MA32283B1 - Composes cycliques condenses et utilisation de ceux-ci - Google Patents
Composes cycliques condenses et utilisation de ceux-ciInfo
- Publication number
- MA32283B1 MA32283B1 MA33304A MA33304A MA32283B1 MA 32283 B1 MA32283 B1 MA 32283B1 MA 33304 A MA33304 A MA 33304A MA 33304 A MA33304 A MA 33304A MA 32283 B1 MA32283 B1 MA 32283B1
- Authority
- MA
- Morocco
- Prior art keywords
- cyclic compounds
- condensed cyclic
- relates
- present
- glucokinase activator
- Prior art date
Links
- 150000001923 cyclic compounds Chemical class 0.000 title 1
- 229940124828 glucokinase activator Drugs 0.000 abstract 2
- 208000008589 Obesity Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La présente invention concerne un activateur de glucokinase utile en tant qu'agent pharmaceutique tel qu'un agent pour la prophylaxie ou le traitement du diabète, de l'obésité et similaire. La présente invention concerne un activateur de glucokinase contenant un composé représenté par la formule (i) : dans laquelle chaque symbole est défini dans la spécification, ou un sel de celui-ci ou un promédicament de celui-ci.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008102691 | 2008-04-10 | ||
| PCT/JP2009/057625 WO2009125873A1 (fr) | 2008-04-10 | 2009-04-09 | Composés cycliques condensés et utilisation de ceux-ci |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA32283B1 true MA32283B1 (fr) | 2011-05-02 |
Family
ID=40671202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA33304A MA32283B1 (fr) | 2008-04-10 | 2010-11-01 | Composes cycliques condenses et utilisation de ceux-ci |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US8673942B2 (fr) |
| EP (1) | EP2276760B1 (fr) |
| JP (1) | JP5528348B2 (fr) |
| KR (1) | KR20110002472A (fr) |
| CN (1) | CN102056924B (fr) |
| AR (1) | AR073609A1 (fr) |
| AU (1) | AU2009234666B2 (fr) |
| BR (1) | BRPI0910912A2 (fr) |
| CA (1) | CA2720686A1 (fr) |
| CO (1) | CO6321240A2 (fr) |
| CR (1) | CR11730A (fr) |
| CY (1) | CY1115247T1 (fr) |
| DK (1) | DK2276760T3 (fr) |
| DO (1) | DOP2010000301A (fr) |
| EA (1) | EA019640B1 (fr) |
| EC (1) | ECSP10010602A (fr) |
| ES (1) | ES2476265T3 (fr) |
| GE (1) | GEP20135846B (fr) |
| HR (1) | HRP20140588T1 (fr) |
| IL (1) | IL208463A (fr) |
| MA (1) | MA32283B1 (fr) |
| ME (1) | ME01887B (fr) |
| MX (1) | MX2010011138A (fr) |
| MY (1) | MY152475A (fr) |
| NZ (1) | NZ588562A (fr) |
| PE (1) | PE20100734A1 (fr) |
| PL (1) | PL2276760T3 (fr) |
| PT (1) | PT2276760E (fr) |
| RS (1) | RS53378B (fr) |
| SI (1) | SI2276760T1 (fr) |
| UA (1) | UA104422C2 (fr) |
| UY (1) | UY32131A (fr) |
| WO (1) | WO2009125873A1 (fr) |
| ZA (1) | ZA201007682B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2371826A4 (fr) | 2008-12-29 | 2012-06-27 | Takeda Pharmaceutical | Nouveau composé cyclique condensé et utilisation de celui-ci |
| WO2011107494A1 (fr) | 2010-03-03 | 2011-09-09 | Sanofi | Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| WO2013037390A1 (fr) | 2011-09-12 | 2013-03-21 | Sanofi | Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
| WO2013045413A1 (fr) | 2011-09-27 | 2013-04-04 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b] pyridine-4-carboxylique utilisés comme inhibiteurs de kinase |
| US9719970B2 (en) | 2012-11-30 | 2017-08-01 | Waters Technologies Corporation | Methods and apparatus for the analysis of vitamin D metabolites |
| WO2014099578A1 (fr) * | 2012-12-17 | 2014-06-26 | Merck Sharp & Dohme Corp. | Nouveaux composés activateurs de glucokinase, compositions contenant de tels composés, et méthodes de traitement |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992015301A1 (fr) | 1991-03-01 | 1992-09-17 | H. Lundbeck A/S | Traitement de l'hypertension et de maladies vasculaires peripheriques |
| US6506901B2 (en) | 2000-07-17 | 2003-01-14 | Wyeth | Substituted 2-(S)-hydroxy-3-(piperidin-4-yl-methylamino)-propyl ethers and substituted 2-aryl-2-(R)-hydroxy-1-(piperidin-4-yl-methyl)-ethylamine β-3 adrenergic receptor agonists |
| JPWO2003103648A1 (ja) | 2002-06-05 | 2005-10-06 | 株式会社医薬分子設計研究所 | 糖尿病治療薬 |
| EP1532980A1 (fr) | 2003-11-24 | 2005-05-25 | Novo Nordisk A/S | Carboxamides d'indole n-heteroarylé et leurs analogues, utiles comme des activateurs de glucokinase pour le traitement de diabetes |
| WO2006089397A1 (fr) | 2005-02-22 | 2006-08-31 | Gemin X Biotechnologies Inc. | Procédés pour traiter l’arthrite à l’aide de composés trihétérocycliques |
| EP2308839B1 (fr) * | 2005-04-20 | 2017-03-01 | Takeda Pharmaceutical Company Limited | Composés hétérocycliques condensés |
| AU2006295645B2 (en) | 2005-09-30 | 2011-09-29 | Msd K.K. | 2-heteroaryl-substituted indole derivative |
| US8410087B2 (en) | 2006-10-19 | 2013-04-02 | Takeda Pharmaceutical Company Limited | Indole compound |
| WO2009025478A1 (fr) | 2007-08-17 | 2009-02-26 | Lg Life Sciences Ltd. | Composés d'indole et d'indazole en tant qu'inhibiteurs de nécrose cellulaire |
| CN101896483B (zh) * | 2007-12-20 | 2013-11-20 | 株式会社Lg生命科学 | 葡糖激酶激活剂和包含其作为活性成分的药物组合物 |
| JP5188583B2 (ja) * | 2008-01-04 | 2013-04-24 | エルジー・ライフ・サイエンシーズ・リミテッド | 細胞、組織及び臓器保存効果を有するインドール及びインダゾール誘導体 |
| EP2371826A4 (fr) | 2008-12-29 | 2012-06-27 | Takeda Pharmaceutical | Nouveau composé cyclique condensé et utilisation de celui-ci |
-
2009
- 2009-04-09 AU AU2009234666A patent/AU2009234666B2/en not_active Ceased
- 2009-04-09 DK DK09730930.6T patent/DK2276760T3/da active
- 2009-04-09 NZ NZ588562A patent/NZ588562A/en not_active IP Right Cessation
- 2009-04-09 MY MYPI20104694 patent/MY152475A/en unknown
- 2009-04-09 BR BRPI0910912-9A patent/BRPI0910912A2/pt not_active IP Right Cessation
- 2009-04-09 CN CN200980121846.8A patent/CN102056924B/zh not_active Expired - Fee Related
- 2009-04-09 UA UAA201013332A patent/UA104422C2/uk unknown
- 2009-04-09 PL PL09730930T patent/PL2276760T3/pl unknown
- 2009-04-09 US US12/936,785 patent/US8673942B2/en not_active Expired - Fee Related
- 2009-04-09 EA EA201071180A patent/EA019640B1/ru not_active IP Right Cessation
- 2009-04-09 ME MEP-2014-66A patent/ME01887B/me unknown
- 2009-04-09 RS RS20140324A patent/RS53378B/sr unknown
- 2009-04-09 KR KR1020107025180A patent/KR20110002472A/ko not_active Withdrawn
- 2009-04-09 JP JP2010538248A patent/JP5528348B2/ja not_active Expired - Fee Related
- 2009-04-09 ES ES09730930.6T patent/ES2476265T3/es active Active
- 2009-04-09 WO PCT/JP2009/057625 patent/WO2009125873A1/fr not_active Ceased
- 2009-04-09 MX MX2010011138A patent/MX2010011138A/es active IP Right Grant
- 2009-04-09 GE GEAP2009011998 patent/GEP20135846B/en unknown
- 2009-04-09 CA CA2720686A patent/CA2720686A1/fr not_active Abandoned
- 2009-04-09 HR HRP20140588AT patent/HRP20140588T1/hr unknown
- 2009-04-09 EP EP09730930.6A patent/EP2276760B1/fr active Active
- 2009-04-09 SI SI200930911T patent/SI2276760T1/sl unknown
- 2009-04-09 PT PT97309306T patent/PT2276760E/pt unknown
- 2009-09-18 AR ARP090103590A patent/AR073609A1/es unknown
- 2009-09-21 UY UY0001032131A patent/UY32131A/es not_active Application Discontinuation
- 2009-09-30 PE PE2009001166A patent/PE20100734A1/es not_active Application Discontinuation
-
2010
- 2010-10-04 IL IL208463A patent/IL208463A/en not_active IP Right Cessation
- 2010-10-08 DO DO2010000301A patent/DOP2010000301A/es unknown
- 2010-10-14 CR CR11730A patent/CR11730A/es unknown
- 2010-10-27 ZA ZA2010/07682A patent/ZA201007682B/en unknown
- 2010-11-01 MA MA33304A patent/MA32283B1/fr unknown
- 2010-11-10 EC EC2010010602A patent/ECSP10010602A/es unknown
- 2010-11-10 CO CO10140654A patent/CO6321240A2/es active IP Right Grant
-
2014
- 2014-07-02 CY CY20141100499T patent/CY1115247T1/el unknown
Also Published As
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