tricyclic fused xanthine compounds and their uses |
PT1368349E (pt) * | 2001-02-24 | 2007-04-30 | Boehringer Ingelheim Pharma | Derivados de xantina, sua preparação e sua utilização como medicamento |
AU2002242910A1 (en) | 2001-04-11 | 2002-10-28 | Glaxo Group Limited | Medicaments which are modulators of hm74 and/or hm74a activity |
EP1404675B1 (fr) * | 2001-07-03 | 2008-03-12 | Novo Nordisk A/S | Derives de purine inhibiteurs de dpp-iv pour le traitement du diabete |
US7074798B2 (en) | 2002-02-25 | 2006-07-11 | Eisai Co., Ltd | Xanthine derivative and DPPIV inhibitor |
US7482337B2 (en) * | 2002-11-08 | 2009-01-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions |
CN1227492C (zh) * | 2003-03-11 | 2005-11-16 | 张跃 | 一种吸收式空调主体 |
GB0319124D0 (en) * | 2003-08-14 | 2003-09-17 | Smithkline Beecham Corp | Chemical compounds |
KR101100601B1 (ko) * | 2004-02-14 | 2011-12-29 | 글락소스미스클라인 엘엘씨 | 신규 화합물 |
WO2006045564A1 (fr) | 2004-10-22 | 2006-05-04 | Smithkline Beecham Corporation | Derives de xanthine avec activite du recepteur hm74a |
WO2006045565A1 (fr) * | 2004-10-22 | 2006-05-04 | Smithkline Beecham Corporation | Derives de xanthine a activite de recepteur hm74a |
US20090209561A1 (en) * | 2004-10-22 | 2009-08-20 | Richard Jonathan Daniel Hatley | Xanthine Derivatives with HM74A Receptor Activity |
US20080221108A1 (en) * | 2005-02-14 | 2008-09-11 | Richard Hatley | Anthranilic Acid Derivatives As Hm74A Receptor Agonists |
GB0516462D0 (en) * | 2005-08-10 | 2005-09-14 | Smithkline Beecham Corp | Novel compounds |
JP2009504592A (ja) * | 2005-08-10 | 2009-02-05 | スミスクライン・ビーチャム・コーポレイション | 選択的hm74aアゴニストとしてのキサンチン誘導体 |
DE102008009758A1 (de) * | 2008-02-18 | 2009-08-20 | Beiersdorf Ag | Verwendung von 3-(4-Hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-propan-1-on zur verbesserten Hautkonturierung bzw. gegen Cellulite |
AU2009324811B2 (en) | 2008-12-08 | 2013-01-24 | Glaxosmithkline Llc | Novel compounds |
-
2006
- 2006-08-08 JP JP2008525475A patent/JP2009504592A/ja not_active Withdrawn
- 2006-08-08 EA EA200800564A patent/EA200800564A1/ru unknown
- 2006-08-08 EP EP06763016A patent/EP1912991B1/fr active Active
- 2006-08-08 PT PT06763016T patent/PT1912991E/pt unknown
- 2006-08-08 KR KR1020087005717A patent/KR20080034993A/ko not_active Application Discontinuation
- 2006-08-08 DK DK06763016.0T patent/DK1912991T3/da active
- 2006-08-08 EA EA200800555A patent/EA014556B1/ru not_active IP Right Cessation
- 2006-08-08 JP JP2008525474A patent/JP5112316B2/ja not_active Expired - Fee Related
- 2006-08-08 AU AU2006278215A patent/AU2006278215A1/en not_active Abandoned
- 2006-08-08 AR ARP060103459A patent/AR055369A1/es unknown
- 2006-08-08 ES ES10172674T patent/ES2401128T3/es active Active
- 2006-08-08 US US12/063,434 patent/US8143264B2/en not_active Expired - Fee Related
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- 2006-08-08 MY MYPI20063833A patent/MY142067A/en unknown
- 2006-08-08 CA CA002618963A patent/CA2618963A1/fr not_active Abandoned
- 2006-08-08 SI SI200630916T patent/SI1912991T1/sl unknown
- 2006-08-08 CA CA002626723A patent/CA2626723A1/fr not_active Abandoned
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- 2006-08-08 NZ NZ565494A patent/NZ565494A/en not_active IP Right Cessation
- 2006-08-08 EP EP06776699A patent/EP1912992A1/fr not_active Withdrawn
- 2006-08-08 MX MX2008001931A patent/MX2008001931A/es active IP Right Grant
- 2006-08-08 WO PCT/EP2006/007865 patent/WO2007017261A1/fr active Application Filing
- 2006-08-08 WO PCT/EP2006/007869 patent/WO2007017262A1/fr active Application Filing
- 2006-08-08 BR BRPI0615145-0A patent/BRPI0615145A2/pt not_active Application Discontinuation
- 2006-08-08 PE PE2006000963A patent/PE20070405A1/es not_active Application Discontinuation
- 2006-08-08 TW TW095128952A patent/TW200800217A/zh unknown
- 2006-08-08 US US12/063,432 patent/US20100179128A1/en not_active Abandoned
- 2006-08-08 AU AU2006278216A patent/AU2006278216A1/en not_active Abandoned
- 2006-08-08 KR KR1020087005724A patent/KR20080038396A/ko not_active Application Discontinuation
- 2006-08-08 EP EP10172674A patent/EP2272848B1/fr active Active
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- 2006-08-08 DE DE602006018151T patent/DE602006018151D1/de active Active
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2008
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- 2008-02-08 MA MA30628A patent/MA29692B1/fr unknown
- 2008-02-08 MA MA30629A patent/MA29693B1/fr unknown
- 2008-02-21 CR CR9749A patent/CR9749A/es not_active Application Discontinuation
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2010
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2011
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- 2011-04-18 US US13/088,962 patent/US20110257205A1/en not_active Abandoned
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