MA31666B1 - Cyclic peptide cxcr4 antagonists - Google Patents
Cyclic peptide cxcr4 antagonistsInfo
- Publication number
- MA31666B1 MA31666B1 MA32439A MA32439A MA31666B1 MA 31666 B1 MA31666 B1 MA 31666B1 MA 32439 A MA32439 A MA 32439A MA 32439 A MA32439 A MA 32439A MA 31666 B1 MA31666 B1 MA 31666B1
- Authority
- MA
- Morocco
- Prior art keywords
- cxcr4 peptide
- periodic anti
- periodic
- cxcr4
- peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- AIDS & HIV (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
L'invention concerne des antagonistes cxcr4 de peptides cyclisés par lactame, utiles dans le traitement des cancers, de la polyarthrite rhumatoïde, de la fibrose pulmonaire et de l'infection au vih.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94080207P | 2007-05-30 | 2007-05-30 | |
US94099607P | 2007-05-31 | 2007-05-31 | |
PCT/US2008/064177 WO2008150689A1 (fr) | 2007-05-30 | 2008-05-20 | Antagonistes cxcr4 de peptides cycliques |
Publications (1)
Publication Number | Publication Date |
---|---|
MA31666B1 true MA31666B1 (fr) | 2010-09-01 |
Family
ID=39831600
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA32439A MA31666B1 (fr) | 2007-05-30 | 2009-12-21 | Cyclic peptide cxcr4 antagonists |
Country Status (33)
Country | Link |
---|---|
US (3) | US7691813B2 (fr) |
EP (2) | EP2160221B1 (fr) |
JP (1) | JP5358564B2 (fr) |
KR (2) | KR101169846B1 (fr) |
CN (1) | CN101678213B (fr) |
AR (1) | AR066648A1 (fr) |
AT (1) | ATE516853T1 (fr) |
AU (1) | AU2008260326B2 (fr) |
BR (1) | BRPI0812134A2 (fr) |
CA (1) | CA2688574C (fr) |
CL (1) | CL2008001467A1 (fr) |
CO (1) | CO6241137A2 (fr) |
CR (1) | CR11105A (fr) |
CY (1) | CY1111815T1 (fr) |
DK (1) | DK2160221T3 (fr) |
DO (1) | DOP2009000270A (fr) |
EA (1) | EA017716B1 (fr) |
GT (1) | GT200900304A (fr) |
HK (1) | HK1141474A1 (fr) |
HR (1) | HRP20110551T1 (fr) |
IL (1) | IL201685A (fr) |
JO (1) | JO2776B1 (fr) |
MA (1) | MA31666B1 (fr) |
MX (1) | MX2009012952A (fr) |
MY (1) | MY149432A (fr) |
NZ (1) | NZ580849A (fr) |
PE (1) | PE20090299A1 (fr) |
PL (1) | PL2160221T3 (fr) |
PT (1) | PT2160221E (fr) |
TN (1) | TN2009000496A1 (fr) |
TW (1) | TWI423987B (fr) |
WO (1) | WO2008150689A1 (fr) |
ZA (1) | ZA200908345B (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2942798B1 (fr) * | 2009-03-05 | 2011-04-08 | Centre Nat Rech Scient | Peptides utilisables pour le traitement de la leucemie lymphoide chronique |
IT1397901B1 (it) * | 2010-01-26 | 2013-02-04 | Consiglio Nazionale Ricerche | Peptidi ciclici che legano il recettore cxcr4 e relativi usi in campo medico e diagnostico. |
WO2012118124A1 (fr) * | 2011-03-01 | 2012-09-07 | 国立大学法人京都大学 | Nouvel antagoniste de récepteur de chimiokines |
WO2012168336A1 (fr) * | 2011-06-07 | 2012-12-13 | Polyphor Ag | Peptidomimétiques en épingle à cheveux bêta utilisés comme antagonistes de cxc4 |
CN104780930A (zh) * | 2011-09-30 | 2015-07-15 | 程云 | 丙型肝炎病毒免疫原性肽或其衍生物在预防或治疗关节炎中的应用 |
CA2852160A1 (fr) | 2011-10-28 | 2013-05-02 | Galderma Research & Development | Nouveaux marqueurs d'infiltrat leucocytaire de rosacee et utilisations de ceux-ci |
EP2979991A1 (fr) | 2014-07-31 | 2016-02-03 | Greif International Holding BV. | Matériau multicouche, tapis de protection contre l'incendie avec ce matériau multicouche et ensemble de conteneur de transport et de stockage comprenant ledit tapis de protection contre l'incendie |
DK3050574T3 (da) | 2015-01-28 | 2020-01-20 | Univ Bordeaux | Anvendelse af plerixafor til behandling og/eller forebyggelse af akutte forværringer af kronisk obstruktiv lungesygdom |
WO2017176565A1 (fr) | 2016-04-07 | 2017-10-12 | Eli Lilly And Company | Combinaisons d'un anticorps anti-b7-h1 et d'un agoniste du peptide cxcr4 pour le traitement d'une tumeur solide |
JP7100639B2 (ja) * | 2016-09-06 | 2022-07-13 | メインライン バイオサエンシズ | Cxcr4アンタゴニストおよび使用方法 |
CN106841624B (zh) * | 2017-01-26 | 2019-02-22 | 庄磊靓 | 抗人cd4和抗人cd184单克隆抗体作为标志物的应用 |
CN111183146A (zh) * | 2017-09-05 | 2020-05-19 | 主线生物科学公司 | 高亲和力选择性结合cxcr4的缀合物及其使用方法 |
US11123437B2 (en) | 2017-09-05 | 2021-09-21 | Mainline Biosciences, Inc. | Selective CXCR4 binding peptide conjugate and methods for making and using the same |
US11771736B2 (en) * | 2017-12-21 | 2023-10-03 | Mainline Biosciences (Shanghai) Co., Ltd. | Composition comprising a therapeutic agent and a CXCR4 selective antagonist and methods for using the same |
JP2021165234A (ja) * | 2018-07-03 | 2021-10-14 | 富士フイルム富山化学株式会社 | Cxcr4結合性化合物もしくはその塩またはそれらと金属との錯体 |
AU2019338221B2 (en) | 2018-09-12 | 2024-04-04 | Technische Universität München | CXCR4-targeted diagnostic and therapeutic agents with reduced species selectivity |
US11639373B2 (en) | 2018-09-12 | 2023-05-02 | Technische Universität München | Therapeutic and diagnostic agents for cancer |
EP3956346A4 (fr) * | 2019-04-18 | 2023-01-18 | Provincial Health Services Authority | Nouveaux composés radiomarqués diagnostiques et thérapeutiques ciblant cxcr4 |
EP4097120A4 (fr) * | 2020-01-26 | 2024-05-01 | Mainline Biosciences (Shanghai) Co., Ltd. | Conjugué peptidique de liaison sélective à cxcr4 marqué par isotope et ses procédés de fabrication et d'utilisation |
KR20230124935A (ko) * | 2020-12-25 | 2023-08-28 | 추가이 세이야쿠 가부시키가이샤 | N-치환-아미노산 잔기를 포함하는 펩타이드 화합물의제조 방법 |
EP4043041A1 (fr) | 2021-02-15 | 2022-08-17 | Technische Universität München | Cxcr4-ligands pour usage diagnostique et thérapeutique et leurs précurseurs |
WO2023201435A1 (fr) * | 2022-04-20 | 2023-10-26 | Provincial Health Services Authority | Composés ciblant cxcr4, et leurs procédés de fabrication et d'utilisation |
CN115060901A (zh) * | 2022-06-21 | 2022-09-16 | 中国医学科学院基础医学研究所 | 苹果酸酶2在制备矽肺病或肺纤维化相关疾病诊断试剂或治疗药物中的应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4391123B2 (ja) | 2002-10-24 | 2009-12-24 | 株式会社オーファンリンク | 新規cxcr4アンタゴニスト |
JP5308829B2 (ja) * | 2006-02-27 | 2013-10-09 | テクニッシュ ユニべルシタット ミュンヘン | 癌の画像化および処置 |
-
2008
- 2008-05-20 DK DK08769524.3T patent/DK2160221T3/da active
- 2008-05-20 PE PE2008000868A patent/PE20090299A1/es not_active Application Discontinuation
- 2008-05-20 PL PL08769524T patent/PL2160221T3/pl unknown
- 2008-05-20 WO PCT/US2008/064177 patent/WO2008150689A1/fr active Application Filing
- 2008-05-20 CL CL2008001467A patent/CL2008001467A1/es unknown
- 2008-05-20 PT PT08769524T patent/PT2160221E/pt unknown
- 2008-05-20 KR KR1020097024829A patent/KR101169846B1/ko not_active IP Right Cessation
- 2008-05-20 NZ NZ580849A patent/NZ580849A/en not_active IP Right Cessation
- 2008-05-20 MX MX2009012952A patent/MX2009012952A/es active IP Right Grant
- 2008-05-20 JP JP2010510418A patent/JP5358564B2/ja not_active Expired - Fee Related
- 2008-05-20 CN CN2008800178577A patent/CN101678213B/zh not_active Expired - Fee Related
- 2008-05-20 CA CA2688574A patent/CA2688574C/fr not_active Expired - Fee Related
- 2008-05-20 TW TW097118554A patent/TWI423987B/zh not_active IP Right Cessation
- 2008-05-20 EA EA200971129A patent/EA017716B1/ru not_active IP Right Cessation
- 2008-05-20 AU AU2008260326A patent/AU2008260326B2/en not_active Ceased
- 2008-05-20 EP EP08769524A patent/EP2160221B1/fr active Active
- 2008-05-20 EP EP11172401A patent/EP2377579A1/fr not_active Withdrawn
- 2008-05-20 AR ARP080102137A patent/AR066648A1/es unknown
- 2008-05-20 AT AT08769524T patent/ATE516853T1/de active
- 2008-05-20 US US12/123,574 patent/US7691813B2/en not_active Ceased
- 2008-05-20 MY MYPI20095053A patent/MY149432A/en unknown
- 2008-05-20 BR BRPI0812134-6A2A patent/BRPI0812134A2/pt not_active IP Right Cessation
- 2008-05-20 JO JO2008229A patent/JO2776B1/en active
- 2008-05-20 KR KR1020117026680A patent/KR101319740B1/ko not_active IP Right Cessation
-
2009
- 2009-10-22 IL IL201685A patent/IL201685A/en not_active IP Right Cessation
- 2009-11-10 CR CR11105A patent/CR11105A/es not_active Application Discontinuation
- 2009-11-25 ZA ZA2009/08345A patent/ZA200908345B/en unknown
- 2009-11-26 TN TNP2009000496A patent/TN2009000496A1/fr unknown
- 2009-11-26 GT GT200900304A patent/GT200900304A/es unknown
- 2009-11-27 CO CO09135750A patent/CO6241137A2/es active IP Right Grant
- 2009-11-27 DO DO2009000270A patent/DOP2009000270A/es unknown
- 2009-12-21 MA MA32439A patent/MA31666B1/fr unknown
-
2010
- 2010-01-25 US US12/692,788 patent/US20100130409A1/en not_active Abandoned
- 2010-08-20 HK HK10107961.8A patent/HK1141474A1/xx not_active IP Right Cessation
- 2010-09-10 US US12/807,694 patent/USRE42274E1/en not_active Expired - Fee Related
-
2011
- 2011-07-25 HR HR20110551T patent/HRP20110551T1/hr unknown
- 2011-09-07 CY CY20111100861T patent/CY1111815T1/el unknown
Also Published As
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